Clinical trials: Cancer Of Prostate
Prostate Cancer
Exploring Men s Prostate Cancer Genetic Risk Perceptions
The exploring men's prostate cancer genetic risk perceptions and willingness to give a biospecimen for genetic risk testing study aims to assess prostate cancer genetic risk and susceptibility beliefs among unaffected men of…
- Trial name
- NCT06764992
- Testing
- Questionnaire, Saliva Sample
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Benign Prostatic Hyperplasia, Prostatitis
2013 Annual National Digital Rectal Exam (DRE) Day Study
We aim to determine the effectiveness of 2013 "Mag paDRE ka" programme in increasing general public awareness on prostate health and promoting prostate health assessment among Filipino males aged 40 or older.
- Conditions
- Benign Prostatic Hyperplasia, Prostatitis, Prostate Cancer
- Trial name
- NCT01886547
- Testing
- Prostate health screening
- Where
- Philippines
- Volunteers
- 925 people, healthy volunteers welcome
- Sponsor
- St. Luke's Medical Center, Philippines
Prostate Cancer
Mild Cognitive Impairment in Men Following Androgen Deprivation
MCI with ageing is thought in part to be related to reduced serum sex hormones which is well-recognised, especially in females, but poorly understood.
- Trial name
- NCT01691976
- Testing
- Oestrogen Patches, LHRHa
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
PSA, Elevated PSA
Marker Driven Selection of Patients for Prostate Biopsy and Management
The purpose of this research study is to determine if the interpretation of multiparametric MRI (mpMRI) with an algorithm called habitat risk score (HRS) in combination with a panel of blood and urine biomarkers is more effective…
- Conditions
- PSA, Elevated PSA, Prostate Cancer
- Trial name
- MDSelect (NCT04240327)
- Where
- United States
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- University of Miami
Prostate Cancer, Prostate Neoplasm
Early and Accurate Detection of Prostate Cancer in General Practice
Prostate cancer (PC) is the most common malignancy (4500 new cases/year) and the second leading cause of cancer-associated mortality (1200 deaths/year) among men in Denmark.
- Conditions
- Prostate Cancer, Prostate Neoplasm, Prostate Adenocarcinoma
- Trial name
- NCT03431753
- Testing
- PSA, STHLM3 and mpMRI for PC detection
- Where
- Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Prostatic Neoplasms
PK, PD, Tolerability and Safety of MDPK67b in Healthy Volunteers
This is a Phase I, single centre, prospective, randomized, alternating panels, ascending doses with interspersed placebo, double-blind, crossover trial.
- Trial name
- NCT04839120
- Testing
- MDPK67b
- Where
- Switzerland
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Med Discovery SA
Prostate Cancer
Study Comparing MRI/Ultrasound Fusion-guided Prostate Biopsy Versus Systematic Transrectal Ultrasound-guided Biopsy
Patients will be submitted to a multiparametric MRI examination of the prostate. Subsequently, all participants will be randomized (1:1) into both study arms.
- Trial name
- PROFUSE (NCT02450266)
- Testing
- Systematic transrectal ultrasound-guided prostate biopsy, MRI/ultrasound fusion-guided prostate biopsy
- Where
- 3 sites in Germany
- Volunteers
- 586 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
MR Image Distortion Correction, Prostate Cancer
UNDISTORT Correction of Distortions in Diffusion MRI V1.0
This is a three-year project funded by a Cancer Research UK Multidisciplinary Award and brings together a team from UCL Division of Medicine, Computer Science and University College London Hospital.
- Trial name
- UNDISTORT (NCT03151512)
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University College, London
Androgen Deprivation Therapy, Prostate Cancer
Autonomic and Renal Contributions to Hypertension With ADT
This study plans to learn more about contributors to high blood pressure in men who undergo androgen deprivation therapy (ADT) to treat prostate cancer.
- Conditions
- Androgen Deprivation Therapy, Prostate Cancer, Hypertension, Autonomic Dysfunction
- Trial name
- ARCH (NCT07848828)
- Testing
- Gonadotropin Releasing Hormone Agonists (GNRH), Androgen receptor (AR) inhibitor
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Breast Cancer, Ovarian Cancer
Genetic Testing for Breast, Ovarian, Pancreatic, and Prostate Cancers
This study is evaluating the effect of two pre-test education methods on participants interested in genetic testing for hereditary cancer risk.
- Conditions
- Breast Cancer, Ovarian Cancer, Pancreatic Cancer, Metastatic Prostate Cancer
- Trial name
- GeneBOPP (NCT04330716)
- Testing
- Standard Genetic Counseling, Educational Video
- Where
- 6 sites in United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Prostate Carcinoma
Determination of Baseline Levels for Prostate Cancer-Derived Extracellular Vesicles Following Local Treatment of Prostate Cancer
This study is being done to determine whether levels of prostate cancer derived extracellular vesicles from blood and urine specimens correlate with response to primary local treatment (surgery) in prostate cancer.
- Trial name
- NCT06326216
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Prostate Neoplasm
Addressing Prostate Cancer Information Disparities With eHealth Technology
This is a multicenter study that involves research on screening for prostate cancer. This study pilot tests a culturally appropriate decision aid (DA) for African American (AA) men that will empower them to take part in…
- Trial name
- PCSPrep (NCT02787434)
- Testing
- Prostate Cancer Screening Decision Aid
- Where
- 2 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Tufts University
Prostate Cancer
Randomized Study Comparing MR-guided in Bore Versus MRI/US Fusion-guided Prostate Biopsy
The hypothesis of the study is that targeted MRI/US fusion-guided prostate biopsy with additional systematic transrectal ultrasound (TRUS)-guided biopsy significantly detects more prostate cancers than targeted MR-guided in-bore…
- Trial name
- NCT02220517
- Testing
- MR-guided in-bore prostate biopsy, MRI/US fusion-guided prostate biopsy
- Where
- Germany
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Prostate Cancer
Partial Prostatectomy for Prostate Cancer
A phase 2 study investigation of safety and feasibility of partial prostatectomy for localized prostate cancer of intermediate risk at ICESP.
- Trial name
- P-RALP (NCT06624813)
- Testing
- Robot-assisted partial prostatectomy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Breast Cancer, Cervical Cancer
Cancer Prevention and Treatment Demonstration for Ethnic and Racial Minorities
The goal of this behavioral research study is to improve the use of cancer prevention services, increase early detection, and treatment of cancer.
- Conditions
- Breast Cancer, Cervical Cancer, Prostate Cancer, Colorectal Cancer
- Trial name
- NCT00453661
- Testing
- Questionnaire, Patient Navigator (PN)
- Where
- United States
- Volunteers
- 2,472 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Healthy Volunteers
Comparison of Explicit, Implicit and no Values Clarification Decision Aids for Men Considering Prostate Cancer Screening
The investigators aim at comparing the perceived clarity of personal values in men considering PSA screening using decision aids with no VCM versus an implicit VCM versus an explicit VCM.
- Trial name
- NCT03988673
- Testing
- Decision aid with implicit values clarification method (booklet or website), Decision aid with explicit values clarification method (booklet or website)
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Breast Cancer, Prostate Cancer
Redes III Patient Navigator Qol Study
This proposed 5-year Redes En Acción research study involves a mixed-methods approach that occurs in two phases across two distinct and diverse HL communities.
- Conditions
- Breast Cancer, Prostate Cancer, Colorectal Cancer
- Trial name
- NCT02275754
- Testing
- PN+LCNC, PN Only
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Low Risk Prostate Cancer
Decision Making in Men With Early Stage Prostate Cancer Patients and Partners/Close Allies
The purpose of this study is to collect information on how patients and their partners/close allies make treatment decisions when they have been diagnosed with early stage prostate cancer.
- Trial name
- NCT01877070
- Testing
- assessments
- Where
- 3 sites in United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostate Cancer
Lycopene in Preventing Prostate Cancer in Healthy Participants
RATIONALE: Chemoprevention therapy is the use of certain substances to try to prevent the development or recurrence of cancer. The dietary supplement lycopene may prevent the development of prostate cancer.
- Trial name
- NCT00093561
- Testing
- lycopene
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Hypogonadism, Male, Testosterone Deficiency
Exploring the Relationship Between Androgen Metabolism, Metabolic Disease and Skeletal Muscle Energy Balance in Men
This study relates to men with hypogonadism, a condition describing a deficiency of androgens such as testosterone. Deficiency of these hormones occurs in men due to testicular (primary) or hypothalamic-pituitary (secondary)…
- Conditions
- Hypogonadism, Male, Testosterone Deficiency, Prostate Cancer, Androgen Deficiency
- Trial name
- MMetdMH (NCT05773183)
- Testing
- Testosterone, GnRH
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland