Clinical trials: Cancer Pains
Postoperative Pain
Efficacy of Tramadol With Ropivacaine for Modified Pectoral Nerve Block in Breast Cancer Surgery
In this study the investigators will compare the post operative opoid consumption for patient undergoing modified radical mastectomy.
- Trial name
- NCT07775053
- Testing
- Pectoral Nerve Block
- Where
- Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sargodha Medical College
Neoplasms, Child
VR to Improve CINV, Sleep and Pain Among Children With Cancer in HK
Chemotherapy-induced nausea and vomiting, sleep quality and pain are the common symptoms experienced by children with cancer. These symptoms significantly devastate the children's quality of life.
- Conditions
- Neoplasms, Child, Nausea, Vomiting
- Trial name
- NCT04853303
- Testing
- Hypnosis VR
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Pain, Pulmonary Nodules
Effect of CYP2D6*10 Gene Mutation on Perioperative Precision Analgesia of Oxycodone in Elderly Patients
The purpose of this prospective study was to determine the effect of CYP2D6 gene polymorphism on perioperative analgesia of oxycodone in elderly patients, and to assign the CYP2D6 phenotype according to the genotype, and to use…
- Conditions
- Pain, Pulmonary Nodules, Oxycodone
- Trial name
- NCT07484867
- Testing
- oxycodone
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Henan Provincial People's Hospital
Breast Cancer, Postoperative Pain
PECS Block in Partial Mastectomy for Postoperative Pain Control
The aim of this study is to evaluate patients who are undergoing partial mastectomy or removal of breast tissue and see if a pectoralis nerve block (PECS) can provide a meaningful improvement in postoperative pain control over…
- Conditions
- Breast Cancer, Postoperative Pain, Opioid Use, Local Anesthesia
- Trial name
- PECS (NCT04086394)
- Testing
- Pectoral Nerve Block, Surgery without Nerve Block
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Main Line Health
Cancer Survivor
An Acupuncture Study for Cancer Survivors With Joint Pain
The purpose of this study is to see whether acupuncture is a practical (feasible) treatment for cancer survivors with joint pain.
- Trial name
- NCT06814977
- Testing
- Acupuncture
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer, Educational Problems
The Effect of Education Given at Different Times Before a Breast Biopsy
Aim: This study was conducted to investigate the effect of education given at different times before a breast biopsy on anxiety, readiness for the procedure, pain, and satisfaction levels in women.
- Conditions
- Breast Cancer, Educational Problems, Bypass Complication
- Trial name
- NCT05656612
- Testing
- Written, Oral and Visual Education
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Breast Neoplasms, Survivorship
PI-targeted PNE+MI Compared to BIOMEDICAL Education in BCS
Breast cancer is the most frequently diagnosed cancer in women worldwide. An important portion of the breast cancer survivors will face chronic pain complaints.
- Conditions
- Breast Neoplasms, Survivorship, Pain, Chronic
- Trial name
- BCS-PI (NCT04730154)
- Testing
- Pain Neuroscience Education (PNE), Motivational Interviewing (MI), Biomedically-focused education
- Where
- 4 sites in Belgium
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Hematuria, Bladder Ca
Efficacy of the Act of Urination to Relief the Pain During Flexible Cystoscopy Procedure.
This research is about modification during routine cystoscopy (scope in the bladder) procedure [ experimental research ]. The goal of the study is to evaluate patient experience with cystoscopy by using procedural modification to…
- Conditions
- Hematuria, Bladder Ca, Bladder Stone, Urologic Diseases
- Trial name
- NCT05207969
- Testing
- Instruction to urinate
- Where
- Malaysia
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Uterine Fibroids, Adenomyosis
Effect of Addition of Steroids on Duration of Analgesia
The purpose of the study is to investigate the differences in post-procedural pain scores and narcotic use among patients who receive a Superior Hypogastric Nerve Block (SHNB) with and without corticosteroid performed as part of…
- Trial name
- NCT04126824
- Testing
- Triamcinolone, Bupivacaine, Iohexol contrast
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Cancer
Progressive Relaxation Exercise on Dyspnea, Pain and Sleep Quality
This study was planned to examine the effect of progressive relaxation exercises applied to lung cancer patients receiving chemotherapy on dyspnea, pain and sleep quality.
- Trial name
- Progressive (NCT04978805)
- Testing
- Progressive Relaxation Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Sabahattin Zaim University
Chemotherapy-induced Neutropenia, Chemotherapy-induced Nausea and Vomiting
Community-Led Action Research in Oncology: Improving Symptom Management
This study will be conducted at La Liga Contra el Cancer in San Pedro Sula, Honduras. The overall objective of this project is to improve symptom management for patients undergoing chemotherapy in Honduras.
- Conditions
- Chemotherapy-induced Neutropenia, Chemotherapy-induced Nausea and Vomiting, Anxiety, Depression
- Trial name
- CLARO (NCT03208816)
- Testing
- symptom management program for chemotherapy patients
- Where
- 2 sites in United States, Honduras
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Leiomyoma
Superior Hypogastric Nerve Block for Pain Control Post-uterine Fibroid Embolization
Uterine fibroid embolization (UFE) is now an accepted treatment of uterine fibroids. However the procedure is often very painful and, in many centres, patients are admitted overnight with patient controlled analgesic (PCA) pumps…
- Trial name
- NCT02270255
- Testing
- Superior hypogastric nerve block, 0.75% Ropivacaine, Subcutaneous injection
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Oropharynx Cancer
Gabapentin for the Reduction of Radiation Therapy Induced Pain During the Treatment of Oropharyngeal Cancer
Strategies to minimize and mitigate external beam radiation therapy related mucositis and pain during the treatment of head and neck cancer remain limited.
- Trial name
- NCT03269344
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Vulvar Cancers, Vulva Neoplasm
Needlefree Lidocaine Application for Vulvar Biopsies
The goal of this study is to compare pain during a vulvar biopsy using either the needle-free J-Tip device or the standard lidocaine shot.
- Conditions
- Vulvar Cancers, Vulva Neoplasm, Vulvar Dysplasia
- Trial name
- NCT07793552
- Testing
- J-Tip, Lidocaine HCl 1%
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Postoperative Pain, Postoperative Complications
Comparison of the Efficacy of Peripheral Nerve Blocks in Major Open Gynaecological Cancer Surgery
The aim of this prospective randomized study was to compare the effectiveness of subcostal transversus abdominis plane block or rectus sheath block applied in addition to posterior transversus abdominis plane block for…
- Conditions
- Postoperative Pain, Postoperative Complications, Analgesia, Regional Anesthesia Morbidity
- Trial name
- NCT06342076
- Testing
- Patients undergoing subcostal transversus abdominis plane block and posterior transversus abdominis plane block, Patients undergoing rectus sheat block and posterior transversus abdominis plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Breast Neoplasm Female, Pain, Postoperative
Effectiveness of Ultrasound Guided PECS Block on Opioid Consumption and Patient Satisfaction Through Adequate Pain Control Following Breast Cancer Surgery.
Breast cancer is the most common and leading cause of cancer deaths among females worldwide. Patients undergoing modified radical mastectomy (MRM) are associated with moderate to severe acute postoperative pain and shoulder…
- Conditions
- Breast Neoplasm Female, Pain, Postoperative, Pain, Analgesia
- Trial name
- NCT04343807
- Testing
- PECS Block, Control Group
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Mastectomy, Mastectomy Patient
A Study on Pain After Breast Reconstruction
The purpose of this study is to find out how common persistent postmastectomy pain (PPMP) is among people who have had a mastectomy and breast reconstruction surgery for their breast cancer.
- Conditions
- Mastectomy, Mastectomy Patient, Mastectomy and Breast Reconstruction, Breast Reconstruction
- Trial name
- NCT06627582
- Testing
- PROMIS Scale v2.0 - Pain Intensity 3a, PROMIS 29+2, PROMIS Scale v2.0 - Nociceptive Pain Quality 5a
- Where
- 7 sites in United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Autoimmune Diseases, Systemic Inflammatory Process
Vitamin D and Fish Oil for Autoimmune Disease, Inflammation and Knee Pain
The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) is a randomized clinical trial in 25,871 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or omega-3 fatty acids (Omacor® fish…
- Conditions
- Autoimmune Diseases, Systemic Inflammatory Process, Knee Pain Chronic, Osteoarthritis
- Trial name
- VITAL (NCT01351805)
- Testing
- Fish Oil, Vitamin D
- Where
- United States
- Volunteers
- 25,871 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Adenomyosis of Uterus
Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms
The goal of this study/research is to assess the relationship between ultrasound features of the myometrium suggestive of adenomyosis and clinical symptoms of adenomyosis and to establish a reporting system for adenomyosis…
- Trial name
- MUSA3 (NCT07397715)
- Where
- 5 sites in Belgium, Poland and 2 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Swiss GO Trial Group
Inferior Turbinate Hypertrophy, Chronic Rhinosinusitis (CRS)
Efficacy of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic Procedures
The purpose of this study is to evaluate the efficacy of lavender aromatherapy in adult patients undergoing awake otolaryngologic procedures in the outpatient clinic setting.
- Conditions
- Inferior Turbinate Hypertrophy, Chronic Rhinosinusitis (CRS), Rhinitis, Vasomotor, Thyroid Nodules
- Trial name
- NCT07299474
- Testing
- Lavender Aromatherapy
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center