Clinical trials: Cancer Patients With Cancer Pain
Breast Cancer Patients With Chronic Pain After Surgery
Effect of Bupivacaine Liposome Anterior Serratus Deep Block on Chronic Pain After Breast Cancer Surgery: a Randomized Controlled Study
This study aims to investigate the effect and influence of liposome bupivacaine anterior serrat plane block on postoperative chronic pain in breast cancer patients, evaluate the therapeutic effect of liposome bupivacaine in…
- Trial name
- NCT06427044
- Testing
- Anterior serratus block group
- Where
- China
- Volunteers
- 143 people
- Sponsor
- Lu Hua
Opioid-Induced Constipation
European Study of Opioid Induced Constipation
Constipation is common (40-90%) in advanced cancer patients , and has a significant negative impact on quality of life. The aetiology of constipation is often multifactorial in advanced cancer patients.
- Trial name
- E-StOIC (NCT05149833)
- Where
- Ireland
- Volunteers
- 1,200 people
- Sponsor
- University of Dublin, Trinity College
Surgery, Breast Cancer
Chronic Pain and Minor Breast Cancer Surgery
Breast cancer is the most frequent in women. Early diagnosis and recent treatments have improved overall mortality. However, chronic pain (pain lasting more than 3 months after surgery) remains a public health problem with impact…
- Conditions
- Surgery, Breast Cancer, Pain, Postoperative, Pain, Chronic
- Trial name
- DCPO Sein (NCT03912948)
- Where
- France
- Volunteers
- 205 people
- Sponsor
- Institut Claudius Regaud
Pain, Cancer
Study to Compare the Safety and Tolerability of Sativex® in Patients With Cancer Related Pain
The purpose of this study is to assess the safety and tolerability of long term therapy with Sativex® and GW-2000-02.
- Trial name
- NCT00675948
- Testing
- Sativex, GW-2000-02
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Jazz Pharmaceuticals
Chronic Pain
Radiofrequency Splanchnic Denervation Versus Retrocrural Neurolytic Celiac Block for Pancreatic Cancer Pain
The investigators will evaluate the analgesic efficacy of radiofrequency splanchnic nerve denervation versus neurolytic retrocrural celiac denervation for patients with abdominal pain due to cancer pancreas
- Trial name
- NCT03886298
- Testing
- radiofrequency splanchnic denervation, retrocrural celiac denervation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Post-operative Pain
Bupivacaine Plus Diclofenac Versus Bupivacaine Alone for Postoperative Pain Relief in Gynecologic Cancer Patients
compare the postoperative pain between Bupivacaine peritoneal Infiltration plus immediately postoperative intramuscular Diclofenac and Bupivacaine peritoneal infiltration alone by using visual analogue score (VAS).
- Trial name
- NCT03796403
- Testing
- Diclofenac
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Breast Cancer
Clinical Trial Comparing Outcomes of Breast Conserving Operations With Classic v High-frequency Electrocoagulation
The aim of this study is to assess the outcomes of breast conserving therapy operation depending on the type of surgical tool used: classic electrocoagulation with higher operative temperatures and high frequency…
- Trial name
- NCT01216254
- Testing
- classic v high-frequency electrocoagulation
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Gdansk
Chronic Pain, Insomnia
The Efficacy of CALPXT96™in Improving Sleep Quality in Patients With Chronic Non-cancer Pain
California Poppy has been traditionally used in Herbal Medicine as an analgesic, mild sedative and/or sleep aid. However there are no human clinical trial data to support its use.
- Trial name
- CALPXT96 (NCT02232256)
- Testing
- CALPXT96
- Where
- Canada
- Sponsor
- 9305-9954 Quebec Inc
Cancer Pain
Intravenous vs Oral Analgesia in Cancer Patients With Severe Pain After Successful Titration
Pain is one of the most common and fear symptoms for cancer patients, which seriously affects the quality of life in cancer patients. At present, oral opioid is the most common route to administrate cancer pain.
- Trial name
- NCT04243954
- Testing
- PCA IV Hydromorphone (continuous dose = 0), PCA IV Hydromorphone (continuous dose ≠ 0), Oral morphine
- Where
- China
- Volunteers
- 95 people
- Sponsor
- Fujian Cancer Hospital
Neoplasms, Bone Tissue, Pain, Intractable
Study of the Impact of the Femoral Implant "Y-strut" on Lytic Bone Metastases of the Femoral Neck (WAZA-ARY)
Bone metastases appear in many cancers. They are associated with severe pain that is refractory to standard treatment. Improving the quality of life and better pain relief is therefore an essential goal of the treatment of…
- Conditions
- Neoplasms, Bone Tissue, Pain, Intractable, Hip Fractures
- Trial name
- WAZA-ARY (NCT03887494)
- Testing
- Implantation
- Volunteers
- 15 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pain, Bone Metastases
Pain Phenotyping of Patients With Bone Cancer Pain
The study aims to describe and quantify pain related to metastatic bone disease. The study will include 50 subjects with disseminated breast cancer and 20 healthy subjects.
- Conditions
- Pain, Bone Metastases, Metastatic Breast Cancer
- Trial name
- BonemetPAIN (NCT03908853)
- Where
- 2 sites in Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Pain, Postoperative
Chronic Pain Following Thoracic Surgery
Pain that persists after the healing of a surgical wound has previously been described as an important, but often unrecognized clinical problem.
- Trial name
- PTPS-18 (NCT01144845)
- Testing
- Thoracic surgery
- Where
- Denmark
- Volunteers
- 702 people
- Sponsor
- University of Aarhus
Advanced Biliary Tract Cancer(BTC), Advanced Pancreatic Cancers
A Prospective Observational Study of First-Line Systemic Therapy Combined With Celiac Plexus Blockade for Advanced Biliopancreatic Cancer With Pain
This study is for patients with advanced bile duct or pancreatic cancer who are experiencing pain from their disease. The purpose of this research is to learn about the effects of combining a standard pain relief treatment…
- Conditions
- Advanced Biliary Tract Cancer(BTC), Advanced Pancreatic Cancers, Cancer-related Pain
- Trial name
- NCT07326137
- Testing
- First-Line Systemic Therapy, Celiac Plexus Neurolysis (CPN)
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Tongji Hospital
Pain, Cancer
A Dose-Finding Study of Fentanyl (JNS020 QD) 1-Day Transdermal Patch in Participants With Cancer Pain
The purpose of this study is to evaluate the efficacy and safety of fentanyl 1-day application (JNS020QD) transdermal patch (patch containing a drug that is put on the skin so the drug can enter the body through the skin) and to…
- Trial name
- NCT00644787
- Testing
- Fentanyl 1-day transdermal patch (Titration Phase), Fentanyl 1-day transdermal patch (Double Blind Phase), Fentanyl 3-day transdermal patch (Double Blind Phase)
- Where
- 43 sites in Japan
- Volunteers
- 156 people
- Sponsor
- Janssen Pharmaceutical K.K.
Cancer Pain, Renal Insufficiency Chronic
Assessing Hydromorphone Sustained-Release Tablets in Elderly Cancer Pain Patients With Renal Insufficiency
This clinical study aims to understand whether domestic hydromorphinone sustained-release tablets are effective and safe in treating moderate to severe cancer pain in elderly patients with renal insufficiency.
- Conditions
- Cancer Pain, Renal Insufficiency Chronic, Hydromorphone Use
- Trial name
- NCT07421674
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Taian Cancer Hospital
Head and Neck Carcinoma, Hypopharyngeal Carcinoma
Intraoperative Methadone for the Management of Postoperative Pain in Patients With Head and Neck Cancers
This phase IV trial compares how well methadone plus standard fentanyl given during surgery (intraoperative) works compared to intraoperative standard fentanyl alone in managing pain after surgery (postoperative) among patients…
- Conditions
- Head and Neck Carcinoma, Hypopharyngeal Carcinoma, Laryngeal Carcinoma, Oral Cavity Carcinoma
- Trial name
- NCT07857655
- Testing
- Electronic Health Record Review, Fentanyl, Laryngoscopy
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- OHSU Knight Cancer Institute
Pre- and Postoperative Analgesia, Spinal Anesthesia
Randomized Study of Spinal Anesthesia Compared With Traditional Epidural Anesthesia Concerning Peroperative and Postoperative Pain After Open Nephrectomy in Patients With Renal Cell Carcinoma
The study aim to study whether spinal anesthesia (using: bupivacain, morfin och klonidin) can be better than epidural anesthesia during and after open surgery for renal cell carcinoma.
- Conditions
- Pre- and Postoperative Analgesia, Spinal Anesthesia, Renal Cell Carcinoma
- Trial name
- ASA (NCT02030717)
- Testing
- klonidin, epidural anesthesia
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Umeå University
Neuropathic Pain
Clinical Trial Assessing the Efficacy of Capsaicin Patch (Qutenza®) in Cancer Patients With Neuropathic Pain
In the oncology area, neuropathic pains are relatively frequent and can be induced by surgery, radiotherapy, or chemotherapy. In usual practice, some units are using qutenza in order to reduce neuropathic pain even though using…
- Trial name
- CAPSONCO (NCT03317613)
- Testing
- Qutenza
- Where
- 3 sites in France
- Volunteers
- 84 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Neurotoxicity, Pain
Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
RATIONALE: Lamotrigine may be effective in reducing pain, numbness, tingling, and other symptoms of peripheral neuropathy. It is not yet known whether lamotrigine is effective in treating peripheral neuropathy caused by…
- Conditions
- Neurotoxicity, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00068445
- Testing
- lamotrigine
- Where
- 23 sites in United States
- Volunteers
- 131 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Chemotherapy Effect, Pain Cancer
Effects of Virtual Museum Visit on Pain, Fatigue, and Anxiety in Patients Receiving Chemotherapy
Symptom management is the most important aspect of clinical cancer care. Virtual reality-based interventions can be used to improve cancer patients' experiences with medical treatment, with their distraction-based effects.
- Conditions
- Chemotherapy Effect, Pain Cancer, Fatigue, Anxiety
- Trial name
- NCT06844695
- Testing
- Art Therapy (Virtual Museum Visit)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University