Clinical trials: Cancer Patients and Physical Activity
Neoplams, PIV Catheter Insertion
The Effect of Isometric Exercise and Dry Heat Application on PIVC
Purpose: This study was conducted to evaluate the effect of isometric exercise and dry heat application technique on venous fullness and vein visibility in cancer patients.
- Trial name
- NCT07704502
- Testing
- Isometric exercise, Dry heat application
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Inonu University
Prostate Cancer, Metastases
A Research Study for Patients With Prostate Cancer
The purpose of this study is to evaluate the activity of romidepsin (depsipeptide,FK228) in patients with metastatic prostate cancer who have developed a rising prostate specific antigen (PSA) while undergoing hormonal therapy.
- Trial name
- NCT00106418
- Testing
- Romidepsin
- Volunteers
- 35 people
- Sponsor
- Celgene
Low Anterior Resection Syndrome
Paula Method of Exercises in Patients With LARS Syndrome:Randomized Controlled Trial
Sphincter sparing rectal resection surgery, either total mesorectal excision (TME) with a temporary loop ileostomy or partial mesorectal excision (PME), is the mainstay of rectal cancer treatment , however, these treatments are…
- Trial name
- NCT05682157
- Testing
- Paula Method of muscle exercises
- Where
- 2 sites in Israel
- Volunteers
- 62 people
- Sponsor
- Hadassah Medical Organization
Chronic Lymphocytic Leukemia (CLL), Lymphoma, Non-Hodgkin (NHL)
Dose Escalation Study of CAL-101 in Select Relapsed or Refractory Hematologic Malignancies
The purpose of this study is to determine the dose that can be safely given to see what effect it may have on your cancer and to determine how the drug is distributed in the body.
- Conditions
- Chronic Lymphocytic Leukemia (CLL), Lymphoma, Non-Hodgkin (NHL), Acute Myeloid Leukemia (AML), Multiple Myeloma (MM)
- Trial name
- NCT00710528
- Testing
- CAL-101
- Where
- 9 sites in United States
- Volunteers
- 192 people
- Sponsor
- Gilead Sciences
Advanced Gastrointestinal Cancer
Physical Function and Activities of Daily Living in Cancer Patients During Chemotherapy
The study is a randomized controlled trial with the aim to examine the feasibility and the effects of a home-based exercise intervention program on activities of daily living (ADL) in patients with advanced gastrointestinal…
- Trial name
- NCT02677129
- Testing
- home-based exercise intervention
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Goethe University
Breast Cancer, Cancer Related Fatigue
Feasibility of 'Exercise for CAncer Patients and Healthy EAting Timeframes' .
This study evaluates the feasibility and preliminary effects of a home based exercise and activity program for individuals with cancer.
- Trial name
- EXCAP-hEAT (NCT07529353)
- Testing
- EXCAP Exercise Program, 10-Hour Healthy Eating Timeframe (hEAT)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Rochester
Breast Cancer
An Exercise Intervention for Breast Cancer Patients: Feasibility and Effectiveness (BEAT Cancer Trial; Pilot Study)
"Translation" of the current "basic science" information related to physical activity into patient intervention programs is needed. This translation is critical to providing benefit to the maximum number of patients.
- Trial name
- BEAT (NCT00721565)
- Testing
- Exercise Behavior Change
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Alabama at Birmingham
Cancer Survivors
C.A.P.A.B.L.E. (CrossFit® and Physical Activity: A Better Life Experience)
This study will introduce cancer survivors to cross-training with the expectation that the program proposed will ultimately result in superior improvements in functional performance, body composition and quality of life compared…
- Trial name
- CAPABLE (NCT03750981)
- Testing
- 12 week pilot intervention study.
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Neoplasms, Venous Thromboembolism
Anti Xa Activity in Cancer Patients Receiving Low-molecular-weight Heparin for Venous Thromboembolism
Low molecular weight heparins (LMWH) are the reference molecule for the long term treatment of venous thromboembolism (VTE) in cancer patients but remains, however, associated with a high risk of recurrent thromboembolism.
- Trial name
- aXa (NCT02898051)
- Where
- 8 sites in France
- Volunteers
- 370 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Renal Cancer Cell
Third Line TKI After 2 TKIs in Patients With mRCC (Tokio Study)
The study aims to evaluate the efficacy of a third TKI after two previous lines of therapy with TKIs, in terms of median progression free survival (mPFS), in patients affected by metastatic renal cancer cell.
- Trial name
- TOKIO (NCT03456401)
- Testing
- Sorafenib or Sunitinib
- Where
- Italy
- Volunteers
- 18 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Brain Tumor, Vascular Lesion
Factor XIII and Pulmonary Embolism in Neurosurgical Patients
Two studies (Gerlach et al. 2000; Gerlach et al. 2002) described the impact of factor XIII on the risk of prospective hemorrhage for patients undergoing craniotomy.
- Conditions
- Brain Tumor, Vascular Lesion, Factor XIII Deficiency, Pulmonary Embolism
- Trial name
- NCT01106937
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Advanced Solid Tumors
Evaluation of the Safety and Efficacy of Albumin-bound Docetaxel
This trial is an open-label, single-center, dose-escalation and cohort-expansion Phase I clinical study in patients with advanced solid tumors.
- Trial name
- NCT04471675
- Testing
- Albumin-bound docetaxel
- Where
- China
- Volunteers
- 208 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Cysticercosis, Cysts
Brain Tissue Swelling and Seizure Activity in Inactive Cysticercosis
This study will examine what causes seizures in patients with cysticercosis (pork tapeworm infection). A better understanding of this could lead to improved methods of controlling or preventing seizures.
- Conditions
- Cysticercosis, Cysts, Seizures
- Trial name
- NCT00001912
- Where
- 2 sites in United States, Peru
- Volunteers
- 6 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pediatric Cancer Patients
Evaluation of an Exercise Intervention During Intensive Medical Treatment in Pediatric Oncology.
The BEPPO study is a Germany-wide clinical trial investigating whether a structured exercise program can improve physical and mental health in children and adolescents undergoing cancer treatment.
- Trial name
- BEPPO (NCT07647471)
- Testing
- Partially-standardised, supervised, continuity-of-care exercise intervention
- Where
- 13 sites in Germany
- Volunteers
- 346 people
- Sponsor
- Universität Duisburg-Essen
Carcinoma, Endometrial Adenocarcinoma
PEN-866 in Patients With Advanced Solid Malignancies
Protocol PEN-866-001 is an open-label, multi-center, first-in-human Phase 1/2a study evaluating PEN-866 in patients with advanced solid malignancies whose disease has progressed after treatment with previous anticancer therapies.
- Conditions
- Carcinoma, Endometrial Adenocarcinoma, Neoplasms, Squamous Cell Carcinoma of the Anus
- Trial name
- NCT03221400
- Testing
- PEN-866 Sodium, fluorouracil, Folinic acid
- Where
- 16 sites in United States
- Volunteers
- 340 people
- Sponsor
- Tarveda Therapeutics
Breast Cancer, Colon Cancer
The Efficacy of Health Partnership Program for Cancer Patients
The Objectives of this study is 1. To evaluate the efficacy for exercise, diet, and posttraumatic growth as a result of participating in tailored program (Health Partnership Program) for 24 weeks 2.
- Conditions
- Breast Cancer, Colon Cancer, Gastric Cancer, Lung Cancer
- Trial name
- NCT01527409
- Testing
- Tailored health partnership program, Usual care and health education workshop
- Where
- 10 sites in South Korea
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Colon Cancer
Impact of Exercise and Hyperlipidic Meal on Free Circulating DNA in Patients With Metastatic Colonic Cancer and Healthy Subjects
The study of circulating tumoral DNA makes it possible to study, without invasive procedures or pathological studies, the tumoral DNA circulating in the blood of a patient and its various alterations.
- Trial name
- ASRHACOLS (NCT05147545)
- Testing
- Moderate intensity physical effort, Low intensity physical effort, Hyperlipidic meal
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Advanced Solid Tumors
Study of SIM0508 Alone and in Combination in Patients With Advanced Solid Tumors
This is a multicenter, open-label, first-in-human study to evaluate the safety,efficacy, and PK/PD characteristics of SIM0508 as a single agent and in combination with olaparib in participants with locally advanced/metastatic…
- Trial name
- NCT06686745
- Testing
- SIM0508 Tablets, SIM0508 in combination with olaparib
- Where
- 2 sites in China
- Volunteers
- 130 people
- Sponsor
- Jiangsu Simcere Pharmaceutical Co., Ltd.
Cancer, Chemotherapy-induced Peripheral Neuropathy (CIPN)
Electroacupuncture and Exercise for Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of cancer treatment that causes numbness, pain, and balance issues in a patient's hands and feet.
- Trial name
- EA-EX CIPN (NCT07700901)
- Testing
- Electroacupuncture, Exercise Training, Structured Home-Based Health Education and Dose-Controlled Exercise Program
- Where
- 2 sites in Taiwan
- Volunteers
- 82 people
- Sponsor
- Show Chwan Memorial Hospital
Breast Cancer, Advanced Solid Tumor
An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BG-75202 (KAT6A/B inhibitor) alone and in combination with other therapies in…
- Trial name
- NCT07222267
- Testing
- BG-75202, CDK4 Inhibitor, Estrogen Receptor Antagonist
- Where
- 32 sites in United States, Australia and 4 more
- Volunteers
- 86 people
- Sponsor
- BeOne Medicines