Clinical trials: Cancer Patients and Physical Activity
Breast Cancer
Studying Tailored Exercise Prescriptions in Breast Cancer Patients
Chemotherapy forms a significant part of many breast cancer patient's treatment and is associated with various common, known adverse effects.
- Trial name
- STEPS (NCT02802826)
- Testing
- Tailored Exercise Prescription
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Loughborough University
Ovary Cancer, Endometrial Cancer
Physical Activity Intervention Among Older Women With Gynecologic Cancers (Fit4Treatment)
The primary purpose of the study is to determine which of four components (symptom-burden tailored app, exercise partner, oncology provider engagement, coaching) added to a core intervention of a wearable activity tracker and…
- Conditions
- Ovary Cancer, Endometrial Cancer, Uterine Cancer, Cervical Cancer
- Trial name
- NCT05743517
- Testing
- Fit4Treatment
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Northwestern University
Breast Cancer
Digital Phenotyping in Young Breast Cancer Patients Treated With Neoadjuvant Chemotherapy
NeoFit is a prospective, national, multicenter, single-arm open-label study. It will include a total of 300 participants under the age of 70 years treated with neoadjuvant chemotherapy for BC.
- Trial name
- NeoFit (NCT05011721)
- Testing
- Activity tracker
- Where
- 3 sites in France
- Volunteers
- 300 people
- Sponsor
- Institut Curie
Physical Activity, Patient
The Relationships Between Physical Activity Level, Quality of Life and Cognitive Level in Breast Cancer Patients
The aim of this study is to determine the relationships between physical activity level, quality of life and cognitive level in patients with breast cancer and to compare the results with a population of similar age group.
- Conditions
- Physical Activity, Patient, Quality of Life, Chemotherapy
- Trial name
- NCT05275517
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Acute Myeloid Leukaemia
Phase I/II Trial of S64315 Plus Azacitidine in Acute Myeloid Leukaemia
The purpose of this study is to assess the safety, tolerability and clinical activity of the combination S64315 with azacitidine in patients with acute myeloid leukaemia.
- Trial name
- NCT04629443
- Testing
- S 64315 (also referred as MIK665) and azacitidine
- Where
- 7 sites in United States, Australia and 2 more
- Volunteers
- 17 people
- Sponsor
- Institut de Recherches Internationales Servier
Solid Tumor, Neoplasms
Intratumoral Chlorine Dioxide Injection in Advanced Solid Tumors
The purpose of this study is to evaluate the safety of injecting a 2% chlorine dioxide solution directly into tumors in adults with advanced solid tumors, and to determine whether the injected solution stays within the tumor…
- Trial name
- NCT07911293
- Testing
- Chlorine Dioxide Injection 2%
- Volunteers
- 50 people
- Sponsor
- SunGlow Innovations LLC
Neuropathic
Pulsed Electromagnetic Field Therapy to a Tailored Exercise Program for Patients Suffering From Chemotherapy-induced Neuropathy Related to Breast Cancer
This research studied the usefulness of a targeted intervention designed to manage chemotherapy-induced symptoms, particularly focusing on pain relief, balance deviations and functional improvements.
- Trial name
- PEMFTEPCHIN (NCT06947577)
- Testing
- pulsed electromagnetic field (PEMF) therapy and a tailored exercise program (TEP), Tailored Exercise Program
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Postoperative Pain, Nursing Caries
Effect of Progressive Relaxation Exercise on Physiological Parameters, Pain, Anxiety in Colorectal Cancer Surgery
This research was carried out as an pre-test/post-test control group experimental design study in order to determine the effect of progressive relaxation exercises on the level of vital sign, pain and anxiety underwent who…
- Conditions
- Postoperative Pain, Nursing Caries, Anxiety
- Trial name
- NCT04731428
- Testing
- Progressive Relaxation Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- YASEMİN ÖZHANLI
Melanoma
A Study of Safety and Clinical Activity of Immunotherapy Plus Chemotherapy in Metastatic Melanoma Patients
The purpose of this clinical trial is to find out how successfully, patients with progressive metastatic cutaneous melanoma, are able to develop an immune response to injections with the immunotherapeutic product GSK1572932A when…
- Trial name
- NCT00849875
- Testing
- Immunotherapeutic GSK2132231A, Dacarbazine
- Where
- 14 sites in Belgium, France
- Volunteers
- 48 people
- Sponsor
- GlaxoSmithKline
Cancer, Cancer, Lung
A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors
The goal of this clinical trial is to test CPO301, a type of drug called an antibody drug conjugate in adult patients with advanced or metastatic solid tumors.
- Trial name
- NCT05948865
- Testing
- CPO301
- Where
- 14 sites in United States, Canada
- Volunteers
- 132 people
- Sponsor
- Conjupro Biotherapeutics, Inc.
Advanced Solid Tumors
A Study of CSPCHA131 in Patients With Advanced Solid Tumor
The study was designed to evaluate the safety, tolerability, pharmacokinetics, and preliminary antitumor activity of CSPCHA131 alone or plus chemotherapy in patients with advanced solid tumors.
- Trial name
- NCT04325711
- Testing
- CSPCHA131
- Where
- China
- Volunteers
- 100 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Hepatocellular Carcinoma, Insulin Resistance
The Effect of Mobile Health-based Exercise on Hepatocellular Carcinoma Patients With Insulin Resistance
Exercise is predicted to have positive effect among patients with hepatocellular carcinoma (HCC). However, little attention has been paid to the role of physical activity with wearable device in the management of HCC patients in…
- Trial name
- NCT04649671
- Testing
- Mobile health
- Where
- South Korea
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Non-muscle Invasive Bladder Cancer
CAVATAK (CVA21) in Non-muscle Invasive Bladder Cancer (VLA-012 CANON)
The study consisted of 2 sequential parts. Part A assessed the safety and tolerability of CAVATAK administered via intravesical instillation in patients with non-muscle invasive bladder cancer scheduled to undergo TUR.
- Trial name
- CANON (NCT02316171)
- Testing
- CVA21, Mitomycin C
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Viralytics
Solid Tumor, Adult
Study of DF1001 in Patients With Advanced Solid Tumors
DF1001-001 is a study of a new molecule that targets natural killer (NK) cells and T-cell activation signals to specific receptors on cancer cells. The study will occur in two phases.
- Trial name
- NCT04143711
- Testing
- DF1001, Nivolumab, Nab paclitaxel
- Where
- 44 sites in United States, Belgium and 4 more
- Volunteers
- 270 people
- Sponsor
- Dragonfly Therapeutics
Pancreatic Neoplasms
Evaluation of Killing Activity of Expanded Natural Killer Cells From Blood in Patients With Pancreatic Cancer
Pancreatic cancer, one of the deadliest epithelial malignancies, has a 5-year survival rate of only about 8%. The mortality rate has decreased slightly, but the incidence rate has been steadily increasing, and it is predicted to…
- Trial name
- NCT03665571
- Testing
- Receptor specific activation method
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Advanced Solid Tumor
A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors
This study investigates the safety and tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of EIK1003 in participants with advanced solid tumors.
- Trial name
- NCT06253130
- Testing
- IMP1734
- Where
- 57 sites in United States, Australia and 6 more
- Volunteers
- 156 people
- Sponsor
- Eikon Therapeutics
Melanoma (Skin Cancer), Melanoma Stage IIIB-IV
A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma
The goal of this clinical trial is to understand if a new drug called LNS8801 can safely treat patients with melanoma. The primary question to be answered is what is the average length of time during which melanoma does not grow…
- Conditions
- Melanoma (Skin Cancer), Melanoma Stage IIIB-IV, Cutaneous Melanoma, Unresectable Melanoma
- Trial name
- NCT06624644
- Testing
- LNS8801, Pembrolizumab, Chemotherapy (dacarbazine or temozolomide)
- Where
- 9 sites in United States
- Volunteers
- 135 people
- Sponsor
- Linnaeus Therapeutics, Inc.
Solid Tumors
A Study of Selicrelumab (RO7009789) in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
This is an open-label, multicenter study designed to assess the safety, pharmacokinetics, pharmacodynamics and activity of Selicrelumab administered in combination with Atezolizumab (ATZ) in participants with metastatic or…
- Trial name
- NCT02304393
- Testing
- Atezolizumab, Selicrelumab
- Where
- 11 sites in United States, Canada and 4 more
- Volunteers
- 140 people
- Sponsor
- Hoffmann-La Roche
Primary Liver Cancer, Secondary Liver Cancer
Preoperative Physical Activity Intervention in Patients Before Planned Liver Resection for Cancer (APACHE)
The aim of this study is to assess the impact of preoperative physical activity on physical capacities of patients undergoing liver resection for primary or secondary liver cancer.
- Conditions
- Primary Liver Cancer, Secondary Liver Cancer, Liver Metastases
- Trial name
- APACHE (NCT03518632)
- Testing
- Interval training, Standard Oncologic care
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Célia Turco
Menopausal Symptoms in Breast Cancer Patients With Treatment-Induced Complaints
Cognitive Behavioral Therapy (CBT) and Physical Exercise for Climacteric Symptoms in Breast Cancer Patients Experiencing Treatment-Induced Menopause: a Multicenter Randomized Trial
Background: Breast cancer is the most common form of cancer among women in the Netherlands. Approximately 11,000 women are diagnosed with breast cancer annually, of whom about 30% are below 50 years of age.
- Trial name
- EVA project (NCT00582244)
- Testing
- CBT and relaxation, Physical activity, CBT and physical activity
- Volunteers
- 325 people
- Sponsor
- The Netherlands Cancer Institute
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