Clinical trials: Cancer Patients and Physical Activity
Stage I Endometrial Adenocarcinoma, Uterine Cancer
Assisted Exercise in Obese Endometrial Cancer Patients
This is an assisted exercise trial involving exercise on a stationary bike, brain imaging and DNA(genetics)sampling. The purpose of this study is to find out if performing a progressive, supervised assisted exercise program on a…
- Conditions
- Stage I Endometrial Adenocarcinoma, Uterine Cancer, Obesity
- Trial name
- NCT01870947
- Testing
- Exercise on stationary recumbent exercise cycle, Health Education, Questionnaires
- Where
- 2 sites in United States
- Volunteers
- 95 people
- Sponsor
- Case Comprehensive Cancer Center
Cancer Colorectal, Hypnosis, Animal
Representations, Beliefs and Attitudes Towards Hypnosis in Patients Followed for Colorectal Cancer
Over the past decade, changes in knowledge and attitudes toward complementary and alternative medicine have been occurring. One study shows that 21% of patients are turning to them. In contrast, hypnosis is among the least used.
- Trial name
- NCT05791747
- Testing
- semi-structured interviews
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University of Nimes
Breast Cancer
Consequences of Eccentric Cycling on Exercise-related Neuromuscular Responses and Biomarkers in Breast Cancer Patients
This is a monocentric, prospective and interventional study aimed to investigating the physiological responses of eccentric compared to concentric cycling realized 1) at the same metabolic demand and 2) at the same mechanical…
- Trial name
- PROTECT-05 (NCT05166148)
- Testing
- Session (a), Session (b), Session (c)
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Institut de cancérologie Strasbourg Europe
Metastatic Pancreatic Cancer, Colorectal Cancer
A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and Other Advanced Solid Tumors
The purpose of this study is to confirm the safety and tolerability of TAK-931 in a cohort of Western participants with metastatic solid tumors and to evaluate the anti-tumor activity of TAK-931 in participants with metastatic…
- Conditions
- Metastatic Pancreatic Cancer, Colorectal Cancer, Esophageal Neoplasms, Carcinoma, Non-small-cell Lung
- Trial name
- NCT03261947
- Testing
- TAK-931
- Where
- 10 sites in United States, Japan
- Volunteers
- 101 people
- Sponsor
- Millennium Pharmaceuticals, Inc.
Head and Neck Neoplasm, Radiotherapy
Feasibility and Safety of Aerobic Exercise for Head and Neck Cancer Patients
Treated head and neck cancer patients are subject to tissue swelling and scarring, known as lymphedema and fibrosis (LEF). LEF in the head and neck cancer patient occurs in up to 90% of treated patients and is associated with…
- Trial name
- NCT04679233
- Testing
- Prescription aerobic exercise
- Where
- United States
- Sponsor
- Vanderbilt University
Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory
An Adaptive Open-label Multicentre Phase 1/2 Trial, to Determine the Recommended Phase 2 Dose of CCTx-001, and to Assess Safety, Tolerability, and Clinical Activity in Patients With Relapsed/Refractory Acute Myeloid Leukaemia
The purpose of this adaptive Phase 1/2 study is to evaluate the safety, tolerability, pharmacokinetics (PK), and antileukemic activity of CCTx-001 in adult patients with r/r Acute Myeloid Leukemia (AML).
- Trial name
- RESOLVE AML001 (NCT06281847)
- Testing
- CCTx-001
- Where
- 6 sites in France, Germany and 2 more
- Volunteers
- 143 people
- Sponsor
- Advesya SAS
Breast Cancer, Depression
Physical Activity or Usual Care in Preventing Weight Gain in Women With Stage I or Stage II Breast Cancer Undergoing Chemotherapy
RATIONALE: Physical activity may prevent or reduce weight gain in women receiving chemotherapy for early stage breast cancer. PURPOSE: This randomized phase I/II trial is studying physical activity to see how well it works…
- Conditions
- Breast Cancer, Depression, Fatigue, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- NCT00509626
- Testing
- exercise intervention, questionnaire administration, CAM exercise therapy
- Where
- United States
- Volunteers
- 380 people
- Sponsor
- Fox Chase Cancer Center
Locally Advanced Breast Cancer (LABC), Postoperative Inflammation
Preoperative Shoulder Exercises and Postoperative Inflammation, Pain, and Function After Modified Radical Mastectomy
This study evaluates whether preoperative shoulder range-of-motion exercises influence postoperative inflammatory response, pain, shoulder function, and quality of life in patients with locally advanced breast cancer undergoing…
- Conditions
- Locally Advanced Breast Cancer (LABC), Postoperative Inflammation, Prehabilitation
- Trial name
- NCT07420335
- Testing
- Preoperative shoulder exercise, Standard preoperative care
- Where
- Indonesia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Multiple Myeloma
Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma
Multiple myeloma (MM) is a plasma cell disease characterized by the growth of clonal plasma cells in the bone marrow. The purpose of this study is to assess the adverse events and change in disease activity of etentamig in…
- Trial name
- NCT06896916
- Testing
- Etentamig, Iberdomide
- Where
- 27 sites in United States, Australia and 5 more
- Volunteers
- 135 people
- Sponsor
- AbbVie
Breast Cancer, Prostate Cancer
Home Based Exercise for Patients With Breast or Prostate Cancer (The BENEFIT-CA Study)
The purpose of this trial is to evaluate the feasibility of a home based exercise program for individuals with breast or prostate cancer patients undergoing active treatment.
- Trial name
- BENEFIT-CA (NCT05258526)
- Testing
- Home based exercise training
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Multiple Myeloma
A Study Evaluating Safety, Tolerability and Clinical Activity of FHND6091 in Patients With Multiple Myeloma
This is a phase I, first in human, single arm, open label study that will assess safety, tolerability and clinical activity of FHND6091 when taken orally on a weekly dosing schedule by patients with relapsed and refractory…
- Trial name
- NCT05271682
- Testing
- FHND6091
- Where
- 6 sites in China
- Volunteers
- 40 people
- Sponsor
- Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd.
Malignant Melanoma
Study of the Tumor Saturation and Biological Activity of MEDI-522 (Abergrin) in Patients With Advanced Malignant Melanoma
To describe the tumor tissue saturation by MEDI-522 in patients with advanced malignant melanoma.
- Trial name
- NCT00111696
- Testing
- MEDI-522
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- MedImmune LLC
Sleep Disorder, Breast Cancer
Sleep and Activity Patterns in Pre-menopausal Breast Cancer Patients on Tamoxifen Using a Wrist-worn Internet of Things Device
The aim of this study is to observe the sleep and activity patterns of pre-menopausal breast cancer patients taking tamoxifen using a wrist-worn internet of things device and questionnaires.
- Trial name
- NCT04116827
- Testing
- Tamoxifen Oral Tablet
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Advanced Solid Tumors
A Study of SIGX1094R in Patients With Advanced Solid Tumors
This is a phase I clinical, first-in-human study of SIGX1094R monotherapy. The goal of this trial is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), anti-tumor activity and food effect of…
- Trial name
- NCT06739291
- Testing
- SIGX1094R
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Signet Therapeutics
Renal Cell Cancer
Temsirolimus-RCC-imaging
This study uses one trialdrug: Temsirolimus (sometimes called Torisel ® ). Temsirolimus is an mTOR inhibitor. It is an agent that is specifically aimed at disrupting cell division (needed for cancer cell growth).
- Trial name
- NCT01246817
- Testing
- Temsirolimus
- Where
- Netherlands
- Volunteers
- 51 people
- Sponsor
- Radboud University Medical Center
Advanced Solid Tumors
The Safety and Pharmacokinetics Preliminary Efficacy of IMP7068 in Patients With Advanced Solid Tumors
A Phase 1 Dose Escalation and Expansion Study of IMP7068 Monotherapy in Advanced Solid Tumors
- Trial name
- WEE1 (NCT04768868)
- Testing
- IMP7068
- Where
- 16 sites in United States, China and 1 more
- Volunteers
- 350 people
- Sponsor
- Impact Therapeutics, Inc.
Multiple Myeloma (MM)
Benefits of a 6-month, Individualized, Hybrid, "Real-life" Adapted Physical Activity Program on the Quality of Life of Patients Treated for Multiple Myeloma
The goal of this clinical trial is to evaluate the effect of a long-term, individualized, hybrid adapted physical activity program on the quality of life of patients with multiple myeloma.
- Trial name
- BAPAMM (NCT07547007)
- Testing
- Adapted physical activity
- Where
- 2 sites in France
- Volunteers
- 86 people
- Sponsor
- Centre Hospitalier Metropole Savoie
Breast Cancer
Study of Effects of Dao-yin Exercise on the Patients With Breast Cancer Post Operation and Receiving Adjuvant Chemotherapy
This is a retrospective registration of a study that evaluated whether a traditional Dao-yin (mind-body exercise), called Shangshou Dao-yin, could improve sleep quality, Chinese medicine body constitution, and quality of life in…
- Trial name
- NCT07262099
- Testing
- Shangshou Dao-yin
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Melanoma BRAF V600E/K Mutated, Melanoma and Brain Metastases
Encorafenib and biNimetinib Followed by CEmiplimab and FiAnLimab in Patients With BRAF Mutant melanOma and Symptomatic Brain Metastases
Brain metastases in patients with advanced and metastatic melanoma are a frequent complication and a significant cause of morbidity and mortality in this patient population.
- Trial name
- ENCEFALO (NCT06887088)
- Testing
- Encorafenib + Binimetinib, cemiplimab+fianlimab
- Where
- 18 sites in Spain
- Volunteers
- 33 people
- Sponsor
- Grupo Español Multidisciplinar de Melanoma
Head and Neck Neoplasms
Exercise Prehabilitation in Patients With Head and Neck Squamous-cell Carcinoma: The FIT4TREAT Trial
The main purpose of this randomized-controlled trial is to evaluate the effects of prehabilitation based on exercise training (ET) on functional capacity in HNC patients treated with chemoradiotherapy (CRT).
- Trial name
- FIT4TREAT (NCT05418842)
- Testing
- Prehabilitation
- Where
- 5 sites in Portugal
- Volunteers
- 47 people
- Sponsor
- Associacao de Investigacao de Cuidados de Suporte em Oncologia
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