Clinical trials: Cancer of Colon
Colonoscopy, Colorectal Cancer Screening
Robotic Colonoscopy Using the Triton 4.0 System in Adults for Screening, Surveillance, and Diagnosis of Lower Gastrointestinal Conditions
This study is a prospective, single-arm, non-randomized, single site first-in-human study and will be conducted in two phases, where Phase A will serve to evaluate the safety of the Triton 4.0 System to perform screening…
- Conditions
- Colonoscopy, Colorectal Cancer Screening, Colorectal Neoplasms, Gastrointestinal Endoscopy
- Trial name
- CARE I (NCT06935734)
- Testing
- Diagnostic Colonoscopy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Neptune Medical
Colorectal Neoplasms, Intestinal Neoplasms
Usefulness of GI-GENIUS in FIT-based Colorectal Cancer Screening Program.
Deep learning technology has an increasing role in medical image applications and, recently, an artificial intelligence device has been developed and commercialized by Medtronic for identification of polyps during colonoscopy…
- Conditions
- Colorectal Neoplasms, Intestinal Neoplasms, Gastrointestinal Neoplasms, Colonic Polyp
- Trial name
- CADILLAC (NCT04673136)
- Testing
- GI-GENIUS Medtronic, Colonoscopy
- Where
- 6 sites in Spain
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- Asociación Española de Gastroenterología
Colorectal Cancer
Effectiveness of Tel and SMS Reminder on Compliance With CRC Screening
Colorectal cancer (CRC) is one of the major global health challenges. CRC is currently the third most common cancer in men and the second common in women worldwide, accounting for approximately 10% of all cancers.
- Trial name
- NCT02815436
- Testing
- Telephone reminder, SMS reminder
- Where
- Hong Kong
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal Neoplasms
Serum Proteomic Profiling for the Early Diagnosis of Colorectal Cancer
No ideal serum biomarker currently exists for the early diagnosis of colorectal cancer (CRC). Therefore, it is urgent that accurate and reliable serum biomarkers be identified.
- Trial name
- NCT01604798
- Testing
- Serum proteomics
- Where
- China
- Volunteers
- 547 people, healthy volunteers welcome
- Sponsor
- Fudan University
Patient Preference
Tradeoffs in Patient Decision Making About Rectal Cancer Treatment: Benefits Compared to Quality Of Life.
This study is aiming to look into patients' treatment preferences and their socio economic background as well as the exploration of thought processes leading to these preferences.
- Trial name
- Pathos (NCT04925154)
- Testing
- The only intervention will be the information brochure that will be given after the first questionnaire.
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Colonic Carcinoma, Laparoscopic Right Hemicolectomy
Standardizing Right Hemicolectomy for Colon Cancer
A surgical intervention might be highly variable amongst surgeons and centers. This variability has a potential relevance concerning clinical outcomes.
- Conditions
- Colonic Carcinoma, Laparoscopic Right Hemicolectomy, Standardisation, Training
- Trial name
- Right (NCT04889456)
- Testing
- Implementation standardised laparoscopic right hemicolectomy with proctoring, Implementation standardised laparoscopic right hemicolectomy without proctoring
- Where
- Netherlands
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Colon Cancer
Role of the Spouse/Partner of Persons Treated With Chemotherapy for Colon Cancer
Altered quality of life in patients with stage III or IV colon cancer is well known. At their sides, their spouse/partner must also cope with the suffering caused by the disease and the upheavals that it engenders, with the…
- Trial name
- APPACH (NCT02873845)
- Testing
- Preliminary validation of the COBQoL questionnaire
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Cancer, Breast Cancer
Improving Survivorship Among Minority Cancer Dyads
This proposed intervention centers on improving survivorship outcomes among African American and Latinx cancer survivor and caregiver dyads. As a result, there will be four major outcomes.
- Conditions
- Cancer, Breast Cancer, Colon Cancer, Caregiver Burnout
- Trial name
- NCT04685551
- Testing
- Change in knowledge, motivation, skills, and resources
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Colon Cancer
Pharmacodynamic and Clinical Evaluation of Dose and Taste-optimised Low Volume PEG-based Bowel Cleansing Solutions Using the Split-dosing Intake Regimen in Healthy Subjects and in Subjects Undergoing Screening Colonoscopy
A study to assess the pharmacodynamics, safety and tolerability of a PEG-based bowel cleansing solution (MOVIPREP®)
- Trial name
- NCT01714466
- Testing
- NER1006, MOVIPREP
- Where
- 2 sites in Germany
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Norgine
Colorectal Cancer
Point of Care Test to Diagnosed Colorectal Cancer and Polyps in Low Middle Income Countries
This is a-two phase study. Phase 1 will adapt a 3-metabolite biosensor that identifies patients with colorectal cancer (CRC) and precancerous polyps to Nigerian patients.
- Trial name
- NCT03173729
- Testing
- Biosensor Point of Care Device
- Where
- 5 sites in Nigeria
- Volunteers
- 926 people, healthy volunteers welcome
- Sponsor
- Obafemi Awolowo University Teaching Hospital
Colorectal Neoplasms, Colorectal Cancer
Screening for Colorectal Cancer in Average and High Risk Population
The existing evidence from epidemiological studies and randomized controlled trials has consistently assures the cost effectiveness and the influential role of screening in reducing incidence rates and deaths caused by Colorectal…
- Conditions
- Colorectal Neoplasms, Colorectal Cancer, Adenomatous Polyp of Colon
- Trial name
- NCT04017845
- Testing
- FIT, Precolonoscopy cleansing regimen, Conventional Colonoscopy
- Where
- Iraq
- Volunteers
- 537 people, healthy volunteers welcome
- Sponsor
- Lewai Sharki Abdulaziz, MSc PhD
Colorectal Carcinoma
A Multilevel Approach for Improvement in Screening of Colorectal Cancer in Rural Communities, The Screen to Save Trial
This clinical trial determines the feasibility of a multilevel approach to improve colorectal cancer screening within two rural regions of the Fred Hutchinson Cancer Research Center/University of Washington Consortium catchment…
- Trial name
- NCT05291988
- Testing
- Educational Intervention, Fecal Immunochemical Test, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Colorectal Cancer, Inflammatory Bowel Diseases
The Deep South Surgical Equity Research Network: Addressing Socioecological Determinants of Health
Rationale: Older African Americans undergoing surgery are a vulnerable and growing population at high risk for poor surgical outcomes and disparities.
- Conditions
- Colorectal Cancer, Inflammatory Bowel Diseases, Diverticular Diseases, Social Behavior
- Trial name
- NCT05345054
- Testing
- no intervention
- Where
- 3 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Colonoscopy, Colorectal Cancer
Feasibility Trial of Magnetic-assisted Colonoscope Platform
Colorectal cancer (CRC) screening program can reduce colon cancer-related mortality. Current CRC screening methods include stool occult blood and DNA testing, blood based tests and radiologic tests.
- Trial name
- NCT05213741
- Testing
- Autonomous navigation of a magnetic colonoscope
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Colon Cancer, Colorectal Cancer
Does Genetic Susceptibility for Bleeding Affect Quantitative Faecal Immunochemical Test (qFIT) Results?
Quantitative faecal immunochemical testing (qFIT) is used to test for blood within faeces that cannot always be visible. The presence of blood in the stool has been shown to be a finding where there may be a problem within the…
- Trial name
- NCT05329870
- Testing
- SNP array
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Edinburgh
Colorectal Cancer, Liver Metastasis
Surgical Recovery After Left Lateral Hepatic Sectionectomy: Laparoscopic Versus Open Surgery.
The ORANGE II trial is a double blinded randomised controlled trial that will provide evidence on the merits of laparoscopic surgery in patients undergoing a left lateral hepatic sectionectomy in terms of time to functional…
- Conditions
- Colorectal Cancer, Liver Metastasis, Liver Disease
- Trial name
- ORANGE II (NCT00874224)
- Testing
- laparoscopic left lateral hepatic sectionectomy, open left lateral hepatic sectionectomy
- Where
- Netherlands
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Ulcerative Colitis, Colon Cancer
Study of Effects of L-Arginine in Colitis and Colon Cancer
The purpose of this study is to look at the importance of L-Arginine in the digestive tract. L-Arginine is an amino acid and is important in making proteins within the cell.
- Trial name
- NCT01091558
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Colorectal Neoplasm, Colonic Polyps
Clinical Study of Real Time Colorectal Polyp Diagnosis During Colonoscopy - the VALID Colonoscopy Study
The investigators hypothesize that high definition colonoscopy with close focus narrow band imaging features has a high diagnostic accuracy for colorectal polyp histology, and can replace formal pathologic assessment in cases of…
- Trial name
- VALID (NCT01288833)
- Testing
- Close focus HD NBI Colonoscopy System
- Where
- 2 sites in United States
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Colo-rectal Cancer
New Genes in the Carcinogenesis of Colorectal Cancer
Colo rectal cancer is one of the greatest ,mutual malignancies worldwide ,accounting for an estimated 1.3 million new cases and >500,000 mortality ⁄ year .
- Trial name
- NCT03261752
- Testing
- blood sample
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Assiut University
Colonoscopy, Colonic Polyps
Implementation of Optical Diagnosis for Diminutive Polyps Amongst Endoscopists: Training and Long-term Quality Assurance
In this study, Dutch gastroenterologists who are certified for performing colonoscopies on FIT-positive patients in the Dutch population screening program are trained in optical diagnosis with validated methods.
- Trial name
- DISCOUNT2 (NCT02407925)
- Testing
- Feedback
- Where
- 13 sites in Netherlands
- Volunteers
- 3,144 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)