Clinical trials: Cancer-Associated Pain
Cancer, Pain
Cancer Pain Single Nucleotide Polymorphisms (SNPs)
Cancer pain is common in advanced cancer patients. Opioids are the mainstay of treatment in cancer pain. Responsiveness to and tolerability of opioids is, amongst others, determined by small variations in human DNA.
- Trial name
- NCT00956878
- Where
- Netherlands
- Volunteers
- 243 people
- Sponsor
- Erasmus Medical Center
Advanced Lung Cancer
A Clinical Study of Pain and Discomfort Associated With Advanced Lung Cancer
In this research, the patients with advanced lung cancer accompanied by pain and discomfort were treated by injecting freshly manufactured tissue permeable hyaluronan fragment HA35 into the tissue under abdominal adipose.
- Trial name
- NCT05852002
- Testing
- 35 kDa hyaluronan fragment
- Where
- Mongolia
- Volunteers
- 10 people
- Sponsor
- Nakhia Impex LLC
Pancreatic Cancer, Biliary Tract Cancer
Effect of Early Management on PAin and DEpression in Patients With PancreatoBiliary Cancer, EPADE-PB
Effect of Early management on PAin and DEpression in patients with PancreatoBiliary Cancer, EPADE-PB Purpose To determine whether early palliative care integrated with usual oncologic care with automated symptom monitoring can…
- Conditions
- Pancreatic Cancer, Biliary Tract Cancer, Cancer Pain, Depression
- Trial name
- EPADE-PB (NCT01589328)
- Testing
- Early Palliative care integrated with usual oncologic care
- Where
- South Korea
- Volunteers
- 288 people
- Sponsor
- National Cancer Center, Korea
Pancreas Cancer, Biliary Tract Cancer
Surgery Plus Celiac Nerve Block for Long-term Pancreatic Cancer Pain Control
This is a randomized study of surgery plus chemical nerve block versus surgery plus placebo for pain control in subjects with pancreatic cancer.
- Trial name
- NCT02002806
- Testing
- Alcohol Injection
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Indiana University
Chemotherapy Induced Neuropathic Pain, Chemotherapy Induced Pain Neuropathy
Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain
A randomized study to determine safety and efficacy of a series of subcutaneous (SC) injections of HAL in patients with CINP, compared to matching placebo injections.
- Conditions
- Chemotherapy Induced Neuropathic Pain, Chemotherapy Induced Pain Neuropathy, Chemotherapy Induced Pain
- Trial name
- NCT06848348
- Testing
- Halneuron, Halneuron (Open Label Extension)
- Where
- 25 sites in United States
- Volunteers
- 240 people
- Sponsor
- Dogwood Therapeutics Inc.
Cancer Pain
A Study to Compare Safety and Efficacy of Osmotic Release Oral Syytem (OROS) Hydromorphone Hydrochloride (HCl) With Morphine Sustain Release (SR) in Participants With Cancer Pain
The purpose of this study is to evaluate the effectiveness and safety of Osmotic Release Oral System (OROS) hydromorohone Hydrochloride (HCl) compared with morphine sustain release (SR) in participants with chronic (lasting a…
- Trial name
- NCT00803283
- Testing
- Hydromprphone Hydrochloride (HCl) OROS, Morphine Sustain Release (SR)
- Volunteers
- 2 people
- Sponsor
- Johnson & Johnson Taiwan Ltd
Cancer Pain, Non Small Cell Lung Cancer
TEAS for the Treatment of Pain in Bone Metastases of Lung Cancer
This multicenter, prospective, randomized controlled research study aims to objectively evaluate the role of transcutaneous electrical acupoint stimulation (TEAS), which combines the theory of acupuncture with transcutaneous…
- Conditions
- Cancer Pain, Non Small Cell Lung Cancer, Bone Metastases, Acupuncture
- Trial name
- NCT05730972
- Testing
- Transcutaneous electrical acupoint stimulation, Routine palliative treatment
- Volunteers
- 188 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Cancer Pain
An Efficacy and Safety Study of Hydromorphone Oral Osmotic System (OROS) in Korean Participants With Cancer Pain
The purpose of this is study to evaluate improvement of sleep disorder caused by cancer pain after the administration of Hydromorphone Oral Osmotic System (OROS) in Korean participants with cancer.
- Trial name
- NCT00766831
- Testing
- Hydromorphone
- Volunteers
- 190 people
- Sponsor
- Janssen Korea, Ltd., Korea
Cancer
E-MOSAIC Electronic Tool to Monitor Symptoms
RATIONALE: A hand held electronic tool used to monitor symptoms and assess quality of life may improve communication between patients and their doctors and improve the ability to plan treatment for patients with advanced cancer…
- Trial name
- NCT00477919
- Where
- 7 sites in Switzerland
- Volunteers
- 264 people
- Sponsor
- Swiss Cancer Institute
Cancer
Radiofrequency Splanchnic Denervation ,Neurolytic Retrocrural Celiac Plexus Block Chronic Upper Abdominal Cancer Pain
To compare between the efficacy of radiofrequency splanchnic denervation and neurolytic retrocrural celiac plexus block in chronic upper abdominal cancer pain
- Trial name
- NCT06678061
- Testing
- radiofrequency
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Dexmedetomidine
Dexmedetomidine in Splanchnic Nerve Neurolysis
Malignancy related abdominal and pelvic pain can be debilitating and affects survival as well as quality of life. Pain from cancer and its treatments can result in anxiety, depression, fear, anger, helplessness, and hopelessness…
- Trial name
- NCT05291364
- Testing
- Group 1, Group 2
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Pain, Analgesics, Opioid
A Repeated Dose Study of the Metabolism and Action Evaluation of OROS Hydromorphone HCI (Slow Release) Tablets in Patients With Chronic Pain
The purpose of this study was to characterize the steady-state pharmacokinetic (metabolism and action) profile of OROS hydromorphone HCI (slow release) in patients who required opioid therapy on a daily basis for chronic pain…
- Trial name
- NCT00410878
- Testing
- OROS Hydromorphone HCI (slow release)
- Volunteers
- 22 people
- Sponsor
- Alza Corporation, DE, USA
Cancer Pain
An Observation Study to Assess the Efficacy and Safety of Proportional Doses of Painkyl® in Patients With Breakthrough Cancer Pain
An open-label, single arm, observation study, to assess the efficacy and safety of proportional doses of Painkyl® in patients with breakthrough cancer pain.
- Trial name
- NCT05209906
- Testing
- Fentanyl Buccal Soluble Film
- Where
- Taiwan
- Volunteers
- 37 people
- Sponsor
- Mackay Memorial Hospital
Cancer, Cancer Pain
Effects of Su Jok Seed Therapy Application on Pain, Anxiety and Psychological Resilience in Patients Hospitalized in the Oncology Ward
The aim of this clinical trial is to determine the effects of su jok seed therapy on pain, anxiety and psychological resilience in patients hospitalized in the oncology ward.
- Trial name
- NCT06532175
- Testing
- Su-Jok
- Volunteers
- 80 people
- Sponsor
- Muş Alparslan University
Breast Cancer, Menopausal Symptoms
Acupuncture or Medication in Reducing Pain in Postmenopausal Women With Breast Cancer and Joint Pain
RATIONALE: Acupuncture may reduce joint pain in postmenopausal women with breast cancer. It is not yet known whether acupuncture is more effective than standard therapy analgesics in decreasing joint pain caused by aromatase…
- Conditions
- Breast Cancer, Menopausal Symptoms, Pain
- Trial name
- NCT00892268
- Testing
- acupuncture therapy, pain therapy
- Volunteers
- 68 people
- Sponsor
- University of Arizona
Osseous Spine Metastases
Evaluation of Vertebroplasty Associated With Radiotherapy for Spine Metastases (EVAR)
A randomized phase III study of palliative external beam radiotherapy (RTOG 97-14) has shown that 8 Gy in a single fraction is very effective in providing pain relief, with complete or partial improvement in pain seen in 66% of…
- Trial name
- NCT00267033
- Testing
- injection of orthopaedic cement into vertebral bodies
- Where
- France
- Volunteers
- 186 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Cancer
Study to Assess Effect of 8 Wks of Duloxetine Therapy on Breast Cancer Patients With Aromatase-Inhibitor Associated Pain
Many women with breast cancer who are treated with aromatase inhibitor medications develop aches and pains during treatment, and some develop numbness and tingling in their hands and feet.
- Trial name
- NCT01028352
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Michigan Rogel Cancer Center
Cancer, Pain
Computerized PAINRelieveIt Protocol for Cancer Pain Control in Hospice
The study purpose is to compare usual hospice care and PAINRelieveIt groups for effects on: (1) patient outcomes (analgesic adherence; worst pain intensity, satisfaction, and misconceptions) and lay caregiver outcome (pain…
- Trial name
- NCT02026115
- Testing
- PAINReportIt, PAINConsultN, PAINUCope
- Volunteers
- 262 people
- Sponsor
- University of Illinois Chicago
Pain, Cancer
An Efficacy and Safety Study of Fentanyl (JNS020QD) in Participants With Cancer Pain
The purpose of this study is to evaluate the safety and efficacy of fentanyl one-day transdermal patch (patch containing a drug that is put on the skin so the drug will enter the body through the skin) in participants switched…
- Trial name
- NCT00641667
- Testing
- Fentanyl
- Where
- Japan
- Volunteers
- 66 people
- Sponsor
- Janssen Pharmaceutical K.K.
Pain, Cancer Pain
PENS or TENS for Pain in Pancreatic Cancer
This study evaluates the effect of percutaneous electrical nerve stimulation (PENS) and transcutaneous nerve stimulation (TENS) for pain relieving in patients with pancreatic cancer.
- Conditions
- Pain, Cancer Pain, Pancreatic Cancer
- Trial name
- NCT03331055
- Testing
- PENS, TENS
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Fuda Cancer Hospital, Guangzhou