Clinical trials: Cancer-Associated Pain
Pulsed Radiofrequency, Super Voltage Pulsed Radiofrequency
Standard Pulsed Radiofrequency Versus Supervoltage Pulsed Radiofrequency Glossopharyngeal Nerve in Oropharyngeal Cancer Pain
The aim of this study is to evaluate the safety and efficacy of supervoltage pulsed radiofrequency glossopharyngeal nerve therapy versus standard pulsed radiofrequency in reduction of oropharyngeal cancer pain, through Visual…
- Conditions
- Pulsed Radiofrequency, Super Voltage Pulsed Radiofrequency, Glossopharyngeal Nerve, Oropharyngeal Cancer
- Trial name
- NCT06121102
- Testing
- Supervoltage pulsed radiofrequency glossopharyngeal nerve block, Standard voltage pulsed radiofrequency glossopharyngeal nerve block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute, Egypt
Chronic Pain, Cancer Pain
Clinical Classification of Pain in Breast Cancer Survivors
Breast cancer is the most common malignancy in women worldwide according to International Agency for Research on Cancer. Unfortunately, cancer survivors often face long-term symptoms that occur or persist after completion of…
- Conditions
- Chronic Pain, Cancer Pain, Breast Cancer
- Trial name
- NCT04219072
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Kutahya Health Sciences University
Breakthrough Pain, Palliative Medicine
Paediatric Breakthrough Pain Assessment
Many children and young people with life-limiting and life-threatening illnesses get sudden bursts of pain called breakthrough pain. At the moment, there aren't any good ways to measure this pain in children and young people.
- Conditions
- Breakthrough Pain, Palliative Medicine, Oncology Pain, Pediatric ALL
- Trial name
- BEACON (NCT06790719)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Cancer Pain, Refractory Pain
Transcranial Direct-current Stimulation (tDCS) Efficacy in Refractory Cancer Pain.
Pain is a common symptom in palliative care cancer patients and is often insufficiently relieved. The 2010 INCA report showed that France is not an exception to this worldwide observation (synopsis of the 2010 national survey).
- Trial name
- STIMPAL (NCT04683172)
- Testing
- Active Transcranial Direct Current Stimulation
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- Elsan
Cancer Pain
Unique Treatment of Oncology Pain in Advanced Cancer
This will be a proof-of-concept, single arm study with a maximum of 20 patients to evaluate preliminary analgesic efficacy and safety of Trichomylin® in patients with advanced cancer (male and female) who suffer from moderate to…
- Trial name
- UTOPIA-1 (NCT06533657)
- Testing
- Trichomylin® capsule (5 mg delta-9-tetrahydrocannabinol: 5 mg cannabidiol: 5 mg cannabichromene)
- Where
- 3 sites in Canada
- Volunteers
- 11 people
- Sponsor
- ZYUS Life Sciences Inc.
Pain Syndrome
Prevention of Taxane-associated Acute Pain Syndrome With Etoricoxib
A phase II randomized clinical trial was conducted to determine whether etoricoxib could prevent or ameliorate the incidence and/or severity of docetaxel-induced acute pain syndrome.
- Trial name
- NCT04565600
- Testing
- Etoricoxib
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Guangdong Provincial People's Hospital
Pain
The Effectiveness of a Patient Self-reported Pain Scoring Tool and a Satisfaction Survey on Cancer Pain Management
The purpose of this survey is to investigate the usefulness of a patient self-reported scoring tool on patient satisfaction improvement.
- Trial name
- NCT01829828
- Testing
- No intervention
- Volunteers
- 587 people
- Sponsor
- Janssen Korea, Ltd., Korea
Pain
Clinical Usefulness and Quality of Life of OROS Hydromorphone in Patients Who Have Not Been Treated With a Strong Opioid
The primary purpose of this study is to evaluate the usefulness of hydromorphone to treat cancer pain in patients who have not been treated with a strong opioid.
- Trial name
- NCT01532895
- Testing
- Hydromorphone HCI OROS
- Where
- 11 sites in South Korea
- Volunteers
- 400 people
- Sponsor
- Janssen Korea, Ltd., Korea
Chronic Pain, Cancer Pain
UDOPAL Study: Home-Based Interventional Approach to Pain Management in Home-Hospitalized Patients
The UDOPAL Study proposes an innovative home-based care approach for the management of pain in patients admitted to the Home Hospitalization Unit (UHD).
- Conditions
- Chronic Pain, Cancer Pain, Neuropathic Pain, Palliative Care
- Trial name
- UDOPAL (NCT07265492)
- Testing
- UDOPAL model
- Volunteers
- 100 people
- Sponsor
- Hospital de Manises
TO STUDY EMERGENCY CANCER PAIN PATTERNS AND TREATMENT ADEQUACY.
A Observational Study of Assessment and Treatment Adequacy of Emergency Cancer Pain in Tertiary Cancer Hospital
EMERGENCY CANCER PAIN MANAGEMENT HAS BEEN INCONSISTENT AND INADEQUATE ACROSS THE GLOBE. THIS STUDY AIMS TO KNOW EMERGENCY ROOM CANCER PAIN PATTERNS AND TREATMENT ADEQUACY IN TERTIARY CARE CANCER HOSPITALS.
- Trial name
- NCT01635478
- Volunteers
- 100 people
- Sponsor
- Tata Memorial Hospital
Cancer
Pain Management in Cancer Patients Using a Mobile Application
The investigators have developed a mobile application (for use on smart phones) to help cancer patients better manage cancer pain.
- Trial name
- ePAL (NCT02069743)
- Testing
- ePAL Mobile Application
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- Massachusetts General Hospital
Breakthrough Cancer Pain
Effectiveness and Tolerance of Inhaled Fentanyl Aerosol (25µg/Dose) in Chinese Patients With Breakthrough Cancer Pain
Breakthrough cancer pain (BTcP) is a common problem in patients with cancer. This is a phase I/IIa, pharmacokinetic, dose-response and safety study of inhaled fentanyl aerosol (25µg/dose) in Chinese patients with breakthrough…
- Trial name
- NCT04713189
- Testing
- Inhaled fentanyl aerosol
- Volunteers
- 96 people
- Sponsor
- Lee's Pharmaceutical Limited
Bone Metastases
ExAblate Conformal Bone System Treatment of Metastatic Bone Tumors for the Palliation of Pain
A study to evaluate the safety and initial effectiveness of the ExAblate 2100 Conformal Bone System in the treatment of pain resulting from metastatic bone tumors.
- Trial name
- NCT00981578
- Testing
- ExAblate 2100
- Where
- 5 sites in United States
- Volunteers
- 37 people
- Sponsor
- InSightec
Cancer Pain, Analgesic Drugs
Adequacy of Pain Treatment in Radiotherapy
Aim of the study is to evaluate adequacy of pain treatment in oncologic patients, accessing to Radiotherapy Unit
- Trial name
- NCT03550599
- Testing
- Patients accessing to Radiotherapy Unit
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Cancer
Methadone Associated With Morphine for Cancer Pain
The study was prospective, randomized. Patients with cancer pain were evaluated, one group receiving methadone with morphine and another group receiving morphine as the only opioid.
- Trial name
- NCT03324815
- Testing
- Morphine, Methadone
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Cancer Pains
Change the Dose Frequency of Controlled-Release Oxycodone to Refractory Pain
Many patients with cancer experience moderate to severe pain that requires treatment with strong opioids, of which oxycodone and morphine are examples, they are widely applied in clinical treatment because of sustained-released…
- Trial name
- NCT03639415
- Testing
- Increasing the Controlled-Release Oxycodone dose frequency
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fujian Cancer Hospital
Pain, Neoplasms
CORAL - Cebranopadol Versus Morphine Prolonged-release in Patients With Chronic Moderate to Severe Pain Related to Cancer
Pain is one of the most common symptoms associated with malignant tumor. The purpose of this trial is to determine whether cebranopadol is as effective in patients with cancer related pain as morphine sulfate prolonged release…
- Conditions
- Pain, Neoplasms, Chronic Pain
- Trial name
- CORAL (NCT01964378)
- Testing
- Cebranopadol, Morphine Prolonged Release
- Where
- 42 sites in Austria, Belgium and 12 more
- Volunteers
- 200 people
- Sponsor
- Tris Pharma, Inc.
Osteoarthritis, Rheumatoid Arthritis
Efficacy and Safety of Buprenorphine Transdermal Patch in Non-cancer Pain of Moderate Intensity
This is a phase IV, open-label and single-arm study of patients with non-malignant pain due to osteoarthritis, rheumatoid arthritis, low back pain and joint/muscle pain, who were not responding to non-opioid analgesics.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Lower Back Pain, Joint Pain
- Trial name
- NCT02519387
- Testing
- Buprenorphine Transdermal Patch
- Where
- 3 sites in Malaysia
- Volunteers
- 78 people
- Sponsor
- Mundipharma Pharmaceuticals Sdn. Bhd.
Pain Cancer
Subcutaneous Versus Intravenous Morphine When Switching From Oral to Parenteral Route in Palliative Cancer Patients
The investigators aim to establish whether the intravenous or the subcutaneous route of administration has clinically significant advantages when parenteral administration of morphine is started with a combination of continuous…
- Trial name
- SIM (NCT05236647)
- Testing
- Morphine
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University Hospital, Akershus
Limbs Arthrosis, Non Arthrosic Limbs Arthralgia
Association of Transcutaneous Electrical Nerve Stimulation and Hypnosis
At Saint-Antoine's hospital, in CETD a multidisciplinary team takes care of patients with chronic pain. Free-drug techniques are available to reduce their consumption of analgesics.
- Conditions
- Limbs Arthrosis, Non Arthrosic Limbs Arthralgia, Chronic Lomboradiculalgia, Chronic Back Pain
- Trial name
- HYPTENS (NCT01944150)
- Testing
- Transcutaneous electrical nerve stimulation, Transcutaneous electrical nerve stimulation and hypnosis
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris