Clinical trials: Cancer-Associated Pain
Chronic Pelvic Cancer Pain
Superior Hypogastric Plexus Block Versus Pulsed Radiofrequency for Chronic Pelvic Cancer Pain
Cancer-related pain represents a major challenge for both clinicians and patients. This pain can be associated directly with the cancer or with certain treatments administered to the patient.
- Trial name
- NCT03228316
- Testing
- superior hypogastric plexus block, pulsed radiofrequency
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Carpal Tunnel Syndrome
Safety and Efficacy of Lidoderm (Lidocaine Patch 5%) in Treating Moderate to Severe Pain Associated With Carpal Tunnel Syndrome
The purpose of this study is to evaluate the analgesic efficacy and safety of the lidocaine patch 5% compared to placebo in patients with moderate to severe pain associated with carpal tunnel syndrome.
- Trial name
- NCT00266214
- Testing
- lidocaine patch 5%
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Severe Caner Pain
A Study to Assess the Safety and Tolerability of Oxycodone Hydrochloride 50mg/mL Administered as an Infusion
Assessing the safety and tolerability of Oxycodone Hydrochloride 50mg/mL in subjects with severe cancer pain.
- Trial name
- NCT00626600
- Testing
- Oxycodone Hydrochloride
- Where
- United Kingdom
- Volunteers
- 33 people
- Sponsor
- Mundipharma Research Limited
Sacral Tarlov Cysts, Symptomatic Sacral Cysts
Long-Term Outcomes of Different Surgical Techniques for Sacral Tarlov Cysts: A Prospective Cohort Study
Brief Summary The goal of this observational study is to evaluate the long-term outcomes of different surgical techniques for sacral Tarlov cysts in adult patients aged 18-75 years diagnosed with symptomatic sacral Tarlov cysts.
- Conditions
- Sacral Tarlov Cysts, Symptomatic Sacral Cysts, Chronic Pain Related to Sacral Cysts, Neurological Dysfunction Associated With Tarlov Cysts
- Trial name
- NCT06756984
- Testing
- Partial Cyst Wall Resection with Nerve Root Sleeve Plasty, Partial Cyst Wall Resection with Nerve Root Sleeve Reinforcement and Reconstruction:, Autologous Fat/Muscle with Fibrin Glue Microscopic Cyst Filling
- Volunteers
- 150 people
- Sponsor
- Beijing Jishuitan Hospital
Sarcoma, Childhood Sarcoma of Soft Tissue
Brief Title Mechanisms of Cancer-Related Pain and Opioid Use Among Adolescents and Young Adult Sarcoma Survivors: Pilot Feasibility Study
This study generates information on the feasibility and acceptability of a 3-month ecological momentary assessment (EMA) protocol to assess chronic pain and opioid use in adolescent and young adult (AYA) sarcoma survivors.
- Trial name
- NCT07402577
- Testing
- Non Intervention Study
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Roswell Park Cancer Institute
Cancer
Immediate-Release Oxycodone Capsules Study in Cancer Pain
The efficacy of dose titration of OxyNorm™(Oxycodone) immediate-release capsules versus morphine immediate-release tablets in the treatment of cancer pain.
- Trial name
- NCT01675622
- Testing
- Oxycodone, Morphine
- Volunteers
- 242 people
- Sponsor
- Mundipharma (China) Pharmaceutical Co. Ltd
Cancer-Related Pain
The Effectiveness of Progressive Muscle Relaxation Technique in Reducing Cancer-related Pain
This randomized controlled trial was designed to evaluate the effectiveness of the Progressive Muscle Relaxation (PMR) technique in reducing Cancer-related Pain (CRP) in patients receiving palliative care in Jordan.
- Trial name
- NCT04436705
- Testing
- Progressive Muscle Relaxation (PMR) technique
- Volunteers
- 148 people
- Sponsor
- University of Jordan
Oncology, Pain, Acute
Utility of an APP for the Monitoring of Irruptive Oncological Pain
The present investigation aims at exploring the effect of including a pain app called Pain Monitor irruptive oncological pain for chronic pain patients' daily monitoring. Two conditions will be set: 1.
- Conditions
- Oncology, Pain, Acute, Pain, Chronic
- Trial name
- NCT03597737
- Testing
- Pain APP
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- Universitat Jaume I
Cancer Pain, Nutrition Disorders
Correlation Between the Analgesic Effect of Fentanyl Transdermal Patches and Nutritional Status in Cancer Pain Patients
The goal of this observational study is to investigate the correlation and quantitative relationship between the analgesic effect of fentanyl transdermal patches in cancer pain patients and their nutritional status.
- Trial name
- NCT06369961
- Testing
- transdermal fentanyl
- Where
- China
- Volunteers
- 151 people
- Sponsor
- Chongqing University Cancer Hospital
Cancer Pain, Nursing Students
Evaluation of the Effects of Traditional and E-Learning Methods in Cancer Pain Care Education on Learning Outcomes and Institutional Costs
Cancer pain is a significant clinical problem that directly affects patients' quality of life and requires nurses to be equipped with adequate knowledge and skills to provide effective care.
- Conditions
- Cancer Pain, Nursing Students, Nursing Education
- Trial name
- NCT07461974
- Testing
- e-learning, traditional group
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi
Disease (or Disorder); Intervertebral Disc, With Myelopathy (Manifestation)
NORSPAN Transdermal Patches Phase III Study In Non-Cancer Pain
This is a multiple-dose, double-blind, double-dummy, active-control, parallel-group, multi-center, safety and efficacy study.
- Trial name
- NCT01476774
- Testing
- Buprenorphine Transdermal System
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Mundipharma (China) Pharmaceutical Co. Ltd
Cognitive Dysfunction
Cognitive Dysfunction in Patients With Cancer Pain
To investigate the occurrence of cognitive dysfunction in cancer patients with pain in China.Analysis of patients with different cancer pain, different analgesic drugs and different treatments are associated with the severity of…
- Trial name
- NCT03641820
- Where
- China
- Volunteers
- 928 people
- Sponsor
- Fujian Cancer Hospital
Chronic Non-cancer Pain, Patient Education as Topic
Scool of Pain (SchooP): A Way to Create Value in Healthcare?
BACKGROUND: Chronic non-cancer pain (CNCP) is a disabling condition with radical consequences. Magic fix-it solutions do not exist. CNCP is a condition for life, calling for healthcare services supporting its management.
- Trial name
- SchooP (NCT07363746)
- Testing
- Pain school intervention
- Where
- Denmark
- Volunteers
- 82 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cancer Pain
Human Physiology and Self-Reported Pain Score
To assess whether the patient's self-reported pain level is associated with a multivariate physiological biomarker bias achieved in the actual clinical setting.
- Trial name
- NCT04053608
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Taichung Veterans General Hospital
Chemotherapy Induced Neuropathic Pain, Chemotherapy Induced Pain Neuropathy
Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain
A randomized study to determine safety and efficacy of a series of subcutaneous (SC) injections of HAL in patients with CINP, compared to matching placebo injections.
- Conditions
- Chemotherapy Induced Neuropathic Pain, Chemotherapy Induced Pain Neuropathy, Chemotherapy Induced Pain
- Trial name
- NCT06848348
- Testing
- Halneuron, Halneuron (Open Label Extension)
- Where
- 25 sites in United States
- Volunteers
- 240 people
- Sponsor
- Dogwood Therapeutics Inc.
Cancer, Pain
Cancer Pain Single Nucleotide Polymorphisms (SNPs)
Cancer pain is common in advanced cancer patients. Opioids are the mainstay of treatment in cancer pain. Responsiveness to and tolerability of opioids is, amongst others, determined by small variations in human DNA.
- Trial name
- NCT00956878
- Where
- Netherlands
- Volunteers
- 243 people
- Sponsor
- Erasmus Medical Center
Advanced Lung Cancer
A Clinical Study of Pain and Discomfort Associated With Advanced Lung Cancer
In this research, the patients with advanced lung cancer accompanied by pain and discomfort were treated by injecting freshly manufactured tissue permeable hyaluronan fragment HA35 into the tissue under abdominal adipose.
- Trial name
- NCT05852002
- Testing
- 35 kDa hyaluronan fragment
- Where
- Mongolia
- Volunteers
- 10 people
- Sponsor
- Nakhia Impex LLC
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Effect of Opioid Infusion Rate on Abuse Liability Potential of Intravenous Hydromorphone for Cancer Pain
In cancer inpatient settings, intravenous (IV) opioids are frequently administered in a bolus fashion in order to obtain immediate pain relief.
- Trial name
- NCT04296305
- Testing
- Hydromorphone, Questionnaire Administration
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- M.D. Anderson Cancer Center
Non-cancer Pain, Opioid Induced Constipation
Prucalopride Effects on Subjects With Chronic Non-cancer Pain Suffering From Opioid Induced Constipation
The study will evaluate the efficacy, safety and tolerability of prucalopride over 12 weeks of treatment in subjects aged 18 years and older with chronic non-cancer pain, suffering from opioid induced constipation.
- Trial name
- OIC (NCT01117051)
- Testing
- prucalopride
- Where
- Belgium
- Volunteers
- 174 people
- Sponsor
- Shire
Lung Cancer, Pain
Fentanyl Matrix in Lung Cancer Pain
The purpose of this study is to evaluate the usefulness of fentanyl matrix by assessing patients' satisfaction when administrating fentanyl matrix, a background pain treatment, and a breakthrough pain treatment to lung cancer…
- Trial name
- NCT01060137
- Testing
- fentanyl matrix
- Volunteers
- 268 people
- Sponsor
- Janssen Korea, Ltd., Korea