Clinical trials: Cancer-Associated Pain
Pancreatic Cancer, Pain
Invasive Treatment of Pain Associated With Pancreatic Cancer on Different Levels of WHO Analgesic Ladder
Pancreatic cancer is a difficult to treat disease, mainly due to the fact that diagnosis is made usually in the late stage of this condition.
- Trial name
- NCT02424279
- Testing
- Splanchnicectomy
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Medical University of Gdansk
Cancer, Palliative Care, Patient Care
Dexmedetomidine for Refractory Pain in Palliative Cancer Patients
The goal of this study is to find out whether the medication dexmedetomidine can be a safe and effective additional treatment for cancer patients whose pain is not well controlled by standard pain medicines (such as opioids).
- Conditions
- Cancer, Palliative Care, Patient Care, Pain Management, Dexmedetomidine Analgesia
- Trial name
- DEX-PAL (NCT07885475)
- Where
- 4 sites in Norway
- Volunteers
- 30 people
- Sponsor
- St. Olavs Hospital
Cancer Pain
Coeliac Plexus Neurolysis Versus Splanchnic Nerve Neurolysis
Pain is prevalent among patients with gastrointestinal cancers. Standard procedures such as coeliac plexus neurolysis (CPN) is effective in reducing pain, opioid requirement and related side effects for pancreatic cancer cases.
- Trial name
- NCT05541211
- Testing
- Coeliac plexus neurolysis, Splanchnic nerve neurolysis
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Cancer Pain
Improving Cancer Pain Management Through Teach-Back Educational Approach for Patients and Primary Caregivers: A Pilot Study
This randomized prospective quantitative pilot study compared teach-back method to standardized educational method in patient and caregiver to improve cancer pain management
- Trial name
- NCT05856292
- Testing
- Teach Back
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Bone Cancer, Bone Metastases
Study Comparing the Safety and Effectiveness of Magnetic Resonance Guided Focused Ultrasound (MRgFUS) and External Beam Radiation (EBRT) for Treatment of Metastatic Bone Tumors and Multiple Myeloma
The goal of this study is to collect comparative data on safety and efficacy of MR Guided Focused Ultrasound and External Beam Radiation for treatment of metastatic bone tumors or multiple myeloma.
- Conditions
- Bone Cancer, Bone Metastases, Pain
- Trial name
- NCT01091883
- Testing
- Exablate treatment, Radiation
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- InSightec
Pain, Inpatient
Pain Education to Improve Cancer Pain Management Patients
Cancer pain is one of the problems of treating cancer pain. Although, there is a WHO analgesic ladder to improve this problem, it is still inadequate pain control.
- Conditions
- Pain, Inpatient, Cancer
- Trial name
- NCT03205579
- Testing
- Video group, conventional group
- Where
- 2 sites in Thailand
- Volunteers
- 48 people
- Sponsor
- Mahidol University
Cancer
PROspective Non-interventional Open laBEl Trial for TARGIN in Korean Patients With Cancer Pain
The aim of the study is to evaluate the efficacy of TARGIN administration as an analgesic to Korean patients treated with opioid analgesics for moderate-to-severe cancer pain under conditions of daily practice.
- Trial name
- PROBE (NCT01719757)
- Testing
- Oxycodone/Naloxone
- Where
- South Korea
- Volunteers
- 359 people
- Sponsor
- Mundipharma Korea Ltd
Postmenopausal, Breast Cancer
Acupressure for Aromatase Inhibitor-Associated Musculoskeletal Symptoms in Patients With Breast Cancer
This is a randomized, double-blinded trial of self-acupressure to examine the effect of treatment on aromatase inhibitor (AI)-associated musculoskeletal symptoms (AIMSS) in postmenopausal women with breast cancer.
- Trial name
- NCT06228768
- Testing
- Acupressure
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan Rogel Cancer Center
Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain
Determining the Prognostic Value of Continuous Intrathecal Infusion
The purpose of this study will be to determine the efficacy and the prognostic value of a continuous intrathecal prognostic infusion test in an in-hospital setting for selecting patients who would have better long term outcomes…
- Conditions
- Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain, Vertebral Compression Fracture, Failed Back Surgery Syndrome
- Trial name
- NCT03523000
- Testing
- Continuous intrathecal prognostic infusion test, Bupivacaine, Fentanyl
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University Hospitals Cleveland Medical Center
Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy (CIPN)
Efficacy of Spinal Cord Stimulation in Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a frequent and debilitating side effect of many cancer treatments. It affects 28 to 48% of patients receiving chemotherapy.
- Conditions
- Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy (CIPN), Cancer-related Pain
- Trial name
- CHEMOSTIM (NCT07579611)
- Testing
- Spinal cord stimulation (FAST mode)
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Tumor, Cancer
Oral Bicarbonate as Adjuvant for Pain Reduction in Patients With Tumor Related Pain
The purpose of this study is to: Determine how well people tolerate sodium bicarbonate taken by mouth in higher doses than those usually given for heartburn. Determine if sodium bicarbonate can reduce cancer-related pain.
- Conditions
- Tumor, Cancer, Pain, Malignant Solid Tumor
- Trial name
- NCT01846429
- Testing
- Sodium Bicarbonate
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Head and Neck Cancer, Oral Complications
Sargramostim in Decreasing Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer
RATIONALE: Sargramostim may lessen symptoms of mucositis in patients receiving radiation therapy for head and neck cancer. It is not yet known if sargramostim is more effective than no treatment in reducing mucositis caused by…
- Conditions
- Head and Neck Cancer, Oral Complications, Radiation Toxicity
- Trial name
- NCT00008398
- Testing
- sargramostim, quality-of-life assessment, radiation therapy
- Where
- 236 sites in United States, Canada
- Sponsor
- Radiation Therapy Oncology Group
Breast Cancer, Musculoskeletal Pain
TCM as an Adjuvant Treatment in Breast Cancer Patients
Chinese herbs can alleviates the side effects caused by conventional treatment in breast cancer patients and affects the syndrome element differentiation by altering the specific set of proteomes at specific time point of…
- Trial name
- NCT04843865
- Testing
- Chinese Herbs
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- Universiti Tunku Abdul Rahman
Cancer Related Pain
NanaBis™ an Oro-buccal Administered delta9-Tetrahydrocannabinol (d9-THC) & Cannabidiol (CBD) Medicine for the Management of Bone Pain From Metastatic Cancers
This is a multi-centre, long term, double blind, clinical protocol for NanaBis™ as a monotherapy treatment in participants 18-75 years of age with cancer related pain.
- Trial name
- NCT04808531
- Testing
- NanaBis™, Oxycodone CR, Oxycodone IR
- Volunteers
- 360 people
- Sponsor
- Medlab Clinical
Pain, Advanced Cancer
Sativex® for Relieving Persistent Pain in Participants With Advanced Cancer
This 9-week study aimed to determine the efficacy, safety and tolerability of nabiximols (Sativex®) as an adjunctive treatment, compared with placebo in relieving uncontrolled persistent chronic pain in participants with advanced…
- Trial name
- NCT01262651
- Testing
- Nabiximols
- Where
- 72 sites in United States, Belgium and 10 more
- Volunteers
- 397 people
- Sponsor
- GW Pharmaceuticals Ltd
Pain, Chronic
Development and Evaluation of a Methadone Protocol for Severe Chronic Pain Management
Methadone is a synthetic mu opioid agonist that has been proved as clinically effective in pain management. However, methadone usage for pain control in Thailand has been limited because physicians are not familiar with its…
- Trial name
- NCT02335398
- Testing
- Methadone
- Where
- Thailand
- Volunteers
- 34 people
- Sponsor
- Mahidol University
Standard Opioid Analgesic Treatment of Cancer-related Chronic Pain.
Efficacy and Safety of FITpatch Compared to Standard Opioid Treatment in Cancer Pain (FT-015-IN)
Primary objectives: To determine non-inferiority of FITpatch with regard to efficacy compared to standard opioid treatment To assess the safety of FITpatch compared to standard opioid treatment Secondary objectives: To assess the…
- Trial name
- NCT00279344
- Testing
- Fentanyl (Matrifen)
- Volunteers
- 220 people
- Sponsor
- Nycomed
Neoplasm Metastasis
Pilot Study to Test the Feasibility and the Efficacy of the German Language Adapted PRO-SELF© Plus Pain Control Program
The purpose of this pilot study is to refine and test an advanced and adapted German version of the PRO-SELF© Plus Pain Control Program (PCP), an educational intervention directed at cancer pain patients and their families to…
- Trial name
- PEINCA (NCT00920504)
- Testing
- German PRO-SELF(c) Plus Pain Control Program (PCP), Standard Care
- Where
- Germany
- Volunteers
- 39 people
- Sponsor
- University Hospital, Basel, Switzerland
Cancer Pain
IV PCA With or Without Continuous Dose vs Oral Opioid to Maintain Analgesia for Severe Cancer Pain After Successful Titration
Based on the previous HMORCT09-2, the results show that IV PCA for analgesia maintenance improvements control of severe cancer pain after successful titration.
- Trial name
- NCT04785768
- Testing
- Hydromorphone Hydrochloride Injection, Morphine Sulfate Sustained-release Tablets
- Where
- China
- Volunteers
- 1,372 people
- Sponsor
- Fujian Cancer Hospital
Mucositis, Pain
Acupuncture for Mucositis Pain in Cancer Care
This research is being done to see if acupuncture helps relieve mucositis pain in patients with leukemia who are undergoing chemotherapy.
- Conditions
- Mucositis, Pain, Leukemia
- Trial name
- NCT00549835
- Testing
- Real Acupuncture
- Where
- United States
- Sponsor
- Johns Hopkins University