Clinical trials: Cancer-Associated Pain
Refractory Cancer Pain, Cancer Pain
Hydromorphone With Electroacupuncture and Ear Acupoint Pressing for Refractory Cancer Pain
This trial aims to address refractory cancer pain (RCP). It will explore the synergistic efficacy and safety of hydromorphone hydrochloride sustained-release tablets (HHST) combined with electroacupuncture (EA) and ear acupoint…
- Trial name
- NCT07489625
- Testing
- Hydromorphone Hydrochloride Extended-Release Tablets, Electroacupuncture, Ear Acupoint Pressing Beans
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Qinghai Red Cross Hospital
Cancer Pain
Long-term Effects of Methadone for Cancer Pain
The methadone is an useful opioid for the cancer pain treatment, mostly used in second or last line during the opioid rotation. The Methadone had an anti-MNDA effect, and clinicians agree that the methadone could have an effect…
- Trial name
- NCT02856399
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Pain Cancer
Effectiveness of a Patient Therapeutic Education Program in Improving Pain Management
Pain is one of the most feared and burdensome symptoms experienced by cancer patients. Its prevalence has been estimated by INCa1 in 2012 at 48% in patients undergoing cancer treatment, and unrelieved pain is directly associated…
- Trial name
- EFFADOL-K (NCT03297723)
- Testing
- Therapeutic education Programm
- Where
- 16 sites in France
- Volunteers
- 167 people
- Sponsor
- Centre Francois Baclesse
Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS), Joint Pain
Pilot Study of Hydroxychloroquine for the Treatment of AIMSS
The purpose of this study is to evaluate the effectiveness of hydroxychloroquine sulfate (a type of drug commonly used to treat joint pain caused by inflammation, swelling) in reducing joint pain associated with Aromatase…
- Conditions
- Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS), Joint Pain, Breast Cancer
- Trial name
- AIMSS (NCT07825454)
- Testing
- Hydroxychloroquine Sulfate (HCQ)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Indiana University
Cancer Pain
Transdiscal vs Paravertebral Neurolytic Splanchnic Nerve Block for Upper Abdominal Cancer Pain
This study aims to compare the efficacy of fluoroscopy-guided paravertebral (PV) and transdiscal (TD) approaches for splanchnic nerve neurolysis in patients with upper abdominal cancer-related pain (e.g., gastric, pancreatic, and…
- Trial name
- NCT07445386
- Testing
- transdiscal splanchnic neurolysis, paravertebral splanchnic neurolysis
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ankara Etlik City Hospital
Cancer-Related Pain
Buprenorphine for Cancer Pain
This study will evaluate patients on both buprenorphine and full agonist opioids (FAO) to assess for withdrawal symptoms. Patients will be evaluated by clinicians and using validated tools to assess for pain and withdrawal.
- Trial name
- NCT05910190
- Testing
- Use of buprenorphine with FAO > 30 OME, CPM Rx application use
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Fox Chase Cancer Center
Chronic Pain
Prescription Opioid Misuse Assessment
Chronic pain is a worldwide health problem due to its high prevalence and its difficult management with a significant impact on quality of life. Pain and addiction co-occur frequently.
- Trial name
- POMA4 (NCT03195374)
- Testing
- Prescription Opioid Misus Index
- Where
- France
- Volunteers
- 951 people
- Sponsor
- University Hospital, Clermont-Ferrand
Constipation
Efficacy and Safety of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain
This study will evaluate the efficacy and safety of tegaserod in opioid-induced constipation in patients with non-cancer pain.
- Trial name
- NCT00365820
- Testing
- Tegaserod
- Where
- 59 sites in United States
- Volunteers
- 670 people
- Sponsor
- Novartis
Bone Metastases, Multiple Myeloma
ExAblate (MRgFUS) Treatment of Metastatic Bone Tumors for the Palliation of Pain
A Pivotal Study to Evaluate the Effectiveness and Safety of ExAblate Treatment of Metastatic Bone and Multiple Myeloma Tumors for the Palliation of Pain in Patients Who are not Candidates for Radiation Therapy
- Trial name
- NCT00656305
- Testing
- ExAblate MRfFUS
- Where
- 14 sites in United States, Canada and 3 more
- Volunteers
- 147 people
- Sponsor
- InSightec
Advanced Cancer, Pain
Lenalidomide (Revlimid) for the Treatment of Refractory Cancer Pain
The goal of this clinical research study is to learn if lenalidomide can help to treat uncontrolled pain caused by advanced cancer. Primary Objectives: 1.
- Trial name
- NCT00684242
- Testing
- Lenalidomide
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- M.D. Anderson Cancer Center
Non-Cancer Pain,Musculoskeletal Pain,Chronic Pain,Acute Pain
Real-World Study of Acupuncture for Pain Control
The goal of this observational study is to evaluate the real-world effectiveness of an acupuncture-first stepped care pathway for pain management in adults aged 18 years and older receiving routine outpatient clinical care for…
- Trial name
- NCT07454083
- Testing
- Acupuncture-First Stepped Care Pathway (Routine Clinical Care)
- Volunteers
- 300 people
- Sponsor
- Qi's Clinic
Cancer Pain, Pain
Evaluation of ESMO Guidelines Applicability and Adherence in Cancer Pain Management in the Palliative Care Setting
Palliative care (PC) is focused on improving the Quality of Life (QoL) of patients living with a life-threatening illness. Each year, an estimated 40 million people need PC management in the world.
- Conditions
- Cancer Pain, Pain, Cancer
- Trial name
- NCT04795739
- Where
- 8 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Antea Foundation
Non Cancer Pain
Targin for Non-cancer Pain
To determine the improvement in symptoms of constipation in subjects receiving treatment with oxycodone/naloxone prolonged release tablets (OXN) compared to oxycodone prolonged release tablets (OXY) based on the Bowel Function…
- Trial name
- NCT01918098
- Testing
- Oxycodone/naloxone prolonged release tablets
- Where
- 31 sites in China
- Volunteers
- 230 people
- Sponsor
- Mundipharma (China) Pharmaceutical Co. Ltd
Cancer Pain
Effectiveness of a Pain Neuroscience Education Program in Adults With Cancer Pain
IASP defines "pain" as "an unpleasant sensory and emotional experience associated with or resembling that associated with actual or potential tissue damage".
- Trial name
- NCT05581784
- Testing
- Pain neuroscience education, Conventional management or Usual care
- Where
- 4 sites in Chile, Colombia and 1 more
- Volunteers
- 80 people
- Sponsor
- Instituto Neurociencia Del Dolor
Quality of Life, Breakthrough Cancer Pain
Observational Registry Study of Quality of Life When Treating BTcP With Abstral
This Observational Registry study is designed to collect self-reported Transmucosal Immediate Release Fentanyl (TIRF) Risk Evaluation and Mitigation Strategy (REMS) Access program-enrolled patient experience with breakthrough…
- Trial name
- RELIEF (NCT01936636)
- Testing
- Fentanyl
- Where
- 36 sites in United States
- Volunteers
- 164 people
- Sponsor
- Galena Biopharma, Inc.
Cancer, Neuropathy
The Effect of Tennis Ball on Balance and Quality of Life in Cancer Patients With Neuropathy.
This research; It was aimed to evaluate the effect of myofascial release using a tennis ball on balance and quality of life in cancer patients who developed peripheral neuropathy.
- Conditions
- Cancer, Neuropathy, Therapy-Associated Cancer
- Trial name
- NCT06376344
- Testing
- myofascial release with tennis ball
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Selcuk University
Post-mastectomy Pain Syndrome, Chronic Post-surgical Pain
Perioperative Pregabalin and Lidocaine to Reduce Chronic Breast Cancer Pain
Breast tissue and the areas surrounding the breast contain many small to medium-sized nerves. During surgery on the breast, these nerves can be inadvertently cut or damaged.
- Trial name
- PLAN (NCT02240199)
- Testing
- Intraoperative Intravenous Lidocaine Infusion, Perioperative Pregabalin
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Breast Cancer
Short and Long Term Effects of a Physical Therapy Program After Breast Cancer Surgery
Objectives: To evaluate the pressure pain threshold, shoulder biomechanics, cardiorespiratory function and the quality of life associated with the short and long-term physical therapy rehabilitation following breast cancer…
- Trial name
- NCT04116281
- Testing
- Rehabilitation after breast cancer surgery
- Where
- Chile
- Volunteers
- 36 people
- Sponsor
- Universidade Federal de Sao Carlos
Chronic Pain
Safety Study to Assess Opiate Withdrawal Signs and Symptoms in Opioid Dependent Patients
This study will evaluate whether crushed EMBEDA capsules induce clinical opiate withdrawal signs and symptoms in opioid-dependent patients with chronic non-cancer pain who are stabilized on EMBEDA.
- Trial name
- NCT01100437
- Testing
- EMBEDA™ (morphine sulfate/naltrexone hydrochloride) crush, EMBEDA™ (morphine sulfate/naltrexone hydrochloride) whole
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Pfizer
Cancer Pain, Palliative Care
e-Natureza Blue Care: Nature-based Virtual Reality and Pain Perception
This randomized clinical trial aims to evaluate the effectiveness of immersive nature-based virtual reality in managing chronic pain among oncology patients.
- Trial name
- e-NatBlue (NCT07053228)
- Testing
- Nature-based virtual reality, Standard Pain Management
- Where
- Brazil
- Volunteers
- 130 people
- Sponsor
- Hospital Israelita Albert Einstein