Clinical trials: Cannabis User
Driving Under the Influence of Cannabis
Pilot-Study for the Comparison of Biomarkers Between Regular Cannabis Users and Non-Users
The relevance of driving under the influence of cannabis is becoming increasingly important in the context of legalization. However, the measurement of tetrahydrocannabinol (THC) blood concentration is an inadequate marker for…
- Trial name
- CANBiome (NCT06975020)
- Testing
- Participants will prepare their cannabis product ad libitum and inhale the prepared product as usual for a maximum of 15 minutes.
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Basel
Cannabis
A Study of Ingested Cannabidiol in Healthy Occasional Cannabis Users
The purposes of this study are 1) to determine if the administration of different low doses of oral CBD (20 mg, 50 mg, 100 mg and 200 mg) result in detectable subjective pleasant drug effect compared to placebo and 2) to…
- Trial name
- NCT05407285
- Testing
- Cannabis 20 mg,, Cannabis 50 mg, Cannabis 100 mg
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Cannabis User
Effect of Acute Exercise on Cognitive Functions and Blood Markers of Brain Plasticity in Regular Chronic Cannabis Users
The endocannabinoid system (ECS) is a complex endogenous signaling system made up of transmembrane cannabinoid receptors (CB1 and CB2 receptors), their endogenous lipid-derived ligands (the endocannabinoids - eCBs), and enzymes…
- Trial name
- CANNABEX (NCT06081218)
- Testing
- activity test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Cannabis User
Online Brief Advice Intervention for Heavy Cannabis Users
This project will evaluate whether a brief online intervention focused on cannabis withdrawal can increase awareness and insight about cannabis use disorder among daily cannabis users.
- Trial name
- Recalibrate (NCT07379736)
- Testing
- Educational video, Relaxation video
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King's College London
Cannabis Use
Using Implementation Intentions to Reduce Cannabis Use
The study will recruit frequent users of cannabis (defined at least fortnightly use) and randomize them either to: (1) form implementation intentions by linking situations in which they are tempted to use cannabis with strategies…
- Trial name
- NCT03845842
- Testing
- Volitional help sheet
- Where
- United Kingdom
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Cannabis, THC
Modulation of THC Effects by CBD: a Dose-ranging Study
The purposes of this study are 1) to determine if CBD modulates THC-induced acute psychoactive effects at different CBD:THC ratios, compared with the control product (0:20, 20:20, 40:20, 80:20, 120:20) and 2) to determine if…
- Trial name
- SPECTRE (NCT06099379)
- Testing
- ∆9-tetrahydrocannabinol
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Recreational Cannabis Use
Emotional Brain Processes in Recreational Cannabis Users
This fMRI study investigates neural correlates of emotion regulation, emotion processing and craving in recreational cannabis users.
- Trial name
- NCT02801214
- Testing
- fMRI
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Cannabis Intoxication
Cannabis Impairment Detection Device Study
The goal of this study is to develop a cannabis impairment detection device in adult cannabis users. The main question[s] it aims to answer are: Is the investigational device accurate and reliable at detecting cannabis…
- Trial name
- NCT07122349
- Testing
- Cannabis Impairment Test
- Where
- Canada
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Gaize
COPD, Insomnia
Colorado Marijuana Users Health Cohort
In Colorado, marijuana is currently used for both recreational and medicinal purposes.To learn more about the positive and negative long term medical effects of marijuana use.
- Conditions
- COPD, Insomnia, Cannabis
- Trial name
- NCT02735954
- Testing
- Marijuana
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
Cannabis Use, Cannabis
Investigating Real-world Stress-related Mechanisms in Heavy Cannabis Users
This research project proposes a novel approach to elucidate the biological adaptations associated with heavy cannabis use and to assess whether such adaptations are predictive of higher cannabis craving in response to both…
- Conditions
- Cannabis Use, Cannabis, Cannabis Abuse
- Trial name
- CLR2 (NCT05833230)
- Testing
- Intensive Day Monitoring
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Yale University
Cannabis
Transcranial Magnetic Brain Stimulation to Reduce Cannabis Use in Heavy Cannabis Users
The growing legalization of cannabis across the U.S. is associated with increases in cannabis use, and accordingly, an increase in the number of individuals with cannabis use problems, including cannabis use disorder (CUD).
- Trial name
- iCURE (NCT05401929)
- Testing
- iTBS
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Duke University
Marijuana Abuse, Marijuana Dependence
Attempts to Stop/Reduce Marijuana Among Dependent Users
The purpose of the study is to determine why and how marijuana users stop or reduce their marijuana use.
- Trial name
- NCT01039415
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Cannabis Dependence
Neural Indices Associated With Relapse in Cannabis Dependence
The aim of this fMRI study is to investigate neural indices of relapse in cannabis dependence. The development and maintenance of drug addictions have been associated with deficits in cognitive control, craving and impaired…
- Trial name
- NCT02801422
- Testing
- fMRI
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Cannabis Use
Electrophysiological Study of the Functioning of Magnocellular Visual Pathway in Regular Cannabis Users
This study will evaluate the impact of regular use of cannabis on the spatial sensitivity of magnocellular system (visual event-related potential, visual ERP).
- Trial name
- CAUSA MAP (NCT02864680)
- Testing
- Electroretinography, Contrast sensitivity test during Electroencephalography, Visual simultaneity test during Electroencephalography
- Where
- France
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Memory
Galantamine Effects on Cognitive Function in Marijuana Users
To evaluate galantamine's effects on cognitive performance in marijuana users. Galantamine, an acetylcholine esterase inhibitor, is approved for treatment of Alzheimer's disease.
- Trial name
- NCT00969696
- Testing
- Galantamine
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yale University
Cannabis Dependence
Social and Emotional Brain Function in Cannabis Users
The aim of this functional magnetic resonance imaging (fMRI) study is to find out whether and how social and emotional brain function are altered in dependent cannabis users relative to healthy non-using control subjects after a…
- Trial name
- NCT02711371
- Testing
- fMRI
- Where
- Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Cannabis, Abuse Liability
Repeated CBD Administration and Cannabis Outcomes
This outpatient study examines how cannabidiol (CBD) affects the behavioral and pain-relieving effects of cannabis.
- Conditions
- Cannabis, Abuse Liability, Experimental Pain in Healthy Human Participants
- Trial name
- NCT07434895
- Testing
- Cannabidiol, Medium Dose, Cannabidiol, Higher Dose, Active Inhaled Cannabis
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Hannah Harris
Opioid Use Disorder
Evaluation of the Interactions of Cannabidiol (CBD) With Morphine
The purpose of this study is to analyze drug-drug interactions of CBD on co-administered Morphine as first step in understanding CBD-opioid interactions.
- Trial name
- NCT05143424
- Testing
- Morphine Sulfate
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cannabis Users
Intracranial Arterial Stenosis and Resin of Cannabis Use
There is an association between intracranial arterial stenosis and ischemic stroke in young adults. The aim of this study is to evaluate the prevalence of intracranial arterial stenosis in asymptomatic regular resin of cannabis…
- Trial name
- NCT02246140
- Testing
- Cerebral MRI and MRA
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Occasional (1-2 Joints Per Week) and Chronic (1-2 Joints Per Day) Cannabis Users
Study of the Relationship Between Dose-concentration-effect of Delta-9-tetrahydrocannabinol (THC) and the Ability to Drive in Chronic or Occasional Cannabis Users
Study of the effects of smoked cannabis consumption on performance on a driving simulator and reaction time. The study aims to explore the relationship between concentrations of cannabis in the blood, driving performance and…
- Trial name
- VIGICANN (NCT02061020)
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris