Clinical trials: Carbohydrates
Overweight and Obesity
Dietary Treatment Study of Fat Synthesis and Risk of Cardiovascular Disease
The purpose of this study is to find out how the amount of fat or sugar in a person's diet, or the number of meals eaten each day, affect the amount of fat that people's bodies make, the types of fats in the bloodstream, and how…
- Trial name
- NCT02075710
- Testing
- High sugar/meal feed, High sugar/nibble, High fat/meal feed
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Physical Activity
Acute Responses to Manipulating Dietary Carbohydrate Content on Free-living Physical Activity Energy Expenditure
Dietary sugar and carbohydrate intakes will be manipulated for 3 days in a randomised crossover design. All food will be provided.
- Trial name
- NCT03917810
- Testing
- Diet
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Bath
Healthy
Acute Metabolic Effects of Carbohydrate Restriction at Varying Energy Levels
This study investigates how different low-carbohydrate diets affect metabolism and hunger in overweight adults. We will measure metabolic rates and blood metabolites.
- Trial name
- NCT06387940
- Testing
- nEB Diet, followed for 36 hours, LC25 Diet, followed for 36 hours, LCEB Diet, followed for 36 hours
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Cardiovascular Disorder, Coronary Artery Disease
A Sugar-Sweetened Beverage Reduction Intervention for Native American Men
This clinical trial develops and tests a culturally-appropriate educational program (Indigenous SIPin) for reducing sugar-sweetened beverage consumption in men affiliated with Native American athletics communities.
- Conditions
- Cardiovascular Disorder, Coronary Artery Disease, Diabetes Mellitus, Obesity-Related Malignant Neoplasm
- Trial name
- NCT06029517
- Testing
- Education Intervention, Observation of Indigenous SIPin Interventon, Discussion
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Control Group, Mexico-based NSS FOPL
NSS Grocery Store Brazil
The purpose of this study is to assess the impact of non-sugar sweeteners (NSS) front-of-package labels (FOPL) on Brazilian parents' food and beverage selections for their children. The study includes three arms: 1.
- Conditions
- Control Group, Mexico-based NSS FOPL, Brazil-based NSS FOPL
- Trial name
- NCT07249008
- Testing
- Experimental : Mexico-based NSS FOPL, Experimental : Brazil-based NSS FOPL
- Where
- United States
- Volunteers
- 1,068 people, healthy volunteers welcome
- Sponsor
- George Washington University
Refractive Errors
Clinical Evaluation of Acuity 200 (Fluoroxyfocon A) RGP Contact Lens
The objective of this clinical investigation is to collect valid scientific safety and effectiveness data on the Acuity 200 (fluoroxyfocon A) Rigid Gas Permeable Contact Lens, manufactured from a newly developed rigid gas…
- Trial name
- Acuity 200 (NCT03971227)
- Testing
- Acuity 200 (Fluoroxyfocon A) contact lens, Acuity 100 (Hexafocon A) contact lens
- Where
- 3 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Acuity Polymers, Inc.
Obesity
Carbohydrate Intake and Gut Hormone Release During Exercise
It is well known that following a single session of moderate-to-high intensity exercise individuals experience a temporary suppression of hunger and a delay in the commencement of eating.
- Trial name
- NCT04019418
- Testing
- Maltodextrin (carbohydrate), Exercise, Rest
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Colorectum
Prospective Trial of Metformin - Chemoprevention Role
The goal of this clinical research study is to learn if metformin extended release (ER) can prevent colonic adenomas from becoming cancerous. Metformin ER will be compared to a placebo.
- Trial name
- NCT01550900
- Testing
- Metformin ER
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Hypoglycemia, Hypoglycemia, Reactive
Post-Prandial Carbohydrate Metabolism in Individuals With and Without Post-Bariatric Surgery Hypoglycemia (PBH)
In this study, the investigators will determine (a) whether metabolism (secretion and turnover) of glucagon is altered in patients with PBH, (b) whether this is affected by a meal, (c) whether PBH affects the ability of the body…
- Conditions
- Hypoglycemia, Hypoglycemia, Reactive, Bariatric Surgery
- Trial name
- NCT07818707
- Testing
- Glucagon for Injection (Fresenius Kabi USA), [6,6-2H2] glucose, [13C9, 15N1]-glucagon
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Obesity, Water; Lack of
Preventing Early Childhood Obesity, Part 1: Long-term Follow-up
This study extends follow up on of Native American (NA) mothers and their children (now age 3-5 years) enrolled in the 1:1 randomized controlled trial of the Family Spirit Nurture (FSN) intervention designed to prevent early…
- Conditions
- Obesity, Water; Lack of, Childhood Obesity, Feeding Behavior
- Trial name
- PECO1-LTF (NCT05424471)
- Testing
- Family Spirit Nurture (FSN), Control Group - Vehicle Safety
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Healthy
Soccer Training and Influence of Protein and Carbohydrate Ingestion on Health
The aim of the study was to examine the adaptive response to recreational soccer, conducted as small-sided games, and the effect of supplementing with either protein or carbohydrate after each training session in 10 weeks.
- Trial name
- SPC (NCT04744064)
- Testing
- Protein and carbohydrate
- Where
- Denmark
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Elite Cyclists, Elite Soccer Players
Exploring the Relationship Between the Gut Microbiome, Physical Fitness Levels and Metabolic Responses to Exercise
Gut microbiota are all microorganisms including bacteria and microscopic eukaryotes that live in the digestive tracts of humans or mammals.
- Conditions
- Elite Cyclists, Elite Soccer Players, Sedentary Behavior
- Trial name
- EXOMIC (NCT05220657)
- Testing
- Maximal incremental exercise test, Submaximal exercise test
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Metabolic Syndrome X
Controlled Clinical Study to Determine Novel Health Benefits of Cheese Consumption
To determine the effects of high cheese diets varying in carbohydrate content on markers of disease risk.
- Trial name
- NCT02918422
- Testing
- Nutritional and Dietary Manipulation
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Dietary Supplementations
Effect of Carbohydrate-protein Co-ingestion on Short-term Recovery
The purpose of this study is to determine whether the consumption of a carbohydrate, carbohydrate plus protein, or placebo sports drink during a 2-hour recovery period effectively moderates performance decrements during a…
- Trial name
- NCT04859491
- Testing
- Carbohydrate, Carbohydrate-Protein
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Erica Goldstein
Myocardial Suppression
Suppression With Empagliflozin as an Alternative To High-Fat Low-Carbohydrate Diet for Myocardial F-fluorodeoxyglucose Positron Emission Tomography (FDG-PET) Imaging
The overall objective of this study is to assess if the empagliflozin has the potential to substitute the high fat low carb (HFLC) diet for the preparation of cardiovascular FDG-PET studies.
- Trial name
- SWEET-HEART (NCT06350903)
- Testing
- Fast + High-fat low-carbohydrate diet, Fast + Empagliflozin
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Matthieu Pelletier-Galarneau, MD MSc
Grain-Like Products, Postprandial Glucose
Postprandial Glucose, Insulin and Subjective Saturation Response in Healthy Individuals
This study is a pioneering study in which the effect of the consumption of cakes produced with the addition of cereal-like products such as chia and flax seeds, which have high soluble fiber content, on blood glucose and insulin…
- Conditions
- Grain-Like Products, Postprandial Glucose, Plasma Insulin, Subjective Saturation Response
- Trial name
- NCT05358561
- Testing
- Flaxseed and Chia
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Toros University
Sweetness Liking Adaptation
Liking Adaptation to Beverages of Varying Sweetness Levels After Prolonged Exposure
This is a double-blind, controlled, parallel, randomized sensory study. The study will consist of two cohorts; habitual regular full-calorie Carbonated Soft Drink (CSD) consumers and habitual low-calorie CSD consumers.
- Trial name
- NCT04284462
- Testing
- Flavored carbonated soft drink (CSD)
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Healthy
Glucose:Fructose Versus Glucose Carbohydrate Ingestion and Endurance Performance
The primary objective is to show that multiple transportable carbohydrate ingestion is more effective in improving endurance performance compared to single transportable carbohydrate ingestion.
- Trial name
- NCT02031783
- Testing
- Mixture of glucose and fructose, glucose
- Where
- New Zealand
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Hyperbilirubinemia, Jaundice
Demographic, Metabolic, and Genomic Description of Neonates With Severe Hyperbilirubinemia
The purpose of this study is to compare the demographic, metabolic, and genomic characteristics of patients who develop severe hyperbilirubinemia to patients who never developed a significant bilirubin level.
- Trial name
- NCT00383318
- Testing
- Gene mutation sample
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Pediatrix
Carbohydrate Metabolism at Exercise
Disposal of Oral Fructose During Exercise
There is evidence that total carbohydrate oxidation during exercise is higher after ingestion of fructose:glucose mixture than after ingestion of equimolar amounts of glucose alone.
- Trial name
- NCT01128647
- Testing
- Fructose:glucose drink, glucose drink
- Where
- Switzerland
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Lausanne