Clinical trials: Carcinoma of Prostate (Disorder)
Prostate Cancer
Study of Boswellia for Urinary Toxicity in Prostate Cancer Radiotherapy
The goal of this clinical trial is to determine whether Boswellia serrata extract is effective at reducing urinary symptoms in patients undergoing radiation for prostate cancer.
- Trial name
- BURST (NCT07867158)
- Testing
- Boswellia serrata extract
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Prostate Cancer, Sexual Dysfunction
Sexual Health and Rehabilitation eClinic (SHAReClinic)
In addressing the need for effective post treatment support for men (and their partners) following treatment for prostate cancer, the investigators will employ an innovative SHAReClinic (Sexual health and Rehabilitation eClinic…
- Trial name
- NCT03396848
- Testing
- SHAReClinic
- Where
- 5 sites in Canada
- Volunteers
- 65 people
- Sponsor
- University Health Network, Toronto
Prostate Cancer
Randomized Trial of Five or Two MRI-Guided Adaptive Radiotherapy Treatments for Prostate Cancer
The study is a randomized study that compares 5 radiation therapy treatments to 2 radiation therapy treatments in men with low or intermediate-risk prostate cancer.
- Trial name
- FORT (NCT04984343)
- Testing
- Radiation Therapy
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 33 people
- Sponsor
- Weill Medical College of Cornell University
Prostate Cancer
Sulphate Accumulation in Prostate
This study evaluates whether a broccoli intervention (≥ 4 weeks) will result in differences in tissue sulphate levels in men scheduled for prostate biopsies.
- Trial name
- SAP (NCT02821728)
- Testing
- Dietary intervention, Normal diet
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Prostate Cancer
To Compare the Safety and Pharmacokinetics of PT105 With PT105R in Healthy Postmenopausal Female Volunteers
The purpose of study is to compare the safety and pharmacokinetics of PT105 with PT105R in healthy postmenopausal female volunteers
- Trial name
- NCT04783636
- Testing
- leuprorelin acetate 3.75mg
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Peptron, Inc.
Prostate Cancer Patients, Breast Cancer Patients
Cancer Survivors Program
The questionnaire for assessment of adverse events after completion of cancer treatment, which is being piloted at the Masaryk Memorial Cancer Institute, aims to detect a wide range of adverse effects early on, thus facilitating…
- Trial name
- SURV-QoL (NCT07253987)
- Testing
- active screening of adverse effects of anticancer therapy based on specific questionnaire + quality of life screening
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- Masaryk Memorial Cancer Institute
Prostate Cancer (Diagnosis), Prostate Cancer Metastatic
Evaluation of the Metastasis and Recurrence of Prostate Cancer
This study aims to use the new molecular probe 18F-PSMA for the diagnosis,staging ,recurrence monitoring and evaluation of the prostate cancer.By compared with the conventional imaging methods (whole body bone scintigraphy and…
- Conditions
- Prostate Cancer (Diagnosis), Prostate Cancer Metastatic, Prostate Cancer Recurrent, Prostate Cancer Stage
- Trial name
- NCT03507595
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Hot Flashes, Prostate Carcinoma
Vitamin B6 in Reducing Hot Flashes in Participants With Prostate Cancer Undergoing Antiandrogen Therapy
This pilot phase II trial studies how well vitamin B6 works in reducing hot flashes in participants with prostate cancer undergoing antiandrogen therapy.
- Trial name
- NCT03580499
- Testing
- Vitamin B6, Questionnaire Administration
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Adenocarcinoma of the Prostate, Hormone-resistant Prostate Cancer
Docetaxel, Prednisone, and Pasireotide in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
This phase I/II trial studies the side effects and best dose of pasireotide and to see how well it works when given together with docetaxel and prednisone in treating patients with metastatic hormone-resistant prostate cancer.
- Conditions
- Adenocarcinoma of the Prostate, Hormone-resistant Prostate Cancer, Recurrent Prostate Cancer, Stage IV Prostate Cancer
- Trial name
- NCT01468532
- Testing
- docetaxel, pasireotide, prednisone
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Cancer, Breast Cancer
Mainstreaming Genetics: Evaluation of a Digital Application to Scale and Spread Oncologist-initiated Genetic Testing
Genetic testing can alter therapy and surgical management for cancer patients and is therefore indicated as a first-line test for many newly diagnosed patients, including breast, ovarian, pancreatic, prostate and colon/GI…
- Conditions
- Cancer, Breast Cancer, Prostate Cancer, Colon Cancer
- Trial name
- NCT07387263
- Testing
- Genetics Adviser for Mainstream Care (GA-Mainstream), Mainstreaming Standard of Care
- Where
- 2 sites in Canada
- Volunteers
- 180 people
- Sponsor
- Unity Health Toronto
Prostate Cancer
Docetaxel With or Without Oblimersen in Treating Patients With Hormone-Refractory Adenocarcinoma (Cancer) of the Prostate
RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00085228
- Testing
- oblimersen sodium, docetaxel
- Where
- 16 sites in Austria, Belgium and 9 more
- Volunteers
- 116 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Hormone-Resistant Prostate Cancer, Metastatic Prostate Carcinoma
Dexamethasone Prior to Re-treatment With Enzalutamide in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Previously Treated With Enzalutamide and Docetaxel
This pilot trial studies how well dexamethasone and re-treatment with enzalutamide work in treating patients with prostate cancer that has spread to other places in the body (metastatic), does not respond to hormone therapy…
- Conditions
- Hormone-Resistant Prostate Cancer, Metastatic Prostate Carcinoma, Prostate Adenocarcinoma, Stage IV Prostate Cancer
- Trial name
- DEXTER (NCT02491411)
- Testing
- Dexamethasone, Enzalutamide, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Prostate CA
Prostate Cancer Care Disparity Analysis Project (ProGAP)
This international cross-sectional study seeks to evaluate global disparities in prostate cancer management by conducting a thorough comparison of key elements across countries categorized as low-income, lower-middle-income…
- Trial name
- NCT06612034
- Testing
- No Intervention: Observational Cohort
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ankara University
Breast Cancer, Prostate Cancer
Behavioral Weight Loss Program for Cancer Survivors in Maryland
Behavioral Weight Loss for Overweight and Obese Cancer Survivors in Maryland: A Demonstration Project
- Conditions
- Breast Cancer, Prostate Cancer, Melanoma (Skin), Endometrial Cancer
- Trial name
- ASPIRE (NCT04534309)
- Testing
- Written Weight Loss Material, Weight Loss App, Behavioral Lifestyle Weight Loss Intervention (Coaching)
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Neoplasms, Solid Tumors
Mobile Sensor Technologies to Assess General Symptomology of People With Cancer
Background: Many digital devices, such as smartphones and activity monitors, have sensors to collect and track health data. Researchers believe these devices may be able to transform the quality of clinical research and…
- Conditions
- Neoplasms, Solid Tumors, Prostate Cancer, Lung Cancer
- Trial name
- NCT04465214
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- National Cancer Institute (NCI)
Prostate Cancer Metastatic Disease, PET / CT
The Prognostic Value of PET/CT for Tumor Progression in Patients With Metastatic Hormone-sensitive Prostate Cancer
Investigators retrospectively collected data from consecutive patients treated at the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, from October 2020 to March 2024.
- Trial name
- NCT06915714
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Sun Yat-sen University
Prostatic Neoplasms
Study of Pembrolizumab (MK-3475) Plus Docetaxel Versus Placebo Plus Docetaxel in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-921/KEYNOTE-921)
The purpose of this study is to assess the efficacy and safety of the combination of pembrolizumab (MK-3475) and docetaxel in the treatment of men with metastatic castration-resistant prostate cancer (mCRPC) who have not received…
- Trial name
- NCT03834506
- Testing
- Pembrolizumab, Docetaxel, Prednisone
- Where
- 215 sites in United States, Argentina and 19 more
- Volunteers
- 1,030 people
- Sponsor
- Merck Sharp & Dohme LLC
Prostate Cancer, Localized Malignant Neoplasm
Quality of Life in Patients With Clinically Localized Prostate Cancer Treated With Radiosurgery
Quality of life data following SBRT for prostate cancer has been obtained in only a small numbers of patients. A prospective study using validated quality of life questionnaires is needed to determine outcomes after treatment…
- Trial name
- PR-PROS (NCT01766492)
- Testing
- Stereotactic Body Radiation Therapy (SBRT)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Georgetown University
Prostate Cancer
Predicting Cognitive Decline From Androgen Deprivation Therapy
Androgen Deprivation Therapy (ADT) is associated with cognitive impairment and dementia in men with prostate cancer. Pre-clinical data suggest that ADT-induced hypogonadism leads to accumulation of beta-amyloid plaques in the…
- Trial name
- ABC (NCT05820932)
- Testing
- Blood-based assay, Cognitive assessments, Quality of Life Surveys
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Head and Neck Cancer, Prostate Cancer
Application of High Resolution Diffusion-weighted MR Imaging Pulse Sequence in Head and Neck, and Prostate Cancers
Magnetic resonance imaging (MRI) is a diagnostic study that makes pictures of organs of the body using magnetic field and radio frequency pulses that can not be felt.
- Trial name
- NCT01535898
- Testing
- MRI scanner with sequence
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
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