Clinical trials: Carcinomatosis, Peritoneal
Peritoneal Surface Malignancies
The Intraoperative Physiologic Changes of Patients Under Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Cytoreductive Surgery; Prospective Observational Study
The most popular surgical treatment of peritoneal cancer is the type known as hyperthermic intraperitoneal chemoperfusion (HIPEC), a type of cytoreductive surgery for which a significantly high survival rate has been demonstrated…
- Trial name
- NCT02325648
- Testing
- HIPEC cytoreductive surgery
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Peritoneal Carcinomatosis, Peritoneal Metastases
CAR-T Intraperitoneal Infusions for CEA-Expressing Adenocarcinoma Peritoneal Metastases or Malignant Ascites (IPC)
This is an open-label, dose-escalation, phase I trial of the safety and efficacy of anti-CEA intraperitoneal CAR-T infusions for treatment in patients with CEA-expressing adenocarcinoma peritoneal metastases or malignant ascites.
- Conditions
- Peritoneal Carcinomatosis, Peritoneal Metastases, Colorectal Cancer, Gastric Cancer
- Trial name
- NCT03682744
- Testing
- anti-CEA CAR-T cells
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sorrento Therapeutics, Inc.
Safety, Healthy Volunteers
Evaluation of Healthcare Workers Safety During Pressurized Intraperitoneal Aerosol Chemotherapy
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new treatment that applies chemotherapeutic drugs into the peritoneal cavity as an aerosol. It is used to treat patient with Peritoneal Carcinomatosis (PC).
- Trial name
- PIPAC-Secure (NCT04014426)
- Testing
- Blood sample, Urinary sample
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Gastric Cancer, Gastric Adenocarcinoma
Near-infrared Imaging With Indocyanine Green for Detection of Peritoneal Metastases for Gastric Adenocarcinoma.
Peritoneal disease at initial presentation for patients with gastric adenocarcinoma (GA) is frequent, with 15-31% of patients presenting with peritoneal metastases (PM) at surgical exploration.
- Conditions
- Gastric Cancer, Gastric Adenocarcinoma, Peritoneal Carcinomatosis, Peritoneal Metastases
- Trial name
- NCT05687617
- Testing
- Indocyanine green
- Where
- 2 sites in Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Laval University
Ventral Hernias, Cytoreductive Surgery
Ventral Hernias Following Cytoreductive Surgery : Incidence, Risk Factors and Surgical Management.
Cytoreductive surgery (CRS), with or without hyperthermic intraperitoneal chemotherapy (HIPEC), is currently the standard treatment for advanced peritoneal tumors, including pseudomyxoma peritonei (PMP), colorectal, and ovarian…
- Trial name
- NCT07451483
- Where
- Belgium
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute
Peritoneal Carcinomatosis
Link of Interest and Training Model
The surgical device used to perform PIPAC procedure is commercialized by a single manufacturer under a monopoly regimen, and a formal training (economically supported by the manufacturer) is mandatory for surgeons who want to buy…
- Trial name
- NCT04341337
- Testing
- interview
- Where
- France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Centre de l'arthrose, Paris
Ovarian Cancer, Peritoneal Carcinomatosis
Imaging of Peritoneal Carcinomatosis From Ovarian Carcinoma Patients
The purpose of this study is to determine if NIF fluorescent imaging is an effective approach to detect the gross ovarian tumoral tissues and peritoneal implants in Ovarian cancer patients.
- Trial name
- OV-AP-ICG-IV (NCT01834469)
- Testing
- iv injection of ICG
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute
Pancreatic Cancer, Thyroid Cancer
Integrated Cancer Repository for Cancer Research
The iCaRe2 is a multi-institutional resource created and maintained by the Fred \& Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer…
- Conditions
- Pancreatic Cancer, Thyroid Cancer, Lung Cancer, Esophageal Cancer
- Trial name
- iCaRe2 (NCT02012699)
- Where
- 42 sites in United States
- Volunteers
- 999,999 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Postoperative Cognitive Dysfunction
Risk Factors for Early POCD in the Patients With PSM Undergoing CRS-HIPEC
Objectives to investigate the incidence and associated factors for early postoperative cognitive dysfunction in the patients with peritoneal surface malignancies undergoing cytoreductive surgery and hyperthermic intraperitoneal…
- Trial name
- NCT02462564
- Where
- China
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Wuhan University
Peritoneal Carcinomatosis
Register Study of Patients With Peritoneal Carcinomatosis Treated With PIPAC (Pressurized Intra-peritoneal Aerosol-Chemotherapy)
The study will follow up patients with peritoneal carcinomatosis from colorectal, ovarian, gastric, pancreatic cancers and primary peritoneal tumors and undergoing a diagnostic laparoscopy / laparotomy, a PIPAC as single dose or…
- Trial name
- PIPAC_01 (NCT03100708)
- Testing
- PIPAC
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Leipzig