Clinical trials: Cardiac Flow
Abnormalities, Hyperlipidemia
Study of the Effects of Blackcurrant Extract and Omega-3 Fats on the Health of the Heart and Blood Vessels
Background: Heart disease is the leading cause of death in the United States. Eating fruits and vegetables with chemicals called flavonoids may protect against heart disease and improve blood flow to the heart.
- Conditions
- Abnormalities, Hyperlipidemia, Cardiovascular Disease, Arteriosclerosis
- Trial name
- NCT02019680
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Internal Mammary Artery Syndrome, Vasodilation
Effect of Topically-applied Milrinone or Nitroglycerin on Internal Mammary Artery Free Flow
Forty-six consecutive patients undergoing elective primary coronary artery bypass grafting were enrolled. After the left IMA was harvested, free flow was measured under controlled hemodynamic conditions before any intervention…
- Trial name
- NCT06301880
- Testing
- The topical application of a vasodilator on the LIMA graft
- Where
- Syria
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Damascus University
Prone Position, Cardiac Output
Effect of Prone Position on Liver Blood Flow and Function
Recent occurrence of significant post-operative liver impairment at Nottingham University Hospitals NHS Trust has prompted investigation into whether interaction between general anaesthesia and prone positioning (lying face down)…
- Conditions
- Prone Position, Cardiac Output, Liver Circulation
- Trial name
- PLiF (NCT01781260)
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Patent Foramen Ovale, Intrapulmonary Arteriovenous Anastamosis
Is Blood Flow Through IPAVA and PFO Related to Breath-hold and SCUBA Diving-induced Pulmonary Hypertension?
In summary, the investigators propose to study elite Croatian breath-hold and SCUBA divers. The investigators will quantify breath-hold hypoxia- and SCUBA diving-induced pulmonary hypertension and right heart function to…
- Trial name
- NCT03945643
- Testing
- Sildenafil
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Athlete Heart
Interaction Between Intraventricular Flow and Cardiac Mechanics Using 3D Echocardiography in Athletes and Sedentary Subjects
Exercise-induced cardiac remodeling, known as the "athlete's heart," corresponds to morphological and functional adaptations of the left ventricle in response to prolonged physical training.
- Trial name
- CARDIO-3D (NCT07363993)
- Where
- 2 sites in France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Avignon
Cardiac
Blood Flow Restriction Resistance Exercise and Cardiac Cycle Dynamics
Blood flow restriction resistance exercise uses partial vascular occlusion of a limb during low weight resistance exercises to stimulate muscle strengthening and growth. This is commonly used during rehabilitation from an injury.
- Trial name
- NCT07344740
- Testing
- Blood flow restriction resistance exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Montclair State University
Cardiovascular Disease
Validation of Peripheral Pressure Volume Loops and Ultrasound-derived "Cardiac Power" by Comparison With Invasive Left Ventricular Pressure Volume Loops
The investigators will generate pressure-flow loops and pressure-volume loops from aortic and left ventricular pressure waveforms and Doppler (desc.
- Trial name
- NCT01750450
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Right Ventricular Dysfunction, Cardiopulmonary Diseases
Right Heart and Lung Blood Flow During Exercise (RIGHT-NET 2.0)
RIGHT-NET 2.0 is a multicenter observational study with a retrospective-prospective design that builds on the original RIGHT-NET study.
- Conditions
- Right Ventricular Dysfunction, Cardiopulmonary Diseases, Pulmonary Hypertension
- Trial name
- RIGHT-NET 2 (NCT07851610)
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- IRCCS SYNLAB SDN
Hemodynamics, Biosensors
Validation of Ballistocardiographic Biosensors and Other Hemodynamic Measures for Healthy Subjects
Ballistocardiographic (BCG) biosensors reflecting the patients' current state is established. There are few studies documenting BCG biosensors efficacy, effectiveness, and efficiency.
- Conditions
- Hemodynamics, Biosensors, Cardiac
- Trial name
- NCT04585568
- Testing
- Biosensors
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Atherosclerosis, Heart Failure, Congestive
The Role of Angiotensin Type I Receptor in the Regulation of Human Peripheral Vascular Function
The renin angiotensin system (RAS) plays an important physiological and pathophysiological role in the control of blood pressure and plasma volume.
- Conditions
- Atherosclerosis, Heart Failure, Congestive, Hypertension, Myocardial Infarction
- Trial name
- NCT00001628
- Testing
- Angiotensin II type 1 receptor antagonists
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Disease
Cerebrovascular Outcomes in Ischemic Heart Disease
This project will examine the association between (cardio)vascular disease, blood supply to the brain, and cerebrovascular endothelial activation.
- Trial name
- IHD (NCT02715661)
- Testing
- exercise
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Blood Flow Restriction Exercise, Aging
Acute Autonomic Responses During and After BFR Training
The goal of this clinical trial is to compare how the body's nervous system responds to two different types of leg exercise in young and older adults.
- Trial name
- HOLD TIGHT (NCT07722403)
- Testing
- High-Intensity Resistance Training (HIRT), Low-Intensity Resistance Training with Blood Flow Restriction (LIRT-BFR)
- Where
- Portugal
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Coronary Artery Disease
F-18 Rhodamine 6G PET Imaging for Myocardial Blood Flow
Use of novel radio-pharmaceutical Rhodamine 6G to determine myocardial blood flow
- Trial name
- NCT04528758
- Testing
- Rhodamine 6G
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Down Syndrome
Blood Flow in Individuals With Down Syndrome
This study focuses on physiological explanations of difficulties with physical activity and exercise in individuals with Down syndrome, by non-invasively examining cardiac output and the regulation of blood flow to working…
- Trial name
- NCT03590665
- Testing
- Hand grip exercise and lower body negative pressure
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Coronary Artery Disease, Heart Infarction
Effects of Personalized Training Program on Coronary Flow Reserve in Healthy Volunteers
This study investigates whether an individualized exercise program, including a personal trainer, can improve cardiovascular status quantified with ultrasound to assess coronary flow reserve and other non-invasive techniques.
- Trial name
- NCT02713724
- Testing
- physical exercise, limited physical exercise
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Renal Dialysis, Cardiovascular Diseases
Vascular Calcification, Inflammation and Coronary Flow Velocity in Hemodialysis Patients
The aim of this cross-sectional study is to determine the correlation of coronary artery calcification as measured by electron-beam computerized tomography and coronary flow reserve measured by trans-thoracic Doppler…
- Conditions
- Renal Dialysis, Cardiovascular Diseases, Atherosclerosis, Inflammation
- Trial name
- NCT00921089
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Post Opeative Pulmonary Complication
The Effect of Acapella and Incentive Spirometry on Blood Gases and Peak Expiratory Flow Rate After Coronary Artery Bypass Graft.
The goal of this clinical trial is to learn if whether the Acapella and Incentive Spirometry have effect on Blood Gas and Peak Expiratory Flow Rate among patients undergoing Coronary Artery Bypass Graft Surgery.
- Trial name
- NCT07337746
- Testing
- Incentive Spirometry therapy, Acapella therapy
- Where
- 2 sites in Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Coronary Arterial Disease (CAD), Angina (Stable)
The Effect of Sublingual Nitroglycerin on Absolute Coronary Blood Flow
The goal of this clinical trial is to investigate the effect of sublingual nitroglycerin on absolute coronary blood flow in adult patients undergoing coronary angiography.
- Trial name
- FLOW-NITRO (NCT06823843)
- Testing
- Glycerin trinitrate (GTN)
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- VZW Cardiovascular Research Center Aalst
Aortic Valve Disease, Aortic Aneurysm
Implementation of Non-size Markers Derived From 4D Flow MRI of Patients With Aortic Disease.
The aim of the investigator is to implement 4D FLOW MRI technique into a clinical setting and evaluate the blood flow pattern and wall sheer stress in patients with aortic and/or aortic valve diseases.
- Trial name
- NCT02467062
- Testing
- MRI
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Myocardial Ischemia
Multi-modality Imaging of Ischemia With 18F-FDG PET and CTA
Coronary artery disease results in narrowing of the blood vessels supplying oxygenated blood to the heart muscle. Diagnosis in patients with symptoms of chest pain is now quickly done with CT coronary angiography.
- Trial name
- NCT01520025
- Testing
- PET MPI imaging with 18F-Fluorodeoxyglucose
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation