Clinical trials: Cardiac Magnetic Resonance
Cardiomyopathy, Congenital Heart Disease
Technical Development of Cardiovascular Magnetic Resonance Imaging
This study will explore new ways of using magnetic resonance imaging (MRI) to evaluate the heart and blood vessels of patients with cardiovascular disease, including better detection of myocardial infarction (heart attack) and…
- Conditions
- Cardiomyopathy, Congenital Heart Disease, Cardiovascular Disease, Cardiac Magnetic Resonance Imaging
- Trial name
- NCT00027170
- Testing
- Siemens MRI scanner
- Where
- 2 sites in United States
- Volunteers
- 8,781 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiomyopathies, Heart Failure
31P-MRS Myocardial Energetic Phenotyping and Prognosis Across the Cardiac Disease Spectrum
The study is designed to establish a comprehensive myocardial energetic phenotype across a broad spectrum of cardiovascular diseases using phosphorus-31 magnetic resonance spectroscopy (31P-MRS).
- Trial name
- CMR-MN-31P (NCT07912086)
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Myocarditis Acute
French Registry of CMR Late Gadolinium Enhancement in Myocarditis
Acute myocarditis is a major cause of death in young adults and carries substantial morbidity, including a significant risk of progression to dilated cardiomyopathy.
- Trial name
- MYOCARDITI-LGE (NCT07394543)
- Volunteers
- 5,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Disease
Contrast-Enhanced Whole-Heart Coronary Magnetic Resonance Angiography at 3.0-T: A Multicenter Trial
The multicenter study evaluates the diagnostic performance of 3.0 T contrast-enhanced whole-heart coronary MRA in patients with suspected coronary artery disease.
- Trial name
- NCT01024478
- Where
- China
- Volunteers
- 272 people
- Sponsor
- Capital Medical University
HFpEF - Heart Failure With Preserved Ejection Fraction
Exercise Magnetic Resonance Imaging in Patients With Obesity Associated Heart Failure
To aim of the EXPOSURE study is to investigate the effects of epicardial fat on cardiac function, pericardial constraint and pulmonary artery vasodilatation using cardiac magnetic resonance (CMR) imaging at rest and during…
- Trial name
- EXPOSURE (NCT06514820)
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- University Medical Center Groningen
Cardiomyopathies
Edema and Fibrosis CMR Imaging in Cardiomyopathy
7 Tesla MRI is a new magnetic field strength that has become available at Penn for cardiovascular MRI. This new scanner has potential to improve assessment of cardiovascular disease due to its increased signal-to-noise ratio…
- Trial name
- NCT03534726
- Testing
- 7 T CMR
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Aortic Stenosis
Non-contrast 3-dimensional Cardiac Magnetic Resonance Imaging
Non-contrast enhanced cardiac MRI using 3D whole heart acquisition protocol is non-inferior to contrast enhanced CT in the assessment of aortic annulus complex for pre-TAVR imaging.
- Trial name
- NCT04496297
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- Baylor Research Institute
Myocardial Infarction, Myocardial Infarction Old
CMR Based Prediction of Ventricular Tachycardia Events in Healed Myocardial Infarction (DEVELOP-VT)
Fibrotic tissue is known to be the substrate for the appearance of scar-related reentrant ventricular arrhythmias (VA) in chronic ischemic cardiomyopathy (ICM).
- Conditions
- Myocardial Infarction, Myocardial Infarction Old, Arrhythmias, Cardiac, Ventricular Tachycardia
- Trial name
- DEVELOP-VT (NCT04599439)
- Testing
- Cardiac magnetic resonance imaging
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Centro Medico Teknon
Coronary Artery Disease
Advanced Cardiac Magnetic Resonance Imaging for Assessment of Obstructive Coronary Artery Disease: ADVOCATE-CMR
Stress perfusion cardiovascular magnetic resonance (CMR) imaging is an established non-invasive imaging test for detection of obstructive coronary artery disease (CAD).
- Trial name
- ADVOCATE-CMR (NCT06419894)
- Volunteers
- 182 people
- Sponsor
- Amsterdam UMC, location VUmc
Amyloidosis, Primary, Cardiomyopathy
Molecular Imaging of Primary Amyloid Cardiomyopathy
Cardiac amyloidosis is a major cause of early treatment-related death and poor overall survival in individuals with systemic light chain amyloidosis.
- Trial name
- MICA (NCT02641145)
- Testing
- F-18 florbetapir/C-11 acetate PET, MRI, N-13 ammonia PET
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- Brigham and Women's Hospital
Single Ventricle Defect
Cerebral Blood Flow in Single Ventricles Throughout Staged Surgical Reconstruction
This study seeks to determine cerebral blood flow changes in single ventricle patients during staged surgical reconstruction as compared with normal children.
- Trial name
- CBF (NCT02135081)
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Children's Hospital of Philadelphia
Ischemic Heart Disease
Myocardial Perfusion Magnetic Resonance Imaging Using Regadenoson
This is a pilot study to determine whether the drug regadenoson can be used during magnetic resonance imaging to assess regions of poor blood flow to the heart.
- Trial name
- NCT00881218
- Testing
- Regadenoson
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Atrial Fibrillation
Examination of Fibrillation Atria Using Magnetic Resonance Imaging and Endocardial High-density Mapping
Cather ablation of non-paroxysmal atrial fibrillation is less effective compared to paroxysmal atrial fibrillation. Therefore, new techniques have been developed, such as high-density mapping to determine areas of focal and…
- Trial name
- NCT05539313
- Testing
- High-density mapping
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- Charles University, Czech Republic
Laser Acupuncture, Meridian
The Effect of Laser Acupuncture in Different Meridians on the Autonomic Nervous System and Its Brain Mechanisms
Traditional Chinese acupuncture has a history of several thousand years. The World Health Organization has published guidelines describing the efficacy of acupuncture in the cure or relief of 64 different symptoms and conditions…
- Conditions
- Laser Acupuncture, Meridian, Heart Rate Variability, Brain Mechanism
- Trial name
- NCT05458713
- Testing
- Laser acupuncture
- Where
- Taiwan
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- China Medical University, Taiwan
Mitral Valve Stenosis
Ventricular-arterial Coupling of the Heart Among Patients With Mitral Stenosis Undergoing Percutaneous Trans-luminal Mitral Commissurotomy. Cardiac Magnetic Resonance Study
Although the incidence of rheumatic fever and its complications has declined in developed countries, the disease remains a major health problem in many developing countries.
- Trial name
- NCT06054568
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Assiut University
Atrial Flutter
Cardiovascular Magnetic Resonance-Guided Radiofrequency-Ablation for Atrial Flutter II
The purpose of this clinical study is to assess the safety and performance of the Vision-MR Ablation Catheter, the primary safety endpoint will measure the rate of serious adverse events related to the device or procedure; the…
- Trial name
- 2016-IMR (NCT03078985)
- Testing
- ablation for typical atrial flutter, catheter ablation with study device
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- University of Leipzig
Coronary Artery Disease
Ferumoxytol-enhanced Magnetic Resonance Imaging
There are no current alternatives to diagnostic contrast-requiring imaging for patients with an eGFR <30mL/min due to the association of gadolinium-based imaging modalities to nephrogenic systemic fibrosis and iodinated…
- Trial name
- NCT02954510
- Testing
- ferumoxytol
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- Brigham and Women's Hospital
Arrhythmogenic Right Ventricular Cardiomyophathy (ARVC)
Ventricular Volume as Assessed by Cardiac Magnetic Resonance
One of the many uses of cardiac magnetic resonance (CMR) is the assessment of right ventricular (RV) volumes. There are a number of congenital heart defects and acquired conditions in which management decisions are fundamentally…
- Trial name
- NCT01678040
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
STEMI
Cardiovascular Magnetic Resonance Guided Open Artery Trial for Revascularization of Late Presenting ST Elevation Myocardial Infarction
Patients with STEMI are usually treated with primary PCI in contemporary practice. However, primary PCI is currently deemed unbeneficial or potentially harmful in patients presenting late after a STEMI.
- Trial name
- CRM-OAT (NCT05374265)
- Testing
- Cardiovascular Magnetic Resonance Scan
- Where
- United Kingdom
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Pacemaker Malfunction, Implantable Defibrillator Malfunction
Cardiac Implantable Electronic Device Magnetic Resonance Imaging Registry
This is a prospective registry evaluating the safety of performing magnetic resonance (MRI) scans on patients who have cardiac implanted electronic devices (CIEDs).
- Trial name
- CIED-MRI (NCT02459379)
- Testing
- MRI Scan
- Sponsor
- NYU Langone Health