Clinical trials: Cardiac Magnetic Resonance Imaging
Cardiac Magnetic Resonance Imaging in Non Ischemic Cardiomyopathy
Cardiac Magnetic Resonance in Non Ischemic Cardiomyopathy
Cardiac magnetic resonance imaging has been established as a promising three dimensional imaging modality with the ability to assess cardiac morphology, ventricular function, perfusion, viability and imaging characteristics of…
- Trial name
- NCT03638271
- Testing
- Cardiac magnetic resonance imaging
- Volunteers
- 50 people
- Sponsor
- Reham Sameeh
Microvascular Obstruction (MVO), Multivessel Coronary Artery Disease
For Patients With Myocardial Infarction and Multiple Vessel: Testing if Ultrasound (UFR) Can Guide All Needed Treatment in One Procedure, Avoiding a Return Hospital Visit for a Second Operation.
Brief Summary The Purpose of the Study : The purpose of this study is to find a safe and reliable "one-stop" solution for treating heart attack patients who have multiple blocked arteries.
- Conditions
- Microvascular Obstruction (MVO), Multivessel Coronary Artery Disease, ACS (Acute Coronary Syndrome), ST Elevation Myocardial Infarction (STEMI)
- Trial name
- ACT-EVOLVE (NCT07264881)
- Testing
- IVUS-based Fractional Flow Reserve (UFR), Invasive Coronary Physiology Measurement (FFR/RFR/IMR), Cardiac Magnetic Resonance (CMR)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Anzhen Hospital
Dilated Cardiomyopathy, Left Ventricular Systolic Dysfunction
Cardiovascular Magnetic Resonance GUIDEd Insertion of Implantable Cardiac Defibrillator in Dilated CardioMyopathy
CMR GUIDE DCM is a randomized controlled trial with a registry for non-randomized patients. Patients enrolled will have non-ischemic cardiomyopathy (NICM) with mild to severe Left Ventricular (LV) systolic dysfunction with…
- Conditions
- Dilated Cardiomyopathy, Left Ventricular Systolic Dysfunction, Fibrosis Myocardial
- Trial name
- CMR GUIDE DCM (NCT03993730)
- Testing
- ICD, ILR
- Volunteers
- 1,880 people
- Sponsor
- Flinders University
Myocardial Ischemia, Exercise
Exercise-induced Changes in Cardiac Function & Morphology
Until now it has been assumed that regular endurance training has a positive influence on cardiac function and that the positive effect increases with increasing intensity.
- Conditions
- Myocardial Ischemia, Exercise, Myocardial Contraction, Myocardial Stunning
- Trial name
- NCT01179802
- Testing
- Strenuous Endurance exercise
- Where
- Switzerland
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Congenital Heart Disease
3D Cine Cardiovascular Magnetic Resonance
Conventional CMR is based on breath-hold 2D cine image acquisitions which are sequentially acquired in different imaging planes.
- Trial name
- NCT03583775
- Testing
- Cardiovascular Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Boston Children's Hospital
Myocardial Infarction, Percutaneous Coronary Intervention
China-Administration of Nicorandil Group（CHANGE）
We compared the infarct size in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) treated by nicorandil before and after the reperfusion with those standard…
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, Nicorandil
- Trial name
- NCT03445728
- Testing
- Nicorandil
- Where
- China
- Volunteers
- 238 people
- Sponsor
- Chinese PLA General Hospital
Left Ventricular Dysfunction
Phosphorous Magnetic Resonance Spectroscopy of Heart
Heart needs constant supply of energy to continue working. Phosphorus magnetic resonance spectroscopy allows us to measure energy produced in the heart.
- Trial name
- NCT01110395
- Testing
- MR Spectroscopy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Washington University School of Medicine
Coronary Atherosclerosis, Coronary Artery Disease
Natural History of Coronary Atherosclerosis in Real-World Stable Chest Pain Patients Underwent Computed Tomography Angiography in Comparison With Invasive Multimodality Imaging
In a prospective international multicenter observational study, 1080 stable chest pain patients (REALITY Advanced registry of CCTA patients) with the suspected chronic coronary syndrome will be enrolled.
- Conditions
- Coronary Atherosclerosis, Coronary Artery Disease, Contrast-induced Nephropathy, Cerebrovascular Disease
- Trial name
- REALITY (NCT02440646)
- Testing
- Coronary computed tomography angiography, Quantitative coronary angiography, intravascular imaging with percutaneous intervention
- Where
- 4 sites in Estonia, Netherlands and 1 more
- Volunteers
- 1,080 people
- Sponsor
- Central Clinical Hospital of the Russian Academy of Sciences
Congenital Coronary Artery Abnormality
Italian Registry of Cardiovascular Magnetic Resonance on Congenital Anomalies of the Coronary Arteries (ITACA-Registry)
Italian registry of coronary artery abnormalities diagnosed utilizing cardiac magnetic resonance imaging.
- Trial name
- ITACA (NCT04691791)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- ITAB - Institute for Advanced Biomedical Technologies
Magnetic Resonance Angiography, Contrast Media
Improving the Concentration of MR Contrast in the Arteries
In Contrast-Enhanced Magnetic Resonance Angiography (CE-MRA) a contrast agent is injected into an arm vein using a programmable medical device called a power injector.
- Trial name
- NCT02155218
- Testing
- Standard Injection Rate, Patient Tailored Injection Rate, gadolinium contrast
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Washington
Endothelial Dysfunction, Myocardial Perfusion Abnormalities
Cardiac Magnetic Resonance Imaging for Detecting Endothelial Dysfunction
The goal of this research study is to demonstrate that Cardiac Perfusion MRI with Vasomotor Stress may serve as a non-invasive and less risky imaging technique for detecting non-obstructive perfusion deficits and/or abnormalities…
- Conditions
- Endothelial Dysfunction, Myocardial Perfusion Abnormalities, Cardiac MRI Perfusion With Vasomotor Stress, Diabetes
- Trial name
- NCT00808535
- Testing
- Cardiac Perfusion MRI w Vasomotor Stress
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Acute Myocardial Infarction
The Effects of Facilitated Percutaeous Coronary Intervention in Acute Myocardial Infarction
The purpose of this study to investigate whether the administration of high-dose tirofiban before primary PCI could reduce myocardial infarct size, using analysis of contrast-enhanced magnetic resonance imaging.
- Trial name
- NCT00611169
- Testing
- tirofiban
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Tricuspid Valve Insufficiency
MRE Evaluation of Liver Stiffness After Tricuspid Valvular Repair
The purpose of this study is to look at liver stiffness with a MRI sequence called Magnetic Resonance Elastography (MRE). The study will let the investigators know whether the subject's liver is normal or has increased stiffness.
- Trial name
- NCT03166488
- Testing
- MRI
- Sponsor
- Mayo Clinic
Pacemaker Malfunction, Implantable Defibrillator Malfunction
Cardiac Implantable Electronic Device Magnetic Resonance Imaging Registry
This is a prospective registry evaluating the safety of performing magnetic resonance (MRI) scans on patients who have cardiac implanted electronic devices (CIEDs).
- Trial name
- CIED-MRI (NCT02459379)
- Testing
- MRI Scan
- Sponsor
- NYU Langone Health
Congenital Heart Disease, Pulmonary Hypertension
MRI and Computational Simulation Cardiology Study
The purpose of this study is to (1) quantify cardiovascular anatomy and physiology using magnetic resonance imaging under both resting and exercise conditions in patients who have congenital heart disease and in age-matched…
- Trial name
- NCT03149341
- Testing
- Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Stanford University
Lung Cancer, Ventricular Failure
Right Ventricular Inflammation After Lung Resection
The purpose of this study is explore the impact of lung cancer surgery on inflammation and function of the right side of the heart.
- Trial name
- NCT03523611
- Testing
- Lung Resection
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Glasgow
Coronary Artery Disease
Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)
Participants being evaluated for suspected or known Coronary artery Disease (CAD) based on signs and/or symptoms, will be invited to participate in the study.
- Trial name
- GadaCAD 1 (NCT01890421)
- Testing
- Gadobutrol (Gadovist, Gadavist, BAY86-4875)
- Where
- 23 sites in United States, France and 5 more
- Volunteers
- 426 people
- Sponsor
- Bayer
Ventricular Ejection Fraction
DMP115 in Patients With an Ejection Fraction Between 25%-40% to Evaluate the Use of Contrast Echocardiography to Assess Heart Function
The purpose of this clinical research study is to demonstrate the ability of Definity® enhanced versus unenhanced cardiac ultrasound to improve the accuracy and reproducibility of left ventricular ejection fraction (EF) when…
- Trial name
- NCT00401687
- Testing
- Definity® Vial for (Perflutren Lipid Microsphere) Injectable Suspension
- Where
- 10 sites in United States
- Volunteers
- 131 people
- Sponsor
- Lantheus Medical Imaging
Mitral Regurgitation
Multimodality Imaging Assessment of the Severity of Mitral Regurgitation
To investigate to assess the severity of mitral regurgitation by multimodality imaging.
- Trial name
- NCT06266858
- Testing
- rehydration, UCG, CMR
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Heart Failure, Left Ventricular Systolic Dysfunction
CarDiac MagnEtic Resonance for Primary Prevention Implantable CardioVerter DebrillAtor ThErapy: an International Registry (DERIVATE)
The DERIVATE study was conceived to integrate the information resulted from clinical data, transthoracic echocardiography, and cardiac magnetic resonance (CMR) imaging to provide a more reliable risk stratification in patients…
- Trial name
- DERIVATE (NCT03352648)
- Where
- 29 sites in United States, Belgium and 4 more
- Volunteers
- 4,000 people
- Sponsor
- Gianluca Pontone, MD, PhD