Clinical trials: Cardiac Patients
Exercise, Cardiac Myosins
Changes in Adiponectin and Cardiovascular Disease Risk Factors in Overweight Patients
This study aimed to determine if eight-weeks of exercise-based cardiac rehabilitation could improve adiponectin and cardiovascular disease risk factors in overweight coronary heart disease patients.
- Conditions
- Exercise, Cardiac Myosins, Patients
- Trial name
- NCT02882672
- Testing
- Experimental, Control
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Isfahan
Acute Heart Failure
Study to Evaluate the Effectiveness of High Dose Statin Loading in Acute Heart Failure Patients
This is a prospective, single-center, randomized, controlled, open-label, pilot study to evaluate the effectiveness of high dose statin loading in acute heart failure patients.
- Trial name
- NCT01127945
- Testing
- statin
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Early Recovery in Elderly Patients, Cognitive Function
Effects of Sevoflurane vs Desflurane on Early Recovery and Cognitive Function in Elderly Patients Undergoing Scheduled Non-Cardiac Surgery
The goal of this clinical study is to compare the effects of desflurane versus sevoflurane on early postoperative recovery and cognitive function in elderly patients (aged 60 years and older, ASA I-III) undergoing elective…
- Trial name
- NCT07289945
- Testing
- Sevoflurane, Desflurane
- Where
- Tunisia
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Hopital Charles Nicolle
Dyslipidemias
Effect of Combined Lipid-lowering Therapy on Atherosclerotic Plaque Vulnerability in Patients With ACS
The study is prospective, open-label, randomized, single-center study involving patients admitted on an emergency basis with an acute coronary syndrome (ACS) clinic who underwent PCI of an infarct-related artery (IRA) and had…
- Trial name
- Combi-LLT ACS (NCT05624658)
- Testing
- Combined Lipid-lowering Therapy
- Where
- Russia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Samara Regional Cardiology Dispensary
Peep Titration in Lung Protective Ventilation
Lung Protective Ventilation and Driving Pressure Guided PEEP Titration in CABG Surgery
Our aim in this study is to compare fixed and individualized PEEP (driving pressure guided ) application for intraoperative lung protective ventilation in patients undergoing on-pump CABG surgery.
- Trial name
- NCT07044089
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Type 2 Diabetes Mellitus With Circulatory Complciation
Association of Carbamylated HDL and CAD in T2DM Patients
This is an observational cross-sectional study aimed at investigating the alterations of the carbamylated-HDL levels in T2DM patients, and comparing the concentration of carbamylated-HDL between the T2DM patients with CAD and…
- Trial name
- NCT04390711
- Testing
- High density lipoprotein isolation, detection and in-vitro study.
- Where
- China
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Coronary Artery Disease (CAD)
Endothelial Progenitor Cells and Nitric Oxide in Cardiac Rehabilitation Program Participants
This study will measure blood levels of endothelial progenitor cells (EPCs) and nitric oxide (NO) in patients with coronary artery disease (CAD) who are participating in a 3-month cardiac rehabilitation program at Suburban…
- Trial name
- NCT00308633
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Ectasia
Effect of Diltiazem on Coronary Artery Ectasia
Coronary artery ectasia (CAE) has been defined as localized or diffuse dilatation of epicardial coronary arteries more than 1.5 fold of adjacent normal segments.
- Trial name
- NCT02024919
- Testing
- intracoronary administration of diltiazem, intracoronary injection of 5 mL saline
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara University
Atrial Fibrillation; Stroke Prevention
Stroke Prevention in Atrial Fibrillation Patients Between 2004 and 2020
Prevention of thromboembolic complications is an important part in the management of patients with atrial fibrillation (AF). European and American guidelines recommend the use of non-vitamin K antagonist oral anticoagulants…
- Trial name
- NCT04686045
- Testing
- observational study
- Where
- 2 sites in Poland
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Jan Kochanowski University
Diabetic Ketoacidosis, Heart Disease, Ischemic
Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning.
- Conditions
- Diabetic Ketoacidosis, Heart Disease, Ischemic, Stroke, GastroIntestinal Bleeding
- Trial name
- NCT04977011
- Testing
- relaxing music
- Where
- Taiwan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Surgery (Cardiac)
Kolcaba's Comfort Theory on the Comfort Levels of Patients Undergoing Open Heart Valve Surgery
It is planned to determine the effect of comfort theory-based nursing care on the comfort and pain levels of patients undergoing open heart valve surgery.
- Trial name
- NCT06769945
- Testing
- Nursing Care Based on Kolcaba's Comfort Theory
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Cardiac Arrest, Post Traumatic Stress Syndrome
Family-Authored ICU Diaries to Reduce Fear in Patients Experiencing a Cardiac Arrest (FAID Fear)
The present study will: Aim 1: Enroll 15 family members of CA patients to (a) pilot recruitment procedures, (b) estimate retention, and (c) assess acceptability of study procedures.
- Trial name
- FAID Fear (NCT05144477)
- Testing
- FAID Fear Intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Columbia University
Impact of Health Information Exchange on Patient Care, (Focus on Diabetes, Asthma, Hypertension, CHF, COPD, CAD,
Evaluation of a Regional Electronic Health Information Exchange's Clinical Health Record
The Shared Health CHR™ (Clinical Health Record) offers point-of-care clinical reporting and decision support based primarily on patient claims data aggregated across various health care settings, and is one example of the types…
- Conditions
- Impact of Health Information Exchange on Patient Care, (Focus on Diabetes, Asthma, Hypertension, CHF, COPD, CAD,, Gastroenteritis, Seizures, and Bacterial Pneumonia)
- Trial name
- NCT00978744
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Healthy, Hypertrophic Cardiomyopathy
Investigation Into the Use of Ultrasound Technique in the Evaluation of Heart Disease
The human heart is divided into four chambers. One of the four chambers, the left ventricle, is the chamber mainly responsible for pumping blood out of the heart into the circulation.
- Conditions
- Healthy, Hypertrophic Cardiomyopathy, Left Ventricular Hypertrophy
- Trial name
- NCT00001632
- Where
- United States
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma, COPD
Exhaled Breath Metabolomic Biomarkers in the Acutely Breathless Patient
An acute study carried out across three acute admissions units within Leicestershire. The study is aimed at discovery and validation of volatile organic compounds (VOCs) in exhaled breath.
- Conditions
- Asthma, COPD, Heart Failure, Community-acquired Pneumonia
- Trial name
- EMBER (NCT03672994)
- Where
- United Kingdom
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Death, Sudden, Cardiac, Arrythmia
Monitoring of Arrhythmias in Patients Treated With Antipsychotics
Antipsychotics may be associated to life-threatening arrhythmias and sudden cardiac death. This is the fist study to estimated the arrhythmic burden using long-term monitoring by implantable loop recorder in patients treated with…
- Conditions
- Death, Sudden, Cardiac, Arrythmia, Antipsychotics and Neuroleptics Toxicity
- Trial name
- MAPP (NCT04575103)
- Testing
- Antipsychotic
- Where
- 18 sites in Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Dental Anxiety, Dental Anxiety in Children
Virtual Reality Storytelling Versus Storybook Reading for Dental Anxiety in Children
Many children feel anxious before dental treatment. This study compares two ways of helping children feel calmer while waiting for their dental visit: watching a dental story through virtual reality (VR) glasses, or listening to…
- Conditions
- Dental Anxiety, Dental Anxiety in Children, Preoperative Anxiety
- Trial name
- NCT07863661
- Testing
- Virtual Reality Storytelling, Traditional Storybook Reading
- Where
- Saudi Arabia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Hereditary Angioedema
Autonomic Nervous System Profile in Hereditary Angioedema
The goal of this study is to compare the autonomic nervous system control of patients with hereditary angioedema to healthy individuals.
- Trial name
- ANS-HAE (NCT06408805)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Surgery
Effectiveness of Animation-Based Education Given to Elderly Patients Undergoing Coronary Artery Bypass Graft Surgery
It was conducted to measure the effectiveness of animation-based training given to elderly patients who will undergo coronary artery bypass graft surgery on the patients' pain, fear, anxiety and self-care management.
- Trial name
- NCT06928025
- Testing
- Preoperative Education
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ayşegül Sena Pirgaip Yavuz
Long QT Syndrome
Metabolism of Patients With Genetically Caused Cardiac Arrhythmia
Loss-of-function mutations in voltage-gated potassium channels cause long QT syndrome (LQTS) due to a prolonged cardiac repolarisation phase.
- Trial name
- NCT02775513
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
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