Clinical trials: Cardiac Surgical Patients
Open Heart Surgery
The Effect of Rapid Relaxation Exercise and Cold Application on Pain, Anxiety, and Satisfaction Before Chest Tube Removal
A chest tube is inserted to drain air, fluid, or blood from the pleural space and is vital for restoring respiratory function in the postoperative period.
- Trial name
- NCT07248085
- Testing
- Cold Application, Rapid Relaxation Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people
- Sponsor
- Ataturk University
Hypotension, Bradycardia
Effects of Ondansetron on Hemodynamic Changes After Spinal Anesthesia in Geriatric Urologic Surgery
Spinal anesthesia is frequently used in urologic surgery in geriatric patients; however, it may cause significant hemodynamic changes such as hypotension and bradycardia.
- Conditions
- Hypotension, Bradycardia, Hypotension During Surgery, Spinal Anesthesia Induced Hemodynamic Change
- Trial name
- NCT07551219
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ankara City Hospital Bilkent
Cardiac Infarct, Cardiac Valve Disease
Frailty, Physical Capacity and Lung Function in Postoperative Cardiac Surgery Patients
The goal of this observational and prospective study is to investigate changes in physical performance, lung function, and respiratory and peripheral muscle strength in patients during the postoperative period following coronary…
- Conditions
- Cardiac Infarct, Cardiac Valve Disease, Fragility, Physical Disability
- Trial name
- NCT06247358
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo General Hospital
Diabetes Mellitus, Type 2
Effects of Exercise Therapy on Ventricular and Endothelial Function in Patients After Coronary Artery Bypass Surgery
The purpose of this study was (1) to compare the peak exercise capacity and left ventricular diastolic function between patients with and without diabetes and (2) to investigate the interrelation among peak oxygen consumption…
- Trial name
- NCT01990638
- Testing
- exercise capacity test
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- National Taiwan University Hospital
Postoperative Neurocognitive Dysfunction, Postoperative Neurocognitive Disorder
The Role of Neuroinflammation on Neurocognitive Outcome in Cardiac Surgery
RATIONALE: Postoperative cognitive changes are common after cardiac surgery and can be categorised into three main types: postoperative delirium (POD), delayed neurocognitive recovery (DNCR) and postoperative neurocognitive…
- Conditions
- Postoperative Neurocognitive Dysfunction, Postoperative Neurocognitive Disorder, Cardiac Surgery, Major Surgery Under General Anesthesia
- Trial name
- INOCS (NCT07200726)
- Testing
- Observational study design - no intervention
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Ziekenhuis Oost-Limburg
Atrial Fibrillation, Left Atrial Appendage Absent
Can Patients With Atrial Fibrillation Safely Discontinue Anticoagulant Therapy After Cardiac Surgery? (ATLAAC)
Left atrial appendage (LAA) closure has become a frequent addition to oral anticoagulation in patients with atrial fibrillation who undergo cardiac surgery.
- Conditions
- Atrial Fibrillation, Left Atrial Appendage Absent, Anticoagulant Adverse Reaction
- Trial name
- NCT06401616
- Testing
- OAC will be discontinued for the duration of the trial
- Where
- 6 sites in Denmark
- Volunteers
- 1,220 people
- Sponsor
- Odense University Hospital
Diastolic Dysfunction
Perioperative Measurements of Diastolic Function in Cardiac Surgery
This observational clinical trial will investigate the following perioperative indices relating to cardiac surgery: 1. The significance of measurements involving left heart relaxation (LV diastolic function) and its relation to…
- Trial name
- NCT02285309
- Testing
- Cardiac Surgery and enoximone
- Volunteers
- 100 people
- Sponsor
- University College, London
Pulmonary Hypertension, Mitral Valve Surgery
PDEI Following Mitral Valve Surgery in Patients With Pulmonary Hypertension
A randomized, placebo controlled, single center clinical trial for evaluation of efficacy and safety of Sildenafil administration in the cardiac ICU following Mitral Valve (MV) Surgery in patients with pre-operative Significant…
- Trial name
- NCT02378649
- Testing
- Sildenafil
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Dr. Robert Klempfner Heart Rehabilitation Institute
Cognitive Impairment (CI)
Post-operative Functional Disability in Unrecognized Cognitive Impairment (POF) Study
This is a prospective multicenter cohort study, which will determine the prevalence of preoperative cognitive impairment (CI) using the Modified Telephone Interview for Cognitive Status (TICS-M), Eight-items interview to…
- Trial name
- NCT04850833
- Where
- 2 sites in Canada
- Volunteers
- 390 people
- Sponsor
- University Health Network, Toronto
Postoperative Complications, Patient Care Team
Extended Care in High-Risk Surgical Patient (EXCARE) Pathway in High-risk Surgical Population
High risk surgical patients are subject to complications that impact rehabilitation time, overall mortality and costs. This project proposes the creation of a post-surgery care pathway called Extended Care in High-Risk Surgical…
- Trial name
- EXCARE (NCT04187664)
- Testing
- Postoperative Monitoring, High-sensitivity cardiac troponin testing
- Where
- Brazil
- Volunteers
- 1,720 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pain, Pain Management Following Cardiopulmonary Bypass Surgery
Addition of Dexmedetomidine to Ropivacaine in Bilateral Erector Spinae Plane Block in Patients Undergoing Coronary Artery Bypass Surgery
Coronary artery bypass surgery (CABG), typically performed through a median sternotomy, causes significant postoperative pain. Managing this pain effectively while reducing reliance on opioids is essential, as opioids can lead to…
- Conditions
- Pain, Pain Management Following Cardiopulmonary Bypass Surgery, Erector Spinae Plane Block
- Trial name
- NCT06981949
- Testing
- Dexmedetomidine, Ropivacaine
- Volunteers
- 110 people
- Sponsor
- Lebanese American University
Anxiety, Chest Tube Removal
Virtual Reality-Based Breathing Yoga Before Chest Tube Removal After Cardiac Surgery
This randomized controlled trial was conducted to evaluate the effect of virtual reality-based breathing yoga applied before chest tube removal on pain and anxiety in patients after cardiac surgery.
- Conditions
- Anxiety, Chest Tube Removal, Pain After Surgery
- Trial name
- NCT07794709
- Testing
- Virtual Reality-Based Breathing Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Sennur Kula Şahin
Pain, Postoperative
Analgesic Efficacy of Bilateral US Guided TTPB vs ESPB in Pediatric Patients Undergoing Corrective Cardiac Surgeries
Corrective cardiac surgeries include a bundle of major surgeries that take place in pediatric patients and require imperative perioperative pain control; hence, the art of healing starts from trying to diminish or abolish pain.
- Trial name
- NCT05559684
- Testing
- Erector spinae plane block, Transversus thoracis plane block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Vasoplegia Syndrome
Effects of Vitamin C on Shock Duration and Microcirculation in Patients With Vasoplegia Syndrome After Cardiac Surgery
This pilot study intends to observe the effect of intravenous vitamin C on the prognosis and sublingual microcirculation in patients with vasoplegia syndrome after cardiac surgery through a prospective randomized controlled study…
- Trial name
- NCT06723626
- Testing
- Vit C, Standard Preparation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Southeast University, China
Coronary Artery Bypass Grafting, Surgical Treatment for Heart Valve Diseases
China Cardiovascular Surgery Registry
China Cardiovascular Surgery Registry (CCSR) Study is a national database for coronary artery bypass grafting (CABG) and valve surgery performed in 87 hospitals with cardiovascular surgery volume > 100 per year.
- Trial name
- CCSR (NCT02400125)
- Where
- China
- Volunteers
- 90,000 people
- Sponsor
- China National Center for Cardiovascular Diseases
Patients Undergoing Cardiothoracic Surgery
Limiting IV Chloride to Reduce AKI After Cardiac Surgery
This primary aim of this study is to test the impact of a strategy of perioperative chloride-restriction through intravenous (IV) fluid therapy on the incidence of acute kidney injury after cardiac surgery.
- Trial name
- LICRA (NCT02020538)
- Testing
- Low-chloride perioperative intravenous fluid strategy, High-chloride perioperative intravenous fluid strategy
- Where
- Australia
- Volunteers
- 1,298 people
- Sponsor
- Bayside Health
Cardiac Surgery, Atrial Fibrillation
Spironolactone and Perioperative Atrial Fibrillation Occurrence in Cardiac Surgery Patients.
Study hypothesis : Pre-operative aldosterone receptor blockade may reduce post-operative atrial fibrillation (POAF) occurrence within 5 days after coronary artery bypass graft surgery (CABG) ± aortic valve replacement (AVR)…
- Conditions
- Cardiac Surgery, Atrial Fibrillation, Aldosterone Blockade
- Trial name
- ALDOCURE (NCT03551548)
- Testing
- Spironolactone 25mg
- Where
- 2 sites in France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Caen
Erector Spinae Plane Block
Continuous ESP Block in Patients Undergoing CABG Surgery.
This study addresses articles and studies related to the erector spinae plane (ESP) block and its technique, advantages and disadvantages, applicability, among others.
- Trial name
- NCT07666178
- Testing
- Ropivacaine, Standard Postoperative Analgesics
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- Instituto do Coracao
Postoperative Complications, Electrocardiogram: Electrical Alternans
Microvolt T-wave Alternans in Cardiac Surgery Patients
The purpose of this study is to measure MTWA in the patients undergoing cardiac surgery and to investigate the relation between MTWA and adverse clinical outcomes.
- Trial name
- NCT03201289
- Where
- South Korea
- Volunteers
- 224 people
- Sponsor
- Seoul National University Hospital
Cardiac Surgery
Benefits of a Comprehensive Patient Education on Oral Anticoagulant Compared to Conventional Hospital Education
To meet the wishes of the Ministry of Health, the division of Cardiology University Hospital of Clermont Ferrand, combining the cardiology and cardiac surgery department, has developed since January 2009, a therapeutic education…
- Trial name
- EDUCA (NCT01699282)
- Testing
- VKA (antivitamin K) education, conventional hospital education
- Where
- France
- Volunteers
- 186 people
- Sponsor
- University Hospital, Clermont-Ferrand
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