Clinical trials: Cardiopulmonary Resuscitation (CPR)
Cardiopulmonary Resuscitation
Optimizing Integration of CPR Feedback Technology With CPR Coaching for Cardiac Arrest
There is significant data showing that the quality of CPR performed is quite poor. Recent studies have shown that when real-time visual corrective feedback is available to CPR providers, quality (compression depth and rate)…
- Trial name
- NCT03204162
- Testing
- CPR Coaching
- Where
- 5 sites in United States, Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
Cardiopulmonary Arrest, Cardiac Arrest
Trial of Vasopressin and Epinephrine to Epinephrine Only for In-Hospital Pediatric Cardiopulmonary Resuscitation
Cardiac arrest has a very poor prognosis, especially with prolonged efforts at resuscitation, and unfortunately, survivors are often severely neurologically impaired.
- Trial name
- Vasopressin (NCT00628550)
- Testing
- Vasopressin, Epinephrine
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of Texas Southwestern Medical Center
Cardiac Arrest
In-hospital Cardiopulmonary Resuscitation With Balloon Occlusion of the Descending Aorta
This study will test if a sustained Return of Spontaneous Circulation (ROSC) in patients with cardiac arrest is more frequent when patients receive advanced cardiac life support (ACLS) alone or when they receive ACLS plus a…
- Trial name
- CPReboa (NCT07434726)
- Testing
- resuscitative endovascular occlusion of the aorta (REBOA), Advanced Cardiac Life Support (ACLS)
- Where
- Switzerland
- Volunteers
- 98 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Circulatory Failure, Cardiac Arrest
Evaluation of Efficacy of the Prototype RPC (Rapid Pulse Confirmation) Device in Detecting Return of Pulsatile Flow in Patients Preparing to Separate From CPB (Cardiopulmonary Bypass)
Effective chest compressions are essential to survival in an arrest patient receiving CPR (cardiopulmonary resuscitation). A challenge in providing effective chest compressions is frequent interruption of compressions.
- Trial name
- NCT04526249
- Testing
- rapid pulse confirmation device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Michael Kyle Ritchie
Heart; Arrest, Newborn, Birth Asphyxia
Does Higher (100% Oxygen) Versus Lower (21% Oxygen) During CC+SI During CPR of Asphyxiated Newborns Improve Time to ROSC
When newborn babies are born without a heartbeat the clinical team has to provide breathing and chest compressions (what is call cardiopulmonary resuscitation) to the newborn baby.
- Conditions
- Heart; Arrest, Newborn, Birth Asphyxia, Bradycardia Neonatal
- Trial name
- SURV1VE-O2 (NCT03902652)
- Testing
- Intervention (21% oxygen during CC+SI), Intervention (100% oxygen during CC+SI)
- Where
- Canada
- Sponsor
- University of Alberta
Pancreas and Hepatobiliary Cancer Patients
Cardiopulmonary Resuscitation (CPR) Video to Enhance Advance Care Planning in Advanced Upper Gastrointestinal Cancer Patients
Advance care planning involves thinking about choices if the patient becomes sick, and is important for everyone. It does not matter if the patients are ill or healthy.
- Trial name
- NCT01105806
- Testing
- (CPR) video and questionnaires, cardiopulmonary resuscitation (CPR) narrative script and questionnaires
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Basic Life Support Training Course, Cardiopulmonary Resuscitation (CPR)
Serious Game vs Traditional BLS Training in Adolescents
This randomized controlled trial aimed to compare the effects of a serious video game and traditional training on adolescents' basic life support (BLS) knowledge and skills.
- Trial name
- NCT07286708
- Testing
- Lifesaver Video Game CPR Training, Traditional Instructor-Led CPR Training
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people
- Sponsor
- Burcu SELVI CALSIKAN
ExtraCorporeal Membrane Oxygenation (ECMO), Cardiac Arrest
Plasma Biomarkers and Platelet Morphology of Extracorporeal CardioPulmonary Resuscitation
Extracorporeal cardiopulmonary resuscitation (ECPR) constitutes a pivotal emergency intervention for cardiac arrest (CA) patients.
- Trial name
- ECPR (NCT07113769)
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Central China Fuwai Hospital of Zhengzhou University
Cardiac Arrest, Out-Of-Hospital
Prehospital ECPR in Moravia Silesia Region
Cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrest (OHCA) in specific cases could be improved by Extracorporeal membrane oxygenation (ECMO; ECPR).
- Trial name
- 01-Pain (NCT07041086)
- Testing
- Extracorporeal membrane oxygenation (ECMO)
- Where
- 2 sites in Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Out-Of-Hospital Cardiac Arrest, Advanced Cardiac Life Support
Cardiac Arrest and Ventilation Method
Comparison of Manual Ventilation and Automatic Mechanical Ventilation during CPR, Pilot \& Feasibility Study (CAVE-I trial)
- Conditions
- Out-Of-Hospital Cardiac Arrest, Advanced Cardiac Life Support, Ventilation
- Trial name
- NCT05550454
- Testing
- Automatic Mechanical Ventilation, Manual Ventilation
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Heart Arrest
Resuscitation Outcomes Consortium (ROC) Prehospital Resuscitation Using an Impedance Valve
The purpose of this study is to look at two different treatments during a cardiac arrest that occurs outside of the hospital and whether either or both treatments will increase the number of people who live to hospital discharge.
- Trial name
- NCT00394706
- Testing
- Impedance Threshold Device (ITD), Analyze early, Analyze later
- Where
- 9 sites in United States, Canada
- Volunteers
- 11,738 people
- Sponsor
- University of Washington
Heart Arrest
Dispatcher-Assisted Resuscitation Trial (DART)
The purpose of this study is to determine whether dispatcher-assisted CPR instructions with compressions and ventilations versus dispatcher-assisted CPR instructions with compressions only improves survival from out-of-hospital…
- Trial name
- NCT00219687
- Testing
- dispatcher-assisted CPR with compressions & ventilations, dispatcher-assisted CPR instructions with compressions only
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 5,494 people
- Sponsor
- Public Health - Seattle and King County
Cardiopulmonary Resuscitation, Cardiac Arrest
Physical Workload Identify in Chest Compression Position Using Surface Electromyogram
The chest compression depth decreases over time after starting continuous chest compression due to the rescuers' fatigue. The investigators hypothesized that the frequency parameters from surface electromyogram from each muscle…
- Trial name
- NCT02088879
- Testing
- chest compression with kneeling position, chest compression with standing position
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hanyang University
Cardiorespiratory Arrest, Cardiopulmonary Arrest With Successful Resuscitation
Effectiveness of Online Training in Cardiopulmonary Resuscitation Maneuvers for a Network of Volunteers.
Background: Cardiorespiratory arrest (CPA) occurs when there is a cessation of cardiac mechanical activity, typically diagnosed by the absence of consciousness, pulse, and breathing.
- Trial name
- EFORCP (NCT06275984)
- Testing
- online CPR-AED training
- Where
- Spain
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Pulmonary Hypertension, Bronchopulmonary Dysplasia
Study of the Effect of Four Methods of Cardiopulmonary Resuscitation Instruction on Psychosocial Response of Parents With Infants at Risk of Sudden Death
OBJECTIVES: I. Describe the psychosocial response of parents and caretakers who learn cardiopulmonary resuscitation (CPR) techniques for infants at high risk for respiratory or cardiac arrest. II.
- Conditions
- Pulmonary Hypertension, Bronchopulmonary Dysplasia, Respiratory Distress Syndrome
- Trial name
- NCT00004805
- Testing
- CPR instruction
- Volunteers
- 500 people
- Sponsor
- National Center for Research Resources (NCRR)
Out-of-Hospital Cardiac Arrest
Combining Performance of Call EMS and Simultaneous Chest Compressions in a Lone Rescuer CPR
Investigators designed the novel combining technique that rescuer start the chest compression with one hand during calling for help to the Emergency Medical System (EMS) via a cell phone with another hand when he witnessed the…
- Trial name
- NCT02646046
- Testing
- Combi lone-CPR, Conventional lone-CPR
- Where
- South Korea
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Cardiac Arrest
Evaluation of Effectiveness of Virtual Reality-based Dispatcher Assisted Cardiopulmonary Resuscitation Training
This study aims to compare the effect of conventional cardiopulmonary resuscitation (CPR) training and CPR training with added virtual reality (VR) on trainee self-efficacy.
- Trial name
- NCT06226246
- Testing
- HEROS VR CPR training program, Conventional HEROS CPR training program
- Where
- South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Cardiac Arrest
Aminophylline in Bradyasystolic Cardiac Arrest
The purpose of this study is to evaluate the effect of aminophylline in patients with out-of-hospital bradyasystolic cardiac arrest.
- Trial name
- NCT00312273
- Testing
- Aminophylline (250mg IV +/- a second dose of 250mg IV)
- Where
- Canada
- Volunteers
- 966 people
- Sponsor
- Vancouver General Hospital
Cardiac Arrest, Out-Of-Hospital
Brain Oxygenation During Cardiopulmonary Resuscitation
The study is aimed to assess (a) the incidence of hyperoxia at the point of return of spontaneous circulation (ROSC) and (b) the role of arterial blood oxygen partial pressure to brain oxygenation during out-of-hospital cardiac…
- Trial name
- NCT03464123
- Testing
- Standard cardiopulmonary resuscitation
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Helsinki University Central Hospital
Cardiopulmonary Arrest
REBOA in Nontraumatic OHCA
The investigators propose a multicenter randomized controlled trial in South Korea and Taiwan to observe the clinical effects of REBOA on nontraumatic out-of-hospital-cardiac-arrest (OHCA) patients.
- Trial name
- REBOA (NCT06031623)
- Testing
- REBOA
- Where
- South Korea
- Volunteers
- 234 people
- Sponsor
- Seoul National University Hospital