Clinical trials: Cardiopulmonary Resuscitations
Cardiac Arrest (CA)
Hand vs. Foot Chest Compressions in Simulation
Cardiopulmonary resuscitation (CPR) is essential in the management of cardiorespiratory arrest (CA) to improve survival rates. High-quality chest compressions are the primary intervention to maintain circulation and oxygenation…
- Trial name
- NCT07074080
- Testing
- Performing chest compressions on a mannequin using the foot, Performance of standard chest compressions with the upper limbs.
- Where
- Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Mental Stress
Task Focusing Strategy During a Simulated Cardiopulmonary Resuscitation
This is a prospective randomized controlled study. The aim of this study is to 1. describe the stress patterns experienced during a CPR situation; 2.
- Trial name
- NCT01645566
- Testing
- instruction
- Where
- Switzerland
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Cardiopulmonary Resuscitation, Basic Life Support
Digital and Face-to-face Basic Life Support Training for Teacher Candidates
Today, circulatory system and heart diseases, especially hypertension, are increasing day by day, and sudden and unexpected cardiac arrests due to these diseases are more common.
- Trial name
- NCT05522166
- Testing
- Digital Stories and Face-to-face Basic Life Support Trainings
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Cardiac Arrest, Fibrillation, Ventricular
Early Double Sequential Defibrillation in Out-of-hospital Cardiac Arrest
Some of the patients affected by Out-of-hospital cardiac arrest (OHCA) with ventricular fibrillation (VF)/ventricular tachycardia (VT) do not respond to initial defibrillation.
- Conditions
- Cardiac Arrest, Fibrillation, Ventricular, Sudden Cardiac Death, Sudden Cardiac Arrest
- Trial name
- DOUBLE-D (NCT06447805)
- Testing
- Double Sequential Defibrillation (DSD), Standard defibrillation
- Where
- 3 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Emergencies
Research on Key Technologies and System Optimization of Early Warning and Resuscitation of Cardiac Arrest
Studies have shown that early prevention and warning of cardiac arrest, rapid implementation of high-quality cardiopulmonary resuscitation, and strengthening of organ function protection after resuscitation are the keys to…
- Trial name
- NCT04955288
- Testing
- Aortic balloon assisted resuscitation, Traditional cardiopulmonary resuscitation, Esophageal cooling
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Out-of-Hospital Cardiac Arrest
Combining Performance of Call EMS and Simultaneous Chest Compressions in a Lone Rescuer CPR
Investigators designed the novel combining technique that rescuer start the chest compression with one hand during calling for help to the Emergency Medical System (EMS) via a cell phone with another hand when he witnessed the…
- Trial name
- NCT02646046
- Testing
- Combi lone-CPR, Conventional lone-CPR
- Where
- South Korea
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Heart Arrest, Heart Arrest, Out-Of-Hospital
An Educational Program to Improve Cardiac Arrest Diagnostic Accuracy of Ambulance Telecommunicators
Cardiac arrest is the number one cause of death in Canada. It is often the first symptom of cardiac disease for the victims. Eighty-five percent of victims collapse in their own home.
- Conditions
- Heart Arrest, Heart Arrest, Out-Of-Hospital, Cardiac Arrest, Death, Sudden, Cardiac
- Trial name
- NCT03894059
- Testing
- Educational Intervention
- Where
- Canada
- Volunteers
- 12,224 people
- Sponsor
- Ottawa Hospital Research Institute
Cardiopulmonary Arrest, Resuscitation
Augmented Reality to Support Cardiopulmonary Resuscitation
A prospective, multicenter, randomized clinical trial in two tertiary pediatric emergency department. It will assess, amongst pediatric healthcare teams, whether the use of augmented reality supportive devices improves adherence…
- Conditions
- Cardiopulmonary Arrest, Resuscitation, Pediatric
- Trial name
- NCT06376643
- Testing
- Augmented reality supportive tool, Conventional method (AHA pocket reference card)
- Where
- 2 sites in Canada, Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Johan Siebert, MD
Inhospital Cardiac Arrest
Neurological Outcomes After In-Hospital Cardiac Arrest
Little is known about the long-term neurological outcomes after in-hospital cardiac arrest (IHCA). It is also not known whether withdrawal of life-sustaining measures will influence rates of survivors with poor neurological…
- Trial name
- NO-IHCA (NCT03006484)
- Testing
- No intervention
- Where
- South Korea
- Volunteers
- 322 people
- Sponsor
- Asan Medical Center
Heart Arrest, Ventricular Fibrillation
Observational and Diagnostical Study on Transient Allostatic Responses of Thyroid Function After Cardiopulmonary Resuscitation
Time-limited adaptive responses of thyroid function are common in the critically ill. About 70% of all patients treated on intensive care units develop a so-called non-thyroidal illness syndrome (NTIS) or TACITUS (thyroid…
- Conditions
- Heart Arrest, Ventricular Fibrillation, Ventricular Flutter, Ventricular Tachycardia
- Trial name
- Thyro-CPR (NCT04392258)
- Testing
- TSH determination, FT4 determination, FT3 determination
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Ruhr University of Bochum
Cardiac Arrest (CA)
Ventilation During CPR and Return of Spontaneous Circulation
During cardiopulmonary resuscitation (CPR), rescue breaths help move air into the lungs, but the amount of air delivered is rarely measured.
- Trial name
- NCT07834294
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rush University Medical Center
Out-Of-Hospital Cardiac Arrest, Advanced Cardiac Life Support
Cardiac Arrest and Ventilation Method
Comparison of Manual Ventilation and Automatic Mechanical Ventilation during CPR, Pilot \& Feasibility Study (CAVE-I trial)
- Conditions
- Out-Of-Hospital Cardiac Arrest, Advanced Cardiac Life Support, Ventilation
- Trial name
- NCT05550454
- Testing
- Automatic Mechanical Ventilation, Manual Ventilation
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Out of Hospital Cardiac Arrest, Computed Tomography
Timing for Computed Tomography and Post-Resuscitation Care on Short-Term Outcomes in Out-of-Hospital Cardiac Arrest
This retrospective multicenter study investigates the association between the timing of computed tomography (CT) scans and short-term outcomes in adult non-traumatic out-of-hospital cardiac arrest (OHCA) patients who achieved…
- Trial name
- NCT06936917
- Volunteers
- 5,000 people
- Sponsor
- National Taiwan University Hospital
Cardiopulmonary Resuscitation, Simulation Training
The Effect of Attention Distractor on the Quality of Chest Compression
The investigators plan to investigate the effect of attention distractor on the quality of chest compression during cardiopulmonary resuscitation.
- Trial name
- NCT03124290
- Testing
- paced auditory serial addition test (PASAT)
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Inje University
Cardiac Event, Sudden Cardiac Death
To Determine Optimal Time for Delivering Electrical Shocks to Cardiac Arrest Patients
In this study, we are comparing the difference in outcomes between patients who were given shocks to the heart, during the upstroke of cardiopulmonary resuscitation (CPR) and before CPR is started.
- Conditions
- Cardiac Event, Sudden Cardiac Death, Death, Ventricular Fibrillation
- Trial name
- NCT01665755
- Testing
- Upstroke Compression Defibrillation, Precompression Defibrillation
- Where
- Singapore
- Volunteers
- 180 people
- Sponsor
- Singapore General Hospital
Cardiac Arrest (CA)
V-CPR Under Special Circumstances
Out-of-hospital cardiac arrest (OHCA) remains a major cause of death globally, with bystander CPR rates varying widely (13-82%) despite public health efforts.
- Trial name
- NCT07101510
- Testing
- sV-CPR, V-CPR, T-CPR
- Where
- Hungary
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Cardiopulmonary Resuscitation, Basic Cardiac Life Support
Tilt Cardiopulmonary Resuscitation With a Feedback Device
According to the European Resuscitation Council (ERC) Guidelines for patient to a depth of approximately 5-6 cm on a firm and flat surface when possible.
- Trial name
- NCT02175563
- Testing
- Audiovisual feedback from smartphone based app
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hanyang University
Quality of Cardio-pulmonary Resuscitation
Manikin Study on Different Protocols of CPR (MANI-CPR)
The aim of the study is to verify whether the inclusion of breaks of different frequency and duration during the hands-only cardio-pulmonary resuscitation (CPR) could increase chest compressions quality during an 8-minutes…
- Trial name
- MANI-CPR (NCT02632500)
- Testing
- Quality of chest compressions
- Where
- 8 sites in Italy, Switzerland
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- Pavia nel Cuore
Cardiopulmonary Arrest, Cardiopulmonary Resuscitation
Plethysmographic Waveform for Monitoring the Quality of Cardiopulmonary Resuscitation
Cardiopulmonary resuscitation(CPR) is the key to success for high-quality early cardiopulmonary resuscitation, and its success in the restoration of spontaneous circulation (ROSC), therefore, monitoring the quality of…
- Conditions
- Cardiopulmonary Arrest, Cardiopulmonary Resuscitation, Return of Spontaneous Circulation, Pulse Oximeter Plethysmographic Waveform
- Trial name
- PWMQC (NCT01987245)
- Where
- China
- Volunteers
- 617 people
- Sponsor
- Jun Xu
Cardiopulmonary Arrest, Cardiopulmonary Resuscitation
Compression Feedback for Patients With In-hospital Cardiac Arrest
A prospective, randomized, controlled, parallel study was conducted in patients undergoing resuscitation with chest compression for in-hospital cardiac arrest (IHCA) in the mixed medical-surgical ICU's of 8 academic tertiary care…
- Trial name
- CFA (NCT02845011)
- Testing
- Audiovisual compression feedback, Standard Manual Chest Compression
- Volunteers
- 900 people
- Sponsor
- Baqiyatallah Medical Sciences University