Clinical trials: Cardiovascular Care
Hospitalization Rate, Mortality Rate
Efficacy of Multi-disciplinary Integrated Post-acute Care in Patients Admission for Heart Failure
Background: Clinical heart failure patients always suffering from (1) worsen symptoms such as decreased activity tolerance, end-to-end breathing and excessive body fluid volume; (2) high medical expenses results from…
- Conditions
- Hospitalization Rate, Mortality Rate, Functional Recovery, Left Ventricle Ejection Fraction
- Trial name
- NCT04638179
- Testing
- Not intervention.Use retrospective case contrl study.
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Palliative Care, Heart Failure
Advanced Heart Care at Home
End-of-life (EOL) care for heart failure (HF) patients includes high healthcare utilization and costs, in part due to the lack of integration of optimal HF management and home-based palliative care.
- Conditions
- Palliative Care, Heart Failure, Health Care Utilization, Quality Improvement
- Trial name
- AHCAH (NCT03724695)
- Testing
- Clinician nudge or opt out approach for AHCAH liaison visit
- Where
- United States
- Volunteers
- 709 people
- Sponsor
- University of Pennsylvania
Diabetes Mellitus, Type 2 Diabetes Mellitus
Improving Diabetes in Primary Care (IMPACT)
The goal of our research program is to successfully translate empirical knowledge regarding diabetes treatment and management into sustainable clinical practice.
- Conditions
- Diabetes Mellitus, Type 2 Diabetes Mellitus, Hypertension
- Trial name
- NCT00108927
- Testing
- TRANSLATE
- Where
- United States
- Volunteers
- 6,000 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Obstructive Pulmonary Disease, Heart Failure
Well Being and Rehabilitation in Chronically Ill Patients: Structured Patient Education and Physical Exercise
This study addresses self management and maintenance of health through evaluation of a program of patient education in combination with physical training and with a structured follow-up.
- Conditions
- Chronic Obstructive Pulmonary Disease, Heart Failure, Stroke
- Trial name
- NCT00989456
- Testing
- Self management education programme, exercise only
- Where
- 5 sites in Norway
- Volunteers
- 54 people
- Sponsor
- Norwegian University of Science and Technology
Essential Hypertension, Sleep Quality
Sleep Hygiene Education and Blood Pressure Control in Essential Hypertension in Primary Care
This randomized controlled trial evaluated the effect of a brief sleep hygiene education program on sleep quality and blood pressure in adults with essential hypertension attending a family practice center in southern Türkiye.
- Conditions
- Essential Hypertension, Sleep Quality, Primary Care
- Trial name
- NCT07257237
- Testing
- Sleep hygiene education program
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people
- Sponsor
- Ozturk Gurer Tutu, MD
Spinal Stenosis
Acupuncture for Lumbar Spinal Stenosis
Acupuncture is widely used to manage chronic low back pain. Mounting evidence suggests the beneficial effects of acupuncture for mitigating chronic low back pain with acceptable minor adverse events.
- Trial name
- NCT01987622
- Testing
- Acupuncture, Usual care
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Korean Medicine Hospital of Pusan National University
Aortic Valve Stenosis
Study to Improve Outcomes in Aortic Stenosis
Multi-centre, multi-national, observational, prospective registry in four central full access centres in Germany (2), France (1) and the United Kingdom (1) and up to two satellites per hub (smaller hospitals / office based…
- Trial name
- NCT03112629
- Where
- 2 sites in France, Germany
- Volunteers
- 791 people
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Acute Coronary Syndrome, Troponin
Pragmatic Randomised Trial of the ESC 0/1 Versus 0/3 Hour Troponin Pathway
The primary objective of this study is to assess the feasibility and impact of implementing the ESC 0-1 hour high sensitive troponin pathway in clinical practice and with specific reference to the 0-3 hour pathway currently in…
- Conditions
- Acute Coronary Syndrome, Troponin, Chest Pain, Point-of-care Systems
- Trial name
- MACROS2 (NCT05322395)
- Testing
- ESC 0/1 hour troponin pathway
- Where
- United Kingdom
- Volunteers
- 3,536 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Heart Failure, Patient Empowerment
Remote Patient Monitoring for Patients With Heart Failure in France
The goal of this multicenter observational longitudinal cohort study is to evaluate the ability of a Remote Patient Monitoring (RPM) program to prevent cardiac decompensation by detecting weak signals of decompensation early in…
- Conditions
- Heart Failure, Patient Empowerment, Cardiac Failure
- Trial name
- TELESAT-HF (NCT06312501)
- Testing
- Satelia®Cardio, Conventional care
- Where
- France
- Volunteers
- 20,000 people
- Sponsor
- Satelia
Dysfunction, Left Ventricular
Ultrasound and Left Ventricular Systolic Function
The aim of this study is to evaluate, in an intensive care unit, the reproducibility between two non-cardiologists operators and a cardiologist expert in echocardiogram, of the Simpson method and of the calculation of GLS for the…
- Trial name
- EFESE (NCT02381756)
- Testing
- Ultrasound
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Hypertension
Tailored to You (TTY) Pilot Study
The purpose of this research study is to use a test called impedance cardiography (ICG) to provide more information about how to improve the control of blood pressure.
- Trial name
- NCT05141175
- Testing
- Hypertension medication algorithm, Impedance Cardiography
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Duke University
Subarachnoid Hemorrhage
Impact of Early Mobilization on SAH Patients Physiological Parameters
The aim of the study is to evaluate the physiological response to out-of-bed mobilization in patients admitted to the intensive care unit for subarachnoid hemorrhage.
- Trial name
- MOBALPAH (NCT06286683)
- Testing
- lung ultrasound, Transcranial Doppler, near-infrared spectroscopy (NIRS)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Congenital Heart Disease (CHD), Artifical Intelligence
AI-Assisted Versus Independent Heart Sound Screening for Congenital Heart Disease in Children
This is a prospective, school-based, cluster-randomized controlled trial conducted in Qinghai Province, China. The study will evaluate whether artificial intelligence (AI) can help primary care physicians identify congenital…
- Conditions
- Congenital Heart Disease (CHD), Artifical Intelligence, Screening, Cardiac Auscultation
- Trial name
- NCT07830251
- Testing
- AI-Assisted Cardiac Auscultation
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Kun Sun
Coronary Artery Disease, Complication of Coronary Artery Bypass Graft
Negative Pressure Dressing After Saphenous Vein Harvest
This study will test the effectiveness of negative pressure wound therapy (using the VAC Prevena device, KCI Canada Inc.) applied to the saphenous vein harvest site after Coronary Artery Bypass Grafting (CABG).
- Conditions
- Coronary Artery Disease, Complication of Coronary Artery Bypass Graft, Wound Complication
- Trial name
- NCT01698372
- Testing
- Prevena device (Group A)
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of Calgary
Varicose Ulcer
Study of Individualized Wound Prevention Instruction to Prevent Venous Ulcer Development
The purpose of this study is to determine whether individualized wound prevention instructions will lengthen the ulcer-free period in veterans with recently healed venous ulcers.
- Trial name
- NCT00727701
- Testing
- Aftercare summary
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- US Department of Veterans Affairs
Stroke, Amputation
Statistical Parametric Mapping (SPM 1D) for Stroke and Trans-tibial Amputation
Gait analysis is commonly performed in clinical practice. However, it is complex and requires an understanding of the activation of muscles in lower limbs, trunk, and upper limbs in a specific spatiotemporal pattern and the…
- Trial name
- NCT04169594
- Testing
- 3D Gait Analysis with Statistical Parametric Mapping
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Tan Tock Seng Hospital
Shock, Fluid Overload
Evaluating Fluid Responsiveness in ICU Patients Using VTI and Trendelenburg Positioning
Fluid administration is a commonly performed in the ICU for critically ill patients. However, it can lead to complications such as fluid overload, pulmonary edema, and increased mortality in some patients.
- Conditions
- Shock, Fluid Overload, Cardiac Output, Low
- Trial name
- TREND-US (NCT06418022)
- Testing
- Trendelenburg positioning VTI
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Lenox Hill Hospital
Pregnancy Related, Hypertension
Testing Implementation Strategies to Support Clinic Fidelity to an Outpatient Hypertension Bundle
The goal of this clinical trial is to test an approach to improve care for pregnant and post-partum patients with high blood pressure.
- Trial name
- ACHIEVE (NCT06002165)
- Testing
- Usual Care, ACHIEVE Multi-component Implementation Strategy
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- University of North Carolina, Chapel Hill
Heart Failure, ICUAW
Intensive Care Unit-acquired Heart Failure in Critically Ill: the ICU-HF Study
Critically ill patients in intensive care units (ICUs) are exposed to a wide range of complications that can affect long-term morbidity and mortality.
- Trial name
- ICU-HF (NCT07094425)
- Testing
- transthoracic echocardiography
- Where
- 2 sites in Austria, Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany
Subarachnoid Hemorrhage (SAH)
ICP Versus Intracranial Compliance Guided Management in SAH
The purpose of this study is to determine whether treatment guided also by ICP mean wave amplitude improves outcome compared to international standard care in patients with SAH.
- Trial name
- NCT00248690
- Testing
- ICP mean wave amplitude
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital