Clinical trials: Cardiovascular Condition
Neuropathy, Stroke
Effect of Spasticity on Tibial Nerve Entrapment
Stroke is the most common cause of mortality and is one of the most common causes of morbidity in the world. Polyneuropathies and entrapment neuropathies are known as the complications of stroke
- Trial name
- NCT06092190
- Testing
- EMG
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- October 6 University
Risk Reduction Behavior, Diabetes Mellitus, Type 2
Corazon de la Familia (Heart of the Family)
The Corazón de la Familia study is a randomized controlled trial to examine the effects of a novel family-focused lifestyle modification intervention to reduce risk for type 2 diabetes and cardiovascular disease (CVD) among…
- Conditions
- Risk Reduction Behavior, Diabetes Mellitus, Type 2, Cardiovascular Diseases
- Trial name
- NCT03196024
- Testing
- Family-focused intervention arm, Individual-focused intervention arm
- Where
- United States
- Volunteers
- 526 people, healthy volunteers welcome
- Sponsor
- Gia Mudd
Diabetic Retinopathy, Type 2 Diabetes
Enriched Eggs for Retina Health in Type 2 Diabetes
Diabetes mellitus has been declared a major public health issue. Among the complications of the disease, retinopathy can have a significant impact on mobility and quality of life for individuals living with diabetes.
- Trial name
- NCT04496817
- Testing
- Docosahexaenoic Acid and Lutein Enriched Eggs, Regular Eggs
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Coronary Heart Disease
Innovation Research of Differentiation and Treatment Methods Based on CHD Phlegm and Blood Stasis Syndrome
Coronary heart disease is still the major cause of death in China. Chinese medicine plays more and more important role in CHD prevention and treatment. Phlegm and blood stasis are its major pathological basis.
- Trial name
- NCT02967718
- Where
- China
- Volunteers
- 13,000 people, healthy volunteers welcome
- Sponsor
- Jingqing Hu
Atherosclerosis
PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis (Volunteer - BioD and Safety Study)
This study is designed to assess the safety, biodistribution and dosimetry of the novel atherosclerotic imaging PET radiotracer, Cu[64]-25%-CANF-Comb.
- Trial name
- NCT02498379
- Testing
- Cu[64]-25%CANF-Comb
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Stroke
Stroke COunseling for Risk REduction
The purpose of this study is to test the efficacy of the Stroke Counseling for Risk Reduction (SCORRE) intervention in increasing accuracy of perceived stroke risk and promoting lifestyle behavior change to reduce stroke risk in…
- Trial name
- SCORRE (NCT03076125)
- Testing
- SCORRE, Attention-Control Activity
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Hypertension
The Effects of Scalp Block With Bupivacaine Versus Levobupivacaine
Ninety American Society of Anesthesiologists (ASA) Physical Status classification system I-II patients were recruited for a randomised, placebo-controlled, double-blind study and were randomly divided into three groups to receive…
- Trial name
- NCT02497040
- Testing
- Levobupivacaine, Bupivacaine
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Uludag University
Sick Sinus Syndrome
The Role of Angiotensinogen Gene Polymorphism in the Pathogenesis of Non-familial Sick Sinus Syndrome
Evidence has been documented for the close relationship between the arrhythmia pathogenesis and the gene expression in renin-angiotensin system.
- Trial name
- NCT01310920
- Testing
- observation
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Pulmonary Embolism, Venous Thromboembolism
Rivaroxaban in Elderly Chinese Venous Thromboembolism Patients
There's no unified recommendation in clinical practice regarding adjusting dosages for different patient types, especially when adverse events occur.
- Conditions
- Pulmonary Embolism, Venous Thromboembolism, Anticoagulant-induced Bleeding
- Trial name
- NCT06194617
- Testing
- Direct oral anticoagulant
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Heart Failure
Application of Nanotechnology and Chemical Sensors for Diagnosis of Decompensated Heart Failure by Respiratory Samples
Application of Nanotechnology and Chemical Sensors for Diagnosis of Decompensated Heart Failure by Respiratory Samples. Breath testing, which links specific volatile molecular biomarkers in exhaled breath to medical conditions…
- Trial name
- NCT03083717
- Testing
- Collection of breath samples, followed by analysis of exhaled breath using nanomaterial-based sensors (NaNose)
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Mental Health, Mindfulness
Perspective on Thoughts and Feelings as a Predictor of Psychological Well-being in Daily Life, in a Community Sample
This project examines the psychological construct of decentering - a mindfulness-related construct marked by an observer perspective on one's ongoing mental processes.
- Trial name
- NCT03336710
- Where
- United States
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Pulmnary Hypertension
Detecting Pulmonary Hypertension With the Eko CORE 500 Digital Stethoscope
This prospective, observational study will evaluate whether synchronized heart sound (phonocardiogram, PCG) and three-lead electrocardiogram (ECG) recordings (entered as separate interventions in PRS, though collected together in…
- Trial name
- EKO-PH (NCT07136623)
- Testing
- Eko CORE 500 phonocardiogram (PCG) recording, Eko CORE 500 three-lead electrocardiogram (ECG) recording
- Where
- 2 sites in United States
- Volunteers
- 1,513 people, healthy volunteers welcome
- Sponsor
- Eko Devices, Inc.
Telangiectasia, Rosacea
Treatment of Dilated Blood Vessels on the Cheeks With a New Yellow Laser and a Traditional Green Laser
The goal is to compare a novel yellow laser, based on semiconductor technology, with traditional green laser, in the treatment of cheek telangiectasias.
- Trial name
- NCT03472859
- Testing
- PHOTOLASE, KTP
- Where
- Finland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Stress Reaction; Acute
Racial Discrimination and Stress Response
The goal of this study is to learn about whether ethnic minority adolescents' racial discrimination experience is related to dysregulated biological responses to subtle racism, and how the relationship may be attenuated or…
- Trial name
- NCT05820659
- Testing
- peer rejection task, conversation about peer rejection, and impossible puzzle task
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Western Kentucky University
Hyperlipidemia, Metabolic Syndrome X
Low Fat Plant-Based Supplemented Diet Effects on Risk Factors for Chronic Non-communicable Diseases
The effect of a diet free from animal-sourced nutrients on a variety of risk factors for chronic non-communicable diseases in weight reduction programs is not well established.
- Trial name
- LFPBDS2 (NCT02905448)
- Testing
- Low fat plant-based nutrition
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Barbara Jakše s.p.
Obesity, Heart Failure, Diastolic
Improving Metabolic Health in Patients With Diastolic Dysfunction
The purpose of this study is to determine whether 1 year of supervised exercise training in obese individuals at high risk for developing HF, incorporating high intensity interval training (HIIT) two to three times per week in…
- Conditions
- Obesity, Heart Failure, Diastolic, Metabolic Syndrome
- Trial name
- MTG (NCT03448185)
- Testing
- High intensity exercise, Omega-3 fish oil, Yoga
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hypertension
Comparative Bioavailability Study of Eplerenone 50 mg Tablets Under Fasting Conditions
The purpose of this study is to demonstrate the relative bioequivalence of Eplerenone 50 mg ER Tablets under fasting conditions.
- Trial name
- NCT00865176
- Testing
- Eplerenone 50 mg Tablets Sandoz Inc., USA, Inspra 50 mg Tablets GD Searle LLC, USA
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sandoz
Stroke, Hypertension
Family at Risk Study
Atherosclerotic cardiovascular disease (ASCVD) risk factors include hypertension as a key risk factor, as well as hyperlipidemia, diabetes, smoking, obesity, diet, inactivity, family history and age.
- Trial name
- FAR (NCT04607876)
- Testing
- Technological Facilitator, Standard of Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Chronic Periodontitis, Cardiovascular Diseases
NSPT On Vitronectin And Fetuin-A Levels In Patients With Periodontitis And Coronary Artery Disease
Periodontitis is a chronic inflammatory disease mainly caused by the oral microbial biofilm. It involves the periodontal supporting tissues mainly features gum inflammation, alveolar bone resorption, periodontal pocket formation…
- Conditions
- Chronic Periodontitis, Cardiovascular Diseases, Periodontal Inflammation
- Trial name
- NCT05663476
- Testing
- Non Surgical Periodontal Therapy
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Normal Healthy Volunteers Without Chronic Medical Conditions, Coronary Artery Disease
3D PET Myocardial Blood Flow and Rb82 Infusion Profiles
The investigators seek to test bolus infusions (50ml/min) vs. slow infusions (20 ml/min) of Rb-82 on metrics of coronary blood flow assessed on a modern 3D PET/CT.
- Conditions
- Normal Healthy Volunteers Without Chronic Medical Conditions, Coronary Artery Disease, Cardiac Risk Factors, Myocardial Infarction
- Trial name
- NCT05286593
- Testing
- Slow Infusion of Rubidium-82
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
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