Clinical trials: Cardiovascular Condition
Diabetes Mellitus, Type II, Overweight and Obesity
Microclinic Social Induction Pilot Intervention for Diabetes and Obesity Management in Qatar
The purpose of the study is to pilot-phase test the effectiveness of the microclinic social induction model and its effects on behavioral and metabolic outcomes in different levels of social and familial relationships in Qatar.
- Conditions
- Diabetes Mellitus, Type II, Overweight and Obesity, Hypertension, Behavioral Lifestyle Change
- Trial name
- NCT02175537
- Testing
- Microclinic Social Induction Diabetes and Obesity Program
- Where
- Qatar
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Microclinic International
Heart Diseases, Cardiac Conduction Defect
Developing Methods for Reconstructing Electrical Heart Activity
Non-invasive reconstruction of electrical heart activity can yield important scientific and clinical insights in cardiac rhythm disorders.
- Trial name
- NCT03947021
- Testing
- Computed tomography (CT) scan, Body-surface potential mapping
- Where
- Netherlands
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy, Inflammatory Disease
Genetic Variants and Regulation of Specialized Pro-resolving Mediator
Inflammation is the way that the body reacts against infection, injury or illness. An uncontrolled inflammatory response can lead to the development of inflammatory diseases, such as rheumatoid arthritis and cardiovascular…
- Conditions
- Healthy, Inflammatory Disease, Cardiovascular Diseases
- Trial name
- NCT04698291
- Testing
- Blood Donation
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Normal and Abnormal Cardiovascular Physiology
Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging
Background: Magnetic resonance imaging (MRI) is an important non-invasive tool to study and diagnose cardiovascular disease. MRI scanners use strong magnetic fields and radio waves to create pictures of body organs.
- Trial name
- NCT03581318
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Abdominal Surgery, Hypertension
The Effect of Laughter Yoga on Nurses' Perceived Stress Burnout and Life Satisfaction During the Pandemic Period
This study aimed to determine the effects of laughter yoga on the perceived stress, burnout and life satisfaction of nurses working actively during the pandemic period.
- Conditions
- Abdominal Surgery, Hypertension, Done Laughter Yoga Before, Epilepsy
- Trial name
- NCT05317091
- Testing
- Laughter yoga practiced
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Health Literacy, Communication
Health Literacy and Cardiovascular Knowledge Workshop in Women From Disadvantaged Communities
The current health literacy (HL) pilot intervention was designed through focus groups with women in low socio-economic status (SES) communities. The primary HL issue identified was communication challenges at doctors' visits.
- Trial name
- NCT03203018
- Testing
- Interactive workshop based on community specific needs
- Where
- Israel
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Pregnancy, Weight Gain
Cardiovascular Health in Postpartum Women Diagnosed With Excessive Gestational Weight Gain
The investigators will test the efficacy of a tailored behavioral lifestyle modification program to support cardiovascular health in postpartum women with excessive gestational weight gain.
- Trial name
- NCT02142452
- Testing
- behavioral intervention, Usual Prenatal Care
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Stanford University
Posterior Fossa Hemorrhage, Lung Cancer
Pilot Study of Model Based Iterative Reconstruction Using 64-Slice
This study is being performed to confirm that the new technique, Model-Based Iterative Reconstruction (MBIR) with reduced radiation dose can deliver equivalent image quality for CT scans compared to current techniques (Filtered…
- Conditions
- Posterior Fossa Hemorrhage, Lung Cancer, Flank Pain, Urolithiasis
- Trial name
- MBIR (NCT01431378)
- Where
- 3 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Migraine Headache, PFO - Patent Foramen Ovale
Migraine With Aura and Patent Foramen Ovale: Identification of Biomarkers to Select Patients In Whom Intervention Would Be Beneficial (MANET)
This is a multicenter prospective observational study aimed to asses whether a specific prothrombotic platelet phenotype can discern migraine patients with PFO (patent forame ovale) - related symptoms from patients with…
- Trial name
- MANET (NCT06046508)
- Testing
- blood samples collection
- Where
- 3 sites in Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centro Cardiologico Monzino
Obesity
Glycemic Index and CVD: a Crossover Feeding Study
This study will compare the physiological effects of two isoenergetic, nutrient-controlled diets that differ in glycemic index. The diets will be studied in obese adults in a 10-day crossover feeding trial.
- Trial name
- NCT00141076
- Testing
- low vs high glycemic index diet
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Bone Tumor, Cancer of Bone
Endoprosthesis Metal Toxicity Study
The purpose of this research is to investigate whether patients who previously had endoprosthesis surgery experience memory, thinking, or heart problems. It will also help determine how often these problems occur.
- Conditions
- Bone Tumor, Cancer of Bone, Heart Diseases, Cognitive Impairment
- Trial name
- NCT04755140
- Testing
- Questionnaires, Interviews, Blood Test
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Microcirculation; Biomarkers; Myocardial Ischemia
Endothelial and Microvascular Functions in Patients With Myocardial Ischemia
Cardiovascular diseases (CVD) are responsible, throughout the world, for high mortality rates and cardiovascular morbidity. Endothelial dysfunction is the earliest marker of clinical atherosclerosis development.
- Trial name
- NCT03243968
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Atrial Fibrillation
Imaging-based, Non-invasive Diagnosis of Persistent Atrial Fibrillation
The main objective of the present project is to develop an imaging-based tool to determine the origin and cause of persistent atrial fibrillation (AF).
- Trial name
- imATFIB (NCT03584126)
- Testing
- Electrocardiography, ecocardiography and MRI.
- Where
- Romania
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- County Clinical Emergency Hospital Cluj-Napoca
Coronary Artery Disease, Artificial Heart Device User
Deep Learning Algorithm for Detecting Obstructive Coronary Artery Disease Using Fundus Photographs
Artificial Intelligence, trained through model learning, can quickly perform medical image recognition and is widely used in early disease screening and assisted diagnosis.
- Trial name
- NCT06102226
- Testing
- coronary artery imaging (coronary CTA or coronary angiography)
- Where
- China
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Yong Zeng
Atrial Fibrillation
The Effectiveness of Patch-Based Screening for Pre-Symptomatic Atrial Fibrillation to Improve Patient Outcome
The goal of the screening trial is to determine whether early screening for atrial fibrillation improves outcomes, including lowering the chance of death, hospitalization for stroke, blood clots, heart failure, heart attack, and…
- Trial name
- VALIANT-AF-S (NCT06953778)
- Testing
- Zio XT® Patch
- Where
- United States
- Volunteers
- 24,060 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Turner Syndrome
Risk of Diabetes in Young Turner Syndrome Patients
Turner Syndrome is a common genetic disorder. Seventy percent of adults with Turner Syndrome have abnormalities in glucose metabolism which can lead to diabetes.
- Trial name
- NCT02160717
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Healthy Volunteers
Study to Assess the Effect of AZD4831 on the Pharmacokinetics (Drug Behavior in the Body) of Midazolam
The study is an open-label, fixed-sequence, cross-over study conducted at a single Clinical Unit to assess the pharmacokinetics (PK) of midazolam in healthy male and female (non-childbearing potential) subjects when administered…
- Trial name
- NCT05052710
- Testing
- AZD4831, Midazolam
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Abdominal Obesity, Metabolic Syndrome
WAVE Study- Walking and Aging in VErona Study
Monocentric unblinded two parallel-group randomized controlled trial to evaluate the effect of diet with or without Nordic Walking on weight loss, physical performance and cardiovascular risk factors in overweight and obese…
- Conditions
- Abdominal Obesity, Metabolic Syndrome, Disability Physical, Sarcopenic Obesity
- Trial name
- WAVE (NCT03212391)
- Testing
- Diet, Walking, Nordic Walking
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Long QT Syndrome
Metabolism of Patients With Genetically Caused Cardiac Arrhythmia
Loss-of-function mutations in voltage-gated potassium channels cause long QT syndrome (LQTS) due to a prolonged cardiac repolarisation phase.
- Trial name
- NCT02775513
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cardiovascular Diseases
Reference Intervals for Sonoclot Analysis in Chinese
The reference intervals for Sonoclot Analysis may be different between Chinese and American. So far, no reference interval has been established in Chinese for Sonoclot Analysis.
- Trial name
- NCT01759433
- Where
- China
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Wuhan Asia Heart Hospital
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