Clinical trials: Cardiovascular Disease, Obesity
Diabete Mellitus, Hypertension
Faisalabad Initiative of Research and Management of NCDs
The burden of noncommunicable diseases (NCDs) continues to rise globally, and they have become the leading cause of morbidity and mortality, accounting for over 70% of deaths worldwide¹.
- Conditions
- Diabete Mellitus, Hypertension, Hypercholerolemia, Obesity (Disorder)
- Trial name
- FIRM-NCD (NCT07676214)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Getz Pharma
Cardiovascular Disorder, Coronary Artery Disease
A Sugar-Sweetened Beverage Reduction Intervention for Native American Men
This clinical trial develops and tests a culturally-appropriate educational program (Indigenous SIPin) for reducing sugar-sweetened beverage consumption in men affiliated with Native American athletics communities.
- Conditions
- Cardiovascular Disorder, Coronary Artery Disease, Diabetes Mellitus, Obesity-Related Malignant Neoplasm
- Trial name
- NCT06029517
- Testing
- Education Intervention, Observation of Indigenous SIPin Interventon, Discussion
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Overweight, Obesity
Weight Loss in Chronic Disease Patient Population
This study will assess the effect of in-home tele-health monitoring on health outcomes for LSUHCSD chronic disease, overweight or obese patients diagnosed with type II diabetes or hypertension.
- Conditions
- Overweight, Obesity, Diabetes, Hypertension
- Trial name
- NCT01155050
- Testing
- Tele-health Home Monitoring, TrestleTree Telephone Coaching, Tele-health Home Monitoring Plus Trestle Telephone Coaching
- Where
- 3 sites in United States
- Volunteers
- 202 people
- Sponsor
- Pennington Biomedical Research Center
Obesity
Macronutrient Relations and Weight Loss in Obese Subjects
The burden of overweight and obesity has dramatically increased during the last decades. High carbohydrate intake, particularly refined carbohydrates, probably increase the risk of obesity, type 2 diabetes, and metabolic…
- Trial name
- NCT00868387
- Testing
- energy-restricted, CHO-restricted diet, energy-restricted, CHO-rich diet
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Atrial Fibrillation, Obesity
DUTCH Weight Control in Atrial Fibrillation Study
Quantify the effect of an innovative weight loss management on rhythm control.
- Conditions
- Atrial Fibrillation, Obesity, Weight Loss
- Trial name
- DUTCH-WAIST (NCT06184633)
- Testing
- Semaglutide 3.2 MG/ML
- Where
- 20 sites in Netherlands
- Volunteers
- 280 people
- Sponsor
- Rijnstate Hospital
Obesity
Family Intervention for Obese Children Using Portion Control Strategy for Weight Control
Obesity in children is a serious disease that is associated with increased mortality and decreased life expectancy. A simple tool used to assist in controlling portions (and therefore calorie intake) at mealtime would be of…
- Trial name
- FOCUS (NCT00881478)
- Testing
- Nutrition counseling + portion control tool, Nutrition counseling
- Where
- Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Overweight and Obesity, Cardiovascular Risk Factors
Web-based Personal or Peer Group Weight Management Study
The PERGROUP trial aims to investigate whether Web-based personal or Web-based group counselling weight management program can help to achieve lifestyle changes needed for weight loss and improvement in quality of life and…
- Conditions
- Overweight and Obesity, Cardiovascular Risk Factors, Quality of Life, Work Ability
- Trial name
- PERGROUP (NCT03904160)
- Testing
- Weight management
- Where
- Finland
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Turku
Insulin Resistance, Type 2 Diabetes
Fish Gelatin Supplement and Omega-3 Supplement in Obese or Overweight Subjects With Insulin Resistance
The present study was conducted to test whether a fish gelatin supplement combined with an omega-3 polyunsaturated fatty acid supplement can exert beneficial and sex-specific effects on insulin sensitivity, glucose tolerance…
- Trial name
- NCT01215903
- Testing
- Fish gelatin and omega-3 polyunsaturated fatty acid, Omega-3 polyunsaturated fatty acid
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Laval University
Chronic Kidney Disease in Type 2 Diabetes, Obesity & Overweight
Visceral Adipose Tissue and Liver Changes Associated With Semaglutide in CKD
Obesity is considered a global pandemic and is associated with various diseases and metabolic complications, such as type 2 diabetes mellitus, high blood pressure, cholesterol disorders, cancer, cardiovascular disease, and kidney…
- Trial name
- ADIPOLIVE (NCT07187830)
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- University of Alberta
Cardiovascular Syndrome, Metabolic
High-Intensity Interval Training(HIIT) on Cardio-metabolic Risk in School-age Children
This study aims to evaluate the health promotion effects of high-intensity interval training (HIIT) intervention on school-age children who are at high risk for cardiovascular disease (CVD), as well as the long-term adherence and…
- Trial name
- NCT06416488
- Testing
- HIIT intervention, General health education
- Where
- China
- Volunteers
- 336 people
- Sponsor
- Children's Hospital of Fudan University
Atherosclerotic Cardiovascular Disease (ASCVD), Chronic Kidney Disease (CKD)
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)
The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent the worsening of kidney function.
- Trial name
- NCT06383390
- Testing
- Retatrutide
- Where
- 742 sites in United States, Argentina and 25 more
- Volunteers
- 10,000 people
- Sponsor
- Eli Lilly and Company
Ischemic Heart Disease, Obesity
Expressive Writing for Heart Healing
This study will determine whether the psychological and physical benefits of expressive writing extend to obese in-patients with Ischemic Heart Disease (IHD)referred to cardiac rehabilitation
- Trial name
- WrittenHeart (NCT01253486)
- Testing
- Disease-related Expressive writing, Active Comparator: Traditional expressive writing
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Auxologico Italiano
Obesity, Obesity, Abdominal
Effect of Balanced Hypocaloric Diet Associated With Supplementation of Eggplant Meal in the Remission of Cardiovascular Risk Factors
Cardiovascular diseases (CVD) prevail as the main cause of death in developed and developing countries and are among the most frequent causes of disabilities in Brazil and in the world.
- Trial name
- NCT01622309
- Testing
- eggplant meal, cassava meal
- Where
- Brazil
- Volunteers
- 363 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Obesity, Hypertension
The Short-Term Effect of a Technology Driven Weight Control (SMART) Program for Obese Adults
The purpose of this study is to evaluate the short-term effect of a technology based weight reduction program for obese (BMI > 30 kg/m2) adults in a primary care office.
- Trial name
- WCPC (NCT00624598)
- Testing
- SMART
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Colorado Center for Chronic Care Innovations, Inc.
Cardiovascular Diseases, Hyperlipidemia
Home-based Exercise for Management of HIV-associated Cardiovascular Disease Risk
Because of advances in drug treatment, people living with HIV/AIDS (PLWHA) are living longer, but are also at greater risk for cardiovascular disease (CVD) and diabetes.
- Conditions
- Cardiovascular Diseases, Hyperlipidemia, Obesity
- Trial name
- NCT01377064
- Testing
- Physical Activity Group, Standard Care Group
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of South Carolina
Venous Thrombosis, Pulmonary Embolism
Investigation Into the Therapeutic Dosage of Fondaparinux Sodium, a Medication Used to Prevent Blood Clots in Morbidly Obese Volunteers
Morbidly obese individuals are at high risk for potentially life threatening blood clots around the time of abdominal surgical procedures.
- Trial name
- NCT00436787
- Testing
- Fondaparinux Sodium
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- University of Pittsburgh
Obesity, Adolescent Obesity
Exposure to CARDIovascular Risk Assessed by Cardiac Adiposity in oBese adOlescents Eligible to a Residential Long-term Lifestyle Intervention by Diet and eXercise (CARDIBOX)
The high prevalence of childhood obesity is a major public health issue, worldwide. Childhood obesity is associated with a high risk of cardiovascular events in adulthood, but recent studies also point out the development of…
- Trial name
- CARDIBOX (NCT04310371)
- Testing
- 3-month lifestyle intervention
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Overweight and Obesity
Differences in Sitting Versus Standing on Metabolic and Cardiovascular Measurements
This investigations examined the effect that posture has on metabolic and cardiovascular measurements. Further, it will explore the potential for body weight status or physical activity to influence these relationships.
- Trial name
- NCT03927638
- Testing
- sit/stand
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Montclair State University
Heart Diseases
Identifying Genes That May Increase the Risk for Heart Disease in African Americans
Heart disease and stroke disproportionately affect African Americans in the United States. These conditions are likely caused by both environmental and genetic factors.
- Trial name
- NCT00344136
- Where
- United States
- Volunteers
- 5,302 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Health, Obesity
The SI! Program Reintervention for Elementary Schools Trial
Background and objectives: The SI! Program is a multilevel school-based intervention that has been previously evaluated in different ages in three countries.
- Trial name
- PSIR (NCT06715358)
- Testing
- Reintervention, Late intervention
- Where
- Spain
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Foundation for Science, Health and Education, Spain