Clinical trials: Cardiovascular Disease (CVD)
Cancer, Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma)
Survivors Uniting for Remote Guided Exercise
The goal of this research study is to look at how live, online group exercise compares to recorded videos for helping increase physical activity levels, improve physical fitness and quality of life, and reduce loneliness among…
- Conditions
- Cancer, Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Physical Activity, Physical Activity Behavior
- Trial name
- SURGE (NCT07290309)
- Testing
- Virtually Supervised Exercise Sessions, Asynchronous Group
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Colorado State University
Myocardial Infarction
AMI-DC in Patients With Anterior Wall Myocardial Infarction
The purpose of this trial is to assess the safety of AMI-DC treatment. The participants who voluntarily sign the consent form will be screened according to the inclusion/exclusion criteria then allocated either to the…
- Trial name
- AMI-DC (NCT05554484)
- Testing
- Autologous peripheral blood-derived tolerogenic dendritic cells
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- The Catholic University of Korea
Cardiac Arrest, Cardiopulmonary Arrest
Lowlands Saves Lives: A Randomized Trial Comparing CPR-quality Between Face-to-face vs. Lifesaver VR Training
The objective of the Lowlands Saves Lives trial is to compare the quality of cardiopulmonary resuscitation (CPR) between face-to-face versus Lifesaver Virtual Reality smartphone application trained participants using a randomized…
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest, Out-Of-Hospital Cardiac Arrest
- Trial name
- NCT04013633
- Testing
- Lifesaver virtual reality training, Face-to-face training
- Where
- Netherlands
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Stroke
A Mobile Brain/Body Imaging Platform for the Assessment and Optimization of Post-stroke Overground Robotic Gait Treatments
The study aims to identify neural biomarkers that can be used to monitor the recovery of locomotion and movement of post-stroke patients, both in natural settings and with enriched treatment using robotic device.
- Trial name
- COBI (NCT07510633)
- Testing
- overground wearable robotic device
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Franco Molteni
Mitral Regurgitation
Repair of Ischemic Mitral Regurgitation: Comparison Between Flexible and Rigid Annuloplasty Rings
Mitral valve repair for ischemic mitral regurgitation is performed primarily by annuloplasty. There is some degree of late failure, which may be due in part to the type of ring employed.
- Trial name
- IMR2 (NCT00491452)
- Where
- Israel
- Sponsor
- Shaare Zedek Medical Center
Pericardial Effusion
Non Steroidal Anti Inflammatory Treatment for Post Operative Pericardial Effusion
The aim of the sudy is to evaluate, through clinical, biological and transthoracic echocardiography follow up, the evolution of post operative (cardiac surgery) pericardial effusion and mostly to evaluate the efficiency of a non…
- Trial name
- NCT00247052
- Testing
- diclofenac
- Where
- 5 sites in France
- Volunteers
- 200 people
- Sponsor
- French Cardiology Society
Hemorrhoids, Open Hemorrhoidectomy
Hemorrhoids: Options of Traditional Hemorrhoidectomy
The goal of this prospective clinical trial is to compare the outcomes of several technical options of open hemorrhoidectomy in patients with symptomatic hemorrhoids.
- Trial name
- NCT06132152
- Testing
- Open hemorrhoidectomy with 'cold' scalpel, Open hemorrhoidectomy with electrosurgical scalpel
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- Center of Endourology "Endocenter"
Relapsed/Refractory Multiple Myeloma
A Study of Subcutaneous (SC) AMG 701 in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
A study to evaluate the safety and tolerability of subcutaneous (SC) AMG 701 in participants with relapsed or refractory multiple myeloma (RRMM) to determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D)
- Trial name
- ProxiMMity-1 (NCT04998747)
- Testing
- AMG 701
- Sponsor
- Amgen
Alzheimer Disease, Dementia
SAFE at Home: A Service to Provide Social Engagement to Community-Dwelling Persons With Dementia
The proposed Phase 1 study will involve initial development and evaluation of a new service called Social Activities For Engagement at Home or SAFE at Home (SaH).
- Conditions
- Alzheimer Disease, Dementia, Dementia, Vascular, Dementia, Mixed
- Trial name
- NCT05516147
- Testing
- SAFE at Home
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Hopeful Aging
Heart Disease, Coagulopathy
Comparison of Three Management Strategies for Post Cardiac Surgery Bleeding
Open-heart surgery frequently results in abnormal clotting, which in turn results in excessive blood loss and the need for transfusion of multiple blood products to patients and leads to adverse outcomes.
- Trial name
- NCT00188747
- Testing
- Thromboelastograph, Point of Care
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University Health Network, Toronto
Congenital Heart Disease
Impact of a Cardiac and Mental Health Rehab Program on Well-Being and Fitness in Young Adults With Fontan Circulation: A Randomized Trial
Helping Young Adults With Fontan Circulation Feel Better and Stay Active What is the study about? This study looked at how a special program could help young adults with Fontan circulation feel better mentally and physically.
- Trial name
- (NCTXXXXXXXX) (NCT06844149)
- Testing
- CPR; (Cardiac and Psychosocial Rehabilitation) with Cardiac Rehabilitation, CR; Home-Based Cardiac Rehabilitation, Usual Care
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Samsung Medical Center
Diabetic Retinopathy, Depression
Diabetic Retinopathy as a Marker of Cognitive Dysfunction and Depression
In recent years damage to the nerve fibers in the retina has been experienced as an early sign of complications resulting from type 2 diabetes.
- Conditions
- Diabetic Retinopathy, Depression, Cognitive Impairment, Cognitive Dysfunction
- Trial name
- DIRMA (NCT04610749)
- Where
- Denmark
- Volunteers
- 148 people
- Sponsor
- Region of Southern Denmark
Obesity
Supplemental Calcium in Overweight People
This study will examine the health effects of calcium supplements in overweight adults. Overweight adults often eat a diet low in calcium.
- Trial name
- NCT00030238
- Testing
- Calcium supplement
- Where
- United States
- Volunteers
- 540 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cardiometabolic Disease
Metagenomics and Integrative Systems Medicine of Cardiometabolic Diseases
Supported by state-of-the-art systems medicine competences including integrative computational and functional genomics, the overarching goal of the trial is to investigate the impact of qualitative and quantitative changes in the…
- Trial name
- METACARDIS (NCT02059538)
- Testing
- Adipose tissue biopsies (omental and subcutaneous) liver, CT-scan, Stools sampling
- Where
- 3 sites in Denmark, France and 1 more
- Volunteers
- 2,350 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocardial Infarction
Remote Exercise SWEDEHEART Study
The overall aim of the study is to evaluate if remote video exercise-based cardiac rehabilitation (exCR), offered as an alternative to centre-based exCR, can increase participation in exCR sessions post myocardial infarction (MI).
- Trial name
- NCT04260958
- Testing
- Exercise-based cardiac rehabilitation
- Where
- 25 sites in Sweden
- Volunteers
- 1,500 people
- Sponsor
- Sahlgrenska University Hospital
Coronary Artery Disease
Pycnogenol and Endothelial Function in Coronary Artery Disease
Pycnogenol® is a proprietary bark extract of the French maritime pine tree (Pinus pinaster ssp. atlantica). Pycnogenol® has prevented pathologic symptoms such as chronic inflammation and increased platelet aggregation, a risk…
- Trial name
- NCT00641758
- Testing
- Pycnogenol
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- University of Zurich
Stroke, Acute
Hemodynamic Response and Motor Functions Following Transcranial Direct Current Stimulation in Acute Stroke
The aim of the present study is to evaluate the possible effect of using dual-tDCS applied before conventional physical therapy on motor functions and hemodynamic response
- Trial name
- NCT04051658
- Testing
- Transcranial direct current stimulation
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Mahidol University
Moyamoya Disease
Efficacy and Safety of rTMS for Cognitive Rehabilitation in Moyamoya Disease
The purpose of this study is to evaluate the safety and effectiveness of transcranial magnetic stimulation (TMS) therapy in moyamoya patients who received surgical revascularization.
- Trial name
- NCT03543748
- Testing
- Transcranial Magnetic Stimulation
- Volunteers
- 50 people
- Sponsor
- Huashan Hospital
Coronary Artery Disease
Medtronic RevElution Trial
The purpose of this trial is to evaluate the clinical safety and efficacy of the Polymer-Free Drug-Eluting coronary stent system for the treatment of de novo lesions in native coronary arteries with a reference vessel diameter…
- Trial name
- RevElution (NCT02480348)
- Testing
- Polymer-free DES (Drug Eluting Stent)
- Where
- 15 sites in Australia, Brazil and 1 more
- Volunteers
- 109 people
- Sponsor
- Medtronic Vascular
Renal Artery Stenosis, Aortic Dissection
On-table Renal Perfusion Evaluation Renal Artery Stenosis or Obstruction
1. Evaluate the feasibility for the on-table evaluation of the renal perfusion by using Syngo Dyna Parenchymal Blood Volume(PBV) Body; 2.
- Conditions
- Renal Artery Stenosis, Aortic Dissection, Renal Perfusion, Renal Artery Obstruction
- Trial name
- NCT03530748
- Testing
- Endovascular therapy and Imaging Acquisition
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Zhongshan Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.