Clinical trials: Cardiovascular Disease (CVD)
Cardiovascular Diseases
Wearable Devices to Promote Physical Activity
This study evaluates the effect of a new wearable device, that measures physical activity level based on heart rates, on relevant health outcomes including cardiorespiratory fitness.
- Trial name
- HUNT4-PAI (NCT03270202)
- Testing
- PAI group, Usual care
- Where
- Norway
- Volunteers
- 175 people
- Sponsor
- Norwegian University of Science and Technology
Arrhythmia, Bradycardia
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
The main purpose of the Product Performance Report (formerly referred to as System Longevity Study) is to evaluate long-term performance of Medtronic market-released cardiac rhythm products by analyzing product survival…
- Conditions
- Arrhythmia, Bradycardia, Heart Failure, Sinus Tachycardia
- Trial name
- PPR (NCT00271180)
- Testing
- Device
- Where
- 333 sites in United States, Australia and 33 more
- Volunteers
- 20,000 people
- Sponsor
- Medtronic
Congenital Heart Defects, VSD
Bioabsorbable Occluder for Outlet VSD: Safety and Aortic Valve Effects
This study aims to evaluate the efficacy and safety of transcatheter bioabsorbable occluder closure in patients with outlet-type ventricular septal defect (outlet VSD), with a focus on assessing its impact on aortic valve…
- Trial name
- ABSORB-VSD (NCT07040579)
- Testing
- transcatheter closure of outlet VSDs with bioabsorbable occluders
- Where
- China
- Volunteers
- 50 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
Atherosclerosis of Artery
Screening for Atherotic Plaques by Ultrasound for Assessing Cardiovascular Risk
Cardiovascular disease is a common diagnosed and treated condition in private practices of primary health care. There is growing evidence that atherosclerotic plaques as predictors for stroke and heart attack are more prevalent…
- Trial name
- NCT03499496
- Testing
- ultrasound guided detection of atherosclerotic plaques
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cabinet de Medecine Interne Générale Demetrio Pitarch
Muscle Spasticity, Cerebrovascular Accident
Asian Botulinum Clinical Trial Designed for Early Stroke Spasticity
The aim of this clinical study is to investigate the efficacy and safety of Dysport® in patients with early onset of upper limb spasticity within 2-12 weeks after stroke.
- Trial name
- NCT00234546
- Testing
- Botulinum toxin type A
- Where
- 5 sites in Hong Kong, Malaysia and 3 more
- Volunteers
- 162 people
- Sponsor
- Ipsen
Critical Limb Ischemia
BEST vCLI Registry
For subjects with critical limb ischemia, identify patient, physician/hospital, and geographic factors associated with variations in treatment strategies; compare treatments and outcomes, including quality of life, cost and cost…
- Trial name
- BEST (NCT04191746)
- Where
- United States
- Volunteers
- 1,009 people
- Sponsor
- Duke University
Peripheral Artery Disease
ILLUMENATE Pivotal Post-Approval Study (PAS)
The ILLUMENATE Pivotal PAS is a continued follow-up study which will include 300 subjects from forty-three (43) sites across the United States and Austria previously enrolled in the ILLUMENATE Pivotal pre-market study to evaluate…
- Trial name
- NCT03421561
- Testing
- Stellarex 0.035" OTW Drug-coated Angioplasty Balloon, EverCross™ 0.035 PTA Balloon Catheter
- Where
- 41 sites in United States, Austria
- Volunteers
- 300 people
- Sponsor
- Spectranetics Corporation
Diabetes Mellitus, Cardiovascular Diseases
Estudo Longitudinal de Saúde do Adulto (Brazilian Longitudinal Study of Adult Health )
The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) aims to contribute with relevant information regarding the development and progression of clinical and subclinical chronic diseases, particularly cardiovascular…
- Trial name
- ELSA-Brasil (NCT02320461)
- Volunteers
- 15,105 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Mild Dementia, Mild Cognitive Impairment
The Swedish BioFINDER - Primary Care Study
The overall aim of the study is to improve the diagnostic accuracy of AD and cognitive impairment in primary care settings to ensure better care and treatment as well as facilitate correct referrals to specialized memory clinics.
- Conditions
- Mild Dementia, Mild Cognitive Impairment, SCD, Alzheimer Disease
- Trial name
- ADetect (NCT06120361)
- Testing
- Plasma APS 2 score, Plasma p-tau217/np-tau217, Plasma p-tau217
- Where
- Sweden
- Volunteers
- 1,200 people
- Sponsor
- Skane University Hospital
Stroke
Investigation of the Effect of Orthosis Use for Control of Knee Hyperextension in Chronic Stroke Patients
The aim of this study is to examine the effect of using foot-ankle orthosis at different angles on hyperextension control in stroke patients.
- Trial name
- NCT05609461
- Where
- Turkey (Türkiye)
- Sponsor
- Hacettepe University
Atherosclerosis
Examining the Genetic Predictors of Coronary Artery Calcification in African Americans
Coronary artery disease (CAD) is an important health concern for African Americans, who are diagnosed with CAD at high rates. Coronary artery calcification, which is characterized by calcium deposits in the coronary arteries, is…
- Trial name
- NCT00925561
- Where
- United States
- Volunteers
- 752 people
- Sponsor
- University of Michigan
Atrial Fibrillation and Other Dysrhythmias | Patient
French Database of Left Atrial Appendage Closure
Patients with atrial fibrillation are exposed to a high risk of thrombus in the left atrium that can induce cerebral vascular events or systemic embolisms.
- Trial name
- FLAAC (NCT02252861)
- Testing
- Percutaneous Left Atrial Appendage Closure in routine care
- Where
- France
- Volunteers
- 840 people
- Sponsor
- Henri Mondor University Hospital
Amyloidosis
Impact of a Cardiac Rehabilitation Program on Patients With Cardiac Amyloidosis
The goal of this clinical trial is to learn if a structured cardiac rehabilitation program can help people with cardiac amyloidosis improve their ability to exercise and their quality of life.
- Trial name
- RECARDA (NCT07494942)
- Testing
- Cardiac Rehabilitation Program
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Montpellier
Ischemic Stroke
Intracerebral Hemorrhage Due to Oral Anticoagulants: Prediction of the Risk by Magnetic Resonance
The purpose of this study is to determine whether Magnetic Resonance Imaging may predict the risk of Intracerebral Hemorrhage for patients with ischemic stroke who receive indefinite oral anticoagulation
- Trial name
- HERO (NCT02238470)
- Testing
- oral anticoagulants
- Where
- 30 sites in Italy, Spain
- Volunteers
- 1,000 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Arrhythmias, Cardiac, Atrial Fibrillation
Physician Acceptance of the NeuTrace System for Cardiac Electroanatomic Mapping
The trial is a prospective, non-randomized, single-arm feasibility trial to evaluate physician acceptance of the NeuTrace System v1.0 for cardiac electroanatomic mapping.
- Conditions
- Arrhythmias, Cardiac, Atrial Fibrillation, Atrial Flutter
- Trial name
- NCT05214170
- Testing
- Electroanatomic mapping with the NeuTrace System
- Where
- Lithuania
- Volunteers
- 20 people
- Sponsor
- NeuTrace, Inc.
Congenital Heart Disease, Unfractionated Heparin
Comparison of the Best Method for Measuring Anti-Xa Activity in Children Receiving Unfractionated Heparin in Cardiac Intensive Care (COMPAXE-HNF)
This study aims to compare the accuracy of two different blood sampling methods from a central venous catheter (CVC) for measuring anti-Xa activity in children receiving unfractionated heparin (UFH) from this CVC.
- Conditions
- Congenital Heart Disease, Unfractionated Heparin, Anti Xa Activity
- Trial name
- COMPAXE-HNF (NCT07365670)
- Testing
- blood sampling for measuring anti-Xa activity, measurement of anti-XA activity
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Metabolic Syndrome
P20 Extending Sleep to Reverse Metabolic Syndrome
This pilot study will test the acceptability and feasibility of a sleep extension intervention in community-dwelling, short-sleeping, racially/ethnically diverse middle-aged adults with MetS.
- Trial name
- NCT03596983
- Testing
- Sleep Intervention, Week 2 Intervention
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- NYU Langone Health
Diabetes, Cardiovascular Disease
Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora Populations
Background: African Americans have one of the highest rates of type 2 diabetes in the United States, and often have other medical problems related to obesity and cardiovascular disease.
- Trial name
- NCT01316783
- Where
- United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Heart Failure
Assessment of adherenCe tO Medical theraРy and Its infLuence on Long-term Outcomes In pAtieNts With Heart Failure
The aim of this prospective cohort study is to assess the adherenсe to medical therapy and its influence on long-term outcomes in patients with chronic heart failure in the outpatient registry
- Trial name
- COMPLIANCE (NCT04262583)
- Where
- Russia
- Volunteers
- 72 people
- Sponsor
- National Research Center for Preventive Medicine
Chest Pain, Stenosis
Diagnosis of Myocardial Ischemia With MCG Using SPECT as a Reference Standard
This is a prospective clinical study aiming to investigate the efficacy of Magnetocardiography (MCG) in detecting myocardial ischemia in patients of a suspected non-ST-elevation-acute coronary syndrome (NSTE-ACS) by using Single…
- Conditions
- Chest Pain, Stenosis, Myocardial Ischemia
- Trial name
- NCT06255769
- Testing
- Magnetocardiography, Single photon emission computed tomography (SPECT)
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Qilu Hospital of Shandong University
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