Clinical trials: Cardiovascular Disease Risk Factors
Depression, Hypertension
Biological CVD Risk Factors in Older Depressed Patients
The purpose of this study is to determine if improvements in mood will ameliorate autonomic dysregulation, HPA dysfunction and typical (e.g.
- Conditions
- Depression, Hypertension, Hypercholesterolemia
- Trial name
- NCT00318864
- Testing
- Cognitive behavioral therapy
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity, Overweight
Method-of-Use Study Assessing the Effect of Naltrexone Sustained Release (SR)/ Bupropion SR on Body Weight and Cardiovascular Risk Factors in Overweight and Obese Subjects
The purpose of this Phase 3b study is to assess the effects of combination therapy with naltrexone SR/bupropion SR (NB) used in conjunction with a comprehensive lifestyle intervention (CLI) and in a manner consistent with its…
- Trial name
- NCT01764386
- Testing
- NB, CLI, Usual Care
- Where
- 15 sites in United States
- Volunteers
- 242 people
- Sponsor
- Orexigen Therapeutics, Inc
Venous Thromboembolism, Venous Thromboses
Risk Stratification for Venous Thromboembolism in Hospitalized Medical Patients
Hospital-acquired venous thromboembolism (HA-VTE) is one of the leading preventable causes of in-hospital mortality, but prevention of VTE in hospitalized medical patients remains challenging, as preventive measures such as…
- Conditions
- Venous Thromboembolism, Venous Thromboses, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- RISE (NCT04439383)
- Where
- 3 sites in Switzerland
- Volunteers
- 1,353 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cardiovascular Diseases, Quality of Life
Effects of Physical Activity on Cardiovascular Risk and Quality of Life
Community intervention trial, randomized, to promote regular PA and social and cultural support activities for 9 months in older-adult primary care users and assess their effects on cardiovascular risk factors and health-related…
- Trial name
- NCT02767739
- Testing
- Physical, social and cultural activities
- Volunteers
- 419 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Metabolic Diseases, Type 2 Diabetes, Cardiovascular Disease
Effect of Carnosine on Diabetes and Cardiovascular Risk Factors
Carnosine is a naturally occurring compound with a potential health benefits. In animal studies, carnosine supplementation reduces manifestation of chronic civilization diseases, regulates subclinical inflammation, protein…
- Trial name
- Carnorisk (NCT02011100)
- Testing
- Carnosine
- Where
- 2 sites in Slovakia
- Volunteers
- 28 people
- Sponsor
- Jozef Ukropec
Growth Hormone Deficiency, Cardiovascular Diseases
GH and Cardiovascular Risk Factors
Rationale: Abnormally low and high levels of insulin-like growth factor-I (IGF-I) are both associated with increased metabolic risk.
- Conditions
- Growth Hormone Deficiency, Cardiovascular Diseases, Metabolic Syndrome, Cognition
- Trial name
- NCT01877512
- Testing
- Change in daily dosage of Growth Hormone
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Amsterdam UMC, location VUmc
Typical Atrial Flutter, Risk Factors With Future Development of Atrial Flutter
Pulmonary Vein Isolation To Reduce Future Risk Of Atrial Fibrillation In Patients Undergoing Typical Flutter
The purpose is to compare long term occurrence of atrial arrhythmias including atrial fibrillation (AF) and thromboembolic complications including cerebrovascular events (CVE) in patients with typical atrial flutter (AFLT)…
- Trial name
- REDUCE AF (NCT01710150)
- Testing
- CTI ablation alone, CTI ablation and Pulmonary vein isolation (PVI)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Dyslipidemia, Inflammation
Cardioprotective Effects of Green Tea Versus Maté Intake
The investigators aim to study the effects of green tea and maté consumption on lipid and inflammatory profiles in dyslipidemic and overweight subjects.
- Conditions
- Dyslipidemia, Inflammation, Obesity
- Trial name
- NCT00933647
- Testing
- Yerba Mate Tea, Green tea, Apple tea
- Where
- Brazil
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Cardiovascular Diseases
Modulation of Cardiovascular Risk Factors by the Diet
The interventional study will evaluate effectiveness and potential of a 'cardioprotective diet' for adults with increased risk for cardiovascular diseases (CVD).
- Trial name
- MoKaRi-Diet (NCT02637778)
- Testing
- Cardioprotective diet, Cardioprotective diet + 3 g EPA + DHA/d
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Jena
Cystic Fibrosis, Endothelial Dysfunction
Vascular Health and Function in Cystic Fibrosis
The goal of this observational study is to learn whether blood vessel health and function differ between adults aged 40 years or older with cystic fibrosis (CF) who are taking CFTR modulator therapy and healthy adults of the same…
- Conditions
- Cystic Fibrosis, Endothelial Dysfunction, Cardiovascular Risk Factor
- Trial name
- CF-VHF (NCT07904325)
- Testing
- Non-invasive vascular, cerebrovascular and autonomic assessment
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Abdominal Aortic Aneurysm (AAA)
Development of Novel Imaging Markers Predicting the Progression of Abdominal Aortic Aneurysm Using 3D Computed Tomography
Study purpose: This study will investigate anatomical factors associated with increased risk of major adverse aorta-related event and accelerated growth of abdominal aneurysm based on 3-dimensional analysis of CT images.
- Trial name
- NCT04333641
- Where
- South Korea
- Volunteers
- 323 people
- Sponsor
- Yonsei University
Atherosclerotic Cardiovascular Disease
Association Between Dietary Habits and Risk Factors for Atherosclerotic Cardiovascular Diseases in Assiut Governorate
Studying and investigating the association between dietary habits and risk factors for atherosclerotic cardiovascular diseases in Assiut governorate
- Trial name
- NCT03505073
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Assiut University
Metabolic Syndrome, Cardiovascular Disease
Identifying Biomarkers and Cardiovascular Risk Factors in Childhood Metabolic Syndrome
Metabolic syndrome (MetS) is highly prevalent all over the world. MetS is largely under-diagnosed in children and adolescents. Obesity and hypertension are two important requirements for criteria of MetS.
- Trial name
- NCT02518854
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
NAFLD, Liver Fibroses
Liver Damage and Cardiometabolic Disorders in NAFLD
Liver fibrosis is the most important prognostic factor in patients with non-alcoholic factor disease. Clinical and biological condition, as diabetes or mutation for PNPLA3, are well known factors associated with liver fibrosis…
- Conditions
- NAFLD, Liver Fibroses, Cardiovascular Diseases, Cardiovascular Risk Factor
- Trial name
- PLINIO (NCT04036357)
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- University of Roma La Sapienza
Type 2 Diabetes, Cardiovascular Risk Factor
Therapeutic Approach of Cardiovascular Risk Factors in T2DM by Gender
Background: Patients with type 2 diabetes mellitus (T2DM) are at 2- to 4-fold higher risk of cardiovascular mortality compared with non-diabetic subjects.
- Conditions
- Type 2 Diabetes, Cardiovascular Risk Factor, Gender
- Trial name
- NCT04653805
- Testing
- Current clinical practice in primary care of patients with type 2 diabetes mellitus
- Where
- Spain
- Volunteers
- 300,000 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Cardiovascular Diseases, Cardiovascular Risk Factor
Chinese Multi-provincial Cohort Study-Beijing Project
The Chinese Multi-provincial Cohort Study (CMCS)-Beijing project is a sub-study in CMCS participants from Beijing, which intended to investigate the progression and determinants of atherosclerosis and aging related health…
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Aging Problems, Smell Disorder
- Trial name
- CMCS-Beijing (NCT04253054)
- Testing
- Cardiovascular risk factors, Aging related health problems
- Where
- 3 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Risk Factor, Cardiovascular, Physical Activity
Exercise Effects on Appetite-regulating Hormones and Cardiovascular Risk Factors
The aim of this study is to examine the effect of a single bout of moderate exercise, standardized breakfast and buffet meal on appetite-related hormones, type two diabetes and cardiovascular risk factors with a comparison…
- Conditions
- Risk Factor, Cardiovascular, Physical Activity, Pre-diabetes
- Trial name
- NCT03698786
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kingston University
Death, Stroke
Postoperative Atrial Fibrillation and Long-term Survival
The aim of the investigators trial was to evaluate association between new onset postoperative atrial fibrillation (POAF) and late cardiovascular morbidity and mortality.
- Conditions
- Death, Stroke, Myocardial Infarction
- Trial name
- POAF (NCT02349269)
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Diabetes, Prediabetes
Meta-analyses of Pasta as Part of Low Glycemic Index Diets and Adiposity
Pasta is an important example of a food which can lower the glycemic index (GI) of the diet, a property that has been exploited extensively in studies of low GI dietary patterns.
- Conditions
- Diabetes, Prediabetes, Overweight, Obesity
- Trial name
- NCT02961088
- Testing
- Pasta as part of a low GI/GL diet
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Stroke, Cardiovascular Diseases
MIDNOR-STROKE- a Long Term Follow-up Study of Patients With First Ever Ischemic Stroke in Central Norway
Annually 13000 Norwegians experience an ischemic stroke. The number of stroke is anticipated to increase with 50% within 2030 due to a growing number of elderly.
- Conditions
- Stroke, Cardiovascular Diseases, Cardiovascular Risk Factor, Brain Ischemia
- Trial name
- NCT03962127
- Testing
- no intervention
- Where
- 8 sites in Norway
- Volunteers
- 800 people
- Sponsor
- Norwegian University of Science and Technology
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