Clinical trials: Cardiovascular Disease Risk Factors
Cardiovascular Diseases
HOPE-CVD-Virtual: A Virtual Trial to Evaluate the Primary Prevention of CVD
This 4-arm (1:1:1:1) single-blind randomized controlled trial. Arm 1 will communicate risk and encourage behavioral change that mirrors the standard pathway for health screening in Singapore.
- Trial name
- NCT05827861
- Testing
- HeartAge, HOPE-CVD Mobile App, Genetic Risk Score
- Where
- Singapore
- Volunteers
- 1,121 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Venous Thromboembolism
High-Risk Factors for VTE Death
Study population and characteristics This retrospective cohort study initially screened 105,168 consecutive hospitalized patients at Shihezi People's Hospital from February 2022 to June 2025.
- Trial name
- NCT07767279
- Testing
- comorbidity, Respiratory Failure, Sepsis
- Where
- China
- Volunteers
- 105,168 people
- Sponsor
- China International Neuroscience Institution
Atrial Fibrillation
Risk Factors of Stroke or Systemic Embolism After Atrial Fibrillation Ablation
To investigate the rate and risk factors of stroke or systemic embolism (SE) following atrial fibrillation (AF) ablation.
- Trial name
- NCT03479073
- Where
- 3 sites in South Korea
- Volunteers
- 3,198 people
- Sponsor
- Korea University Guro Hospital
Ischemic Stroke
China Angioplasty & Stenting for Symptomatic Intracranial Severe Stenosis
Patients with symptomatic stenosis of intradural arteries are at high risk for subsequent stroke. Since the SAMMPRIS trial, stenting is no longer recommended as primary treatment, however, the results of this trial, its inclusion…
- Trial name
- CASSISS (NCT01763320)
- Testing
- Intracranial stenting group, medical group
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Xuanwu Hospital, Beijing
Bipolar Disorder
BIMET Study: Evolution of Metabolic and Cardiovascular Risks Factors in Patients With Bipolar Disorder
To assess the prevalence of Metabolic Syndrome in Spanish population with Bipolar I or II Disorder. To analyse the clinical progress disease in patients with Bipolar I or II Disorder for 12 months using the assessment of the…
- Trial name
- BIMET (NCT00584961)
- Testing
- non-interventional
- Volunteers
- 553 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Obesity, Overweight
Method-of-Use Study Assessing the Effect of Naltrexone Sustained Release (SR)/ Bupropion SR on Body Weight and Cardiovascular Risk Factors in Overweight and Obese Subjects
The purpose of this Phase 3b study is to assess the effects of combination therapy with naltrexone SR/bupropion SR (NB) used in conjunction with a comprehensive lifestyle intervention (CLI) and in a manner consistent with its…
- Trial name
- NCT01764386
- Testing
- NB, CLI, Usual Care
- Where
- 15 sites in United States
- Volunteers
- 242 people
- Sponsor
- Orexigen Therapeutics, Inc
Infectious Disease, Cardiovascular Diseases
Metabolic and Infectious Diseases in La Réunion (the REUNION Population-based Study)
The aim of the present study is to determine the prevalence of cardiometabolic and infectious disease in La Reunion (french oversea department and region of France).
- Conditions
- Infectious Disease, Cardiovascular Diseases, General Population, Metabolic Disease
- Trial name
- NCT05400824
- Testing
- Blood, DNA, feces, urine, hair and skin microbiota collection
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Obesity, Abdominal, Hyperlipidemias
Obesity-related Health Benefits of Apples
Obesity is characterized by an underlying inflammatory state in which various inflammatory signaling molecules, termed cytokines, affect metabolic processes central to type 2 diabetes and cardiovascular disease; leading causes of…
- Conditions
- Obesity, Abdominal, Hyperlipidemias, Inflammation, Dysbiosis
- Trial name
- NCT03523403
- Testing
- Apples
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of Guelph
Atherosclerosis, Cardiovascular Diseases
Beijing Hospital Atherosclerosis Study
The Beijing Hospital Atherosclerosis Study (BHAS) is a prospective, single-center, observational cohort study performed at the Beijing Hospital in Beijing, China.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Coronary Artery Disease, Myocardial Ischemia
- Trial name
- BHAS (NCT03072797)
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Beijing Hospital
Cardiovascular Risk Factor
Primary Prevention of Cardiovascular Disease Among Female Hospital Employees: The Heart Smart for Women Intervention
This study aims to show that a 6-week program designed specifically for women can lead to sustainable behavior change and improvement in heart disease risk factors over one year among a cohort of 46 female employees recruited…
- Trial name
- Heart Smart (NCT04166097)
- Testing
- Heart Smart Interventional Program
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Northwell Health
Cardiovascular Diseases, Mental Disorder
Association Between Cardiovascular Diseases and Mental Illness
Cardiovascular diseases (CVD) are important public health concerns around the world and closely associated with the development and progression of mental illness, which in turn increases the risk of developing cardiovascular…
- Trial name
- NCT06239246
- Testing
- Behavioral
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ningbo No. 1 Hospital
Hypertension, Cardiovascular Risk Factor
Primary Care Usage of Health Promoting Messages
This project aims to investigate the use of e-health to assist health personnel in primary health care to carry out preventive measures of cardiovascular disease.The primary objective of the study is to examine the impact of…
- Trial name
- PUSHME (NCT04407962)
- Testing
- SMS group
- Where
- 9 sites in Sweden
- Volunteers
- 400 people
- Sponsor
- Lund University
Cardiovascular Diseases, Risk Factor, Cardiovascular
Prospective Urban Rural Epidemiology Study
To examine the impact of health determinants at the individual (e.g. health related behaviors) and societal level (e.g. environmental factors, health related policy, quality of health systems) on health outcomes (e.g.
- Conditions
- Cardiovascular Diseases, Risk Factor, Cardiovascular, Health Behavior, Environmental Exposure
- Trial name
- PURE (NCT03225586)
- Where
- 34 sites in Argentina, Bangladesh and 23 more
- Volunteers
- 200,000 people
- Sponsor
- Population Health Research Institute
Cardiovascular Risk Factor, Diabetes Mellitus, Type 2
Metabolic Syndrome in Diabetic Smokers Using Cigarettes & Combustion-Free Nicotine Delivery Systems
Very little is known about the impact of combustion-free nicotine delivery systems (C-F NDS) on cardiovascular risk factors in T2DM patients who smoke.
- Trial name
- DIASMOKE (NCT04231838)
- Testing
- TOBACCO CIGARETTES, COMBUSTION-FREE NICOTINE DELIVERY SYSTEMS (C-F NDS)
- Where
- United Kingdom
- Volunteers
- 576 people
- Sponsor
- Eclat Srl.
Overweight and Obesity, Cardiovascular Risk Factors
Web-based Personal or Peer Group Weight Management Study
The PERGROUP trial aims to investigate whether Web-based personal or Web-based group counselling weight management program can help to achieve lifestyle changes needed for weight loss and improvement in quality of life and…
- Conditions
- Overweight and Obesity, Cardiovascular Risk Factors, Quality of Life, Work Ability
- Trial name
- PERGROUP (NCT03904160)
- Testing
- Weight management
- Where
- Finland
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Turku
Cardiovascular Diseases, Coronary Disease
Effects of Training Intensity on the CHD Risk Factors in Postmenopausal Women
The purpose of this research is to find out whether training at different exercise intensities reduces the risk of developing cardiovascular disease (CVD) to a different extent.
- Trial name
- NCT00000108
- Testing
- Exercise
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Cardiovasculars Risk Factors, Heart Failure
Adapted Physical Activity and Prevention of Cardiovascular Risk in Elderly People Living With HIV:Comparative Study
A quasi-experimental and comparative study will be conducted in two different geographical areas (Europe-France and Africa-Cameroon) on a period of 18 months.
- Trial name
- NCT05201417
- Testing
- adapted physical activity
- Where
- 3 sites in Cameroon, France
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Support and Education Technic Centre
Advanced Gastric Cancer
Venous Thromboembolism in Advanced Gastric Cancer Patients
Venous thromboembolism (VTE), which includes pulmonary embolism (PE) and deep vein thrombosis (DVT), is a common complication and leading cause of death in cancer patients.
- Trial name
- NCT01047618
- Where
- South Korea
- Volunteers
- 259 people
- Sponsor
- Asan Medical Center
Venous Ulceration
A Study of Risk Factors for Venous Ulceration in Patients With Varicose Veins of Lower Extremities.
Varicose veins of lower extremities can lead to adverse consequences such as ulceration and hemorrhage, which seriously endangering the physical and mental health and quality of life for patients.
- Trial name
- NCT05519176
- Where
- China
- Volunteers
- 1,234 people
- Sponsor
- Yibing Wang
Coronary Disease, Coronary Syndrome
Prognostic Accuracy of the HEART Score in Undifferentiated Chest Pain: A Multicenter Validation Study
Chest pain remains one of the most common, potentially serious presenting complaints for adults emergency department visits with approximately 7.6 million yearly visits in the united states.
- Conditions
- Coronary Disease, Coronary Syndrome, Risk Factor, Cardiovascular, Major Adverse Cardiovascular Events
- Trial name
- NCT04580017
- Where
- 3 sites in Tunisia
- Volunteers
- 4,267 people, healthy volunteers welcome
- Sponsor
- University of Monastir
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