Clinical trials: Cardiovascular Disease Risk Factors
Psoriatic Arthritis
Tumor Necrosis Factors (TNF)-α Blockade for Psoriatic Arthritis
The purpose of this study is: To elucidate the immunomodulating properties of anti-TNF-α therapy in patients with psoriatic arthritis (PsA).
- Trial name
- NCT00432406
- Testing
- Infliximab, Etanercept
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Hypertension, Diabetes
Study of a Community Based Approach to Control Cardiovascular Risk Factors in India
The study is a 2 year community based cluster randomized controlled trial to assess the role that a community health worker led intervention, in concert with physician education, can play in controlling the principal…
- Conditions
- Hypertension, Diabetes, Smoking, Cardiovascular Diseases
- Trial name
- SEHAT (NCT02115711)
- Testing
- Community health worker
- Where
- India
- Volunteers
- 1,242 people
- Sponsor
- University Hospitals Cleveland Medical Center
Hypertension
Theobromine From Cocoa and Cardiovascular Risk Factors
The goal of this clinical trial is to examine whether consumption of dark chocolate affects blood pressure and a cardiovascular risk factor called trimethylamine N-oxide in Thai male participants with hypertension.
- Trial name
- NCT06820944
- Testing
- dark chocolate, white chocolate
- Where
- Thailand
- Volunteers
- 53 people
- Sponsor
- Chiang Mai University
Sudden Cardiac Death
Imaging Techniques for Identifying Factors of Sudden Cardiac Death Risk
Sudden cardiac death is a tragic event that strikes all age groups and is unfortunately increasing in prevalence. Because it is difficult to predict those at highest risk, this study is designed to test the hypothesis that new…
- Trial name
- NCT00181233
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Johns Hopkins University
Cardiovascular Risk Factor, Pre Diabetes
Effects of a Workplace Exercise Intervention on Cardio-Metabolic Health
Background: The rising levels of physical inactivity in the Eastern Mediterranean region (43.2%) and in the United Arab Emirates (38%) compared with the global levels of physical inactivity (31.2%) is alarming (6,15).
- Conditions
- Cardiovascular Risk Factor, Pre Diabetes, High Blood Pressure, Elevated LDL Cholesterol
- Trial name
- NCT04403789
- Testing
- Exercise Time, Supervised Group Exercise
- Where
- United Arab Emirates
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- United Arab Emirates University
Atherosclerosis, Cardiovascular Risk Factor
Early Vascular Ageing in the YOUth
This is a single-center observational study on adolescents to determine predictors of the early steps of the formation of atherosclerosis and to quantify their influence on Intima-Media-Thickness of the carotid artery and the…
- Conditions
- Atherosclerosis, Cardiovascular Risk Factor, Cardiovascular Diseases, Cardiovascular Pathology
- Trial name
- EVA4YOU (NCT04598685)
- Where
- Austria
- Volunteers
- 1,517 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Hypertension, Elevated Cholesterol
Effects of a 4-week Raw, Plant-based Diet on Anthropometric and Cardiovascular Risk Factors
This study evaluates the effects of a prescribed 4-week raw, plant-based dietary intervention in the treatment of excess body weight, hypercholesterolemia, and hypertension in the clinical setting.
- Conditions
- Hypertension, Elevated Cholesterol, Overweight and Obesity
- Trial name
- NCT03134235
- Testing
- Dietary Intervention
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Texas Woman's University
Metabolic Syndrome, Protection Against
Effects of Nature and Forest Therapy in Patients With Metabolic Syndrome and Cardiovascular Risk Factors
The aim of this study is to investigate the effects of regular forest therapy under guidance of a licensed nature therapist on patients with metabolic syndrome and cardiovascular risks
- Trial name
- NCT04781491
- Testing
- Forest Therapy (Düppeler Forst - Berlin-Wannsee)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Cardiovascular Disease
Impact of Text Messages to Promote Secondary Prevention After Acute Coronary Syndrome
The study is a two-arm, parallel, randomized clinical trial. The purpose of the study is to evaluate the effectiveness of automated mobile phone text message-based intervention for secondary prevention after acute coronary…
- Trial name
- IMPACS (NCT03414190)
- Testing
- Mobile phone text message
- Where
- Brazil
- Volunteers
- 160 people
- Sponsor
- Federal University of Minas Gerais
Prostate Cancer
Cardiovascular Risk and Preventive Care in Prostate Cancer Patients Receiving Radiation and Hormone Therapy
This study will evaluate the proportion of prostate cancer patients receiving external beam radiation therapy (EBRT) and androgen deprivation therapy (ADT) with controlled blood sugars (fasting glucose and hemoglobin A1c), blood…
- Trial name
- NCT02003417
- Where
- 8 sites in United States
- Volunteers
- 101 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cardiovascular Diseases, Cardiovascular Risk Factor
Cooking for Health Optimization With Patients
Cooking for Health Optimization with Patients (CHOP) is the first known multi-site prospective cohort study with a nested Bayesian adaptive randomized trial in the preventive cardiology field of culinary medicine.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Nutrition Disorders, Diabetes
- Trial name
- CHOP (NCT03443635)
- Testing
- Treatment
- Where
- United States
- Volunteers
- 7,192 people, healthy volunteers welcome
- Sponsor
- Tulane University
Coronary Heart Disease, Periodontitis
Changes in the Risk Factors of Coronary Heart Disease Observed After Scaling and Root Planing
The purpose of this study is to determine whether scaling and root planing as a periodontal intervention helps in improving the overall health of patients suffering from coronary heart disease.
- Trial name
- NCT02417376
- Testing
- piezoelectric ultrasonic scaler (frequency of 28-36 KHz), Gracey curettes
- Volunteers
- 70 people
- Sponsor
- Government College of Dentistry, Indore
Mitral Regurgitation, Computed Tomography
Atrial Fibrillation Risk After Miniinvasive Mitral Valve Repair
This retrospective cohort study investigates how CT-derived tissue quality parameters, serving as markers of metabolic status, predict post-operative atrial fibrillation risk in patients undergoing minimally invasive mitral valve…
- Conditions
- Mitral Regurgitation, Computed Tomography, Atrial Fibrillation
- Trial name
- NCT06707506
- Volunteers
- 114 people
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
Metabolic Syndrome, Cardiovascular Disease
Beef in an Optimal Lean Diet (BOLD) Effects on Metabolic Syndrome
The proposed research will provide important information about the role of 2 intervention diets that provide different amounts of lean beef and meet current nutrient recommendations for the treatment of Metabolic Syndrome…
- Trial name
- BOLD-X (NCT00937638)
- Testing
- BOLD Diet, BOLD-X Diet, Modified DASH Diet
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Penn State University
Staphylococcus Aureus Bacteremia, Infective Endocarditis
Evaluation of the Usefulness of Echocardiography in Patients With Staphylococcus Aureus Bacteremia (ET-AUREUS Study).
The goal of this prospective interventionist cohort study is to assess the prevalence of infective endocarditis in patients with Staphylococcus aureus bacteremia at low risk of this complication.
- Trial name
- ET-AUREUS (NCT05862025)
- Testing
- Echocardiography evaluation
- Where
- Spain
- Volunteers
- 470 people
- Sponsor
- Puerta de Hierro University Hospital
Endothelial Dysfunction, Acute Myocardial Infarction (AMI)
Validation of Cor-IS Impedance Spectroscopy Against Ultrasound Flow-Mediated Dilation
This prospective observational study evaluated the Cor-IS bioelectrical impedance spectroscopy technique for the assessment of endothelial function by comparison with ultrasound-based brachial artery flow-mediated dilation (FMD).
- Conditions
- Endothelial Dysfunction, Acute Myocardial Infarction (AMI), Cardiovascular Risk Factors (e.g., Hypertension), Flow Mediated Dilation
- Trial name
- NCT07882550
- Testing
- Cor-IS FMD, Ultrasound FMD
- Where
- Greece
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Schizophrenia, Schizoaffective Disorder
Magnesium Variations and Cardiometabolic Risk in Patients With Antipsychotic Drugs
Background: Antipsychotics can induce metabolic disorders such as obesity, hyperglycemia, dyslipidemia or metabolic syndrome. It has been observed that treatment with antipsychotic could be accompanied by a decrease in the…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
- Trial name
- NCT02986490
- Testing
- Blood sample
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Endothelial Dysfunction
Effect of the HIV Protease Inhibitors Atazanavir and Lopinavir/Ritonavir on Cardiovascular Disease Risk Factors
HIV protease inhibitors (PIs) are a class of antiretroviral drugs used to inhibit viral replication. They do so by interfering with a key step in the replication process.
- Trial name
- NCT00720590
- Testing
- Atazanavir, Lopinavir/ritonavir
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Hypercholesterolemia
Efficacy and Safety Study of Ezetimibe (SCH 58235, MK-0653) in Addition to Atorvastatin in Participants With Coronary Heart Disease or Multiple Cardiovascular Risk Factors (P00693/MK-0653-030)
The overall objective is to evaluate the efficacy and safety of ezetimibe (SCH 058235/MK-0653) 10 mg administered daily in conjunction with atorvastatin in participants with Heterozygous Familial Hypercholesterolemia (HeFH) or in…
- Trial name
- NCT03867318
- Testing
- Atorvastatin, Ezetimibe
- Volunteers
- 621 people
- Sponsor
- Organon and Co
Metabolic Syndrome, Atherosclerosis
Risk Factor Analysis for Developing Metabolic Syndrome in Korean Adults
In Asia, the prevalence of metabolic syndrome have been dramatically increased. Therefore, the investigators intend to the collect the blood sample, laboratory, anthropometric, and body composition parameters prospectively to…
- Trial name
- NCT01594710
- Where
- South Korea
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Korea University
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