Clinical trials: Cardiovascular Disease Risk Factors
Coronary Heart Disease
Feasability of Collaborative Care in the Secondary Prevention of Coronary Heart Disease
The main focus of the pilot study is to evaluate the feasability and effectiveness of a collaborative care intervention for patients suffering from a coronary heart disease (CHD) with insufficient controlled health related risk…
- Trial name
- NCT02389153
- Testing
- collaborative care CHD
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Göttingen
Epilepsy
Impact of Eslicarbazepine Acetate on Lipid Metabolism and Cardiovascular Risk Factors
Knowing the impact that the use of ESL as adjunctive treatment of partial epilepsy has on cardiovascular risk factors measured by biochemical and ultrasound parameters compared with enzyme-inducing AEDs.
- Trial name
- NCT02573272
- Testing
- eslicarbacepine
- Where
- Spain
- Volunteers
- 204 people
- Sponsor
- Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud
Heart Arrest
Unexpected Cardiac Arrest in Intensive Care Unit
Unexpected cardiac arrest involves approximately 0.5 to 5% of patients admitted in Intensive Care Unit (ICU). Even if they have a technical environment conducive to prompt diagnosis and prompt treatment, patients hospitalized in…
- Trial name
- ACIR (NCT03021564)
- Testing
- cardiopulmonary resuscitation
- Where
- 45 sites in France
- Volunteers
- 677 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Cardiomyopathy
Cardiomyopathy Following Stem Cell Transplantation
This study will examine the incidence of cardiac complications, particularly cardiomyopathy, in patients who have undergone allogeneic (donor) stem cell transplantation at NIH.
- Trial name
- NCT00352209
- Where
- 2 sites in United States
- Sponsor
- National Institutes of Health Clinical Center (CC)
Gestational Diabetes Mellitus in Pregnancy, Hypertension ,Pregnancy
Impact of Behavioural Modification Working Toolkit Among Women With Gestational Diabetes Mellitus and Hypertension
This trial aims to evaluate the effectiveness of a Behavioral Modification Working (BMW) Toolkit in improving glycemic control and blood pressure among pregnant women diagnosed with both GDM and PIH.
- Trial name
- NCT07551011
- Testing
- Behavioral Modification Working (BMW) Toolkit, Routine Antenatal Care
- Where
- 2 sites in Pakistan
- Volunteers
- 220 people
- Sponsor
- University of the Punjab
High Blood Pressure, Hypercholesterolemia
Cardiovascular Risk Factors And Intensive Dietary Counselling
The Intensive Dietary Counselling (IDC) intervention is a prevention and health promotion activity. It is being implemented by the Andalusian Health Service to reinforce basic intervention advice on healthy diet and exercise.
- Conditions
- High Blood Pressure, Hypercholesterolemia, Tobacco Smoking
- Trial name
- NCT02173600
- Testing
- Group-level Intensive dietary Counselling, Individual-level Intensive Dietary Counselling
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Andalusian Regional Ministry of Health
Hypercholesterolemia
Intervention With Lupin Protein-enriched Foods in Hypercholesterolemic Subjects
The objective of the study is to elucidate the effects of lupin protein (Lupinus angustifolius Boregine) as part of a mixed diet on cardiovascular risk factors and to clarify the role of arginine, one of the most abundant amino…
- Trial name
- NCT01598649
- Testing
- Fabricated foods with lupin protein, Mannitol, Arginine
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Jena
Pulmonary Hypertension, Pulmonary Hypertension Crisis
Risk Factor Assessment for Acute Pulmonary Hypertension Crisis
The goal of this observational study is to learn about pulmonary hypertension crisis (PHC) - a severe, and often fatal complication - in patients with pulmonary hypertension (PH).
- Trial name
- NCT07653958
- Where
- 4 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Peking Union Medical College Hospital
Diabetes, Depression
INtegrating DEPrEssioN and Diabetes treatmENT (INDEPENDENT) Study
To provide better care and preventive services for people with both depression and diabetes, the investigators propose to develop and test whether interventions to reduce depressive symptoms can be integrated into routine…
- Conditions
- Diabetes, Depression, Cardiovascular Risk Factor
- Trial name
- INDEPENDENT (NCT02022111)
- Testing
- Patient Education and Behavioral Activation, Supporting Self-Care (care coordinators), Psychiatrist and Diabetologist Reviews
- Where
- 4 sites in India
- Volunteers
- 404 people
- Sponsor
- Emory University
Vascular Diseases, Leukoaraiosis
Concentration of Trimethylamine Oxide (TMAO) in Blood Plasma as a Risk Factor for Vascular Cerebral Damage
The primary aim of the current research project is to answer the question, whether plasma trimethylamine N-oxide (TMAO) level may be used as a marker of ischemic changes in the brain.
- Conditions
- Vascular Diseases, Leukoaraiosis, Ischemia, Cerebral
- Trial name
- NCT03903601
- Testing
- Magnetic Resonance Imaging (MRI), Blood samples collection, Neuropsychological tests
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Atherosclerotic Cardiovascular Disease
Association Between Dietary Habits and Risk Factors for Atherosclerotic Cardiovascular Diseases in Assiut Governorate
Studying and investigating the association between dietary habits and risk factors for atherosclerotic cardiovascular diseases in Assiut governorate
- Trial name
- NCT03505073
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Assiut University
Carotid Stenosis
Lifestyle Modification Programme for Patients With Asymptomatic Carotid Artery Stenosis
This study randomises patients with patients with asymptomatic carotid artery stenosis, to be managed either by providing an intensive 12-week lifestyle modification programme, or standard healthcare.
- Trial name
- NCT03929354
- Testing
- Risk Factors Modification Programme, Standard Care
- Where
- Ireland
- Volunteers
- 208 people
- Sponsor
- Western Vascular Institute, Ireland
Cardiovascular Risk Factor, Diabetes Mellitus, Type 1
Cardiopulmonary Testing for Potential Pancreas Transplant Candidates
Patients being assessed for Kidney Pancreas transplantation often have pre-existing co-morbid disease that contributes to structural cardiac and vascular disease.
- Conditions
- Cardiovascular Risk Factor, Diabetes Mellitus, Type 1, Pancreas Transplant; Complications
- Trial name
- NCT04312802
- Testing
- Cardiopulmonary exercise test (CPET)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Oxford University Hospitals NHS Trust
Atherosclerosis
Double-Blind, Randomized, Placebo-Controlled Trial of MLN1202 on C-Reactive Protein Levels in Patients With Risk Factors for Cardiovascular Disease
This study is a, randomized, double-blind, placebo-controlled phase 2a trial evaluating the potential of MLN1202 to reduce circulating levels of C-reactive protein (CRP)in patients with risk factors for Atherosclerotic…
- Trial name
- NCT00715169
- Testing
- MLN1202
- Volunteers
- 108 people
- Sponsor
- Millennium Pharmaceuticals, Inc.
Cardiovascular Risk Factor, Cardiovascular Diseases
Umbrella Review of the DASH Dietary Pattern and Cardiometabolic Risk
The European Association for the Study of Diabetes (EASD) guidelines have not made any specific recommendations regarding the Dietary Approaches to Stop Hypertension (DASH) diet, a dietary pattern that emphasizes fruits and…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Coronary Heart Disease, Stroke
- Trial name
- NCT03542370
- Testing
- DASH dietary pattern
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
HIV Infections
Long-Term Data Collection From Participants in Adult AIDS Clinical Trials
The purpose of this study is to determine what combinations of anti-HIV drugs work best in patients treated over several years. The study will also assess the occurrence of side effects and opportunistic infections in patients…
- Trial name
- NCT00001137
- Where
- 77 sites in United States, Puerto Rico
- Volunteers
- 5,982 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Insulin Sensitivity, Type 2 Diabetes
Effect of Diacylglycerol Oil on Risk Factors of Type 2 Diabetes and Complicating Disease, and Mechanism
Diacylglycerol oil has been shown to lower postprandial and fasting serum triacylglycerol levels and reduce body fat. The investigators hypothesize that replacing dietary fat with diacylglycerol oil reduces excess body fat in…
- Conditions
- Insulin Sensitivity, Type 2 Diabetes, Cardiovascular Disease
- Trial name
- NCT01802541
- Testing
- diacylglycerol oil, triacylglycerol oil
- Volunteers
- 127 people
- Sponsor
- Zhejiang University
Elderly, Hypertension
Prevalence of Sub-Clinical Atrial Fibrillation in Elderly Patients With Hypertension, Detected Using an External Loop Recorder
The ASSERT-III study aims to determine the incidence of sub-clinical (silent) atrial fibrillation (AF) among elderly patients with hypertension and at least one other risk factor for AF.
- Conditions
- Elderly, Hypertension, Risk Factors for Atrial Fibrillation
- Trial name
- ASSERT-III (NCT02401854)
- Where
- 4 sites in Canada
- Volunteers
- 129 people
- Sponsor
- Population Health Research Institute
Obesity, Overweight
Vitamin D Supplementation for the Prevention of Cardiovascular Risk
Hypovitaminosis D is highly prevalent in the general population, particularly in obese individuals. Besides being associated with obesity, vitamin D deficiency seems to be involved in the pathogenesis of insulin resistance and…
- Conditions
- Obesity, Overweight, Insulin Resistance
- Trial name
- NCT02020694
- Testing
- Vitamin D
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cardiac Risk Factors, Cardiovascular Diseases
Dance Therapy as an Alternative for Cardiac Rehabilitation in Women Population
This research project aims to investigate the acute effects of a dance-based cardiac rehabilitation session in the cardiovascular system and autonomic modulation of women with cardiac risk factors.
- Trial name
- NCT04967235
- Testing
- Conventional Exercise-based Cardiac Rehabilitation Session, Dance-based Cardiac Rehabilitation Session
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
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