Clinical trials: Cardiovascular Disease Risk Factors
Postmenopausal Flushing, Cardiovascular Risk Factor
Hot Flash as a Marker of Cardiovascular Risk in Recent Postmenopause: Effects of Non-hormonal Treatments
Hot flashes, vasomotor symptoms that affect many postmenopausal women, are associated with cardiovascular disease and endothelial dysfunction.
- Conditions
- Postmenopausal Flushing, Cardiovascular Risk Factor, Endothelial Dysfunction
- Trial name
- NCT03149419
- Testing
- Paroxetine
- Where
- Brazil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Metabolic Disease, Obesity
Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
Background: Researchers are interested in studying individuals who have known or suspected metabolic, inflammatory or genetic diseases that may put them at a high risk for heart diseases or diseases of their blood vessels.
- Conditions
- Metabolic Disease, Obesity, Li-Fraumeni Syndrome, Cardiomyopathy
- Trial name
- NCT01143454
- Testing
- NSR IDE-MRI: Research pulse sequences
- Where
- 3 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Sneddon Syndrome
Genetic Risk Factors of the Sneddon Syndrome
Sneddon syndrome (SS) is a rare disorder with an incidence of about 4/million/year that affects mainly young and predominantly female adults.
- Trial name
- NCT06850519
- Testing
- Exome Sequencing and Sanger Sequencing
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karl Landsteiner University of Health Sciences
Coronary Artery Disease, Atherosclerosis
Evaluation of Asymptomatic Coronary Atherosclerotic Disease Among People of Kalamazoo, MI
The primary goal of this study is to determine the prevalence of undiagnosed asymptomatic coronary artery disease (CAD) in Kalamazoo and its neighboring areas using Coronary Computed Tomography (CCTA) and Coronary Artery Calcium…
- Trial name
- ESCAPE MI (NCT02942342)
- Testing
- Computed Tomography (CT) Scan
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Borgess Research Institute
Hypertension (HTN), Vascular Diseases
The BASIC-S Feasibility Study for Vascular Risk Reduction
Vascular risk factors drive stroke, heart disease, and dementia, but translating lifestyle guidelines into routine clinical care remains challenging.
- Conditions
- Hypertension (HTN), Vascular Diseases, Stroke, Dementia
- Trial name
- BASIC-S (NCT07755631)
- Testing
- BASIC-S Intervention, Standard / Usual Care
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Andrew Appleton
Atherosclerosis
Effects of Cranberry Juice on Risk Factors for Cardiovascular Disease
This study is being done to determine if the use of double strength cranberry juice in daily diet will improve endothelial function.
- Trial name
- NCT00631306
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Heart Arrest
Unexpected Cardiac Arrest in Intensive Care Unit
Unexpected cardiac arrest involves approximately 0.5 to 5% of patients admitted in Intensive Care Unit (ICU). Even if they have a technical environment conducive to prompt diagnosis and prompt treatment, patients hospitalized in…
- Trial name
- ACIR (NCT03021564)
- Testing
- cardiopulmonary resuscitation
- Where
- 45 sites in France
- Volunteers
- 677 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Cardiovascular Diseases, Heart Diseases
Reanalysis of CVD Risk Factors Via Likelihood Methods
To reanalyze data on risk factors for cardiovascular disease (CVD) including total cholesterol and high density lipoprotein (HDL) cholesterol for the subjects in the first, second, and third exams of the NHLBI Twin Study.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atherosclerosis
- Trial name
- NCT00005408
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypertension, Hyperlipidemia
Prioritized Clinical Decision Support (CDS) to Reduce Cardiovascular Risk
The objective of this project is to develop and implement sophisticated point-of-care Electronic Health Record (EHR)-based clinical decision support that (a) identifies and (b) prioritizes all available evidence-based treatment…
- Conditions
- Hypertension, Hyperlipidemia, Diabetes, Smoking
- Trial name
- NCT01420016
- Testing
- Prioritized Clinical Decision Support
- Volunteers
- 7,914 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Cardiovascular Diseases, Fracture
Prevalence and Risk Factors for Common Diseases
By using national databases in Sweden the aim of the present project is to: 1. Investigate if the incidence of our most common diseases, such as fracture and cardiovascular disease, has changed from 1970-2017 2.
- Conditions
- Cardiovascular Diseases, Fracture, Cancer
- Trial name
- NCT04091035
- Testing
- To describe the incidence of disease and evaluate risk factors
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Anna Nordström
Polycystic Ovary Syndrome
Evaluation of Endocrine and Metabolic Parameters in the New Diagnostic Phenotypes of Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a very frequent endocrine disease of women in reproductive age, with an estimated prevalence of 5 to 10 % according to the studied population.
- Trial name
- NCT00784615
- Testing
- Blood samples, transvaginal ultrasound
- Where
- Argentina
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Córdoba
Colorectal Cancer
Cardiotoxicity and Risk Factors in Patients With Colorectal Cancer Receiving Fluoropyrimidine
observational prospective study, designed for patients with colorectal cancer receiving for the first time 5-FU or capecitabine, with or without other chemotherapy combinations.
- Trial name
- NCT02665312
- Where
- 8 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Smoking
Carotid Plaque Screening Trial in Smokers
The purpose of this study is to determine the impact of carotid plaque screening on smoking cessation and control of other cardiovascular risk factors.
- Trial name
- CAROSS (NCT00548665)
- Testing
- Carotid ultrasound for plaque screening, Brief advice for smoking cessation
- Where
- Switzerland
- Volunteers
- 536 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Hypertension, Hypercholesterolemia
Effects of Purple Vegetables on Cardiovascular Disease (CVD) Risk Factors
The hypothesis is that richly coloured purple vegetables, rich in polyphenolic compounds including anthocyanins will have higher antioxidant and other biological activities, than more lightly coloured versions of these foods.
- Conditions
- Hypertension, Hypercholesterolemia, Type II Diabetes, Obesity
- Trial name
- NCT01564498
- Testing
- vegetable
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Guelph
Asthma, Inflammation
Vascular Implications of a Naturally Occurring Asthma Exacerbation
Although asthma is a disease of the airways, research is now showing that asthmatics are more likely to develop cardiovascular disease (CVD) compared to non-asthmatics.
- Conditions
- Asthma, Inflammation, Cardiovascular Risk Factor
- Trial name
- NCT03679299
- Testing
- Observational - No intervention
- Where
- 2 sites in Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Atherosclerosis
Genetic Factors in Atherosclerosis
The purpose of this study is to identify genes associated with certain risk factors for atherosclerosis (hardening of the arteries) and its consequences, such as development of coronary artery disease, heart attack, other blood…
- Trial name
- NCT00359307
- Where
- United States
- Volunteers
- 1,888 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Deep Venous Thrombosis, Pulmonary Embolism
Risk Factors for Venous Thromboembolism
Deep venous thrombosis is the presence of blood clots, usually in the legs that lead to either local problems or breathing problems if the clot moves to the lungs.
- Trial name
- NCT00018772
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Heart Failure, Diastolic, Heart Failure, Preserved Ejection Fraction
Relative Importance of Cardiovascular Risk Factors and Echocardiographic Parameters Affecting Left Atrial Strain
The goal of this observational study is to learn about left atrial reservoir strain in patients with heart failure with preserved ejection fraction.
- Trial name
- RICH-LAST (NCT05638230)
- Testing
- Left atrial reservoir strain
- Where
- South Korea
- Volunteers
- 2,500 people
- Sponsor
- Yonsei University
Hypercholesterolemia
Effect of Plant Sterols on the Lipid Profile of Patients With Hypercholesterolaemia
Background information Studies have been conducted on supplementing the daily diet with plant sterol ester-enriched milk derivatives in order to reduce LDL-cholesterol levels and, consequently, cardiovascular risk.
- Trial name
- NCT01406106
- Testing
- Plant stanol esters
- Volunteers
- 182 people
- Sponsor
- Gerencia de Atención Primaria, Albacete
Hypertension, Diabetes
Feasibility and Efficacy of Brief Behavior Change Counseling on Lifestyle in Hypertensive and Diabetics Participants
The purpose of this study will be to assess the feasibility and the preliminary efficacy of brief behavior change counseling on lifestyle among diabetic and hypertensive patients
- Conditions
- Hypertension, Diabetes, Life Style
- Trial name
- BBCC+5A's+GS (NCT04625452)
- Testing
- BBCC+5A's+GS
- Where
- Malawi
- Volunteers
- 50 people
- Sponsor
- Kamuzu University of Health Sciences
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