Clinical trials: Cardiovascular Diseases Risk
Cardiovascular Diseases, Coronary Disease
Inflammation, Infection, and Future Cardiovascular Risk
To examine markers of underlying chronic inflammation and infection as potential risk factors for future myocardial infarction (MI), stroke (CVA), and venous thromboembolism (VTE) in plasma samples collected at baseline from…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Cerebrovascular Accident, Myocardial Infarction
- Trial name
- NCT00005496
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Proliferative Diabetic Retinopathy - High Risk
Ultra-Widefield Fluorescein Angiography-Based Targeted Retinal Photocoagulation Versus Conventional Panretinal Photocoagulation in the Preservation of Visual Function and Regression of Proliferative Diabetic Retinopathy
Proliferative diabetic retinopathy is a vision-threatening disease that can lead to irreversible visual loss. The treatment options for proliferative diabetic retinopathy are anti-VEGF injection and retinal photocoagulation.
- Trial name
- NCT06653361
- Testing
- Green laser
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Hayatabad Medical Complex
Dyslipidemia, Angina (Stable)
Validation of Remote Photoplethysmography (rPPG)-Derived Cardiovascular Parameters Against Standard Clinical Measurements and Risk Scores in a Community
The goal of this observational study is to evaluate whether a contactless camera-based technology, called remote photoplethysmography (rPPG), can accurately measure cardiovascular parameters and estimate cardiovascular risk in…
- Conditions
- Dyslipidemia, Angina (Stable), Coronary Artery Disease (CAD), Heart Disease
- Trial name
- NCT07502703
- Where
- Indonesia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Cardiovascular Disease, Acute Kidney Injury
Study to Evaluate the Use of RenalGuard to Protect Patients at High Risk of AKI
The Strength study aim to evaluate the use of the RenalGuard device to protect the patients at high risk to develop acute kidney injury following a complex cardiovascular intervention requiring a high volume of contrast.
- Trial name
- STRENGTH (NCT02793661)
- Testing
- RenalGuard, Control
- Where
- 7 sites in France, Germany
- Volunteers
- 300 people
- Sponsor
- European Cardiovascular Research Center
Heart Failure, Coronary Artery Disease
The Usefulness of Growth Differentiation Factor 15 (GDF-15) for Risk Stratification in Cardiac Surgery
Growth determination factor 15 (GDF-15) and high sensitive troponin-t (hsTnT) are emerging humoral markers for risk stratification in clinically stable heart failure patients and in patients with stable coronary artery disease.
- Trial name
- NCT01166360
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- University of Luebeck
Coronary Artery Disease
Single Dose PCSK9 Inhibitor to Improve Cardiovascular Outcomes After PCI: A Pilot Study
This pilot study aims to evaluate whether a single dose of PCSK9 inhibitor administered after percutaneous coronary intervention (PCI) can improve long-term cardiovascular outcomes in patients with high post-PCI lipid core…
- Trial name
- HANYANG-PICK (NCT07084259)
- Testing
- PCSK9 inhibitor, Standard Lipid-Lowering Therapy
- Volunteers
- 352 people
- Sponsor
- Hanyang University Seoul Hospital
Cardiovascular Disease Risk Factors
Reducing CVD Risk in African Americans Faith Communities
The ultimate goal of our partnership with local African-American churches is to implement an effective, multi-component intervention to increase awareness of the critical importance of healthy lifestyle in the prevention of…
- Trial name
- FAITH! (NCT02235896)
- Testing
- Education/Behavior Modification
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diabetes Mellitus, Type 2, Diabetic Foot
Non-invasive Imaging for In-vivo Quantification of Skin Composition and Structure
The goal of this clinical investigation is to explore a non-invasive technology for measuring the microcirculatory structure, composition and function in patients from a primary care population. The main aims are: 1.
- Conditions
- Diabetes Mellitus, Type 2, Diabetic Foot, Peripheral Arterial Disease, Skin Cancer
- Trial name
- Spectrum1 (NCT06976073)
- Where
- 3 sites in Sweden
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- HJN Sverige AB/Neko Health
Intracerebral Hemorrhage, Thrombectomy
A Novel Score to Predict Risk of Symptomatic Intracerebral Hemorrhage
This study sought to develop and validate a new risk stratification score (Henan predicting the risk of intracerebral hemorrhage score, Henan-PRIHS) based on intra-arterial contrast enhanced Flat Detector CT (IA-CEFDCT) to…
- Conditions
- Intracerebral Hemorrhage, Thrombectomy, Stroke
- Trial name
- NCT04554368
- Testing
- intra-arterial contrast enhanced Flat Detector CT
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Cardiovascular Diseases, Heart Diseases
Visceral Adiposity and CVD Risk in Women
To investigate the influence of total body fat and visceral fat on risk factors of diabetes and cardiovascular disease (CVD) in black and white women.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity, Diabetes Mellitus
- Trial name
- NCT00021879
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiac Disease, Dental Caries
Saliva Profiles in Children With Congenital Heart Disease
The purpose of this study was to evaluate whether there are relationships between the salivary oxidative stress status of children with CHD directly dental caries including gender, age, salivary flow rate, salivary pH, salivary…
- Trial name
- NCT03457974
- Testing
- saliva
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Coronary Artery Disease, Atherosclerosis
Evaluation of Asymptomatic Coronary Atherosclerotic Disease Among People of Kalamazoo, MI
The primary goal of this study is to determine the prevalence of undiagnosed asymptomatic coronary artery disease (CAD) in Kalamazoo and its neighboring areas using Coronary Computed Tomography (CCTA) and Coronary Artery Calcium…
- Trial name
- ESCAPE MI (NCT02942342)
- Testing
- Computed Tomography (CT) Scan
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Borgess Research Institute
Microbial Colonization, Cardiovascular Diseases
Influence of Freeze Dried Strawberry Consumption on Gut Microbiota and Cardiovascular Health.
This proposal seeks to build upon studies, including ours, on the favorable effects of California strawberries on vascular health.
- Conditions
- Microbial Colonization, Cardiovascular Diseases, Obesity
- Trial name
- NCT03283969
- Testing
- Freeze Dried Strawberry Powder, Isocaloric powder
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Pulmonary Embolism
Low Dose Catheter Directed Thrombolysis for Acute Pulmonary Embolism
BETULA trial will compare the efficacy of low dose catheter directed thrombolysis (CDT) to unfractioned heparin (UFH) in patients with intermediary-high risk pulmonary embolism (PE).
- Trial name
- BETULA (NCT03854266)
- Testing
- Low dose alteplase, Unfractionated heparin, Infusion catheter
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Cardiac Arrhythmias
The Efficacy of Adapted Yoga in Managing Psychosocial Risk in Implantable Cardioverter Defibrillator (ICD) Patients
Psychosocial risks are significant in the management of patients with cardiovascular disease and implantable cardioverter defibrillators (ICD) devices. This is a randomized, controlled, clinical study.
- Trial name
- NCT01716351
- Testing
- Adapted Yoga Intervention for Implantable Cardioverter Defibrillator (ICD) Recipients
- Volunteers
- 55 people
- Sponsor
- Yale University
Diffuse Large B Cell Lymphoma, Thrombosis
Thrombosis in Diffuse Large B-cell Lymphoma:the PREDIC-TO (PREDICt ThrOmbosis) Study
Comparative Evaluation of Thrombotic Risk Models in DLBCL patients Objective: To assess the impact of thrombotic risk factors and compare the performance of existing predictive models (Khorana, Throly, Model IX) in Diffuse Large…
- Trial name
- PREDIC-TO (NCT06694779)
- Where
- Italy
- Volunteers
- 1,504 people
- Sponsor
- Fondazione IRCCS San Gerardo dei Tintori
Ventricular Tachycardia, Premature Ventricular Contraction
DOACs for Stroke Prevention Post Ventricular Tachycardia Ablation
The purpose of this study is to learn if taking a drug called direct oral anticoagulant after an ablation procedure keeps blood clots from forming and lowers the chance of having a stroke in patients with ventricular tachycardia…
- Conditions
- Ventricular Tachycardia, Premature Ventricular Contraction, Stroke
- Trial name
- STROKE-VT (NCT02666742)
- Testing
- DOAC, Aspirin
- Where
- 5 sites in United States, India
- Volunteers
- 246 people
- Sponsor
- Kansas City Heart Rhythm Institute
Hypertension, Coronary Disease
Increasing Risk Perception of Physical Activity Using Patient-targeted Feedback.
The aim of this study is to evaluate the efficiency of a minimal intervention on risk perception of physical inactivity in patients with known coronary heart disease (CHD) and patients at risk for CHD.
- Conditions
- Hypertension, Coronary Disease, Cardiac Diseases
- Trial name
- RiskAct (NCT02802254)
- Testing
- Patient-targeted individual physical-activity-feedback, Pedometer
- Where
- 2 sites in Germany
- Volunteers
- 121 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Atherosclerotic Cardiovascular Disease, STEMI
Real Life Lipid Management in Hospitals Not Participating in PENELOPE Trial - Control Population for PENELOPE
Guideline recommended evidence-based clinical care correlates with improved patient outcomes. In real life care, however, adherence to guideline recommendations remains suboptimal.
- Conditions
- Atherosclerotic Cardiovascular Disease, STEMI, Non STEMI
- Trial name
- PENELOPECTRL (NCT05659888)
- Where
- 13 sites in Netherlands
- Volunteers
- 827 people
- Sponsor
- Clinical Operations WCN B.V.
Mild Cognitive Impairment, Alzheimer's Disease
Reducing Risk for Alzheimer's Disease in High-Risk Women Through Yogic Meditation Training
The purpose of this pilot study will be to test whether Kundalini yoga (KY) and Kirtan Kriya (KK) yogic meditation is superior to Memory Enhancement Training (MET) for improving cognitive functioning, health (including…
- Trial name
- NCT03503669
- Testing
- Memory Training, Kundalini yoga and meditation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Los Angeles
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