Clinical trials: Cardiovascular Outcomes
Stroke
Nutrition Blood Outcomes Following Tocotrienol N2B
A natural form of vitamin E called tocotrienol (TCT) has blood thinning and cholesterol lowering properties, both of which may benefit stroke survivors.
- Trial name
- NIIB (NCT01858311)
- Testing
- Tocotrienol Capsules
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Ohio State University
Cerebrovascular Accident
A Post Discharge Intervention to Improve Stroke Outcomes
The purpose of this randomized controlled trial (RCT) is to test the effectiveness of a comprehensive interdisciplinary post-discharge stroke care management intervention in improving the overall well-being of 190 stroke…
- Trial name
- NCT00328471
- Testing
- care management
- Volunteers
- 380 people
- Sponsor
- Summa Health System
Heart Failure, Heart Failure, Systolic
Short-Term Outcomes of HFrEF Patients on Guideline-Directed Medical Therapy
This prospective cohort study aims to evaluate short-term (3-month) clinical, renal, and functional outcomes in patients with heart failure with reduced ejection fraction treated with contemporary guideline-directed medical…
- Trial name
- NCT07821801
- Volunteers
- 250 people
- Sponsor
- Assiut University
Stroke, Gait Impairment
Robot-Assisted Gait Training vs Visual Feedback Balance Training in Stroke
Stroke frequently leads to balance impairment and gait dysfunction, increasing fall risk and limiting functional independence. Technology-assisted rehabilitation approaches such as robot-assisted gait training and visual feedback…
- Conditions
- Stroke, Gait Impairment, Balance Impairment
- Trial name
- NCT07471919
- Testing
- Robot-Assisted Gait Training, Visual Feedback Balance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Abant Izzet Baysal University
Heart Failure, Acute Heart Failure
Telemonitoring Program in the Vulnerable Phase After Hospitalization for Heart Failure
This pragmatic clinical trial aims to evaluate the impact of a telemonitoring program with an electronic alert system compared to standard treatment on the perception of self-care in patients after hospitalization for…
- Trial name
- NCT05972746
- Testing
- Telemonitoring with electronic alerts, Standard of care
- Where
- Argentina
- Volunteers
- 110 people
- Sponsor
- Instituto Cardiovascular de Buenos Aires
Hypertension,Essential
Health Expenses and Outcomes of the DASH Diet in Egyptian Patients With Hypertension
DASH diet can reduce hypertension and decrease health expenses
- Trial name
- NCT06499194
- Testing
- DASH diet
- Where
- Egypt
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Chronic Kidney Diseases, Cardiovascular Diseases
The Leicester City and County Chronic Kidney Disease Cohort
Chronic kidney disease (CKD) is estimated to affect 6-8% of the adult population and is independently associated with increased cardiovascular (CV) disease risk.
- Conditions
- Chronic Kidney Diseases, Cardiovascular Diseases, Cardiovascular Risk Factor
- Trial name
- LCC-CKD (NCT03135002)
- Testing
- Other
- Where
- United Kingdom
- Volunteers
- 25,000 people
- Sponsor
- University of Leicester
Peripheral Artery Disease
Community Walking Exercise for Patients With Peripheral Artery Disease
The primary aim of the study is to determine the effect of a community-based walking exercise program with detailed training, monitoring, and coaching (TMC) exercise components enhanced by community-based participatory research…
- Trial name
- GAIT (NCT02075502)
- Testing
- Exercise therapy, lower extremity ET, peripheral open intervention
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Minnesota
Adherence to Personalized EBM Anticoagulant Treatment in Patients at High Risk for Stroke
Personalized Evidence-based Medicine in Patients With Atrial Fibrillation
A retrospective analysis
- Trial name
- NCT04774341
- Testing
- anticoagulation treatment
- Where
- Russia
- Volunteers
- 4,200 people
- Sponsor
- Center of Personalized Medicine, Pirogova
Acute Myocardial Infarction, Subclinical Depression
SUBDIMA: Subclinical Depression in Acute Myocardial Infarction (SUBDIMA25)
This is an exploratory, prospective, non-profit study (SUBDIMA) designed to investigate the prevalence and potential prognostic significance of subclinical depression in patients admitted with a first acute myocardial infarction…
- Trial name
- SUBDIMA25 (NCT07492537)
- Testing
- Psychological, Cognitive, and Patient-Reported Outcome Assessments
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Caffeine, Exercise Performance
Energy Drink Effects on Performance, Mood, and Cardiovascular Outcomes
Energy drinks are widely promoted to increase energy, enhance mental alertness, and improve physical performance. ccording to the National Center for Complementary and Integrative Health (NCCIH) at NIH [1], next to multivitamins…
- Conditions
- Caffeine, Exercise Performance, Energy Drink, Cardiovascular Safety
- Trial name
- NCT05559372
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Nathaniel Jenkins
Atrial Fibrillation
Registry on WATCHMAN Outcomes in Real-Life Utilization WASP Registry
This is an observational, prospective, non-randomized, multicenter study with the following objectives: (1) to compile real-world clinical outcomes data for WATCHMAN Left Atrial Appendage Closure Technology in patients who are…
- Trial name
- WASP (NCT01972295)
- Where
- 9 sites in Australia, Hong Kong and 5 more
- Volunteers
- 201 people
- Sponsor
- Boston Scientific Corporation
Tricuspid (Valve) Insufficiency (Rheumatic)
PROphylactic triCuspID Annuloplasty in Patients With Dilated Tricuspid Annulus
Patients elected to undergo mitral valve surgery (either repair or replacement) with less equal than moderate (≤+2) tricuspid regurgitation and dilated tricuspid annulus (>21mm/m2) at preoperative echocardiography will be…
- Trial name
- PROCIDA (NCT03129737)
- Testing
- Mitral valve surgery, Tricuspid valve annuloplasty
- Where
- 8 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Ettore Sansavini Health Science Foundation
Diabetes Mellitus, Type 2
RECORD: Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes
This study is a phase 3b, multicentre, randomised, open label, parallel group study. A 4-week run-in period will be followed by a median of 6 years of treatment with study medication in addition to continuation of background…
- Trial name
- RECORD (NCT00379769)
- Testing
- Rosiglitazone, Sulfonylurea, Metformin
- Where
- 446 sites in Australia, Belgium and 23 more
- Volunteers
- 4,447 people
- Sponsor
- GlaxoSmithKline
Thoracic Outlet Syndrome, Mechanically Loaded Neuro-dynamics
Effect of Mechanically Loaded Neuro-dynamics in Subjects With Thoracic Outlet Syndrome
the study was done to: To assess the effect of Mechanically Loaded Neuro-dynamics on pain reduction in subjects with thoracic outlet syndrome.
- Trial name
- NCT07785427
- Testing
- Mechanically Loaded Neuro-dynamics, traditional physical therapy program
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Kafrelsheikh University
Heart Failure
Beta-blOckers discoNtinuation in Patients Presenting Heart FaIlure With REcovered Left Ventricular Ejection Fraction
A significant proportion of patients initially diagnosed with heart failure and a reduced left ventricular ejection fraction (LVEF<40%, HFrEF) presents a substantial improvement in response to evidence-based medical and device…
- Trial name
- BONFIRE (NCT06518694)
- Testing
- Βeta-Blockers discontinued (with tapering)
- Where
- France
- Volunteers
- 1,300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Disease
Impact of IntraVascular UltraSound Guidance on Outcomes of Xience Prime Stents in Long Lesions (IVUS-XPL Study)
This study is designed as a prospective, randomized, multi-center trial to demonstrate an inequality between IVUS-guided versus angiography-guided implantation of everolimus-eluting stents(EES) at long lesions(> 28 mm) in…
- Trial name
- NCT01308281
- Testing
- PCI with IVUS guidance, PCI without IVUS guidance
- Where
- South Korea
- Volunteers
- 1,079 people
- Sponsor
- Yonsei University
Heart Rate, All-day Steps
Assessing the Effect of Cool Roofs on Health Using Smartwatches in Niue
Ambient air temperatures in the Pacific have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Heart Rate, All-day Steps, Distance Walked, Active Minutes
- Trial name
- REFLECT (NCT06571019)
- Testing
- Cool roof
- Where
- Niue
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Ischemic Heart Disease
Randomized Study Comparing Endeavor With Cypher Stents (PROTECT)
The PROTECT TRIAL is a randomized stent trial with 8800 patients in approximately 200 hospitals, which is designed to evaluate whether the Endeavor stent PROTECTS against late stent thrombosis resulting in less deaths and…
- Trial name
- PROTECT (NCT00476957)
- Testing
- Stent
- Where
- Netherlands
- Volunteers
- 8,709 people
- Sponsor
- Medtronic Vascular
Coronary Artery Disease
Rosiglitazone and Metformin: Outcomes Trial in Nondiabetic Patients With Stable Coronary Syndromes (Romance) Pilot Study
Nearly half of all Americans will die from cardiovascular disease caused by the build up of atherosclerotic plaque within coronary arteries.
- Trial name
- NCT00343395
- Testing
- AVANDAMET
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Intermountain Health Care, Inc.
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