Clinical trials: Cardiovascular Outcomes
Stroke
A Psychoeducational Intervention for Stroke Family Caregivers
This is a randomized controlled trial with a 3-month psychoeducational program as intervention, followed by a 3 month observational period.
- Trial name
- NCT02080910
- Testing
- Psychoeducation
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Chinese University of Hong Kong
Acute Stroke, Ischemic Stroke
Impact of Stroke Unit Care on Acute Stroke Outcomes
This observational study is designed to evaluate and compare the recovery outcomes of patients who have experienced their first acute stroke.
- Conditions
- Acute Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- NCT07750860
- Volunteers
- 140 people
- Sponsor
- Assiut University
Cerebral Desaturation, Cerebral Ischemia
Assessment of Cerebral Blood Flow Asymmetry in Cardiac Surgery Patients Undergoing Hypothermic Circulatory Arrest
Cerebral oxygen desaturation during cardiac surgery measured using near infrared spectroscopy (NIRS) derived cerebral oximetry has been associated with significant postoperative morbidity.
- Trial name
- COASTLINE (NCT03215589)
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Cardiovascular Diseases, Cardiovascular Risk Factor
Using Big Data to Conduct Innovative Cardiovascular Clinical Trials
Traditional randomized clinical trials (RCTs) have provided extremely valuable information on medical therapies and procedures that have changed the way heart diseases are treated.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Dyslipidemias
- Trial name
- NCT04067297
- Testing
- Lipid management toolbox
- Where
- Canada
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical Evaluative Sciences
End-stage Heart Failure, Left Ventricular Assist Device
LVAD Index and Clinical Outcomes in Continuous-Flow LVAD Patients
This single-center, observational study evaluated the LVAD index, defined as device-estimated pump flow divided by body surface area, in adult patients supported with continuous-flow left ventricular assist devices.
- Conditions
- End-stage Heart Failure, Left Ventricular Assist Device, Mechanical Circulatory Support
- Trial name
- LVAD-INDEX (NCT07633535)
- Testing
- HeartWare Ventricular Assist Device, HeartMate 3 Left Ventricular Assist Device
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Gaziantep City Hospital
Heart Valve Diseases or Prosthesis, Aortic Valve Stenosis
Comparison of Early Postoperative Outcomes Between Minimally Invasive Valve Surgery Via Right Thoracotomy and Conventional Valve Surgery Via Sternotomy.
This randomized controlled trial aims to compare early postoperative outcomes between Minimally Invasive Valve Surgery (MIVS) via right thoracotomy and Conventional Valve Surgery via median sternotomy in patients undergoing…
- Conditions
- Heart Valve Diseases or Prosthesis, Aortic Valve Stenosis, Aortic Valve Insufficiency, Valvular Heart Disease Stenosis and Regurgitation (Diagnosis)
- Trial name
- NCT07251660
- Testing
- Minimally Invasive Valve Surgery, Conventional Valve Surgery
- Volunteers
- 32 people
- Sponsor
- Chaudhry Pervaiz Elahi Institute of Cardiology
Circulatory Shock, Sepsis
Shock and Acute Conditions OutcOmes Platform
In-hospital mortality of patients admitted in the intensive care unit (ICU) for circulatory shock remains high (between 20 and 40%).
- Conditions
- Circulatory Shock, Sepsis, Cardiogenic Shock, Major Trauma
- Trial name
- ShockCO-OP (NCT06376318)
- Testing
- Inotrope, Mechanical circulatory support, anti-bodies
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- Saint-Louis Hospital, Paris, France
Cardiogenic Shock, IABC Procedure
Intra-aortic Balloon Counterpulsation (IABC) Compliance
The investigators intend to study how baseline arterial compliance (as defined by stroke volume/pulse pressure) influences the clinical success of intraaortic balloon counterpulsation (IABC) in patients with cardiogenic shock…
- Conditions
- Cardiogenic Shock, IABC Procedure, Intraaortic Balloon Counterpulsation (IABC)
- Trial name
- NCT07402018
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Thomas Jefferson University
Shock, Cardiogenic
Clinical Outcomes and Efficacy of Left Ventricular Assist Device for Korean Patients With Cardiogenic Shock
Retrospectively and prospectively enrolled patients with cardiogenic shock in domestic manifolds and investigated the current state of treatment and clinical features of cardiogenic shock in Koreans and identified the factors…
- Trial name
- SMART-RESCUE (NCT02985008)
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Jeong Hoon Yang
Aortic Valve Stenosis, Arrhythmia
Electrophysiological Outcomes After Transcatheter Aortic Valve Replacement
The TAVR-ELECTRO Registry (Electrophysiological Outcomes After Transcatheter Aortic Valve Replacement) is a single-center, observational cohort study designed to systematically evaluate the occurrence, temporal evolution, and…
- Trial name
- TAVR-ELECTRO (NCT07390513)
- Testing
- TAVR Aspirin and clopidogrel
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Myocarditis and Cardiomyopathy
Myocarditis After SARS-CoV2-Vaccination
Background The novel coronavirus disease 2019 (COVID-19) caused by an infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become a global pandemic with more than 190.000.000 infections and…
- Trial name
- MYOVACC (NCT05268458)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Theresien Hospital Mannheim
Coronary Artery Disease
The TEACH (Texting After ACS Discharge) Pilot Randomized Trial
Although there have been substantial advances in the treatment of heart disease, heart attacks remain one of the leading causes of death and suffering around the world.
- Trial name
- NCT05628337
- Testing
- Motivational texting, Control
- Where
- Canada
- Volunteers
- 241 people
- Sponsor
- Sunnybrook Health Sciences Centre
Stroke
Rehabilitation Team Functioning and Patient Outcomes
The purpose of the study is to determine if 1. Rehabilitation staff can be trained to work better together as a team; and 2. Better team work improves patient outcomes.
- Trial name
- NCT00237757
- Testing
- Information feedback
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- US Department of Veterans Affairs
Myocardial Infarction, Diabetes Mellitus, Type 2
SGLT2 Inhibitors on Clinical Outcomes and Left Ventricular Remodeling in Type 2 Diabetic Patients with Acute Myocardial Infarction, a Prospective, Multi-center Registry Study
Prospective trials performed on type 2 diabetes patients without established cardiovascular disease has shown that SGLT2 inhibitors reduce cardiovascular risk.
- Trial name
- RECORD-AMI (NCT05770687)
- Testing
- SGLT2 inhibitor
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Kiyuk Chang
Aneurysmal Subarachnoid Hemorrhage, Endovascular Procedures
Study on Prognosis of Acutely Ruptured Intracranial Aneurysms
The SPARTA study is a prospective multicenter observational trial in the Netherlands with the aim of identifying the best clinical care in patients with aneurysmal subarachnoidal haemorrhage.
- Conditions
- Aneurysmal Subarachnoid Hemorrhage, Endovascular Procedures, Craniotomy, Patient Outcome Assessment
- Trial name
- SPARTA (NCT05851989)
- Where
- 6 sites in Netherlands
- Volunteers
- 880 people
- Sponsor
- Haaglanden Medical Centre
Heart Failure
A Study of Patients Hospitalized With Acute Heart Failure With Reduced Ejection Fraction (HFrEF)
A study of participants hospitalized with acute heart failure with reduced ejection fraction
- Trial name
- NCT03515655
- Where
- United States
- Volunteers
- 99,209 people
- Sponsor
- Bristol-Myers Squibb
Diabetes, Hypertension
The DINE Study-Diet Intervention to Negate Diabetes Study (Improving Weight Loss Outcomes for African Americans)
The purpose of this study is to determine if what you eat affets your insulin sensitivity when you lose a small amount of weight
- Conditions
- Diabetes, Hypertension, Insulin Resistance
- Trial name
- DINE (NCT00599040)
- Testing
- The DASH diet with weight loss, The DASH diet without weight loss, Dairy diet
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Heart Diseases, Cardiovascular Disease
Gauging Outcomes of Total Milk Ingestion on Lipid and gControl
Atherosclerotic cardiovascular disease remains the leading cause of death for adults in the United States. The cardiovascular impact of milk consumption remains a matter of long-standing scientific debate.
- Trial name
- GOT MILC (NCT07087184)
- Testing
- Whole Milk-Skim Milk, Skim Milk-Whole Milk
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Anticoagulant-induced Bleeding, Intracranial Hemorrhages
Anticoagulant-associated Intracranial Hemorrhage
Oral anticoagulant therapy, including factors Xa and 2a inhibitors has become more popular in recent years due to its efficacy and convenience in preventing thrombotic events and reducing the risk for stroke in patients with rosk…
- Trial name
- AAIHINNN (NCT06168838)
- Testing
- Anticoagulant
- Where
- Mexico
- Volunteers
- 1,200 people
- Sponsor
- El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
Myocardial Infarction
Comparison of Myocardial Infarction Patients Who Were Prescribed a Novel Antiplatelet Agent or Clopidogrel
Myocardial infarction is defined according to icd-10 using the data base of South korea National Health Insurance Corporation, where personal identification information has already been removed, and detailed results are derived…
- Trial name
- NCT05599152
- Where
- South Korea
- Volunteers
- 3,000 people
- Sponsor
- Chan Joon Kim
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