Clinical trials: Cardiovascular Outcomes
Heart Diseases
VWCR to Improve Cardiovascular Health and Outcomes Among Cardiac Patients: A Multicenter Randomized Clinical Trial Protocol (Destination Cardiac Rehab Study)
The purpose of this research is to compare health outcomes and participation between a virtual world cardiac rehabilitation (Destination Cardiac Rehab) program and the standard of care Center-based Cardiac Rehabilitation program.
- Trial name
- NCT07745894
- Testing
- Virtual Cardiac Rehabilitation, In-Person Cardiac Rehabilitation
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Mayo Clinic
Coronary Artery Disease
Outcomes, Patient Health Status, and Efficiency in Chronic Total Occlusion
This is an observational registry, sponsored by Saint Luke's Hospital. This study is to be conducted according to DHHS Guidelines, applicable state regulations, and local IRB policies and procedures.
- Trial name
- OPEN-CTO (NCT02026466)
- Where
- 11 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Saint Luke's Health System
Heart Failure
A Psychosocial Dyadic Programme for Patients With Heart Failure and Their Family Caregivers
The overall aim of the study is to evaluate the effects of a psychosocial dyadic intervention on mutuality, psychological strengths (i.e., resilience and self-compassion), psychological distress (i.e., anxiety and depression)…
- Trial name
- NCT05864469
- Testing
- 12-week psychosocial dyadic intervention
- Where
- China
- Volunteers
- 192 people
- Sponsor
- The University of Hong Kong
Coronary Artery Disease, Atherosclerosis
Drug-eluting Balloon in Bifurcations Trial
The purpose of the DEBIUT study is to assess procedural, clinical and angiographic outcomes of: 1. Provisional T-stenting use for dilation the Paclitaxel-eluting PCI-balloon (DiorTM) in comparison to dilation with a standard…
- Conditions
- Coronary Artery Disease, Atherosclerosis, Stable Angina, Unstable Angina
- Trial name
- DEBIUT (NCT00857441)
- Testing
- Drug eluting balloon, Liberté, PTCA balloon catheter
- Where
- 3 sites in Belgium, Netherlands
- Volunteers
- 120 people
- Sponsor
- UMC Utrecht
Cardiac Arrest (CA)
Treatment Outcome in Patients After eCPR
This study consists of two parts - retrospective and prospective. The aim of this study is to assess the quality of life in bio-psycho-social dimensions in patients after eCPR (extracorporeal cardiopulmonary resuscitation), in…
- Trial name
- NCT07031466
- Testing
- Retrospective analysis of assigned treatment, Quality of Life (SF-36), Quality of Life (EQ-5D)
- Where
- 2 sites in Czechia
- Volunteers
- 74 people
- Sponsor
- University Hospital Ostrava
Cardiogenic Shock, Extracorporeal Life Support
Post-Surgery Extracorporeal Life Support
Extracorporeal Life Support (ECLS) may provide pulmonary and circulatory support for patients with acute heart failure refractory to conventional medical therapy.
- Conditions
- Cardiogenic Shock, Extracorporeal Life Support, Extracorporeal Membrane Oxygenation Complication, Post Cardiac Arrest Syndrome
- Trial name
- PC-ECLS (NCT04330651)
- Testing
- ECLS
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Florence
Type 2 Diabetes, Systolic Hypertension
Blood Pressure Outcomes With Liraglutide Therapy
Purpose: The purpose of this study is to further study the mechanism by which liraglutide, a relatively new anti-hyperglycemic medication, might lower blood pressure in patients with Type 2 diabetes and high blood pressure.
- Trial name
- BOLT (NCT01755572)
- Testing
- Liraglutide
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Mount Sinai Hospital, Canada
Pulmonary Arterial Hypertension, Air Pollution
The Risk of Adverse Pregnancy Outcomes for Long-term Exposure to Air Pollution in Pregnant Patients With Pulmonary Hypertension
With economic development and rapid urbanization, air pollution has become an increasingly severe public health concern. The risk of adverse pregnancy outcomes is significantly elevated for pregnant women complicated by pulmonary…
- Conditions
- Pulmonary Arterial Hypertension, Air Pollution, Maternal Outcome
- Trial name
- NCT07164157
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Wei Huang
Cerebrovascular Accident, Transient Ischemic Attack
Safety Study of Atomoxetine and Cerebrovascular Outcomes
Using a proprietary insurance health claims database, Eli Lilly and Company has contracted with an external party to conduct a retrospective cohort study of health claims for the time period from 1 January 2003 through 31…
- Conditions
- Cerebrovascular Accident, Transient Ischemic Attack, ADHD
- Trial name
- NCT00634439
- Testing
- atomoxetine, Stimulants, No intervention (general population)
- Where
- United States
- Volunteers
- 72,000 people
- Sponsor
- Eli Lilly and Company
Congestive Heart Failure
Utility of Serial BNP Levels in Emergency Department CHF
The purpose of the study is to determine if a series of BNP blood tests performed on patients who present to the Emergency Department with congestive heart failure (CHF) can predict which patients may have adverse outcomes.
- Trial name
- NCT00534066
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Ohio State University
Overweight, Obesity
Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity in the Real World
This is a retrospective database study which includes administrative medical and pharmacy claims linked with clinical and laboratory measurements for patients in the US, to evaluate the effectiveness of once-weekly semaglutide…
- Conditions
- Overweight, Obesity, Atherosclerotic Cardiovascular Disease (ASCVD)
- Trial name
- SCORE (NCT06874751)
- Testing
- No treatment given
- Where
- United States
- Volunteers
- 45,456 people
- Sponsor
- Novo Nordisk A/S
Atrial Fibrillation
Transcutaneous (Tragus) Vagal Nerve Stimulation for Post-op Afib
Patients undergoing cardiac surgery are at high risk of developing atrial fibrillation (AF), with estimated rates of 30-50% and occurs at approximately 2-4 days after surgery.
- Trial name
- STOP_AF (NCT04514757)
- Testing
- active tVNS
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- University of California, Los Angeles
Aneurysmal Subarachnoid Hemorrhage
Admission Bio-clinical Score to Predict One-year Outcomes in Coiled Subarachnoid Hemorrhage (SAH)
The goal of this observational study is to develop and validate a predictive score of 1-year outcomes in subarachnoid hemorrhage (SAH) patients receiving aneurism coiling.
- Trial name
- ABCSAH (NCT01357057)
- Where
- France
- Volunteers
- 530 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocardial Infarction, Heart Failure
Randomized Controlled Cluster Trial of Resident Pay for Performance and Cardiovascular Outcomes
The purpose of this study is to determine if a pay for performance model in contrast to the traditional "fee for service" model may improve the number of patients discharged being treated in accordance with Joint Commission on…
- Trial name
- NCT01590290
- Testing
- financial compensation
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Virginia
Pulmonary Hypertension (Diagnosis), Pre-operative Assessment
GUARD-PH: Guided Use of AI-ECG for Risk Detection of PH in Surgery (GUARD-PH Trial)
This study is a prospective, open-label, randomized controlled trial designed to evaluate a new artificial intelligence (AI) tool for heart monitoring.
- Conditions
- Pulmonary Hypertension (Diagnosis), Pre-operative Assessment, Postoperative Complications (Cardiopulmonary), Treatment Outcomes
- Trial name
- GUARD-PH (NCT07344207)
- Testing
- Artificial Intelligence-Enabled Electrocardiography System
- Where
- Taiwan
- Volunteers
- 1,380 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Atrial Fibrillation New Onset, New Onset Atrial Fibrillation
Tracking Atrial Fibrillation After Intensive Care Admission
Atrial fibrillation (AF) is a heart problem that causes an irregular heartbeat. It can cause the heart to beat more rapidly and reduce the heart's ability to pump blood around the body efficiently, causing heart failure.
- Conditions
- Atrial Fibrillation New Onset, New Onset Atrial Fibrillation, Atrial Fibrillation
- Trial name
- TrAFFIC (NCT05229211)
- Testing
- Cardiac monitoring
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Oxford
Acute Coronary Syndromes
Cocktail Injection Improves Outcomes of FFR Guided PCI
This is a randomized, single blind, controlled study of intracoronary cocktail injection before fractional flow reserve (FFR) measurement when guiding percutaneous coronary intervention (PCI) in patients with acute coronary…
- Trial name
- CocktailII (NCT02592720)
- Testing
- cocktail, FFR, QCA guided group
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xijing Hospital
Varicose Veins
The Effect of Laser Power and Fiber Traction Speed on the Outcomes of Endovenous Laser Ablation
A multicenter clinical randomized controlled trial, comparing of three different regimens of endovenous laser ablation with equal linear endovenous energy density in patients with insufficiency of the great saphenous vein (GSV).
- Trial name
- SLEDGE (NCT03037827)
- Testing
- Endovenous laser ablation (EVLA), Laser
- Where
- 2 sites in Russia
- Volunteers
- 203 people
- Sponsor
- Clinic of Phlebology and Laser Surgery, Chelyabinsk, Russia
Thrombotic Thrombocytopenic Purpura (TTP), Immune Thrombotic Thrombocytopenic Purpura
Retrospective Epidemiological Study of Patients in the National Cohort of the French TMA Center
Immune thrombotic thrombocytopenic purpura (iTTP) is a rare, life-threatening disorder characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and ischemic organ damage due to microvascular thrombosis.
- Conditions
- Thrombotic Thrombocytopenic Purpura (TTP), Immune Thrombotic Thrombocytopenic Purpura, Thrombotic Microangiopathies, Microangiopathy, Thromboic
- Trial name
- TWILIGHT (NCT07205861)
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus, Hypertension
Use of Low-cost mHealth Intervention to Enhance Outcomes of Noncommunicable Diseases Care in Rural and Refugee Settings
Rural areas and refugee camps are characterized by poor access of patients to needed noncommunicable disease (NCD)-related health services, including diabetes and hypertension.
- Trial name
- NCT03580330
- Testing
- mHealth intervention
- Volunteers
- 2,359 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.