Clinical trials: Cardiovascular Outcomes
Hip Disease, Heart Failure
How Does Patients' Overall Assessment of Their Health Vary Across and Within Different Disease Groups?
EQ-5D is one of the most commonly employed patient-reported outcome (PRO) measures. It is included in many of the Swedish National Quality Registers (NQRs).
- Conditions
- Hip Disease, Heart Failure, Psoriasis, Fractures, Bone
- Trial name
- SWEQR (NCT04359628)
- Where
- Sweden
- Volunteers
- 700,000 people
- Sponsor
- Vastra Gotaland Region
Malignant Neoplasms of Female Genital Organs
Pneumoperitoneum Management With Low vs. Higher Pressure
The goal of this clinical research study is to compare the level of pain 2 hours after surgery in patients after the use of the AirSeal® Insufflation System (AIS) at a high or low pressure setting or the standard insufflator (the…
- Trial name
- NCT03128281
- Testing
- Questionnaires, Conventional Insufflation System (CIS), ConMed AirSeal Insufflation System (AIS) at Low Pressure
- Sponsor
- M.D. Anderson Cancer Center
Cardiovascular Diseases, Heart Diseases
Outcomes of Sleep Disorders in Older Men
To determine the effects of sleep disorders on cardiovascular function and disease in older men.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Sleep, Sleep Apnea Syndromes
- Trial name
- NCT00070681
- Testing
- Polysomnography
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Multiple Myeloma
Multiple Myeloma Outcomes Based on Maintenance Therapy Post Autologous Stem Cell Transplant
The purpose of the study is to determine outcomes for Multiple Myeloma patients on maintenance single agent vs. doublet (IMiD + PI) combination chemotherapy post Autologous Stem Cell Transplant (ASCT).
- Trial name
- NCT05271630
- Testing
- Autologous Stem Cell Transplant, Immunomodulatory Agent, Proteasome Inhibitor
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Cardiac Arrest, Out-Of-Hospital, Ketamine
The Application of Ketamine for Sedation in Patients With Cardiac Arrest - - KetCat (KETamine in Cardiac ArresT) Study
Recent evidence suggests ketamine may attenuate harmful cellular cascades taking place after brain injury that result in permanent damage.
- Conditions
- Cardiac Arrest, Out-Of-Hospital, Ketamine, Neurologic Manifestations
- Trial name
- KetCat (NCT04360070)
- Testing
- Ketamine Hydrochloride
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Fraser Health
Thoracoabdominal Aortic Aneurysm
Thoracoabdominal Aortic Aneurysms
Evaluation of the effectiveness of the different modalities for treatment of thoracoabdominal aortic aneurysms. FEVAR and BEVAR devices are widely used now due to its feasability and wide range of use .
- Trial name
- NCT06267573
- Testing
- Fenestrated and branched endovascular devices for TAAA
- Volunteers
- 100 people
- Sponsor
- Assiut University
Diabetic Foot Disease, Diabetic Foot Infection
Intraosseous Versus Intravenous Vancomycin in Below-Knee Amputation for Ischemic Diabetic Foot
This randomized clinical trial compared two routes of vancomycin administration in patients undergoing below-knee amputation for ischemic diabetic foot infection.
- Conditions
- Diabetic Foot Disease, Diabetic Foot Infection, Diabetic Amputation Foot Wound
- Trial name
- NCT07338773
- Testing
- Intraosseous Vancomycin, Intravenous Vancomycin
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Cardiovascular Complication, Complication, Postoperative
Perioperative Endothelial Dysfunction in Patients Undergoing Major Acute Abdominal Surgery
The aim of the clinical study is: 1. to examine the association between postoperative endothelial function, indirectly measured by reactive hyperemia index, and major adverse cardiovascular events including myocardial injury and…
- Trial name
- POETRYabd (NCT03010969)
- Testing
- Acute abdominal surgery
- Where
- Denmark
- Volunteers
- 224 people
- Sponsor
- Zealand University Hospital
Heart Failure
Risk Factors of Outcomes Associated With Disease Progression in Patients With Atrial Fibrillation and Heart Failure (HF) Who Are Receiving a Direct Oral Anticoagulant (Rivaroxaban)
Evaluation of the risk factors associated with Heart Failure (HF) worsening (measured by hospitalizations and emergency visits because of HF exacerbations) in Spanish patients with Atrial Fibrilation and HF treated with…
- Trial name
- FARAONIC (NCT03455439)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- Spain
- Volunteers
- 552 people
- Sponsor
- Bayer
Aorta Dissection, Aorta Aneurysm
Hybrid Operation in Thoracic Aortic Dissection
The purpose of this study is to investigate the short to mid term efficacy and safety of different hybrid operations who had complex aortic lesions, such as ascending aortic/arch aneurysm, pseudo-aneurysm, Stanford Type A…
- Trial name
- NCT01500395
- Testing
- Hybrid operation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Multiple Myeloma, Relapsed Hematologic Malignancy
PRO and Wearable Data Insights From Individuals With R/R Multiple Myeloma
This study will evaluate the feasibility of a digital health coaching program for adults with relapsed or refractory multiple myeloma (R/R MM). One hundred adults with R/R MM will be enrolled at The University of Washington.
- Trial name
- NCT05956457
- Testing
- Digital Health Coaching Program, Fitbit
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Pack Health
Preeclampsia, Gestational Hypertension
Serum Vasohibin, Cardiotrophin, Endocan & Perinatal Outcomes
Investigation of the relationship between maternal serum vasohibin-1, vasohibin-2, cardiotrophin -1 and endocan concentrations at the 11th and 14th weeks of gestation and adverse perinatal outcomes.
- Conditions
- Preeclampsia, Gestational Hypertension, Gestational Diabetes, Preterm Birth
- Trial name
- NCT06416995
- Testing
- first trimester serum diagnostic test
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Umraniye Education and Research Hospital
Coronary Heart Disease
An mHealth Intervention to Improve Medication Adherence and Health Outcomes
Investigators evaluated the efficacy of a pilot-tested mHealth intervention to improving medication adherence and health outcomes among patients with coronary heart disease.
- Trial name
- NCT04703439
- Testing
- Medication-taking reminders & educational materials, Educational materials
- Where
- China
- Volunteers
- 230 people
- Sponsor
- Duke University
Cardiac Ischemia, Acute Coronary Syndrome
Instantaneous Wave-free Ratio Guidance Strategy Evaluation in the Treatment of Multivessel Acute Coronary Syndrome.
A single-center, prospective, randomized, open-label, blinded end-point clinical trial of instantaneous wave-free ratio (iFR) guidance strategy impact on clinical outcomes in multivessel acute coronary syndrome (ACS) patients.
- Trial name
- iStrategy (NCT05006183)
- Testing
- PCI
- Where
- Latvia
- Volunteers
- 150 people
- Sponsor
- Daugavpils Regional Hospital
Coronary Artery Disease
Prospective Registry to Assess the Cath Lab Percutaneous Coronary Intervention Long-term Outcomes: a Single Center
The registry study is to obtain the state of the percutaneous coronary intervention state treatment for coronary heart disease in the center of the first hospital of sun yat-sen unversity in a real world.
- Trial name
- PCI-registry (NCT02498470)
- Testing
- percutaneous coronary intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Xiao-dong Zhuang
Stroke, Stroke, Acute
Frequency vs Error Augmentation Training in Acute Physical Therapy Post Stroke
The Department of Physical Therapy in conjunction with the Comprehensive Stroke Center at the Medical University of South Carolina (MUSC) seeks support for developing an evidence-based approach for the mobilization of patients…
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic
- Trial name
- FEAT (NCT06042179)
- Testing
- Frequent PT, Intense PT
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Medical University of South Carolina
Acute Coronary Syndrome
The Stabilization Of pLaques usIng Darapladib-Thrombolysis In Myocardial Infarction 52 Trial
This study will test whether darapladib can safely lower the chances of having a cardiovascular event (such as a heart attack or urgent coronary revascularization (e.g.
- Trial name
- SOLID-TIMI 52 (NCT01000727)
- Testing
- Darapladib 160 mg, Standard Therapy
- Where
- 914 sites in United States, Argentina and 34 more
- Volunteers
- 13,026 people
- Sponsor
- GlaxoSmithKline
Hypertensive Disorders of Pregnancy, Chronic Hypertension in Pregnancy
MH-Rx Study (Baby on Board: Check-in on You, Your Medication, & Your Blood Pressure)
This randomized controlled trial will evaluate whether adding Community Health Worker (CHW)/Social Worker (SW)-led support for non-medical health related needs (NMHRN) and clinician-led Medication Therapy Management (MTM) to…
- Conditions
- Hypertensive Disorders of Pregnancy, Chronic Hypertension in Pregnancy, Gestational Hypertension
- Trial name
- NCT07842341
- Testing
- Community Health Worker (CHW)/Social Worker (SW)-led non-medical health related needs (NMHRN) intervention + Clinician-Led Medication Therapy Management (MTM) with remote blood pressure monitoring, Active Comparator (Control group)
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Texas Southern University
Diabetic Retinopathy, Lasers
Pattern Scanning Laser Pan-retinal Photocoagulation in Proliferative Diabetic Retinopathy
A randomized study to assess the safety and efficacy of single-session pan-retinal photocoagulation (PRP) using Pattern Scan Laser (PASCAL) in proliferative diabetic retinopathy (PDR) - 1,700 shots vs 2,500 shots
- Conditions
- Diabetic Retinopathy, Lasers, Treatment Outcome
- Trial name
- NCT02816073
- Testing
- Pan-retinal photocoagulation using pattern scanning laser
- Volunteers
- 17 people
- Sponsor
- United Christian Hospital
Hypertension, Pulmonary
Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension
The TOPP-2 registry is an international, non-interventional, prospective registry including children and adolescents newly diagnosed with pulmonary hypertension (PH) to gain further insights in the disease course and long-term…
- Trial name
- TOPP-2 (NCT02610660)
- Where
- 32 sites in United States, Australia and 16 more
- Volunteers
- 388 people
- Sponsor
- Association for Pediatric Pulmonary Hypertension
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