Clinical trials: Cardiovascular Outcomes
Focal Segmental Glomerulosclerosis
LDL-Apheresis for FSGS CardioRenal Outcomes
Focal segmental glomerulosclerosis (FSGS) is the most common cause of end-stage renal disease (ESRD) in adolescents. The refractory nature of FSGS and a more than 30% recurrence rate after kidney transplantation renders treatment…
- Trial name
- NCT04088799
- Testing
- No intervention
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Stroke
Creative Therapy to Affect Stroke Outcomes
Stroke is one of the common diseases in the elderly. It is the third ranking cause of death and affects health care system in our country.
- Trial name
- NCT01455155
- Testing
- Creative therapy (art and music therapy), Physical therapy
- Where
- Thailand
- Volunteers
- 204 people
- Sponsor
- Mahidol University
Cardiovascular Diseases, Cancer
Relationship Between Dietary Protein Intake and Fatal and Non-fatal Health Outcomes
The aim of the current study was to clarify the relationship between protein intake and health by using a very large, general population cohort study, UK Biobank, to study the associations between reported protein intake…
- Conditions
- Cardiovascular Diseases, Cancer, All-cause Mortality
- Trial name
- NCT03243578
- Testing
- None as this is an observational study
- Volunteers
- 502,628 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Coronary Heart Disease, Dyslipidemia
The Hellenic Postprandial Lipemia Study (HPLS)
Coronary heart disease (CHD) is the leading cause of death worldwide. The disease is characterized by a high mortality rate (about 40%) and a course continuously altered by lifestyle, gene polymorphisms and therapeutic treatment.
- Trial name
- HPLS (NCT02163044)
- Where
- Greece
- Volunteers
- 580 people
- Sponsor
- Hellenic College of Treatment of Atherosclerosis
Tricuspid Regurgitation, Right Heart Failure
Pforzheim Tricuspid Valve Registry - Outcomes of Percutaneous Tricuspid Valve Repair
The Pforzheim Tricuspid Valve Registry study is designed to confirm the safety and performance of the TriClip™ device in a contemporary real-world setting in critically ill patients.
- Conditions
- Tricuspid Regurgitation, Right Heart Failure, Cardiac Remodeling, Ventricular, Cardiac Remodeling, Atrial
- Trial name
- NCT05179616
- Testing
- Transcatheter edge-to-edge tricuspid valve repair
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Helios Klinikum Pforzheim
Diabetes Mellitus, Type 2
A Study Using Medical Records of Danish People With Type 2 Diabetes Comparing Empagliflozin and Glucagon-Like Peptide-1 Receptor Agonists (GLP1-RA) in the Occurrence of Serious Cardiovascular Outcomes
The primary research question is to evaluate whether, among patients with type 2 diabetes mellitus (T2D), initiation of empagliflozin changes the adjusted incidence of outcomes compared with initiation of Glucagon-Like Peptide-1…
- Trial name
- NCT03993132
- Testing
- Empagliflozin, Liraglutide
- Where
- Denmark
- Volunteers
- 26,774 people
- Sponsor
- Boehringer Ingelheim
Atrial Fibrillation
Left Atrial Low vOltage Zone, GenetIC Markers and Outcomes in Patients After Atrial Fibrillation abLation
This prospective, single-centre cohort study aims to investigate the association between known genetic Atrial Fibrillation (AF) risk variants and the amount of left atrial fibrosis found in patients undergoing clinically…
- Trial name
- LOGICAL (NCT02074826)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Technische Universität Dresden
Coronary Artery Disease, Inflammatory Response
Efficacy of Dexamethasone to Improve Clinical Outcomes in Coronary Artery Bypass Patients
This is a single-center, double-blind, randomized controlled clinical trial comparing four groups: placebo conventional coronary artery bypass graft (CCABG) group, dexamethasone CCABG group, placebo off-pump coronary artery…
- Trial name
- NCT05487508
- Testing
- Dexamethasone, Normal saline
- Where
- Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
Stroke, Parkinson Disease
C-STAR Movement Database
The purpose of this study is to develop a database that contains movement and rehabilitation-related data collected through the use of wearable sensors and video.
- Conditions
- Stroke, Parkinson Disease, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury)
- Trial name
- NCT05471375
- Testing
- Database Entry
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Shirley Ryan AbilityLab
Heart Failure, Cancer
M. D. Anderson Symptom Inventory - Heart Failure (MDASI-HF) Symptom Management Program
Primary Objective: To determine if there is a reduction in the mean symptom severity scores for the heart failure specific symptom items between baseline and at the end of three months between patients whose symptoms are managed…
- Trial name
- NCT00827801
- Testing
- MDASI-HF Questionnaire
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- M.D. Anderson Cancer Center
Disease, Cardiovascular Diseases
Biomarkers of Acrylamide, Glycidol, POPs, PFAS and Disease Outcomes and OMICs Signatures
The aim of the project is to assess the associations between biomarkers of acrylamide and glycidol exposure and disease outcomes in a case-cohort study based on two prospective cohorts with biobanks.
- Conditions
- Disease, Cardiovascular Diseases, Cancer, Environmental Exposure
- Trial name
- NCT05930626
- Testing
- Biomarkers of acrylamide, glycidol, POPs, PFAS
- Volunteers
- 9,254 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Coronary Heart Disease
"Nutrition Education by Nurses in Patients After Coronary Artery Bypass Grafting: Effect on Patients' Dietary Pattern, Adherence and Clinical Outcomes"
The purpose of this study is the investigation of the effect of nurse-led nutritional education of post-CABG patients on their dietary pattern, on their adherence to it, but also on their quality of life and well-being.
- Trial name
- NCT07172906
- Testing
- Patients of Group A and B both are filling out the questionnaire "Mediterranean diet questionnaire (MEDAS)", Patients of Group A and B both are filling out the "Mini Nutritional Asessment" questionnaire, Patients of Group A and B both are filling out "Nottingham Health Profile Scale" questionnaire
- Volunteers
- 160 people
- Sponsor
- Hellenic Mediterranean University
Cerebral Venous Thrombosis
Treatment Outcomes of Direct Oral Anticoagulants in Cerebral Venous Thrombosis in Vietnam
This prospective, single-arm observational cohort study aims to evaluate the real-world effectiveness and safety of direct oral anticoagulants (DOACs), specifically dabigatran or rivaroxaban, in patients with cerebral venous…
- Trial name
- DCVT-VN25 (NCT07083609)
- Testing
- Dabigatran, Rivaroxaban
- Where
- Vietnam
- Volunteers
- 69 people
- Sponsor
- Hieu Trung Dinh
Health Promotion, Cardiovascular Health
Health Impact 360: Advancing Physical, Social, and Mental Health Toward Cardiovascular Disease Prevention in Community Settings
The purpose of this clinical trial is to evaluate an evidence-based intervention, Health Impact 360, toward the promotion of cardiovascular health (CVH), including physical, mental, and social health outcomes, among adults living…
- Trial name
- HI360 (NCT07034352)
- Testing
- Health Impact 360, Usual care - Wait list control
- Where
- 7 sites in United States
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- University of Michigan
miRNA
Circulating microRNAs and Adverse Cardiovascular Outcomes in Patients With Coronary Artery Disease
Coronary artery disease (CAD) resulting from atherosclerotic obstruction of epicardial coronary arteries accounts for more than one-third of deaths in subjects over the age of 35 worldwide.
- Trial name
- NCT03635255
- Where
- Taiwan
- Volunteers
- 460 people
- Sponsor
- National Taiwan University Hospital
Stroke
Patient Reported Outcomes in Stroke Care
The presented study is an explorative prospective study. First, it focusses on the longitudinal analysis of outcome quality in stroke treatment (12 months).
- Trial name
- EPOS (NCT03795948)
- Testing
- PROMs
- Where
- Germany
- Volunteers
- 975 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Healthy, Healthy Subjects (HS)
Static Stretching Reshapes Post-RT Recovery
This experimental study investigates the acute cardiovascular and local recovery to a single session of resistance training, with and without additional static stretching, compared with a resting control condition.
- Conditions
- Healthy, Healthy Subjects (HS), Cardiovascular Adaption, Stretching
- Trial name
- NCT07649785
- Testing
- Resistance Training, Resistance training + Static Stretching
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Venous Thrombosis, Pulmonary Embolism
Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)
This prospective cohort study will provide information about: characteristics of Rivaroxaban use in patients who are prescribed Rivaroxaban for the first time compared to patients who are prescribed Warfarin for the first time…
- Conditions
- Venous Thrombosis, Pulmonary Embolism, Atrial Fibrillation, Acute Coronary Syndrome
- Trial name
- NCT01947998
- Testing
- Rivaroxaban (Xarelto, Bay59-7939), Warfarin, Antiplatelet drugs
- Where
- United Kingdom
- Volunteers
- 50,299 people
- Sponsor
- Bayer
Intracranial Atherosclerosis
Short- and Long-term Outcomes of Stenting for Symptomatic Intracranial Arterial Stenosis: a Cohort Study
The purpose of this study is to assess short and long term outcomes of stenting for symptomatic intracranial arterial stenosis.
- Trial name
- NCT05203887
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Sohag University
Aortic Stenosis
Anatomical Determinants and Outcomes of Small Annulus Patients Undergoing TAVR in Different ASIAN Ethnicity
Transcatheter aortic valve implantation (TAVI) presents unique challenges for Asian patients compared to Caucasians, largely due to the prevalence of small aortic annulus (SAA) defined based on Caucasians' data (430 mm²)…
- Trial name
- NCT07240025
- Where
- Hong Kong
- Volunteers
- 31 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong
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