Clinical trials: Cardiovascular Outcomes
Stroke
Effects of Inspiratory Muscle Training on Stroke Rehabilitation Outcomes
This study is designed to explore the effects of a 4-week protocol of inspiratory muscle training (IMT) at 50% maximum inspiratory pressure (MIP) on respiratory function, diaphragm thickness, balance control, exercise capacity…
- Trial name
- NCT06640101
- Testing
- IMT-stable group (sitting on a stable surface), IMT-unstable group (sitting on an unstable surface), Conventional treatment
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Hong Kong Metropolitan University
Myocarditis, Pericarditis
A Study on the Clinical Course, Outcomes and Risk Factors of Myocarditis and Pericarditis After Moderna COVID-19 Vaccine
The main goal of this study is to describe the clinical course, outcomes and risk factors for myocarditis and pericarditis associated with Moderna vaccination targeting SARS-CoV-2.
- Trial name
- NCT06113692
- Testing
- mRNA-1273
- Where
- 5 sites in Denmark, Norway and 2 more
- Volunteers
- 1,169 people
- Sponsor
- ModernaTX, Inc.
Cardiovascular Diseases, Heart Failure
Clinical Outcomes of Cardiovascular Disease
This study is a prospective, single center cohort study that primarily registers the clinical characteristics, outcomes, and influencing factors of patients with different types of cardiovascular diseases.
- Conditions
- Cardiovascular Diseases, Heart Failure, Coronary Artery Disease
- Trial name
- CLEAR (NCT06459934)
- Where
- China
- Volunteers
- 30,000 people
- Sponsor
- Xinjiang Medical University
Peripheral Arterial Disease, Quality of Life
Patient-centered Outcomes Related to TReatment Practices in Peripheral Arterial Disease: Investigating Trajectories (PORTRAIT)
An estimated 8 million individuals in America are affected by peripheral arterial disease (PAD), blockages of the leg arteries that can cause excruciating calf pain when walking.
- Conditions
- Peripheral Arterial Disease, Quality of Life, Quality of Care
- Trial name
- PORTRAIT (NCT01419080)
- Where
- 10 sites in United States
- Volunteers
- 797 people
- Sponsor
- Saint Luke's Health System
ST Elevation (STEMI) Myocardial Infarction
LA Strain in Predicting Early Complication in STEMI After PPCI
The goal of this observational study To evaluate the predictive value of left atrial strain for in-hospital outcomes in patients with ST-segment elevation myocardial infarction undergoing PPCI.
- Trial name
- NCT07263282
- Testing
- 2D echocardiography
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Assiut University
Post-Traumatic Stress Disorder, Depression
Long Term Health Outcomes of Women Veterans' Service During the Vietnam Era
Little is known about the long-term health and mental health status of women Vietnam veterans. For many of these women, the effects of this war are still present in their daily lives.
- Conditions
- Post-Traumatic Stress Disorder, Depression, Diabetes, Cardiovascular Disease
- Trial name
- Health ViEWS (NCT00958061)
- Where
- United States
- Volunteers
- 4,219 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Heart Failure
Food Supplementation Delivered Conditionally vs Not Among Patients With Heart Failure
The current study proposes to investigate if the provision of healthy food can improve outcomes following discharge after HF hospitalization.
- Trial name
- FOOD-HF (NCT06115369)
- Testing
- Medically Tailored Meals Delivered Conditionally, Medically Tailored Meals Delivered Unconditionally, Produce Boxes delivered Conditionally
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Texas Southwestern Medical Center
Non-valvular Atrial Fibrillation
Better Outcomes for Anticoagulation Treatment Through Observation of Atrial Rhythm
There is a need to determine actual compliance of direct oral anticoagulants and how to improve this to reduce risk of stroke in patients with atrial fibrillation.
- Trial name
- BOAT OAR (NCT03515083)
- Testing
- Alive Cor Kardia mobile electrocardiogram monitor
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Saint Luke's Health System
Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease
Assessment of Six-minute Walking Distance 6MWD Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH
To study the effect of relocation from high altitude (Quito: 2850m) to sea level on six-minute walking distance and scores in patients with pulmonary arterial hypertension PAH, who live permanently >2600m.
- Conditions
- Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease, Six-minute Walk Test, High Altitude Effects
- Trial name
- NCT07804472
- Testing
- Descent from 2850m to sea level
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Silvia Ulrich Somaini
Diabetes Mellitus, Type 2
Thiazolidinedione Intervention With Vitamin D Evaluation
This study will answer two separate questions. The first question is to test the cardiovascular effects of long-term treatment with rosiglitazone or pioglitazone when used as part of standard of care compared to similar standard…
- Trial name
- TIDE (NCT00879970)
- Testing
- pioglitazone, rosiglitazone, Vitamin D
- Where
- 331 sites in United States, Argentina and 23 more
- Volunteers
- 1,332 people
- Sponsor
- GlaxoSmithKline
Congenital Heart Disease, Hypoplastic Left Heart Syndrome
Genetic Determinants of Congenital Heart Disease Outcomes
The purpose of this study is to examine the role of genetic variation in the oxidative stress response on critical perioperative and short-term outcomes after neonatal heart surgery.
- Conditions
- Congenital Heart Disease, Hypoplastic Left Heart Syndrome, Hypoplastic Right Heart Syndrome, d-Transposition of the Great Arteries
- Trial name
- GECHO (NCT01656941)
- Where
- 5 sites in United States, Australia
- Volunteers
- 250 people
- Sponsor
- University of Michigan
Abdominal Aortic Aneurysms, Common Iliac Aneurysms
Iliac Branch Excluder ReGistry (IceBERG)
This post market registry consists of a retrospective and a prospective part. The first part is a retrospective registry of all implanted IBE devices of Gore in the Netherlands after CE mark was obtained, to get an initial…
- Conditions
- Abdominal Aortic Aneurysms, Common Iliac Aneurysms, Aneurysm
- Trial name
- IceBERG (NCT02345005)
- Testing
- The Gore® EXCLUDER® ILIAC BRANCH Endoprosthesis.
- Where
- 8 sites in Italy, Netherlands and 2 more
- Volunteers
- 100 people
- Sponsor
- Rijnstate Hospital
Type 2 Diabetes, Gestational Diabetes
Randomized Trial to Evaluate the Effectiveness of Nurse Case Management
The management of high-risk pregnancies require substantial use of medical resources. Our goal is to determine the effectiveness of a nurse case management program in which case managers are assigned to patients with high-risk…
- Conditions
- Type 2 Diabetes, Gestational Diabetes, Hypertension, Preterm Delivery
- Trial name
- NCT00295256
- Testing
- nurse case manager
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Stroke, Sleep Apnea
Impact of Early Ventilation in Stroke Outcomes in Patients With Sleep Apnea After First Ever Stroke
To evaluate the impact of early ventilation in stroke outcomes in patients with sleep apnea and first ever stroke, 1 month after stroke.
- Trial name
- NCT04903951
- Testing
- Adaptive Servoventilation (ASV) therapy, Best medical treatment
- Where
- Portugal
- Volunteers
- 90 people
- Sponsor
- Philips Portuguesa S.A.
Diabetic Retinopathy, Diabetes Mellitus, Type 2
Confronting Unequal Eye Care in Pennsylvania
Pt. 1 Diabetic retinopathy is a common eye condition among diabetic adults and can lead to severe vision impairment and even blindness.
- Conditions
- Diabetic Retinopathy, Diabetes Mellitus, Type 2, Glaucoma
- Trial name
- NCT01179555
- Testing
- Behavioral Activation, Supportive Therapy
- Where
- 3 sites in United States
- Volunteers
- 206 people
- Sponsor
- Wills Eye
Chronic Threatening Limb Ischemia
Oucomes of Endovascular Atherectomy in Femoropopliteal Arterial Disease
Peripheral artery disease (PAD) affects >200 millionadults worldwide and is amajor cause of morbidity ranging from exertional lower extremity pain to ischemic rest pain and ulcer formation.
- Trial name
- NCT07239089
- Testing
- Endovascular Atherectomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Diabetes Mellitus
Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus
Albiglutide is an analogue of glucagon-like peptide-1 (GLP-1), used to treat type 2 diabetes This study will test whether albiglutide affects the occurrence of major cardiovascular events such as heart attacks or strokes and…
- Trial name
- NCT02465515
- Testing
- Albiglutide 30 mg, Albiglutide 50 mg
- Where
- 607 sites in United States, Argentina and 26 more
- Volunteers
- 9,463 people
- Sponsor
- GlaxoSmithKline
Atrial Fibrillation, Venous Thromboembolism
NOACs Use in AF or VTE (SUNSHINE Registry)
The outcomes regiStry for non-vitamin k antagonist oral anticoagUlants treatmeNt in variouS tHrombotIc dIseases for better cliNical practicE (SUNSHINE) is a multicenter, prospective, observational non-interventional…
- Conditions
- Atrial Fibrillation, Venous Thromboembolism, Oral Anticoagulant
- Trial name
- NCT05378308
- Testing
- Patients with Atrial Fibrillation (AF) or venous thromboembolism (VTE)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Henan Provincial People's Hospital
Atherosclerosis, Coronary Artery Disease
PLATINUM Diversity
To compile acute procedural performance and clinical outcomes data for the Promus PREMIER everolimus-eluting coronary stent system in understudied/underserved patient populations including women and minorities.
- Trial name
- NCT02240810
- Testing
- Percutaneous coronary intervention (Promus PREMIER)
- Where
- 52 sites in United States
- Volunteers
- 1,501 people
- Sponsor
- Boston Scientific Corporation
Aortic Stenosis
18-F Sodium Fluoride (18F-NaF) PET for the Assessment of Bioprosthetic Aortic Valve Durability and Outcomes
This is a pilot study in which we will aim to demonstrate successful execution of the imaging protocol and to make observations regarding the calcification activity as measured by 18F-NaF PET/CT and any correlation to 1) valve…
- Trial name
- NCT03095313
- Testing
- 18F-NaF
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
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