Clinical trials: Cardiovascular Risk Management
Coronary Artery Disease
Risk-guided Disease managEment Plan to prevEnt CAD in Patients Treated With Previous Cancer
REDEEM-CAD is a prospective multi-centre study of CAD risk evaluation and management in cancer survivors 40-70 years with chemotherapy or radiotherapy >5 years ago.
- Trial name
- REDEEM-CAD (NCT05366153)
- Testing
- Coronary CT
- Where
- 2 sites in Australia
- Volunteers
- 748 people, healthy volunteers welcome
- Sponsor
- Baker Heart and Diabetes Institute
Rheumatoid Arthritis, Cardiovascular Diseases
Cardiovascular Risk Assessment for Patients With Rheumatoid Arthritis Arthritis:
One of the greatest success stories in rheumatology - the achievement of rheumatoid arthritis (RA) remission - is tempered by the fact that individuals with RA are dramatically under evaluated and under treated to reduce the risk…
- Conditions
- Rheumatoid Arthritis, Cardiovascular Diseases, Hyperlipidemias
- Trial name
- CARE RA (NCT04488497)
- Testing
- Cardiovascular Risk Assessment for Patients with Rheumatoid Arthritis, Standard of care
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Cardiovascular Risk Reduction of Having a Coronary Event
A Novel Approach to Cardiovascular Health by Optimizing Risk Management (ANCHOR)
Study Purpose and Design The goal of this study is to improve CVD risk in a primary care adult population, with the following primary objectives 1.
- Trial name
- ANCHOR (NCT01620996)
- Testing
- Minimal Intervention, Motivational Interviewing, Motivational Enhancement
- Where
- Canada
- Volunteers
- 1,708 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Cerebrovascular Accident, Stroke
Screening and Management of High-risk Populations of Stroke in Dehui City
This epidemiological survey is to analyze the prevalence rate of stroke and exposure rate of risk factors in sampling population aged 40 years and over (born before December 31,1975) in Dehui City, to provide scientific basis for…
- Conditions
- Cerebrovascular Accident, Stroke, Hypertension, Diabetes Mellitus
- Trial name
- SAMHPSDC (NCT05039034)
- Testing
- Advice according to primary prevention guidelines on stroke of China
- Where
- China
- Volunteers
- 4,100 people, healthy volunteers welcome
- Sponsor
- Yi Yang
Hypertension, Gastrointestinal Microbiome
Effect of Prebiotics on Blood Pressure Management
This survey is designed to investigate the effect of highland barley β-glucan supplementation on the regulatory of blood pressure, gut microbiota and cardiovascular risk fators in subjects with hypertention.
- Trial name
- NCT05364736
- Testing
- Highland barley β-glucan dietary supplement
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Cardiac Transplant Failure, Cardiac Transplant Rejection
Outcomes AlloMap Registry: the Long-term Management and Outcomes of Heart Transplant Recipients With AlloMap Testing
The objective of this registry is to observe short and long term clinical outcomes in heart transplant recipients who receive regular AlloMap testing as part of allograft rejection surveillance.
- Conditions
- Cardiac Transplant Failure, Cardiac Transplant Rejection, Heart Diseases
- Trial name
- OAR (NCT01833195)
- Where
- 36 sites in United States
- Volunteers
- 2,444 people, healthy volunteers welcome
- Sponsor
- CareDx
Obesity, Cardiovascular Disease
The WORLD (Weight Optimization: Revamping Lifestyles Using the Dietary Guidelines) Study - Developing, Implementing, and Testing an Education Program
The WORLD study is a single-center, year-long randomized controlled trial in free-living women. Participants were randomly assigned to follow either a lower-fat (LF) diet or a moderate-fat (MF) diet for weight management in a…
- Trial name
- WORLD (NCT00847574)
- Testing
- Moderate-fat, Lower-fat
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Penn State University
Atrial Fibrillation, Obesity and Obesity-related Medical Conditions
Metabolic Surgery for Atrial Fibrillation Elimination
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. It is estimated that between 3 and 6 million Americans are currently living with AF, while 12 million people in the United States will have AF in 2030.
- Trial name
- METSAFE (NCT07027969)
- Testing
- Roux-en-Y Gastric Bypass or Sleeve Gastrectomy, Anti-Obesity Medication (AOM) treatment
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ali Aminian
Venous Thromboembolism, Risk Assessment
Multiple Algorithms System Of All Scores in Embolism (MOSE)
The aim of this study is to overcome the current limits of the scoring systems used to predict both the thrombotic (VTE) and hemorrhagic (BLD) risk for the patient.
- Conditions
- Venous Thromboembolism, Risk Assessment, Risk Management
- Trial name
- MOSE (NCT02911012)
- Where
- 2 sites in Italy
- Volunteers
- 15,208 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Thrombosis, Cardiovascular Diseases
Efficacy and Safety of Natto Extract
Nattokinase is a potent fibrinolytic enzyme extracted from Natto. The objective of this study was to compare the efficacy of the natto extract taken by healthy volunteers, dialysis patients, and patients with cardiovascularrisk…
- Trial name
- NCT00447434
- Testing
- Natto extract (Nattokinase)
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Changhua Christian Hospital
Cardiovascular Risk Factors, Cardiovascular Diseases
Management of Cardiovascular Risk Factors
This practical experience should report a retrospective collection of data regarding cardiovascular risk factors of cardiovascular diseases.
- Trial name
- NCT00848380
- Where
- 36 sites in Switzerland
- Volunteers
- 1,492 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Cardiovascular Diseases, Vesicle
Kinetics of cEVs Over the 24-hour Dosing Interval After Low-dose Aspirin Administration
Extracellular vesicles (EVs) are small vesicles deriving from all cell types during cell activation, involved in transcellular communication, and regarded as predictors of vascular damage and of cardiovascular events.
- Trial name
- NCT05584943
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Stroke, Ischemic
Cognitive Strategies for Optimizing Brain Health And Managing Transgenerational Vascular Risk Factors Post-Stroke
People living with the cognitive effects of stroke are at risk for recurrent stroke and further cognitive decline. Also problematic is that stroke risk clusters in families and biological family members of people who have…
- Trial name
- CHAMPS-TR (NCT06479174)
- Testing
- CHAMPS-TR
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Coronary Artery Disease, Diabetes Mellitus
Exercise Testing to Screen for Unknown Coronary Artery Disease in Diabetic Patients: Does it Contribute to a Risk Reduction in Very High Risk Patients?
In the present study a cohort of diabetic patients without any symptoms and without known coronary artery disease (CAD) will be screened at the investigators' diabetes outpatients services.
- Trial name
- DADDY-D (NCT00547872)
- Testing
- exercise testing - coronary angiography - revascularization
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- TURRINI FABRIZIO
Cardiovascular Risk Factors
Echocardiography Management for Patients Requiring Care for Non-Cardiac Surgery
The growing population of institution patients with heart failure combined with the increasing number of surgical procedures performed each year supports the need for a critical analysis of how to most appropriately manage these…
- Trial name
- EGHEM (NCT01050361)
- Testing
- Transthoracic Echocardiogram (TTE)/Transesophageal Echocardiogram (TEE)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Cardiovascular Diseases, Hypertension
ICA-CHAMP: Indo-Central Asian Cardiovascular Health Assessment and Management Program
Research has shown that the presence of heart disease and stroke is higher in the Indo-Asian population compared to other ethno-cultural groups.
- Conditions
- Cardiovascular Diseases, Hypertension, Hyperlipidemia
- Trial name
- ICA-CHAMP (NCT00627159)
- Testing
- High risk assessment, Low to moderate risk
- Where
- 2 sites in Canada
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Hypertension, Cost Effectiveness
Cost-effectiveness of RAMP-HT for Patients With Uncontrolled Hypertension in Hong Kong
Hypertension (HT) is an important risk factor for stroke, coronary heart disease (CHD), heart failure and renal diseases, and the leading risk factor of global disease burden.
- Trial name
- NCT03301194
- Testing
- RAMP-HT
- Where
- Hong Kong
- Volunteers
- 158,322 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Childhood Obesity
Role of Carbohydrate Modification in Weight Management Among Obese Children
The purpose of this study is to test the hypothesis that a low-carbohydrate diet and a low-glycemic load diet will improve body mass index and result in more body fat loss than a control diet among overweight children ages 7 to…
- Trial name
- NCT00215111
- Testing
- Low carbohydrate, reduced glycemic load, and a control diet
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Myocarditis, Ventricular Arrhythmia
Role of Endomyocardial Biopsy and Aetiology-based Treatment in Pediatric Patients with Inflammatory Heart Disease in Arrhythmic and Non-arrhythmic Clinical Presentations: an Integrated Approach for the Optimal Diagnostic and Therapeutic Management (MYOPED)
Myocarditis is a complex inflammatory disease, usually occurring secondary to viral infections, autoimmune processes or toxic agents.
- Conditions
- Myocarditis, Ventricular Arrhythmia, Inflammatory Cardiomyopathy, Genetic Predisposition
- Trial name
- MYOPED (NCT06591260)
- Testing
- support treatment, cardiac medical treatment, aetiology-specific treatment, device implant, arrhythmia ablation
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Scientific Institute San Raffaele
Myocardial Infarction Postoperative, Myocardial Injury
Preoperative BNP: Epidemiological Patterns, Management Strategies and Cost Analysis of Care
Recently, the use of preoperative BNP as a preoperative risk stratifcation tool was added to the Canadian Cardiovascular Society (CCS) guidelines (4) on perioperative cardiac risk assessment and management for patients who…
- Conditions
- Myocardial Infarction Postoperative, Myocardial Injury, Death, Cardiac
- Trial name
- NCT04077294
- Testing
- Cardiac risk stratification using preoperative BNP measurement, followed by postoperative cardiac monitoring, Use of traditional perioperative cardiac risk stratification only
- Where
- Canada
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- University of Alberta