Clinical trials: Cardiovascular Risk Reduction
Decreased Cardovascular Risk, Decreased Risk of Diabetes Mellitus Type II
MoKaRi II Intervention Study
The proposed intervention study addresses the development and validation of nutritional concepts based on menu plans for patients with hypertriglyceridemia (triglycerides > 1.5 mmol/l) and participants with impaired glucose…
- Trial name
- MoKaRi II (NCT05382533)
- Testing
- Menu plans
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Jena
CVD Risk, Physical Activity
The Effect of Physical Activity on Decreasing Risk Level
Objective: The aim of the first part of this study with two stages is to determine prevalence of CVD risk and the associated variables in individuals aged 40-65 years registered in a Family Health Center (FHC) in city center of…
- Conditions
- CVD Risk, Physical Activity, Nurse's Role, Risk Reduction
- Trial name
- NCT03501017
- Testing
- physical activity program, Routine Practice
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Cardiovascular Disease Risk Factors
Reducing CVD Risk in African Americans Faith Communities
The ultimate goal of our partnership with local African-American churches is to implement an effective, multi-component intervention to increase awareness of the critical importance of healthy lifestyle in the prevention of…
- Trial name
- FAITH! (NCT02235896)
- Testing
- Education/Behavior Modification
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pre-diabetes, Pre-hypertension
Primary Prevention of Cardiovascular Disease (CVD) in Pre-diabetic & Pre-hypertensive Subjects
The purpose of this study is to determine whether treating pre-diabetic \& pre-hypertensive individuals using multiple drugs intervention (anti-hypertensive drugs (i.e., ACEI) plus anti-glycemic drug (i.e., metformin) plus…
- Trial name
- PPCVD (NCT01364675)
- Testing
- Metformin+Enalapril+Simvastatin
- Where
- Thailand
- Volunteers
- 8,900 people, healthy volunteers welcome
- Sponsor
- Ramathibodi Hospital
Cardiovascular Diseases, Metabolic Syndrome
Feasibility of Reducing Cardiovascular Disease Risk Factors in Hispanics Through a Family-Based Community Intervention
The purpose of this study is to evaluate the feasibility of a 6-month family-based community intervention to mitigate cardiovascular disease risk factors in Hispanic families in northern Colorado as measured through biometric…
- Trial name
- NCT05322876
- Testing
- Healthy Hearts Family Program
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Poudre Valley Health System
Cardiovascular Disease, Psychological Stress
Mindful Hearts Study: Mindfulness to Reduce Stress
The purpose of this study is to determine how a stress reduction program, called Mindfulness Based Stress Reduction (MBSR), compared to a health education program, improves well being and reduces the risk of heart disease in…
- Conditions
- Cardiovascular Disease, Psychological Stress, Stroke, Coronary Artery Disease
- Trial name
- NCT01784796
- Testing
- Mindfulness Based Stress Reduction, Health Education Program
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cardiovascular Diseases
Novel Strategies for Reducing Heart Disease Risk Disparities
This Western Pennsylvania-based study will (1) improve cardiovascular risk stratification to identify high-risk populations, (2) identify differences in cardiovascular risk, (3) evaluate mechanisms for population differences in…
- Trial name
- HeartSCORE (NCT00143923)
- Testing
- Nutrition, Exercise, Stress Management Counseling, usual care
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Diet Modification, Substance Use Disorders
The Impact of a Parenting Intervention on Latino Youth Health Behaviors
The purpose of this study is to test if a parenting program can be used to prevent substance use among Latino youth and at the same time promote healthy eating.
- Conditions
- Diet Modification, Substance Use Disorders, Diabetes Mellitus Risk, Cardiovascular Risk Factor
- Trial name
- FPNG+ (NCT03517111)
- Testing
- Nutrition/substance use prevention, Substance use prevention only, Academic success program
- Where
- United States
- Volunteers
- 844 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Mental Illness Persistent, Cardiovascular Prevention
Cardiac Rehabilitation for Cardiovascular Risk Reduction in People With Severe and Persistent Mental Illness
The goal of this prospective, randomized trial is to explore the link between cardiovascular disease and mortality in individuals with severe and persistent mental illness (SPMI).
- Trial name
- NCT05659498
- Testing
- Cardiac Rehabilitation Program
- Where
- Canada
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Lady Davis Institute
Obesity
Diet Tracking Prescriptions for Weight Loss
Lifestyle interventions are effective at producing modest weight loss. One of the strongest predictors of weight loss is food tracking, which involves logging all food and beverage consumed each day in an effort to stay within a…
- Trial name
- NCT06311175
- Testing
- Dietary Tracking Prescription
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Cardiovascular Diseases
Evaluating the Effect of Neighborhood Environments on Cardiovascular Risk Factors
Cardiovascular disease (CVD) is one of the main causes of death in the United States. Research has shown that individuals who maintain an active lifestyle are less likely to develop CVD.
- Trial name
- NCT00361673
- Where
- 2 sites in United States
- Volunteers
- 1,140 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Aging
CALERIE: Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy
The purpose of this study is to test the hypothesis that two years of sustained 25% caloric restriction (CR) in men age 21-50 (inclusive) and women age 21-47 (inclusive) will slow aging and protect against age-related disease…
- Trial name
- NCT00427193
- Testing
- Caloric Restriction (CR), Control
- Where
- 3 sites in United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Duke University
Life Style, Healthy, Life Style
A Randomized-Controlled Lifestyle Intervention to Increase Physical Activity Levels in Adolescents
Students at the age of 14-16 years will be randomized to one intervention arm or one control arm in a 1:1 ratio. Participants of both groups receive a fitness tracker to count the amount of their steps taken.
- Trial name
- healthy tyrol (NCT04749004)
- Testing
- Promotion of physical activity
- Where
- Austria
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Diabetes Mellitus, Cardiovascular Diseases
Feasibility of a Youth-led NCD Risk Reduction Initiative in Selected Schools of Slums in Karachi, Pakistan: a Mixed-methods, pre-and Post-intervention Study
The study will occur in ten selected schools within Azam Basti and Mehmoodabad, organized into five sequential phases. Phase I involves identifying NCD modifiable risk factors among younger peers (Classes 5 and 6 students) using…
- Conditions
- Diabetes Mellitus, Cardiovascular Diseases, Cancer, Lung Diseases
- Trial name
- NCT06465771
- Testing
- Youth-led NCD risk reduction intervention
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Cardiovascular Morbidity, Risk Reduction
Help Everyone Assess Risk Today: LEnten Nutrition Study (HEART-LENS)
The purpose of this study is to evaluate the impact of community health screening, health education and nutritional intervention on risk factors for cardiovascular disease in a predominantly African American population.
- Conditions
- Cardiovascular Morbidity, Risk Reduction, Nutrition Disorders
- Trial name
- NCT05057650
- Testing
- Vegan diet
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Cardiovascular Diseases
HCP-facing Portfolio Diet Toolkit Validation Study
There is limited support in primary care for diet and lifestyle, the cornerstones for therapy in clinical practice guidelines. Canadian dietitian services are not covered by provincial health plans and most physicians cite a lack…
- Trial name
- NCT05915455
- Testing
- HCP-facing Portfolio Diet Infographic + Informative Video, Portfolio Diet Application
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Nicotine Dependence, Tobacco Toxicity
Cigarette Harm Reduction With Electronic Cigarette Use
This is an observational, crossover study that will be examine use behaviors, chemical exposures, and biological effects of SREC compared to TC use in subjects confined to a research ward setting.
- Conditions
- Nicotine Dependence, Tobacco Toxicity, Nicotine Dependence, Cigarettes, Cardiovascular Risk Factor
- Trial name
- NIDA-SREC (NCT03473483)
- Testing
- SREC
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Insulin Resistance, Hypertriglyceridemia
Comparing Tricor, Avandia, or Weight Loss to Lower Cardiovascular Risk Factors in People With High Triglycerides.
Approximately 1/4 of the US population has insulin resistance and the associated risk factors such as elevated lipid levels -triglycerides (type of fat from what we eat and what the liver produces and low HDL cholesterol which is…
- Trial name
- NCT00186537
- Testing
- Rosiglitazone, Fenofibrate, Weight Loss
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Stanford University
All-cause Mortality, Cardiovascular Disease
The Global Cardiovascular Risk Consortium
The Global Cardiovascular Risk Consortium (GCVRC) brings together harmonized individual-level data from currently more than 2 million (anticipated: approximately 3 million) individuals across 133 cohorts, 40 countries, and 6…
- Trial name
- NCT05466825
- Where
- Germany
- Volunteers
- 3,000,000 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Metabolic Syndrome, Physical Activity
Medical and Physiological Benefits of Reduced Sitting
The most important objective of this randomized controlled trial in subjects with increased cardiovascular and metabolic risk factors is to investigate whether only reduced daily sitting improves human cardiovascular and…
- Conditions
- Metabolic Syndrome, Physical Activity, Insulin Resistance, Cardiovascular Diseases
- Trial name
- NCT03101228
- Testing
- Reduced sitting
- Where
- Finland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital