Clinical trials: Care
Intractable Pain, Palliative Care
Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-induced Bone Pain
Background: Cancer-induced bone pain (CIBP) is common in people with cancer. Bone cancer can also lead to anxiety, depression, and reduced mobility and quality of life.
- Trial name
- NCT02522611
- Testing
- Resiniferatoxin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Overweight and Obesity, Pregnancy Complications
Healthy for my Baby- RCT of a Lifestyle Intervention for Overweight Women in Preconception
The purpose of this study is to determine whether an intervention combining motivational interviewing and follow-up with a mobile phone application will help overweight women and their partners adopt healthy lifestyle habits in…
- Conditions
- Overweight and Obesity, Pregnancy Complications, Health Behavior, Life Style
- Trial name
- NCT04242069
- Testing
- Healthy for my Baby, Usual Care
- Where
- 2 sites in Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Perioperative Care, Intermittent Fasting
Intermittent Fasting Versus Carbohydrate Drinks Before Surgery
The purpose of this study is to investigate whether time-restricted feeding, a form of intermittent fasting, before surgery improves insulin resistance around the time of surgery, compared to carbohydrate drinks and standard…
- Conditions
- Perioperative Care, Intermittent Fasting, Carbohydrate Loading, Preoperative Fasting
- Trial name
- PRINCESS (NCT05760339)
- Testing
- Time-restricted feeding, Carbohydrate loading
- Where
- Netherlands
- Volunteers
- 75 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Prevention Harmful Effects, Health Maintenance
Lifewise Preventive Video Education in Primary Care
It is widely accepted that prevention is far more impactful than curative medicine and must be included in primary care. In a previous pilot study, we evaluated passive video preventive lifestyle education in the emergency…
- Conditions
- Prevention Harmful Effects, Health Maintenance, Preventive Health Care, Dietary Habits
- Trial name
- NCT06730737
- Testing
- Video preventive education
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Trinity Health-Livonia
Delirium, Anxiety
Patient- and Family-centred Care in the Adult Intensive Care Unit: a Feasibility Study
Background: In the intensive care unit (ICU), delirium in patients and long-term mental health challenges in both patients and their family members are highly prevalent.
- Conditions
- Delirium, Anxiety, Post Intensive Care Unit Syndrome, Post Intensive Care Unit Syndrome Family
- Trial name
- FAM-ICU (NCT06974214)
- Testing
- FAM-ICU
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
HPV Vaccination, Uptake Vaccination
PREVENT HPV -Related Cancers Trial
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Uptake Vaccination, Series Completion
- Trial name
- NCT07217145
- Testing
- PREVENT
- Where
- United States
- Volunteers
- 1,455 people, healthy volunteers welcome
- Sponsor
- University of Utah
Written Exposure Therapy, Breathing Techniques
Early Intervention for Postpartum PTSD: Comparing Written Exposure and Capnometry-Guided Breathing Therapy
The purpose of this study is to examine two early interventions, Written Exposure Therapy and Capnometry Guided Breathing, to reduce post-traumatic stress disorder (PTSD) symptoms in women after childbirth as compared to usual…
- Conditions
- Written Exposure Therapy, Breathing Techniques, PTSD (Childbirth-Related), Postpartum Care
- Trial name
- NCT07342530
- Testing
- Written Exposure Therapy (WET), Capnometry-Guided Breathing Intervention (CGRI)
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Stanford University
Lower Extremity Surgery, Patient Education
Effect of Teach-Back-Based Discharge Education in Lower Extremity Surgery Patients
This study aims to determine the effect of discharge education based on the Teach-Back method on patients' learning needs and readiness for hospital discharge following lower extremity surgery.
- Conditions
- Lower Extremity Surgery, Patient Education, Postoperative Care
- Trial name
- NCT07558070
- Testing
- Teach-Back Education, Routine Discharge Education
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Patient Satisfaction, Cancer
Patient Satisfaction Following Multidisciplinary Cancer Care Assessment in Day Hospital.
This study aims to evaluate patient satisfaction following a multidisciplinary "complex assessment" conducted in a Day Hospital setting at the Centre Hospitalier de Martigues.
- Conditions
- Patient Satisfaction, Cancer, Quality of Health Care
- Trial name
- EVAQSAP-HDJ-BC (NCT07560423)
- Testing
- Multidisciplinary Complex Assessment
- Where
- France
- Volunteers
- 309 people
- Sponsor
- Centre Hospitalier de Martigues
Death, Spiritual Care
Curriculum Design and Effectiveness in Death and Spiritual Care
This study will be conducted using a randomized experimental design with a pre-test/post-test control group to determine the effectiveness of a curriculum on "Death and Spiritual Care in the Elderly"-developed for students in the…
- Conditions
- Death, Spiritual Care, Spiritual Care Education
- Trial name
- NCT07902531
- Testing
- Death and Spiritual Care Education, Control
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Neonatal Palliative Care, Educational Intervention for NICU Nursing Performance
Effect of an Educational Program on Neonatal Intensive Care Nurses' Performance Regarding Neonatal Palliative Care in Egypt.
This quasi-experimental study aims to evaluate the effect of an educational program on neonatal intensive care unit (NICU) nurses' performance regarding neonatal palliative care.
- Trial name
- NCT07902557
- Testing
- Neonatal Palliative Care Educational Program
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Asmaa Rashad
Neuro-Degenerative Diseases, Care Givers
Informational Needs of Caregivers of Patients With Neuromotor Disease in Rehabilitation Hospitalization: Validation Study of the QBI-R/V
Background and rationale. Although the literature suggests that caregivers have different needs at various stages of the patient's illness, to date, most studies have focused only on the needs of caregivers of patients with…
- Conditions
- Neuro-Degenerative Diseases, Care Givers, Ictus, Brain Injury
- Trial name
- NCT07903298
- Testing
- QBI questionnaires
- Where
- 13 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Palliative Care, Health Services, Palliative Care
Integrating Rhythmical Massage in Palliative Care
People receiving palliative and end-of-life care may experience pain, fatigue, sleep difficulties, anxiety, and other symptoms that affect their comfort and quality of life.
- Conditions
- Palliative Care, Health Services, Palliative Care, Massage Intervention
- Trial name
- NCT07904611
- Testing
- Rhythmic Massage
- Volunteers
- 70 people
- Sponsor
- Monash University Malaysia
Resilience, Psychological, Advance Care Planning
Facilitating Advance Care Planning Discussions for People With Advanced Cancer
The aims of this study are to (1) identify the advance care planning deliberation process among 20 dyads of patients with advanced cancer and family caregivers and (2) conduct usability testing among 9 dyads to refine the content…
- Trial name
- NCT06061965
- Testing
- Web-based resilience-building intervention
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Illinois Chicago
Position on Premature Infants, Nursing Care
The Effect of Positioning on Comfort, Stress Levels, and Physiological Functions in Premature Infants
A randomized crossover study was made to investigate the effect of different positions on the comfort, stress, and physiological functions of premature infants receiving non-invasive mechanical ventilation in the neonatal…
- Trial name
- NCT06752005
- Testing
- Intervention Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Aydin Adnan Menderes University
Sepsis - to Reduce Mortality in the Intensive Care Unit, Septic Shock
Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock
Sepsis is a dysregulated host response to infection that leads to life-threatening organ dysfunction and represents a major healthcare problem.
- Trial name
- CARBON (NCT07179276)
- Testing
- CO2gap-guided resuscitation strategy
- Where
- 29 sites in France
- Volunteers
- 750 people
- Sponsor
- University Hospital, Clermont-Ferrand
Child, Anaphylaxis
Observation Periods and Biphasic Reaction Risk Factors in Pediatric Emergency Anaphylaxis Cases
This study reviews the medical records of children who presented to the pediatric emergency department of Adnan Menderes University Hospital with a diagnosis of anaphylaxis between January 2014 and December 2024.
- Conditions
- Child, Anaphylaxis, Pediatric Emergency Care, Biphasic Anaphylactic Reaction
- Trial name
- NCT07231393
- Volunteers
- 67 people
- Sponsor
- Aydin Adnan Menderes University
Sleep Disturbance, Intensive Care Units
The Effect of Pink Noise and the Quiet Night Intervention on Sleep Parameters in Intensive Care Unit Patients: A Single-Center Randomized Controlled Trial
Sleep disruption is common in adult intensive care unit (ICU) patients and is often worsened by environmental noise and nighttime care activities. Poor sleep may negatively affect recovery and well-being.
- Trial name
- NCT07412964
- Testing
- Acoustic Noise Masking Intervention, Quiet Night Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Abant Izzet Baysal University
Ventilated Patient in Intensive Care, Failure of Extubation
The Rapid Shallow Breathing Index (RSBI) is a Widely Used Predictor for Weaning Patients From Mechanical Ventilation This Study Aims to Determine the Predictive Value of RSBI Measurements for Extubation Success in Mechanically Ventilated ICU Patients
Early extubation in ICU patients is crucial for reducing complications of prolonged ventilation, including morbidity and mortality.
- Trial name
- NCT07467265
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Prenatal Care, Midwifery Education
Peyton Model In Midwifery Prenatal Education
In this study, conducted with 68 students from the Gülhane Midwifery Department, the impact of the Peyton model on prenatal examination training was investigated.
- Conditions
- Prenatal Care, Midwifery Education, Clinical Self-Efficacy, Anxiety
- Trial name
- NCT07530822
- Testing
- Peyton Model Training, Standard Training
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi