Clinical trials: Care
Sickle Cell Disease
Development and Evaluation of an Information Management System and Communication System for Population-wide Point-of-care Infant Sickle Cell Disease Screening
Although over 75% of children with sickle cell disease (SCD) are born in sub-Sahara where the disease highly contributes to under-5 mortality and causes life-long debilitation, evidence-based strategies to control SCD are not…
- Trial name
- SIMCS SCD (NCT06563440)
- Testing
- Digital app and information system
- Where
- 2 sites in United States, Uganda
- Volunteers
- 24,000 people, healthy volunteers welcome
- Sponsor
- Makerere University
Hand Hygiene, Health Education
Effect of Virtual Reality-Based Handwashing Education on Knowledge, Skills, and Emotional Indicators in Preschool Children
A randomized controlled trial designed to evaluate the effects of virtual reality-based handwashing education on handwashing knowledge, skills, and emotional indicators in preschool children aged 5-6 years.
- Conditions
- Hand Hygiene, Health Education, Infection Prevention
- Trial name
- VR-HAND (NCT07518082)
- Testing
- Virtual Reality-Based Handwashing Education, Traditional Handwashing Education
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Hair and Scalp Health
The Impact of African American Women's Hair Care Practices and Hair Attitudes on Exercise Habits
The purpose of this research study is to better understand African American women's hair and hair styling practices and how these practices affect attitudes and viewpoints regarding exercise.
- Trial name
- NCT00691782
- Testing
- Survey of exercise practices
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
SARS-CoV Infection, Interferon
The Containing Coronavirus Disease 19 (COVID-19) Trial
In recent months severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) has emerged as a novel human pathogen and, susceptibility amongst humans is presumed to be universal.
- Conditions
- SARS-CoV Infection, Interferon, Covid19
- Trial name
- ConCorD-19 (NCT04552379)
- Testing
- Peginterferon beta-1a
- Where
- Chile
- Volunteers
- 1,173 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Mental Disorder, Perinatal
Perinatal Mental Health Care in Switzerland
This qualitative study with quantitative elements examines the health care provided to women who suffered from mental disorder during pregnancy and / or in the first year after birth (i.e. during the perinatal phase).
- Conditions
- Mental Disorder, Perinatal, Depression, Anxiety Disorders
- Trial name
- MADRE (NCT04185896)
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Post-menopausal Osteoporosis
Bisphosphonate Action on the Appendicular Skeleton: Evidence for Differential Effects
A study to determine if the three licensed bisphosphonates (alendronate, ibandronate and risedronate):a) affect the peripheral skeleton differently, as assessed by quantitative ultrasound of bone (QUS), peripheral quantitative…
- Trial name
- NCT00666627
- Testing
- Ibandronate, Risedronate, Alendronate
- Where
- United Kingdom
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Dental Education and Special Care Dentistry
Comparison of Game-Based Learning and Model Arm Practice for Teaching Intravenous Cannulation to Dental Students
This randomized controlled study aimed to compare the effectiveness of game-based learning (GBL) and model arm practice in teaching peripheral intravenous cannulation (PIVC) skills to final-year dental students.
- Trial name
- NCT07060924
- Testing
- Game-Based Learning (GBL), Model Arm Practice
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara University
Cesarean Section
The Effect of Abdominal Binder Use on Postpartum Pain, Bleeding, and Breastfeeding Success in Cesarean Delivery Women
The aim of this randomized controlled interventional study is to identify the effect of the use of an abdominal binder on postpartum pain, bleeding, and breastfeeding success in primiparous women who have undergone planned…
- Trial name
- NCT04965779
- Testing
- Abdominal Binder, Postpartum nursing care
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Covid19
Seroprevalence of IgG Antibodies to SARS-CoV-2 (COVID-19) in Primary Health Care Workers and Their Household Contacts
Many uncertainties remain regarding the epidemiological and clinical characteristics of COVID-19, including the number of people exposed to the disease, the persistence of the humoral response and its associated neutralisation…
- Trial name
- COVID-SeroPRIM (NCT04808986)
- Testing
- Serological test for the detection of IgG anti-SARS-CoV-2
- Where
- France
- Volunteers
- 2,817 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Pulmonary Hemorrhage
Lung Ultrasound Safety in Humans
The purpose of this study is to investigate if diagnostic ultrasound as it is routinely performed in humans causes lung hemorrhage significant enough to appear on thoracic CT.
- Trial name
- NCT02453724
- Testing
- Observation for safety
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Polyneuropathies, Septic Shock
Electrical Muscle Stimulation in the Development of Acquired Weakness in Patients With Severe Sepsis and Septic Shock
The aim of this study is to compare the effect of EMS and conventional physical therapy on strength and muscle mass and development in adult patients with severe sepsis and septic shock.
- Conditions
- Polyneuropathies, Septic Shock, Muscle Weakness
- Trial name
- NCT03765489
- Testing
- electrical muscle stimulation, conventional physical therapy
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Chile
Substance-Related Disorders, Alcohol-Related Disorders
Conflict Between Maternal Autonomy and Child Health in Substance-use
Qualitative project, comprising open-ended semi-structured interviews with healthcare workers, who provide antenatal care to substance-using women.
- Conditions
- Substance-Related Disorders, Alcohol-Related Disorders, Amphetamine-Related Disorders, Inhalant Abuse
- Trial name
- NCT02797990
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Transitional Care, Frail Elderly
Making Health Care Safer for Older Adults Receiving Skilled Home Health Care Services After Hospital Discharge
Care transitions are the movement of a person from one healthcare setting to another. Older adults who require skilled home health care ("home health") services (e.g., home-based nursing) after hospital discharge are at high risk…
- Conditions
- Transitional Care, Frail Elderly, Home Health Care
- Trial name
- NCT05182060
- Testing
- Transition Intervention
- Where
- United States
- Volunteers
- 761 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hepatitis C, Drug Users
The Impact on Linkage-to-care of an Alternative Hepatitis C Screening Method in PWID
Screening, diagnosis and treatment of HCV in PWID, should be part of a harm reduction strategy. Treatment of HCV infected PWID should be delivered in a multidisciplinary care setting with services to reduce the risk of…
- Conditions
- Hepatitis C, Drug Users, Harm Reduction, HIV
- Trial name
- NCT02971488
- Testing
- Screening for HCV in PWID and Linkage-To-Care
- Volunteers
- 529 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Infanta Leonor
End of Life Process
Can We Improve the Quality of Care at the End of Life in Israel?
The purpose of this study is to determine whether end-of-life training of ICU professionals leads to improvements in ICU care process, teamwork and family satisfaction.
- Trial name
- ISRAEOLC (NCT02129283)
- Testing
- Simulation training
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Adolescent Substance Use
Guiding Good Choices for Health
This study evaluates the feasibility and effectiveness of implementing Guiding Good Choices (GGC), an anticipatory guidance curriculum for parents of early adolescents, in three large, integrated healthcare systems.
- Trial name
- GGC4H (NCT04040153)
- Testing
- Guiding Good Choices
- Where
- 3 sites in United States
- Volunteers
- 3,636 people, healthy volunteers welcome
- Sponsor
- University of Washington
Primary Prevention
Adolescents as Change Agents in the Incorporation of a Parental Component for a School Based Prevention Program
Cluster-Randomized Clinical trial, which includes the development and activation of an intervention program among young adolescents and their parents.
- Trial name
- NCT04688619
- Testing
- Prevention Program "young In Favor of Myself", active parents, Prevention Program "young In Favor of Myself", no parental involvement
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
Aging
What Older Adults and Their Caregivers Need for Making Better Decisions at Home
Most Canadians wish to stay at home in their old age. As older adults stay at home with the support of home and community services, they are often faced with difficult decisions, such as "Who will look after me when I can't look…
- Trial name
- NCT04327830
- Testing
- Decisional needs assessment
- Where
- Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Medical Scribes
Evaluation of the Use of Medical Scribes in VAMC Emergency Departments and Specialty Care Clinics
Background and study aims: Medical scribes are trained paraprofessionals that assist providers with documenting patient encounters.
- Trial name
- NCT04154462
- Testing
- Scribes
- Where
- 12 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- VA Boston Healthcare System
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