Clinical trials: Caries, Dental
Tooth Decay
Comparing the Clinical Success of Two Different CAD/CAM Full Cuspal Coverage Onlays
This is a single-center, ten-year, randomized controlled, split-mouth clinical trial. A total of 164 adult patients requiring full-cuspal coverage onlays will be enrolled.
- Trial name
- CUSTOM (NCT07519382)
- Testing
- full cuspal covarage onlay
- Where
- Hungary
- Volunteers
- 164 people
- Sponsor
- Semmelweis University
pH
The Impact of Anti- Asthmatic Medications on Salivary pH and Dental Caries Pattern in a Group of Egyptian Children With Bronchial Asthma
The impact of Anti- Asthmatic medications on salivary pH and dental caries pattern in a Group of Egyptian Children with Bronchial Asthma.
- Trial name
- NCT03877874
- Testing
- Aironyl syrup(Terbutaline sulfate) + Epidrone syrup(Dexamethone)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Prevention Management Model for Early Childhood Caries (MAYA Project)
The purpose of this study is to determine whether dental disease patterns and transmissable bacteria that are known to cause a severe form of dental decay in young children can be reduced or eliminated by treating mothers and…
- Trial name
- NCT00066950
- Testing
- Chlorhexidine gluconate, Fluoride Varnish
- Where
- United States
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dentin Caries
Evaluation of the Effect of Flowable Composites on Postoperative Sensitivity in Class I Restorations.
The aim of this study is to evaluate the effect of flowable conventional and bulk-fill composites on postoperative sensitivity in class I cavities over long-term follow-up.
- Trial name
- NCT07343050
- Testing
- Dental restorations
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Dental Caries
Efficacy of Three Toothpastes Using an in Situ Caries Model
This will be a single-centre, randomized, blinded, placebo-controlled, 6-treatment, 4-period crossover, incomplete block design, in situ caries study in healthy adults who wear a removable bilateral mandibular partial denture.
- Trial name
- NCT02751320
- Testing
- 0.425 % w/w phytate,1150ppm F, 0.85 % w/w phytate,1150ppm F, 0.85 % w/w phytate,0.3%ZnCl2 0.5% sodium citrate, 1150ppm F
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dental Caries
Study of Factors of Genetic Susceptibility Associated to Severe Caries Phenotype
Alteration of the post- eruptive enamel microstructure due to a mutation of a gene coding for a matrix protein could increase the susceptibility of the enamel to caries after tooth eruption.
- Trial name
- Cariogene (NCT00541060)
- Testing
- mutation
- Where
- France
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Caries
Prevalence of Dental Caries in Patients With Dental Crowding
Dental crowding causes limited access for the toothbrush, and the natural cleansing effect of the teeth by the tongue and saliva is also limited.
- Trial name
- NCT06438926
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endodontically Treated Teeth
Clini Asses of Retentn,Pt Satisfactn and Recurrent Caries of Endocrs Versus Post Crs Using Reinforced Lithium Silicate
Coronal retention of the restoration of RCT teeth is usually compromised, thus intraradicular posts combined or not with core material may be required.
- Trial name
- NCT03713918
- Testing
- Reinforced lithium silicate endocrowns, Post retained reinforced lith silicate crn
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acute Otitis Media, URTI
Xylitol for the Prevention of Acute Otitis Media Episodes in Children
This is a randomized controlled trial of regular daily use of xylitol (or "birch sugar"), a natural sweetener that has antimicrobial properties, for the prevention of acute otitis media (AOM, primary outcome) as well as upper…
- Conditions
- Acute Otitis Media, URTI, Dental Caries in Children
- Trial name
- POME-Xylitol (NCT03055091)
- Testing
- Xylitol syrup
- Where
- 2 sites in Canada
- Volunteers
- 472 people
- Sponsor
- Unity Health Toronto
Brain Diseases
Evaluation of a New MRI Technique to Reduce Breathing-Related Artifacts in Brain Imaging
This study aims to improve the quality of brain magnetic resonance imaging (MRI) scans by testing a new imaging method that reduces distortions caused by breathing.
- Trial name
- DORK (NCT07305948)
- Testing
- Dual Free Induction Decay (FID) Navigator Off-Resonance Corrected (DORK) 3D Susceptibility Weighted (SWI) Echo Planar Imaging (EPI)
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Region Stockholm
Class IV Dental Caries
Evaluate the Shade Matching of Polychromatic Versus Monochromatic Composite Layering Techniques in Fractured Class IV Maxillary Central Incisors Using Universal , Layering & One Shade Composite In-vivo on Patients
The goal of this clinical trial is to evaluate shade matching ability of different techniques of application and different materials of resin composite restorations in class IV carious lesions
- Trial name
- NCT06743984
- Testing
- Polychromatic resin composite, Monochromatic resin composite
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Badr University
Tooth Decay
Clinical and Radiographic Evaluation of Alkasite Restorative Material Versus Glass Ionomer Cement
To evaluate the clinical and radiographic performance of Alkasite restorative material versus glass ionomer in restoration of primary molars.
- Trial name
- GIC (NCT06195449)
- Testing
- ALKASITE RESTORATIVE MATERIAL, Glass Ionomer Cement
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Dental Caries
On Probiotic, Dental Caries, and Orthodontic Patients
To investigate the short term effect of probiotic oil on plaque acidogenicity among orthodontic patients. Shortage on testing the effect of probiotic on Orthodontic patients can be seen on litterateurs making a gap of whether is…
- Trial name
- NCT04593017
- Testing
- Active Probiotic
- Where
- Sweden
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Dental Caries in Children
Pharmacokinetics of Advantage Arrest in Healthy Children 13-Months to 13-Years of Age
The purpose of this study is to further characterize basic pharmacokinetic (PK) parameters in healthy children to contribute to evidence for the safety of silver diamine fluoride (SDF; Advantage Arrest).
- Trial name
- NCT05670743
- Testing
- 38% silver diamine fluoride
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Advantage Silver Dental Arrest, LLC
Dental Caries in Children
Comparison of ACTIVA BioACTIVE Versus Compomer in Restoring Dental Decay in Primary Molar Teeth
A clinical trial to evaluate a filling material (ACTIVA) and compare it to a traditional filling material (compomer) to restore decayed deciduous teeth in children
- Trial name
- NCT03516838
- Testing
- ACTIVA™ BioACTIVE, Compomer
- Where
- Belgium
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Ghent
Caries, Reversible Pulpitis
Management of Deep Carious Lesions in Adults
Dental caries is one of the most prevalent non-communicable disease. However, despite its prevalence there is no consensus on how much caries to remove prior to placing a restoration to achieve optimal outcomes.
- Trial name
- NCT05144711
- Testing
- Selective caries excavation, Non selective caries excavation
- Where
- Jordan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Health Behavior
Oral Health of Individuals Who Attended a Mother-child Dental Care Program - Longitudinal Study
The aim of this longitudinal study was to assess the oral health of individuals attending a mother-child dental care program (PPPWB).
- Trial name
- NCT01272544
- Volunteers
- 278 people
- Sponsor
- Universidade Federal do Piauí
Badly Decayed Teeth
Immediate Implant Placement in the Esthetic Zone With and Without Using Autogenous Mixed With Xenograft
Xenografts are graft materials derived from the inorganic portion of animal bones; the most common source is bovine the removal of the organic component are processed to remove their antigenicity, while the remaining inorganic…
- Trial name
- NCT04096209
- Testing
- autograft mixed with xenograft bone
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Cairo University
Dental Caries
Remineralization of Dentine Caries Using Two Remineralizing Agents Which Are Nanosilver Fluoride and Casein phosphopeptides_amorphous Calcium Phosphate
The study is randomized controlled trial ...The null hypothesis suggests that there is no significant difference between nanosilver fluoride and sodium fluoride with Casein phosphopeptides_amorphous calcium phosphate in the…
- Trial name
- NCT04930458
- Testing
- Nanosilver fluoride, Sodium fluoride with casein phosphopeptides amorphous calcium phosphate, Sodium fluoride varnish
- Where
- Iraq
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dental Caries
Clinical Comparison of Restorative Materials
Composite resin materials are the first treatment choice in direct restorations due to their good mechanical properties, excellent esthetic properties, conservative preparation, and successful clinical performance.
- Trial name
- NCT06637605
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
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