Clinical trials: Caries; Dentin
Deep Caries Lesion of Pemanent Teeth
Outcome of Selective Caries Removal Performed by Undergraduate Students
Deep tooth decay can sometimes reach very close to the nerve of a tooth. Traditionally, dentists may remove all of the decayed tooth tissue, but removing too much tissue can increase the risk of exposing or damaging the nerve.
- Trial name
- NCT07765810
- Testing
- Selective caries removal to soft dentine, Selective Caries Removal to Firm/Leathery Dentine
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Caries; Dentin, Dental Restoration Failure of Marginal Integrity
Absence of Liner Following the Selective Caries Removal (ALFSCaRe)
This randomized, multi-centric, controlled clinical trial will assess the effectiveness of a simplified restorative protocol used after the selective carious tissue removal in posterior teeth presenting deep carious lesions.
- Trial name
- (ALFSCaRe) (NCT03933176)
- Testing
- Restoration of carious lesions
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Dental Caries
Postoperative Pulpal Complications in Posterior Resin Composite Restorations Without Glass-ionomer Cement Lining
The purpose of this study is to observe the effects of glass-ionomer cement (GIC) lining on risk of pulpal complications in deep occlusal cavities with resin-based restorations.
- Trial name
- NCT01567514
- Testing
- Glass ionomer cement lining
- Where
- Thailand
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Carious Lesion
Efficacy of Nanoparticle-incorporated Bonding Agent on Post-restorative Sensitivity
Type of study: Randomized Clinical trial To compare post-restorative sensitivity between titania nanoparticle reinforced bonding agent and bonding agent without nanoparticles in posterior composite restorations.
- Trial name
- NCT05744648
- Testing
- Composite resin restoration using Titania nanoparticle reinforced bonding agent, Composite resin restoration without Titania nanoparticle incorporated bonding agent
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Dentin Bridge, Pulpitis
Partial Pulpotomy on Caries Free Human Teeth
The purpose of this study is to compare the human pulp response to partial pulpotomy using White ProRoot MTA or iRoot BP in the terms of dentinal bridge formation and inflammation.
- Trial name
- NCT01420718
- Testing
- MTA, iRoot BP
- Where
- Iran
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Caries Assessment, Caries; Dentin
Evaluation of Radiation-Free Caries Detection Integrated Into Intraoral Scanners Compared With Conventional Diagnostic Methods
The goal of this study is to evaluate if an intraoral scanning device with an integrated radiation-free caries detection tool (near-infrared light) can detect early tooth decay.
- Conditions
- Caries Assessment, Caries; Dentin, Caries; Initial
- Trial name
- NCT07342595
- Testing
- intraoral scan with integrated caries detection tool
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Albert Mehl
Caries, Dental
Management of Occlusal Dentinal Caries in Deciduous Molars
This study evaluated and compared the efficacy of no caries removal and sealing with a well-adapted and crimped stainless steel crown verses selective caries removal upto soft dentin and upto firm dentin in healing and/or…
- Trial name
- MOD (NCT03552835)
- Testing
- no caries removal, partial caries removal upto soft dentin, partial caries removal upto firm dentin
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sneha D. Suwarnkar
Dental Caries, Secondary Dental Caries
Influence of the Number of Layers of a One Bottle Adhesive on the Longevity of Composite Restorations in Primary Molars
The aim of this study is to determinate the influence of an alternative adhesive application protocol (i.e. consecutive application of an extra adhesive layer)on restoration longevity in primary molars.
- Trial name
- NCT01680289
- Testing
- Three adhesive coats, Two adhesive coats
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Reversible Pulpitis, Pulpitis
Antibacterial Effect and Clinical Performance of Chitosan Modified Glass Ionomer
The study is a randomized clinical trial that assesses the clinical success and the antibacterial effect on carious dentine of glass ionomer when modified with Chitosan and/or Titanium dioxide nano particles vs the control group…
- Conditions
- Reversible Pulpitis, Pulpitis, Caries,Dental, Caries Class I
- Trial name
- NCT04365270
- Testing
- Glass Ionomer, Chitosan Low Molecular Weight (20-200 Mpa.S), Chlorhexidine Diacetate
- Where
- Egypt
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries
Microbiological Evaluation and Clinical 24-month Follow-up of Adhesive Systems on Carious Dentin
The objectives were to evaluate the antibacterial effect of self-etching adhesives on carious dentin and the clinical results of restorations in a randomized controlled clinical trial.
- Trial name
- NCT05676671
- Testing
- Applications of self-etching adhesives and dental restorations
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Class II Dental Caries
Clinical Performance of Bulk-Fill Composite Using With Adhesives With or Without Chlorhexidine
This study aims to evaluate the clinical success of chlorhexidine-containing dentin bonding agent in primary molars with a 12-month follow-up.
- Trial name
- NCT06257108
- Testing
- Class II Cavity Restorations
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uşak University
Deep Dental Caries
Attitude and Practice for Deep Caries Management Between Egyptian and Indian Dentists : a Cross Sectional Study
Study type: Observational Study To assess and compare the attitudes, and practices of dentists in Egypt and India regarding the removal of deep dentin caries and preferred restorative strategies.
- Trial name
- NCT06806254
- Where
- Egypt
- Volunteers
- 766 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Comparative Evaluation of Effectiveness of Hall Technique and Resin Modified Glass Ionomer Cement in Controlling Occlusoproximal Caries in Primary Molars in Children
•To investigate clinical and radiographic outcomes of Hall Technique and conventional restorative care using RMGIC in occulusoproximal carious lesions of primary molars in children.
- Trial name
- NCT04355000
- Testing
- Hall technique, RMGIC restoration
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Dental Caries, Dental Pulp Exposure
Stepwise and One Step Techniques In Deep Dentin Lesion
This double blind, randomized, controlled clinical trial aimed to observe the success of stepwise (SW) and one step (OneS) excavation techniques in the management of deep dentin caries.
- Trial name
- NCT04351048
- Testing
- Stepwise Excavation, One Step Excavation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TIJEN PAMIR
Caries, Salivary Function
Lesion Progression After Icon Treatment in Young Adults
This is a three year single site clinical evaluation of a FDA approved (510(k):K100062) lesion penetrating resin used to infiltrate and hamper progression of proximal carious lesions.
- Conditions
- Caries, Salivary Function, Tooth Sensitivity
- Trial name
- NCT01988337
- Testing
- Resin infiltration, Mock treatment
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- DMG Dental Material Gesellschaft mbH
Dental Caries Extending Into Dentin
Antibacterial Effect of Light-activated Calcium Silicate Versus Light-activated Calcium Hydroxide
This is a randomized clinical study. 48 subjects with a confirmed diagnosis of deep carious molars without pulpal lesions were randomized to one of two treatments: Patients treated with Light-cured calcium silicate (Theracal)…
- Trial name
- NCT03214770
- Testing
- TheraCal, light-cured calcium hydroxide
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentin, Carious, Indirect Pulp Capping
Clinical Success of Indirect Pulp Capping: 1-Year Follow-Up
The goal of this clinical trial is to compare the clinical success of theracal pt, therabase, and biodentine indirect pulp capping on primary molars with deep dentin caries.
- Trial name
- NCT06325540
- Testing
- indirect pulp capping with theracal pt, indirect pulp capping with therabase, indirect pulp capping with biodentine
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Dentin Caries, Infection
Microbiological and Microscopic Evaluation of Atraumatic Restorative Treatment in Adult Dentition
Atraumatic Restorative Treatment (ART) was proposed as a new and effective method in the 1990s to provide conservative dental treatment to the people living in economically underdeveloped countries, due to lack of dental…
- Trial name
- NCT04813744
- Testing
- Atraumatic restorative treatment
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Dental Caries in Children, Tooth Diseases
Hall Technique or Modified Hall Technique of Deep Carious Lesions in Primary Molars
The purpose of this randomized clinical trial is to compare the clinical/radiographic success of Hall technique and modified Hall technique in the treatment of primary molars with deep dentine carious lesions in children…
- Conditions
- Dental Caries in Children, Tooth Diseases, Tooth Demineralization, Stomatognathic Diseases
- Trial name
- NCT05220865
- Testing
- Hall Technique, Modified Hall Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Dental Caries
Effect of Photodynamic Therapy With Low-level Laser on Infected Dentin in Primary Teeth: A Controlled Clinical Trial
The aim of the proposed study is to assess the clinical effect of photodynamic therapy (PDT) on dentin with carious lesions in primary teeth.
- Trial name
- NCT02734420
- Testing
- PapacarieMBlue and PDT, Toluidine Blue O and PDT, Laser
- Where
- Brazil
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho