Clinical trials: Carious Lesion
Elderly, Periodontal Disease
Oral Hygiene Assistance Training Program
This is an oral health study with a nursing home staff training program and product intervention.
- Conditions
- Elderly, Periodontal Disease, Gingivitis, Caries,Dental
- Trial name
- NCT07807397
- Testing
- Stannous Fluoride Toothpaste (SnF), sodium fluoride 5000 ppm, cetylpyridinium chloride (0.075%) and zinc alcohol free mouthwash
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Caries,Dental, Apical Periodontitis
Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Endodontics
The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine…
- Trial name
- NCT04105985
- Testing
- Kovanaze Nasal Spray, Articaine Injection
- Sponsor
- Virginia Commonwealth University
Dental Caries in Children
Partial or Complete Excavation of Deep Caries in Primary Molars
Background: The traditional approach of carious lesions with risk for progression has has been to excavate all infected and demineralised tissue before placement of the restoration.
- Trial name
- PBRN (NCT04614285)
- Testing
- Partial excavation
- Where
- Sweden
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Malaria
Providers' Compliance to Malaria Treatment
INDEPTH Network Effectiveness and Safety Studies in Africa (INESS) have demonstrated a substantial efficacy decay of Artemisinin based combination therapy (ACT) in Tanzania in 2012 (from efficacy of 98% to effectiveness of 18%).
- Trial name
- (PCMT) (NCT02298140)
- Testing
- SMS reminders
- Where
- Tanzania
- Volunteers
- 712 people
- Sponsor
- Ifakara Health Institute
Dental Caries Class II
A 2-year Clinical Impact of Bulk-fill Low-viscosity Resin Composite Liners in Class II Restorations.
This randomized clinical trial evaluated the clinical performance of class II resin composite restorations using bulk-fill high-viscosity ormocer versus methacrylate-based with or without a thin layer of bulk-fill low-viscosity…
- Trial name
- NCT06032689
- Testing
- Xtra-fill, x-base, Admira fusion x-tra
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Dental Caries
Primary Molars Restorations With Encapsulated or Hand-Mixed Glass Ionomer: Clinical Trial
The aim of this RCT is to evaluate the survival of different glass ionomer cement in minimally invasive restorations, with different handling characteristics: hand-mixed versus encapsulated.
- Trial name
- NCT02274142
- Testing
- Restoration with hand-mixed material, Restoration with Encapsulated material, Encapsulated glass ionomer cement (EQUIA - GC Corp).
- Where
- Brazil
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Caries
Clinical Assessment of Giomer Based Technology Versus Smart Bioactive Restoration in Carious Class V Cavities
This study will compare between S-PRG-containing injectable flowable resin composite (Beautifil Flow Plus X) and smart bioactive flowable resin composite (Activa bioactive restorative) through evaluation of the modified USPHS…
- Trial name
- NCT05466461
- Testing
- Beautifil Flow Plus X., Activa bioactive restorative
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Head & Neck Cancer, Head & Neck Squamous Cell Carcinoma
Longitudinal Oral Health Changes After Head and Neck Radiotherapy
This prospective observational study evaluates how head and neck radiotherapy affects oral health over time. Patients with head and neck cancer undergoing standard radiotherapy are followed from before treatment through multiple…
- Conditions
- Head & Neck Cancer, Head & Neck Squamous Cell Carcinoma, Periodontal Disease, Xerostomia
- Trial name
- HN-ORAL-RT (NCT07394842)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Dental Caries in Children, Economic Problems
Equal Oral Health in Children: The Hageby-model
Pregnant women - living in thecatchment area of a public dental clinic with known higher caries experience and generally lower socioeconomical status than at other dental clinics in the Region - are recruited for the study.
- Conditions
- Dental Caries in Children, Economic Problems, Infant Conditions, Child, Preschool
- Trial name
- EOH (NCT04389905)
- Testing
- Dental education - Motivational Interviewing
- Where
- Sweden
- Volunteers
- 667 people, healthy volunteers welcome
- Sponsor
- Mats Bågesund
Dental Caries, Composite Resins
Clinical Evaluation of Dentin Replacement Materials in Posterior Composite Restorations
This randomized controlled clinical trial is designed to clinically evaluate and compare the performance of five dentin replacement materials used beneath posterior composite restorations.
- Conditions
- Dental Caries, Composite Resins, Composite Restoration
- Trial name
- NCT07762651
- Testing
- Biodentine, ACTIVA BioACTIVE, glass ionomer cement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Management of Dental Caries of Primary Molars
Clinical Performance of a Flowable Bulk Fill Composite Versus a Highly Viscous Glass-ionomer Cement in Primary Molars
the study was conducted to compare and evaluate the clinical performance of EQUIA Forte and SDR® flow+ in class II cavities in primary molar
- Trial name
- NCT06166160
- Testing
- Bulk fill flowable composite SDR Dentsply sirona
- Where
- 2 sites in Egypt
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Preventive Oral Health
Oral Health Training Program for Pediatric Residents
The purpose of this study was to compare the effect of the addition of hands on training by a pediatric dentist on the pediatric residents skills, confidence, opinions and practice related to preventive oral health.
- Trial name
- NCT00846066
- Testing
- Hands on training, Web based training
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Dental Caries, Compliance Behavior
Treatment of Initial Caries Lesions on Proximal Surfaces of Primary and Permanent Posterior Teeth
This study aims to evaluate the effectiveness of 30% silver diamine fluoride in the treatment of clinically caries lesions in enamel, with radiographic image restricted to the enamel or the outer third of dentin on the proximal…
- Trial name
- NCT01477385
- Testing
- Resin Infiltration, 30% Silver Diammine Fluoride, Dental Flossing
- Where
- Brazil
- Volunteers
- 183 people
- Sponsor
- University of Sao Paulo
Decayed Teeth
Effect of Bone Marrow Mononuclear Cell Layer Seeded on Platelet-rich Fibrin on an Alveolar Socket After Extraction
Bone marrow aspiration from maxillary tuberosity will be centrifuged to separate the bone marrow mononuclear cell layer using the density gradient separation method, then it will be seeded in a platelet-rich fibrin membrane and…
- Trial name
- NCT05465421
- Testing
- bone marrow aspiration from maxillary tuberosity and BMMNCs separation to be seeded on PRF and used for socket preservation
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Educational and Preventive Session for Dental Caries, Oral Diseases
Oral Health Promotion Program in Schools in Polígono Sur
The objective of this observational study is to evaluate oral health before and after conducting an educational session on oral hygiene in schoolchildren from 3 schools in the Polígono Sur of Seville.
- Trial name
- OHPPSPS (NCT06797778)
- Where
- Spain
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- University of Seville
Dental Caries, Pulpotomies Primary Teeth
Ferric Sulfate and Sodium Hypochlorite Pulpotomies in Vital Primary Teeth
This study aims to compare the clinical and radiographic success of two commonly used pulpotomy agents, ferric sulfate (FS) and sodium hypochlorite (NaOCl), in vital primary molars.
- Trial name
- NCT07548008
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Marmara University
Dental Caries
Povidone Iodine for Caries Prevention
The goal of this clinical trial is to learn if Povidone Iodine works to prevent tooth decay and suppress the mouth germs responsible for tooth decay. The main questions it aims to answer are: 1.
- Trial name
- NCT07741409
- Testing
- Povidone Iodine 5% Soln,Top,Kit, Probiotics
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Jeffrey A. Banas
Dental Caries in Children
Evaluation of the Occlusal Effects of the Hall Technique and Investigation of Children's Satisfaction
Background: The Hall Technique (HT) is a non-invasive, easily applicable minimally invasive dentistry approach for managing dental caries in children.
- Trial name
- NCT06012409
- Testing
- Hall Technique Prefabricated Metal Crown
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Aydin Adnan Menderes University
Dental Caries
Educational Intervention in Preventing Early Childhood Caries
Objective: The aim of this study is to assess the effectiveness of an oral health educative intervention in preventing early childhood caries (ECC).
- Trial name
- NCT01502566
- Testing
- Education Intervention
- Where
- Brazil
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Dental Caries, Dry Mouth
Oral Health Intervention in Adult Primary Care
This study is a Stage III cRCT to test the efficacy of multi-level interventions at the practice- and provider-level to address low dental utilization (attendance) among Medicaid-enrolled older adults 55 years or older attending…
- Conditions
- Dental Caries, Dry Mouth, Periodontal Diseases, Bleeding Gum
- Trial name
- NCT06555029
- Testing
- EHR Changes, Medical Staff EHR Training, Clinician CSM theory-based didactic education and skills training, Standard ADA Oral Health Training
- Where
- United States
- Volunteers
- 929 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
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