Clinical trials: Carotenoid
Healthy
Provitamin A Absorption and Conversion With Avocados
Vitamin A is necessary in the human diet. The form of vitamin A found in fruits and vegetables is not "active" and must be converted to the active form in the human body.
- Trial name
- NCT01432210
- Testing
- Post-prandial Feeding Study
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Oxidative DNA Damage
Biological Functions of Carotenoids in Humans
This study will examine the the efficiency fo absorption of major plant pigments, carotenoids, (lutein, beta-carotene and lycopene)and will measure the biological functions of carotenoids in healthy women in response to an 8-week…
- Trial name
- NCT00356252
- Testing
- mixed carotenoids
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tufts University
Healthy
The MULTINUTRIENT Maize Project: Results of Human Feeding Trial
The main objective of this human trial is the demonstration that β-carotene in fortified maize has good bioavailability as a plant source of vitamin A and that when humans ingest the biofortified product retinol levels are higher…
- Trial name
- MAIZE (NCT02373943)
- Testing
- β-carotene biofortified maize, β-carotene supplemented maize, Normal (non biofortified) maize without added β-carotene
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Intrinsically Labeled Spirulina
Vitamin A Value of Spirulina Carotenoids in Humans
The goal of this protocol is to determine the vitamin A value (equivalence) of spirulina. The investigation will use intrinsically deuterium labeled spirulina and an isotope vitamin A reference dose, 13C10- retinyl acetate (13C10…
- Trial name
- NCT00680277
- Testing
- spirulina ß-carotene
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tufts University
Mild Cognitive Impairment
The Effects of a Carotenoid Intervention on Cognitive Function
Past research suggests that retinal lutein levels are related to cognitive function as measured via behavioral tests. The goal of the present study is to investigate the relationship between lutein and cognitive function in a…
- Trial name
- NCT02023645
- Testing
- active supplement
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Healthy
Bioavailability of Carotenoids and Flavonoids From Fresh Oranges and Orange Juice.
The study was designed as a randomized 2-way cross-over study to assess the bioavailability of carotenoids and flavonoids from sweet oranges and orange juice.
- Trial name
- NCT02380144
- Testing
- Fresh orange fruit and pasteurized fruit juice
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Oxidative Stress, Atherosclerosis
Effect of Short-term Annatto Carotenoids Supplementation on Oxidative Stress Status in Healthy Individuals
Low-density lipoprotein (LDL) oxidation has a pivotal role in atherosclerosis development. There is a relationship between carotenoids serum concentration and cardiovascular (CV) benefits, mainly in oxidized LDL (oxLDL)…
- Trial name
- NCT03820245
- Testing
- Bixin, Norbixin, Lycopene
- Where
- Brazil
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Beta-cryptoxanthin Supplementation
Beta-cryptoxanthin Supplement: Absorption and Function
Beta-cryptoxanthin (BCX) is a naturally occurring member of the carotenoid family, found in a wide range of fruits and vegetables.
- Trial name
- BETA+ (NCT05046457)
- Testing
- Beta-cryptoxanthin (BCX)
- Where
- Singapore
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Biological Availability
Bioavailability of Carotenoids Present in Mamey Sapote (Pouteria Sapota (Jacq.) H. E. Moore & Stearn) Fruit
The goal of the study is to determine if mamey sapote fruit, rich in rare potentially provitamin A keto-carotenoids, is a good source of vitamin A in humans.
- Trial name
- NCT03873909
- Testing
- Fruit Smoothie, Matrix-Free Shake
- Where
- 2 sites in Costa Rica, Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Iron Absorption
Effects of Vitamin A and Carotenoids on Iron Absorption
The objective of this study is to investigate the effect of vitamin A and carotenoids on iron absorption in healthy subjects with low and normal vitamin A status.
- Trial name
- NCT01493297
- Testing
- Labeled iron solutions
- Where
- Venezuela
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Photoaging
Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and Elasticity
This study is a double-blind placebo controlled study to assess whether oral astaxanthin can improve skin hydration, skin elasticity, improve skin pigmentation, and reduce facial redness.
- Trial name
- NCT05882084
- Testing
- Astaxanthin 6 mg daily
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Healthy Nutrition, Healthy Diet
Baylor Infant and Toddler Biomarker of Nutrition Study
Young children rely on their foods and drinks for the nutrients they need to grow, like energy, protein, vitamins, and minerals.
- Trial name
- BITBONS (NCT05869760)
- Testing
- Carotenoid Intake, Serum carotenoid concentrations
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Fruit and Vegetable Consumption in Children, Fruit and Vegetable Consumption
Fruit and Vegetable Study - Pilot
Arizona State University is studying how local schools and grocery stores can work together to promote fruits and vegetables and support healthy eating among children and families.
- Conditions
- Fruit and Vegetable Consumption in Children, Fruit and Vegetable Consumption, Fruit and Vegetable Selection in the Lunchroom, Caregiver Nutrition
- Trial name
- FFVP+ Pilot (NCT07727746)
- Testing
- FFVP+, FFVP-only
- Where
- United States
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Biological Availability of Vitamins and Micronutrients
Effect of Genetic Variants on Fat-soluble Vitamin Bioavailability
The aim was to identify minor genetic variations (single nucleotide polymorphisms) that explain the interindividual variability in bioavailability of fat soluble micronutrients (fat soluble vitamins and carotenoids).
- Trial name
- VITAGENES (NCT02100774)
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Lifestyle Risk Reduction
Analysis of Correlation Between Skin Carotenoid Level and Basic Indicators of Health Status Related to Lifestyle in Vietnamese: An Observational Study
To clarify the relationship between vegetable intake and lifestyle-related disease in Vietnam, we measure skin carotenoid levels and basic indicators of health status related to lifestyle and analyze the correlation between them.
- Trial name
- NCT06271070
- Testing
- Non-intervention
- Where
- Vietnam
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- KAGOME CO., LTD.
Age-related Macular Degeneration
Consumption of Eggs Rich in Lutein and Omega-3 Fatty Acids on the Macular Pigment
This study is to determine the impact of the consumption of eggs rich in lutein/zeaxanthin from lucerne protein concentrate and DHA from microalgae on the plasma levels of these compounds but also on the macular pigment optical…
- Trial name
- ALGOVUE (NCT01480700)
- Testing
- Nutritional study
- Where
- France
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Eye Health, Age-related Macular Degeneration
Impact of Regular Consumption of Grapes on Eye Health in Singapore Older Adults
Aging epidemics in Singapore are rapidly increasing and Age-related macular degeneration (AMD) prevalence is significantly associated with older age.
- Trial name
- NCT05064865
- Testing
- Freeze-dried table grape powder
- Where
- Singapore
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Vitamin A Deficiency
Vitamin A Equivalence of Plant Carotenoids in Children
Our objectives will be to test the following hypotheses and to make the following determinations: (1) The absorption and bio-conversion of provitamin A carotenes taken by children are different between spinach, Golden Rice, and…
- Trial name
- NCT00680212
- Testing
- dietary carotenoids, spinach, rice, and synthetic beta-carotene
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Tufts University
Vitamin A Deficiency, Low Serum Retinol
Efficacy of β-carotene Biofortified Maize in Reducing Vitamin A Deficiency Among Children
The purpose of this cluster-randomized trial is to examine whether daily consumption of β-carotene biofortified maize flour can reduce the prevalence of vitamin A deficiency and improve the vitamin A status and among 4-8 year old…
- Trial name
- NCT01695148
- Testing
- β-Carotene Biofortified Maize Flour, White Maize Flour
- Where
- Zambia
- Volunteers
- 1,228 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Overweight , Obesity, Antioxidant Status
Impact of Antioxidant-rich Supplementation on Skin Carotenoids Status, Antioxidant Status and Cardiometabolic Health in Overweight and Obese Individuals
This study aims to evaluate the effects of antioxidant-rich supplementation on skin carotenoid status, antioxidant status, and cardiometabolic health in overweight and obese individuals.
- Trial name
- NCT07748468
- Testing
- Antioxidant-rich supplementation Element, Antioxidant-rich supplementation Optimal
- Where
- Singapore
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- National University of Singapore