Clinical trials: Carpal Tunnel Release
Carpal Tunnel Syndrome
Dual Task During Resistance Training in CTR
Carpal tunnel syndrome (CTS) is a highly prevalent peripheral compressive neuropathy of the upper extremity. CTS is characterised by the presence of pain, tingling sensations and paraesthesia in the median nerve territory.
- Trial name
- DTRTCTR (NCT05592184)
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- University of Valencia
Carpal Tunnel Syndrome Bilateral
Neurological Outcomes Following Carpal Tunnel Wound-closure Techniques
single-centre randomised prospective trial will conducted at the University Hospital of Split in Croatia. The investigators plan to enrol 100 patients, randomly assigned to suture-based wound closure (n=50) or tissue…
- Trial name
- NCT05808855
- Testing
- two-component skin adhesive Glubran Tiss 2®, skin stitched with transcutaneous nylon suture
- Where
- 2 sites in Croatia
- Volunteers
- 100 people
- Sponsor
- University of Split, School of Medicine
Carpal Tunnel
Short- to Medium-term Outcome of Minimally Invasive Carpal Tunnel Release
The aim of the study is to determine whether minimally invasive, ultrasound-guided thread carpal tunnel release leads to faster functional recovery compared to standard open and endoscopic techniques in patients with carpal…
- Trial name
- NCT06997172
- Testing
- TCTR (thread carpal tunnel release), Standard-of-care
- Where
- Switzerland
- Volunteers
- 61 people
- Sponsor
- University Hospital, Basel, Switzerland
Carpal Tunnel Syndrome, Incision
Comparing a Modified Mini-incision Approach Versus the Conventional Approach for Carpal Tunnel Release
Carpal tunnel syndrome (CTS) is the commonest nerve compression syndrome in the upper limbs, and carpal tunnel decompression is one of the most prevalent upper limb surgical interventions.
- Trial name
- NCT06114823
- Testing
- carpal tunnel release mini-incision, carpal tunnel release conventional incision
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Mansoura University
Carpal Tunnel Syndrome, Anesthesia, Local
Efficacy of Local Direct Median Nerve Block
Carpal tunnel syndrome is the most common compressive neuropathy. Carpal tunnel release is indicated when failed conservative treatment.
- Trial name
- NCT04453462
- Testing
- Endoscopic carpal tunnel release under local direct median nerve block, Endoscopic carpal tunnel release under brachial plexus block
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Thammasat University
Carpal Tunnel Syndrome
Single-portal Endoscopic Carpal Tunnel Release Versus Knifelight for Carpal Tunnel Syndrome. A Randomized Control Trial
The purpose of this study is to determine whether Single-portal Endoscopic Carpal Tunnel Release (Agee technique, SmartRelease™, MicroAire) and mini-open technique (Knifelight®, Stryker) are equally effective and safe surgical…
- Trial name
- CTS-HV (NCT01756820)
- Testing
- Single-portal Endoscopic Carpal Tunnel Release (Microaire®), Knifelight
- Where
- Greece
- Sponsor
- University of Ioannina
Carpal Tunnel, Carpal Tunnel Syndrome
Comparing Superficial vs. Deep Local Anesthetic Infiltration to Improve Patient Experience During Carpal Tunnel Release
Hypothesis: When comparing superficial infiltration of local anesthetic to superficial and deep infiltration of local anesthetic in the setting of carpal tunnel release, the null hypothesis is that there will be no significant…
- Trial name
- NCT04201652
- Testing
- Superficial local anesthetic infiltration, Deep local anesthetic infiltration
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- University of Saskatchewan
Carpal Tunnel Surgery, Median Nerve Compression
Efficacy of Proximal Median Nerve Release
A multi-center randomized controlled clinical trial which determines the efficacy of proximal median nerve release in patients with persistent proximal median nerve compression.
- Conditions
- Carpal Tunnel Surgery, Median Nerve Compression, Median Nerve Entrapment
- Trial name
- PROMER (NCT07484100)
- Testing
- Proximal median nerve release, Physiotherapy
- Where
- 2 sites in Finland
- Volunteers
- 160 people
- Sponsor
- Tampere University Hospital
Postoperative Pain, Carpal Tunnel Release
Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries
The purpose of this study is to determine the efficacy of intra-operative administration of IV tylenol and/or IV toradol in minimizing post-operative pain for carpal tunnel patients and distal radius fracture patients.
- Conditions
- Postoperative Pain, Carpal Tunnel Release, Distal Radius Fracture
- Trial name
- NCT02313675
- Testing
- Acetaminophen, Ketorolac Tromethamine, Saline
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- John Fowler
Carpal Tunnel Syndrome, Perioperative/Postoperative Complications
Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release
This study seeks to perform an appropriately-powered study to evaluate any clinical difference between continuous cooling therapy and traditional ice for treatment of post-operative pain in open CTR surgery.
- Trial name
- NCT05783245
- Testing
- Polarcare Machine, Standard of care ice therapy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Chicago
Carpal Tunnel Syndrome
Splinting After Mini-Open Carpal Tunnel Release
The purpose of this study is to determine if any difference exists among 3 different postoperative splinting regimens- no splint, removable splint, and plaster non-removable splint- following mini-open carpal tunnel release (CTR)…
- Trial name
- NCT02885701
- Testing
- No Splint, Removable Splint, Non-removable Splint
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Anthony L. Logli
Carpal Tunnel Syndrome
Percutaneous Treatment of Carpal Tunnel Syndrome With Scan
The objective of the study is to evaluate in patients suffering from carpal tunnel syndrome resistant to medical treatment, clinical course after percutaneous treatment under ultrasound guidance.
- Trial name
- ECHOCARPE (NCT02514317)
- Testing
- percutaneous treatment, Ultrasound
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Caen
Carpal Tunnel Syndrome (CTS)
Comparative Outcomes of Endoscopic and Open Carpal Tunnel Release with Neurotrophic Supplementation in Severe Carpal Tunnel Syndrome
This study addresses the pressing clinical question of optimizing surgical and pharmacological interventions for severe Carpal Tunnel Syndrome (CTS), a prevalent and debilitating condition caused by median nerve compression.
- Trial name
- NCT06902831
- Testing
- Endoscopic Carpal Tunnel Release, Open carpal tunnel release, Neurotrophic supplementation
- Where
- Italy
- Volunteers
- 497 people
- Sponsor
- University of Bari
Carpal Tunnel Syndrome
Flexor Tenosynovectomy to Treat Recurrent Carpal Tunnel Syndrome
The purpose of this study is to collect data on the clinical and functional outcomes of surgical management for recurrent carpal tunnel syndrome (CTS) using flexor tenosynovectomy.
- Trial name
- NCT03757416
- Testing
- Data collection
- Volunteers
- 2 people
- Sponsor
- University of Tennessee
Transthyretin Amyloidosis, Carpal Tunnel Syndrome
Transthyretin Cardiac Amyloidosis in Patients With Idiopathic Carpal Tunnel Syndrome Referred for Release Surgery
This study will determine the prevalence of transthyretin amyloidosis in pathology of the transverse carpal ligament and cardiac involvement using natriuretic peptides, electrocardiography and echocardiography in patients…
- Trial name
- PRATHYC (NCT04611204)
- Testing
- Descriptive cohort
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Toulouse
Carpal Tunnel Syndrome (CTS)
Effectiveness of PErcutaneous Ultrasound-guided Carpal Tunnel Release: a Non-inferiority Study With Surgery as Comparator
Carpal tunnel syndrome is a common condition caused by compression of the median nerve. Tingling in the first three or four fingers, usually at night or upon waking, is the most frequent symptom.
- Trial name
- EPEC (NCT07668310)
- Testing
- Carpal tunnel surgery, Questionnaires
- Where
- France
- Volunteers
- 7 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Musculoskeletal Diseases, Median Nerve Disease
Comparison of Ultrasound-Guided Injection With Median Nerve Decompression Surgery in Carpal Tunnel Syndrome
The aim of this study is to compare ultrasound-guided perineural injection of the median nerve with classic minimal incision surgical technique for median nerve decompression in patients diagnosed with mild, moderate, and severe…
- Conditions
- Musculoskeletal Diseases, Median Nerve Disease, Carpal Tunnel Syndrome, Ultrasound-Guided Injection
- Trial name
- NCT06243848
- Testing
- Minimal Incision Surgery for median nerve decompression, Ultrasound-guided perineural injection with 5 cc 5% Dextrose
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Afyonkarahisar Health Sciences University
Carpal Tunnel Syndrome (CTS)
Changes in Sleep, Fatigue, Kinesiophobia, and Upper Extremity Function After Carpal Tunnel Release
Carpal tunnel syndrome can cause hand pain, numbness, weakness, sleep disturbance, fatigue, fear of movement, and difficulty performing daily activities.
- Trial name
- CTS-RECOVER (NCT07806071)
- Testing
- Carpal Tunnel Release Surgery
- Volunteers
- 100 people
- Sponsor
- Istanbul Medipol University Hospital
Carpal Tunnel Syndrome
Surgical Dressings After Endoscopic Carpal Tunnel Release
Carpal tunnel syndrome (CTS) is the most common compressive neuropathy in the upper extremity. While carpal tunnel release (CTR), both open (OCTR) and endoscopic (ECTR), is safe and effective, there are questions regarding the…
- Trial name
- NCT04070924
- Testing
- Bandaid, Conventional bulky soft tissue dressing
- Sponsor
- Chris Grandizio
Carpal Tunnel Syndrome (CTS), Lacertus Syndrome
MeDe Study: Comparing Median Nerve Decompression at the Carpal Tunnel Alone Versus Median Nerve Decompression at Both the Carpal Tunnel and Lacertus Fibrosis in Adults With Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is a condition that can cause pain, numbness, or tingling in the hand and wrist. The most common surgery for CTS is called carpal tunnel release, which aims to relieve pressure on the main nerve in…
- Trial name
- MeDe (NCT07594821)
- Testing
- Carpal tunnel release, Combined carpal tunnel and lacertus release
- Where
- 2 sites in Netherlands
- Volunteers
- 110 people
- Sponsor
- Maasstad Hospital